Abstract: Candida spp. are common and aggressive pathogens. Because of the growing resistance of Candida spp. to current antifungals, novel targets, found in Candida spp. but not in humans or other flora, have to be identified. The alternative oxidase (AOX) is one such possibility. This enzyme is insensitive to cyanide, but is sensitive to compounds such as salicylhydroxamic acid (SHAM), disulfiram and n-alkyl gallates. The growth each of six Candida spp. was inhibited significantly by ~13 mM SHAM or 2 mM cyanide, albeit to differing extents. In C. dubliniensis, C. krusei and C. tropicalis the rate of O2 uptake was inhibited by 18-36% by 25 mM SHAM, but this had little or no effect on C. glabrata, C. guilliermondii or C. parapsilosis. Although SHAM substantially inhibited the growth of Candida spp., it is unlikely that the inhibition of AOX was the cause. Salicylhydroxamic acid is used therapeutically in the treatment of urinary tract infections and urolithiasis, but it also has some potential in the treatment of Candida spp. infection.
Abstract: Environmental responsibility includes improvement of environmental performance in order to reduce environmental impact. This paper gives a short review of some important environmental objectives, targets and actions that modern shipping company should follow.
Abstract: In this paper, we study the formation control problem
for car-like mobile robots. A team of nonholonomic mobile robots navigate in a terrain with obstacles, while maintaining a desired
formation, using a leader-following strategy. A set of artificial potential field functions is proposed using the direct Lyapunov
method for the avoidance of obstacles and attraction to their designated targets. The effectiveness of the proposed control laws to verify the feasibility of the model is demonstrated through computer simulations
Abstract: In this note, a theoretical model for analyzing of
normal penetration of the ogive – nose projectile into metallic targets
is presented .The failure is assumed to be asymmetry petalling and
the analysis is performed by using the energy balance and work done
.The work done consist of the work required for plastic deformation
Wp, the work for transferring the matter to new position Wd and the
work for bending of the petals Wb. In several studies, it has been
shown that we can neglect the loss of energy by temperature.
In this present study, in first, by assuming the crater formation
after perforation, the value of work done is calculated during the
normal penetration of conical projectiles into thin metallic targets.
Then the value of residual velocity and ballistic limit of the projectile
is predicated by using the energy balance. In final, theoretical and
experimental results is compared.
Abstract: In July 1, 2007, Taiwan Stock Exchange (TWSE) on
market observation post system (MOPS) adds a new "Financial
reference database" for investors to do investment reference. This
database as a warning to public offering companies listed on the
public financial information and it original within eight targets. In
this paper, this database provided by the indicators for the application
of company financial crisis early warning model verify that the
database provided by the indicator forecast for the financial crisis,
whether or not companies have a high accuracy rate as opposed to
domestic and foreign scholars have positive results. There is use of
Logistic Regression Model application of the financial early warning
model, in which no joined back-conditions is the first model, joined it
in is the second model, has been taken occurred in the financial crisis
of companies to research samples and then business took place
before the financial crisis point with T-1 and T-2 sample data to do
positive analysis. The results show that this database provided the
debt ratio and net per share for the best forecast variables.
Abstract: Customarily, the LMTD correction factor, FT, is used
to screen alternative designs for a heat exchanger. Designs with
unacceptably low FT values are discarded. In this paper, authors have
proposed a more fundamental criterion, based on feasibility of a
multipass exchanger as the only criteria, followed by economic
optimization. This criterion, coupled with asymptotic energy targets,
provide the complete optimization space in a heat exchanger network
(HEN), where cost-optimization of HEN can be performed with only
Heat Recovery Approach temperature (HRAT) and number-of-shells
as variables.
Abstract: Khatunabad area is situated geologically in Urmieh-
Dokhtar magmatic belt in NW of Iran. In this research, studied area
has been investigated in order to recognize the potential copper and
molybdenum-bearing target areas. The survey layers include the
lithologic units, alteration, geochemical result, tectonics and copper
and molybdenum occurrence. As an accurate decision can have a
considerable effect on exploration plans, so in this efforts have been
made to make use of new combination method. For this purpose, the
analytical hierarchy process was used and revealed highly potential
copper and molybdenum mineralization areas. Based on achieved
results, geological perspective in north of studied area is appropriate
for advance stage, especially for subsurface exploration in future.
Abstract: The logistical requirements placed on industrial manufacturing companies are steadily increasing. In order to meet those requirements, a consistent and efficient concept is necessary for production control. Set up properly, production control offers considerable potential with respect to achieving the logistical targets. As experience with the many production control methods already in existence and their compatibility is, however, often inadequate, this article describes a systematic approach to the configuration of production control based on the Lödding model. This model enables production control to be set up individually to suit a company and the requirements. It therefore permits today-s demands regarding logistical performance to be met.
Abstract: Existing ground movement surveillance technologies
at airports are subjected to limitations due to shadowing effects or
multiple reflections. Therefore, there is a strong demand for a new
sensing technology, which will be cost effective and will provide
detection of non-cooperative targets under any weather conditions.
This paper aims to present a new intelligent system, developed
within the framework of the EC-funded ISMAEL project, which is
based on a new magnetic sensing technology and provides detection,
tracking and automatic classification of targets moving on the airport
surface. The system is currently being installed at two European
airports. Initial experimental results under real airport traffic
demonstrate the great potential of the proposed system.
Abstract: Abu Dhabi is one of the fastest developed cities in the region. On top of all the current and future environmental challenges, Abu Dhabi aims to be among the top governments in the world in sustainable development. Abu Dhabi plans to create an attractive, livable and sustainable managed urban environment in which all necessary services and infrastructure are provided in a sustainable and timely manner. Abu Dhabi is engaged in a difficult challenge to develop credible environmental indicators that would assess the ambitious environmental targets. The aim of those indicators is to provide reliable guidance to decision makers and the public concerning key factors that determine the state of urban environment and identify major areas for policy intervention. In order to ensure sustainable development in UAE in general, and of Abu Dhabi City in particular, relevant and contextual environmental indicators need to be carefully considered. These indicators provide a gauge at a national government scale of how close countries are to establish environmental policy goals. The environment indicators assist city decision-making in such areas as identification of significant environmental aspects and observation of environmental performance trends. Those can help to find ways of reducing environmental pollution and in improving eco-efficiency. This paper outlines recent strategies implemented in Abu Dhabi that aims to improve the sustainable performance of the city-s built environment. The paper explores the variety of current and possible indicators at different levels and their roles in the development of the city.
Abstract: Decision support based upon risk analysis into
comparison of the electricity generation from different renewable
energy technologies can provide information about their effects on
the environment and society. The aim of this paper is to develop the
assessment framework regarding risks to health and environment,
and the society-s benefits of the electric power plant generation from
different renewable sources. The multicriteria framework to
multiattribute risk analysis technique and the decision analysis
interview technique are applied in order to support the decisionmaking
process for the implementing renewable energy projects to
the Bangkok case study. Having analyses the local conditions and
appropriate technologies, five renewable power plants are postulated
as options. As this work demonstrates, the analysis can provide a tool
to aid decision-makers for achieving targets related to promote
sustainable energy system.
Abstract: Evolvable Hardware (EHW) has been regarded as adaptive system acquired by wide application market. Consumer market of any good requires diversity to satisfy consumers- preferences. Adaptation of EHW is a key technology that could provide individual approach to every particular user. This situation raises a question: how to set target for evolutionary algorithm? The existing techniques do not allow consumer to influence evolutionary process. Only designer at the moment is capable to influence the evolution. The proposed consumer-triggered evolution overcomes this problem by introducing new features to EHW that help adaptive system to obtain targets during consumer stage. Classification of EHW is given according to responsiveness, imitation of human behavior and target circuit response. Home intelligent water heating system is considered as an example.
Abstract: Frequent machine breakdowns, low plant availability and increased overtime are a great threat to a manufacturing plant as they increase operating costs of an industry. The main aim of this study was to improve Overall Equipment Effectiveness (OEE) at a manufacturing company through the implementation of innovative maintenance strategies. A case study approach was used. The paper focuses on improving the maintenance in a manufacturing set up using an innovative maintenance regime mix to improve overall equipment effectiveness. Interviews, reviewing documentation and historical records, direct and participatory observation were used as data collection methods during the research. Usually production is based on the total kilowatt of motors produced per day. The target kilowatt at 91% availability is 75 Kilowatts a day. Reduced demand and lack of raw materials particularly imported items are adversely affecting the manufacturing operations. The company had to reset its targets from the usual figure of 250 Kilowatt per day to mere 75 per day due to lower availability of machines as result of breakdowns as well as lack of raw materials. The price reductions and uncertainties as well as general machine breakdowns further lowered production. Some recommendations were given. For instance, employee empowerment in the company will enhance responsibility and authority to improve and totally eliminate the six big losses. If the maintenance department is to realise its proper function in a progressive, innovative industrial society, then its personnel must be continuously trained to meet current needs as well as future requirements. To make the maintenance planning system effective, it is essential to keep track of all the corrective maintenance jobs and preventive maintenance inspections. For large processing plants these cannot be handled manually. It was therefore recommended that the company implement (Computerised Maintenance Management System) CMMS.
Abstract: A challenging problem in radar signal processing is to
achieve reliable target detection in the presence of interferences. In
this paper, we propose a novel algorithm for automatic censoring of
radar interfering targets in log-normal clutter. The proposed
algorithm, termed the forward automatic censored cell averaging
detector (F-ACCAD), consists of two steps: removing the corrupted
reference cells (censoring) and the actual detection. Both steps are
performed dynamically by using a suitable set of ranked cells to
estimate the unknown background level and set the adaptive
thresholds accordingly. The F-ACCAD algorithm does not require
any prior information about the clutter parameters nor does it require
the number of interfering targets. The effectiveness of the F-ACCAD
algorithm is assessed by computing, using Monte Carlo simulations,
the probability of censoring and the probability of detection in
different background environments.
Abstract: An array antenna system with innovative signal
processing can improve the resolution of a source direction of arrival
(DoA) estimation. High resolution techniques take the advantage of
array antenna structures to better process the incoming waves. They
also have the capability to identify the direction of multiple targets.
This paper investigates performance of the DOA estimation
algorithm namely; Capon and MUSIC on the uniform linear array
(ULA). The simulation results show that in Capon and MUSIC
algorithm the resolution of the DOA techniques improves as number
of snapshots, number of array elements, signal-to-noise ratio and
separation angle between the two sources θ increases.
Abstract: In Korea, the technology of a load fo nuclear power plant has been being developed.
automatic controller which is able to control temperature and axial power distribution was developed. identification algorithm and a model predictive contact former transforms the nuclear reactor status into
numerically. And the latter uses them and ge
manipulated values such as two kinds of control ro
this automatic controller, the performance of a coperation was evaluated. As a result, the automatic generated model parameters of a nuclear react to nuclear reactor average temperature and axial power the desired targets during a daily load follow.
Abstract: Reservoirs with high pressures and temperatures
(HPHT) that were considered to be atypical in the past are now
frequent targets for exploration. For downhole oilfield drilling tools
and components, the temperature and pressure affect the mechanical
strength. To address this issue, a finite element analysis (FEA) for
206.84 MPa (30 ksi) pressure and 165°C has been performed on the
pressure housing of the measurement-while-drilling/logging-whiledrilling
(MWD/LWD) density tool.
The density tool is a MWD/LWD sensor that measures the density
of the formation. One of the components of the density tool is the
pressure housing that is positioned in the tool. The FEA results are
compared with the experimental test performed on the pressure
housing of the density tool. Past results show a close match between
the numerical results and the experimental test. This FEA model can
be used for extreme HPHT and ultra HPHT analyses, and/or optimal
design changes.
Abstract: “Web of Trust" is one of the recognized goals for
Web 2.0. It aims to make it possible for the people to take
responsibility for what they publish on the web, including
organizations, businesses and individual users. These objectives,
among others, drive most of the technologies and protocols recently
standardized by the governing bodies. One of the great advantages of
Web infrastructure is decentralization of publication. The primary
motivation behind Web 2.0 is to assist the people to add contents for
Collective Intelligence (CI) while providing mechanisms to link
content with people for evaluations and accountability of
information. Such structure of contents will interconnect users and
contents so that users can use contents to find participants and vice
versa. This paper proposes conceptual information storage and
linking model, based on decentralized information structure, that
links contents and people together. The model uses FOAF, Atom,
RDF and RDFS and can be used as a blueprint to develop Web 2.0
applications for any e-domain. However, primary target for this
paper is online trust evaluation domain. The proposed model targets
to assist the individuals to establish “Web of Trust" in online trust
domain.
Abstract: Traditionally, terror groups have been formed by ideologically aligned actors who perceive a lack of options for achieving political or social change. However, terrorist attacks have been increasingly carried out by small groups of actors or lone individuals who may be only ideologically affiliated with larger, formal terrorist organizations. The formation of these groups represents the inverse of traditional organizational growth, whereby structural de-evolution within issue-based organizations leads to the formation of small, independent terror cells. Ideological franchising – the bypassing of formal affiliation to the “parent" organization – represents the de-evolution of traditional concepts of organizational structure in favor of an organic, independent, and focused unit. Traditional definitions of dark networks that are issue-based include focus on an identified goal, commitment to achieving this goal through unrestrained actions, and selection of symbolic targets. The next step in the de-evolution of small dark networks is the miniorganization, consisting of only a handful of actors working toward a common, violent goal. Information-sharing through social media platforms, coupled with civil liberties of democratic nations, provide the communication systems, access to information, and freedom of movement necessary for small dark networks to flourish without the aid of a parent organization. As attacks such as the 7/7 bombings demonstrate the effectiveness of small dark networks, terrorist actors will feel increasingly comfortable aligning with an ideology only, without formally organizing. The natural result of this de-evolving organization is the single actor event, where an individual seems to subscribe to a larger organization-s violent ideology with little or no formal ties.
Abstract: Research results and optimal parameters investigation
of laser cut and profiling of diamond and quartz substrates by
femtosecond laser pulses are presented. Profiles 10 μm in width, ~25
μm in depth and several millimeters long were made. Investigation of
boundaries quality has been carried out with the use of AFM
«Vecco». Possibility of technological formation of profiles and
micro-holes in diamond and quartz substrates with nanometer-scale
boundaries is shown. Experimental results of multilayer dielectric
cover treatment are also presented. Possibility of precise upper layer
(thickness of 70–140 nm) removal is demonstrated. Processes of thin
metal film (60 nm and 350 nm thick) treatment are considered.
Isolation tracks (conductance ~ 10-11 S) 1.6–2.5 μm in width in
conductive metal layers are formed.