Abstract: Cadmium (II) (Cd) is one of the major toxic elemental
pollutants, which is hazardous for humans, animals and plants. γ-
Polyglutamic acid (γ-PGA) is an extracellular biopolymer produced
by several species of Bacillus which has been reported to be an
effective biosorbent for metal ions. The effect of γ-PGA on growth of
rice grown under laboratory conditions was investigated. Rice seeds
were germinated and then grown at 30±1°C on filter paper soaked
with Cd solution and γ-PGA for 7 days. The result showed that Cd
significantly inhibited the growth of roots, shoots by reducing root,
and shoot lengths. Fresh and dry weights also decreased compared
with control; however, the addition of 500 mg·L-1 γ-PGA alleviated
rice seedlings from the adverse effects of Cd. The analysis of
physiological traits revealed that Cd caused a decrease in the total
chlorophyll and soluble protein contents and amylase activities in all
treatments. The Cd content in seedling tissues increased for the Cd
250 μM treatment (P
Abstract: This study was carried out to investigate the adverse
effect of industrial wastewater on surface water quality in Gebeng
industrial estate, Pahang, Malaysia. Surface water was collected from
six sampling stations. Physicochemical parameters were
characterized based on in-situ and ex-situ analysis according to
standard methods by American Public Health Association (APHA).
Selected heavy metals were determined by using Inductively Coupled
Plasma Mass Spectrometry (ICP MS). The results revealed that the
concentration of heavy metals such as Pb, Cu, Cd, Cr and Hg were
high in samples. The results also showed that the value of Pb and Hg
were higher in the wet season in comparison to dry season.
According to Malaysia National Water Quality Standard (NWQS)
and Water Quality Index (WQI) all the sampling station were
categorized as class IV (highly polluted). The present study revealed
that the adverse effects of careless disposal of wastes and directly
discharge of effluents affected on surface water quality. Therefore,
the authorities should implement the laws to ensure the proper
practices of wastewater management for environmental sustainability
around the study area.
Abstract: Chrome tannery wastewater causes serious environmental hazard due to its high pollution potential. As a result, rigorous treatment is necessary for abatement of pollution from this type of wastewater. There are many research studies on chrome tannery wastewater treatment in the field of physical, chemical, and biological methods. In general, biological treatment process is found ineffective for direct application because of adverse effects by toxic chromium, sulphide, chloride etc. However, biological methods were employed mainly for a few sub processes generating significant amount of organic matter and without chromium, chlorides etc. In this context the present paper reviews the characteristics feature and pollution potential of wastewater generated from chrome tannery units and treatment of the same. The different biological processes used earlier and their chronological development for treatment of the chrome tannery wastewater are thoroughly reviewed in this paper. In this regard, the scope of hybrid bioreactor - an advanced technology option has also been explored, as this kind of treatment is well suited for the wastewater having inhibitory substances.
Abstract: Although, lanthanum carbonate has not been approved
by the FDA for treatment of hyperphosphatemia, we prospectively
evaluated the efficacy of the combination of Calcium hydroxyapatite
(CHAp) and Lanthanum Carbonate (LaC) for the treatment of
hyperphosphatemia on mice. CHAp was prepared by co-precipitation
method using Ca(OH)2, H3PO4, NH4OH with calcination at 1200ºC.
Lanthanum carbonate was prepared by chemical method using
NaHCO3 and LaCl3 at low pH environment, below 4.0. The
structures were characterized by FTIR spectra and SEM -EDX
analysis. The study group included 16 subjects-mice divided into four
groups according to the administered substance: lanthanum carbonate
(group A), CHAp (group B), lanthanum carbonate + CHAp (group C)
and salt water (group D). The results indicate a phosphate decrease
when subjects (mice) were treated with CHAp and lanthanum
carbonate (0.5% CMC), in a single dose of 1500 mg/kg. Serum
phosphate concentration decreased [(from 4.5 ± 0.8 mg/dL) to
4.05 ± 0.2 mg/dL), P < 0.01] in group A and in group C (to 3.6
± 0.2 mg/dL) at 12 hours from the administration. The combination
of CHAp and lanthanum carbonate is a suitable regimen for
hyperphosphatemia treatment because it avoids both the
hypercalcemia of CaCO3 and the adverse effects of CHAp.
Abstract: The management of Helicobacter pylori (H. pylori)
eradication is still a matter of discussion, full effectiveness is rarely
achieved, and it has many adverse effects. The use of probiotics may
be associated with better eradication rates and possibly prevention of
adverse events due to antibiotic therapy. The present clinical study
was undertaken to evaluate the efficacy of a specially designed
fermented milk product, containing Bifidobacterium lactis B420, on
the eradication of H. pylori infection in a prospective, randomized,
double-blind, controlled study in humans. Four test fermented milks
(FM) were specially designed in which counts of viable cells in all
products were 10^10 Log CFU. 100 mL-1 for Bifidobacterium lactis -
Bifidobacterium species 420. 190 subjects infected with H. pylori,
with previous diagnosis of functional dyspepsia according to Rome
III criteria entered the study. Bifidobacterium lactis B420,
administered twice a day for 90 days was not able to eradicate H.
pylori in Brazilian patients with functional dyspepsia.
Abstract: This study evaluated the use of raw or processed
Prosopis juliflora (Meskit) pods as a major ingredient in a formulated
ration to provide an alternative non-conventional concentrate for
livestock feeding in Oman. Dry Meskit pods were reduced to lengths
of 0.5- 1.0 cm to ensure thorough mixing into three diets. Meskit
pods were subjected to two types of treatments; roasting and soaking.
They were roasted at 150оC for 30 minutes using a locally-made
roasting device (40 kg barrel container rotated by electric motor and
heated by flame gas cooker). Chopped pods were soaked in tap water
for 24 hours and dried for 2 days under the sun with frequent turning.
The Meskit-pod-based diets (MPBD) were formulated and pelleted
from 500 g/kg ground Meskit pods, 240 g/kg wheat bran, 200 g/kg
barley grain, 50 g/kg local dried sardines and 10 g/kg of salt. Twenty
four 10 months-old intact Omani male lambs with average body
weight of 27.3 kg (± 0.5 kg) were used in a feeding trial for 84 days.
They were divided (on body weight basis) and allocated to four diet
combination groups. These were: Rhodes grass hay (RGH) plus a
general ruminant concentrate (GRC); RGH plus raw Meskit pods
(RMP) based concentrate; RGH plus roasted Meskit pods (ROMP)
based concentrate; RGH plus soaked Meskit pods (SMP) based
concentrate Daily feed intakes and bi-weekly body weights were
recorded. MPBD had higher contents of crude protein (CP), acid
detergent fibre (ADF) and neutral detergent fibre (NDF) than the
GRC. Animals fed various types of MPBD did not show signs of ill
health. There was a significant effect of feeding ROMP on the
performance of Omani sheep compared to RMP and SMP. The
ROMP fed animals had similar performance to those fed the GRC in
terms of feed intake, body weight gain and feed conversion ratio
(FCR).This study indicated that roasted Meskit pods based diet may
be used instead of the commercial concentrate for feeding Omani
sheep without adverse effects on performance. It offers a cheap
alternative source of protein and energy for feeding Omani sheep.
Also, it might help in solving the spread impact of Meskit trees,
maintain the ecosystem and helping in preserving the local tree
species.
Abstract: Background and aim: It has not been well studied
whether fentanyl-thiopental (FT) is effective and safe for PSA in
orthopedic procedures in Emergency Department (ED). The aim of
this trial was to evaluate the effectiveness of intravenous FT versus
fentanyl-midazolam (FM) in patients who suffered from shoulder
dislocation or distal radial fracture-dislocation.
Methods: In this randomized double-blinded study, Seventy-six
eligible patients were entered the study and randomly received
intravenous FT or FM. The success rate, onset of action and recovery
time, pain score, physicians’ satisfaction and adverse events were
assessed and recorded by treating emergency physicians. The
statistical analysis was intention to treat.
Results: The success rate after administrating loading dose in FT
group was significantly higher than FM group (71.7% vs. 48.9%,
p=0.04); however, the ultimate unsuccessful rate after 3 doses of
drugs in the FT group was higher than the FM group (3 to 1) but it
did not reach to significant level (p=0.61). Despite near equal onset
of action time in two study group (P=0.464), the recovery period in
patients receiving FT was markedly shorter than FM group
(P
Abstract: Due to water shortage, application of saline water for
irrigation is an urgent in agriculture. In this study the effect of
calcium and potassium application as additive in saline root media for
reduce salinity adverse effects was investigated on tomato growth in
a hydroponic system with unequal distribution of salts in the root
media, which was divided in to two equal parts containing full
Johnson nutrient solution and 40 mMNaCl solution, alone or in
combination with KCl (6 mM), CaCl2 (4 mM), K+Ca (3+2 mM) or
half-strength Johnson nutrient solution. The root splits were
exchanged every 7 days. Results showed that addition of calcium,
calcium-potassium and nutrition elements equivalent to half the
concentration of Johnson formula to the saline-half of culture media
minimized the reduction in plant growth caused by NaCl, although
addition of potassium to culture media wasn’t effective. The greatest
concentration of sodium was observed at the shoot of treatments
which had smallest growth. According to the results of this study, in
case of dynamic and non-uniform distribution of salts in the root
media, by addition of additive to the saline solution, it would be
possible to use of saline water with no significant growth reduction.
Abstract: The presence of endocrine-disrupting compounds,
such as bisphenol A (BPA), in the environment can cause serious
health problems. However, there are controversial opinions. This
study investigated the reproductive, metabolic, oxidative and
immunologic-disrupting effects of bisphenol A in male rabbits.
Rabbits were divided into five groups. The first four rabbit groups
were administered oral BPA (1, 10, 50, or 100 mg/kg/day) for ten
weeks. The fifth group was administered corn oil as the vehicle. BPA
significantly decreased serum testosterone, estradiol and the free
androgen index (FAI) and significantly increased sex hormone
binding globulin (SHBG) compared with the placebo group. The
higher doses of BPA showed a significant decrease in follicular
stimulating hormone (FSH) and luteinizing hormone (LH). A
significant increase in blood glucose levels was identified in the BPA
groups. The non-significant difference in insulin levels is a novel
finding. The cumulative testicular toxicity of BPA was clearly
demonstrated by the dose-dependent decrease in absolute testes
weight, primary measures of semen quality and a significant increase
in testicular malonaldehyde (MDA). Moreover, BPA significantly
decreased total antioxidant capacity (TAC) and significantly
increased immunoglobulin G (IgG) at the highest concentration. Our
results suggest that BPA, especially at higher doses, is associated
with many adverse effects on metabolism, oxidative stress, immunity,
sperm quality and markers of androgenic action.
Abstract: The effects of soil inoculation with phosphorien-containing phosphate-dissolving bacteria (PDB) and/or magnesium (Mg) foliar application at the rates of 0, 0.5 and 1mM on growth, green pod and seed yields, and chemical constituents of Pisum sativum L. grown on a sandy calcareous soil were investigated. Results indicated that PDB and/or Mg significantly increased shoot length, number of branches plant–1, total leaf area plant–1 and canopy dry weight plant–1, leaf contents of pigments, soluble sugars, free proline, nitrogen, phosphorus, potassium, magnesium, and calcium, and Ca/Na ratio, while leaf Na content was reduced. PDB and/or Mg also increased green pod and seed yields. We concluded that PDB and Mg have pronounced positive effects on Pisum sativum L. plants grown on sandy calcareous soil. PDB and Mg, therefore, have the potential to be applied for various crops to overcome the adverse effects of the newly-reclaimed sandy calcareous soils.
Abstract: This paper aims to build a system based on fuzzy models that can be implemented in the assessment of ecological systems, to determine appropriate methods of action for reducing adverse effects on environmental and implicit the population. The model proposed provides new perspective for environmental assessment, and it can be used as a practical instrument for decision –making.
Abstract: Sustaining a desired rate of oxygen transfer for microbial activity is a matter of major concern for biological wastewater treatment (MBR). The study reported in the paper was aimed at assessing the effects of microbial products on the specific oxygen uptake rate (SOUR) in a conventional membrane bioreactor (CMBR) and that in a sponge submerged MBR (SSMBR). The production and progressive accumulation of soluble microbial products (SMP) and bound-extracellular polymeric substances (bEPS) were affecting the SOUR of the microorganisms which varied at different stages of operation of the MBR systems depending on the variable concentrations of the SMP/bEPS. The effect of bEPS on the SOUR was stronger in the SSMBR compared to that of the SMP, while relative high concentrations of SMP had adverse effects on the SOUR of the CMBR system. Of the different mathematical correlations analyzed in the study, logarithmic mathematical correlations could be established between SOUR and bEPS in SSMBR, and similar correlations could also be found between SOUR and SMP concentrations in the CMBR.
Abstract: Desurging tank with automatic air control “DTAAC” is a water hammer protection device, operates either an open or closed surge tank according to the water level inside the surge tank, with the volume of air trapped in the filling phase, this protection device has the advantages of its easy maintenance, and does not need to run any external energy source (air compressor). A computer program has been developed based on the characteristic method to simulate flow transient phenomena in pressurized water pipeline systems, it provides the influence of using the protection devices to control the adverse effects due to excessive and low pressure occurring in this phenomena. The developed model applied to a simple main water pipeline system: pump combined with DTAAC connected to a reservoir. The results obtained provide that the model is an efficient tool for water hammer analysis. Moreover; using the DTAAC reduces the unfavorable effects of the transients.
Abstract: The primary objectives of transient analysis are to determine the values of transient pressures that can result from flow control operations and to establish the design criteria for system equipment and devices (such as control devices and pipe wall thickness) so as to provide an acceptable level of protection against system failure due to pipe collapse or bursting. Because of the complexity of the equations needed to describe transients, numerical computer models are used to analyze transient flow hydraulics. An effective numerical model allows the hydraulic engineer to analyze potential transient events and to identify and evaluate alternative solutions for controlling hydraulic transients, thereby protecting the integrity of the hydraulic system. This paper presents the influence of using the protection devices to control the adverse effects due to excessive and low pressure occurs in the transient.
Abstract: Fluid transient analysis is one of the more challenging and complicated flow problems in the design and the operation of water pipeline systems (wps). When transient conditions "water hammer" exists, the life expectancy of the wps can be adversely impacted, resulting in pump and valve failures and catastrophic pipe ruptures. Transient control has become an essential requirement for ensuring safe operation of wps. An accurate analysis and suitable protection devices should be used to protect wps. This paper presents the problem of modeling and simulation of transient phenomena in wps based on the characteristics method. Also, it provides the influence of using the protection devices to control the adverse effects due to excessive and low pressure occur in the transient. The developed model applied for main wps: pump combined with closed surge tank connected to a reservoir. The results obtained provide that the model is an efficient tool for water hammer analysis. Moreover; using the closed surge tank reduces the unfavorable effects of transients.
Abstract: Upper gastrointestinal endoscopy is a commonly performed diagnostic and therapeutic procedure and has many adverse effects like cardiopulmonary complications, complications related to sedation, infectious complications, bleeding and perforation. So this study was undertaken to evaluate important variables like patient’s age, gender and stage of the procedure in relation to the cardiopulmonary changes during diagnostic upper gastrointestinal endoscopy by monitoring oxygen saturation, blood pressure, heart rate and electrocardiogram. This is a prospective longitudinal hospital based study involving a total of 140 consecutive patients, at Sri. B. M. Patil Medical College, Hospital and Research Centre. Cardiopulmonary changes during upper gastrointestinal endoscopy are more common in the age groups of 51-60 years, with equal frequency in both male and female. Oxygen saturation levels decreased by about 4% in both sexes during introduction of endoscopy. Mild to moderate hypoxia was found in 32% of the study group. Severe hypoxia was found in 5% of the patients, mostly in those patients who are above 50 years of age. Tachycardia was noted in 88% of the study group patients. Blood pressure increased to hypertension levels in 22 patients (15.7%) which returned to normal within few minutes after the procedure. S-T depression was noticed in 4% of patients and T wave inversion in 8% of patients during upper gastrointestinal endoscopy. All these changes disappeared after 10 minutes after the endoscopy. Cardiopulmonary changes are common during upper gastrointestinal endoscopy. Maximum changes in oxygen saturation, heart rate and blood pressure occurred immediately after the introduction of endoscope. The cardiopulmonary changes did not manifest into any identifiable clinical symptoms. The rate of recovery was faster in younger age groups and women.
Abstract: In this manuscript, we produced neat electrospun poly(o-methoxyaniline) (POMA) fibers and utilized it for applying the growth of neural stem cells. The transparency and morphology of as-prepared POMA fibers was characterized by UV-visible spectroscopy and scanning electron microscopy, respectively. It was found to have no adverse effects on the long-term proliferation of the neural stem cells (NSCs), retained the ability to self-renew, and exhibit multipotentiality. Results of immunofluorescence staining studies confirmed that POMA electrospun fibers could provide a great environment for NSCs and enhance its differentiation.
Abstract: The adverse effects of Clindamycin (Clind.) /
Ibuprofen (Ibu.) combination on liver, kidney, blood elements and the
significances of antioxidants (N-acetylcysteine and Zinc) against
these effects were evaluated. The study includes: Group I; control
n=30, Group II; patients on Clind.300mg/Ibu.400mg twice daily for a
week n=30, Group III; patients on Clind.300mg/Ibu.400mg+Nacetylcysteine
200mg twice daily for a week n=15 and Group IV;
patients on Clind.300mg/Ibu.400mg+Zinc50mg twice daily for a
week n=15. Serum malondialdehyde (MDA), alanine transferase
(ALT), aspartate transferase (AST), γ glutamyl transferase (GGT),
creatinine, blood urea nitrogen (BUN) were measured. Applying one
way ANOVA followed by Tuckey Kramer post test, Group II showed
significant increase in ALT, AST, GGT, BUN and decrease in Hb,
RBCs, platelets than Group I. Group III showed significant decrease
in ALT, AST, GGT, BUN than Group II. Moreover, Group IV
showed significant decrease in ALT, AST, GGT and increase in Hb,
RBCs, and platelets than Group II. Conclusively, Adding Zinc or Nacetylcysteine
buffer the oxidative stress and improve the therapeutic
outcome of Clindamycin/Ibuprofen combination.
Abstract: Dietary macro and micro nutrients in their respective proportion and fractions present a practical potential tool to fabricate milk constituents since cells of lactating mammary glands obtain about 80 % of milk synthesis nutrients from blood, reflecting the existence of an isotonic equilibrium between blood and milk. Diverting milk biosynthetic activities through manipulation of nutrients towards producing milk not only keeping in view its significance as natural food but also as food item which prevents or dilutes the adverse effects of some diseases (like cardiovascular problem by saturated milk fat intake) has been area of interest in the last decade. Nutritional modification / supplementation has been reported to enhance conjugated linoleic acid, fatty acid type and concentration, essential fatty acid concentration, vitamin B12& C, Se, Cu, I and Fe which are involved to counter the health threats to human well being. Synchronizing dietary nutrients aimed to modify rumen dynamics towards synthesis of nutrients or their precursors to make their drive towards formulated milk constituents presents a practical option. Formulating dietary constituents to design milk constituents will let the farmers, consumers and investors know about the real potential and profit margins associated with this enterprise. This article briefly recapitulates the ways and means to modify milk constituents keeping an eye on human health and well being issues, which allows milk to serve more than a food item.
Abstract: As a result of the high cost of housing, the increasing population is forced to live in substandard housing and unhealthy conditions giving rise to poor residential neighborhoods. The paper examines the causes and characteristics of poor residential neighborhood. The paper finds the problems that have influence poor neighborhoods to; poverty, growth of informal sector and housing shortage. The paper asserts that poor residential neighborhoods have adverse effects on the people.
The secondary data was obtained from books, journals and seminar papers while primary data relating to building and environmental quality from structured questionnaire administered on sample of 500 household heads, from sampling frame of 5000 housing units.
The study reveals that majority of the respondents are poor and employed in informal sector. The paper suggests urban renewal and slum upgrading programs as methods in dealing with the situation and an improvement in the socio-economic circumstances of the inhabitants.