Abstract: This paper considers various channels of gammaquantum
generation via an ultra-short high-power laser pulse
interaction with different targets.We analyse the possibilities to create
a pulsed gamma-radiation source using laser triggering of some
nuclear reactions and isomer targets. It is shown that sub-MeV
monochromatic short pulse of gamma-radiation can be obtained with
pulse energy of sub-mJ level from isomer target irradiated by intense
laser pulse. For nuclear reaction channel in light- atom materials, it is
shown that sub-PW laser pulse gives rise to formation about million
gamma-photons of multi-MeV energy.
Abstract: Modeling and simulation of biochemical reactions is of great interest in the context of system biology. The central dogma of this re-emerging area states that it is system dynamics and organizing principles of complex biological phenomena that give rise to functioning and function of cells. Cell functions, such as growth, division, differentiation and apoptosis are temporal processes, that can be understood if they are treated as dynamic systems. System biology focuses on an understanding of functional activity from a system-wide perspective and, consequently, it is defined by two hey questions: (i) how do the components within a cell interact, so as to bring about its structure and functioning? (ii) How do cells interact, so as to develop and maintain higher levels of organization and functions? In recent years, wet-lab biologists embraced mathematical modeling and simulation as two essential means toward answering the above questions. The credo of dynamics system theory is that the behavior of a biological system is given by the temporal evolution of its state. Our understanding of the time behavior of a biological system can be measured by the extent to which a simulation mimics the real behavior of that system. Deviations of a simulation indicate either limitations or errors in our knowledge. The aim of this paper is to summarize and review the main conceptual frameworks in which models of biochemical networks can be developed. In particular, we review the stochastic molecular modelling approaches, by reporting the principal conceptualizations suggested by A. A. Markov, P. Langevin, A. Fokker, M. Planck, D. T. Gillespie, N. G. van Kampfen, and recently by D. Wilkinson, O. Wolkenhauer, P. S. Jöberg and by the author.
Abstract: The equilibrium chemical reactions taken place in a converter reactor of the Khorasan Petrochemical Ammonia plant was studied using the minimization of Gibbs free energy method. In the minimization of the Gibbs free energy function the Davidon– Fletcher–Powell (DFP) optimization procedure using the penalty terms in the well-defined objective function was used. It should be noted that in the DFP procedure along with the corresponding penalty terms the Hessian matrices for the composition of constituents in the Converter reactor can be excluded. This, in fact, can be considered as the main advantage of the DFP optimization procedure. Also the effect of temperature and pressure on the equilibrium composition of the constituents was investigated. The results obtained in this work were compared with the data collected from the converter reactor of the Khorasan Petrochemical Ammonia plant. It was concluded that the results obtained from the method used in this work are in good agreement with the industrial data. Notably, the algorithm developed in this work, in spite of its simplicity, takes the advantage of short computation and convergence time.
Abstract: Bubble columns have a variety of applications in
absorption, bio-reactions, catalytic slurry reactions, and coal
liquefaction; because they are simple to operate, provide good heat
and mass transfer, having less operational cost. The use of
Computational Fluid Dynamics (CFD) for bubble column becomes
important, since it can describe the fluid hydrodynamics on both local
and global scale. Euler- Euler two-phase fluid model has been used to
simulate two-phase (air and water) transient up-flow in bubble
column (15cm diameter) using FLUENT6.3. These simulations and
experiments were operated over a range of superficial gas velocities
in the bubbly flow and churn turbulent regime (1 to16 cm/s) at
ambient conditions. Liquid velocity was varied from 0 to 16cm/s. The
turbulence in the liquid phase is described using the standard k-ε
model. The interactions between the two phases are described
through drag coefficient formulations (Schiller Neumann). The
objectives are to validate CFD simulations with experimental data,
and to obtain grid-independent numerical solutions. Quantitatively
good agreements are obtained between experimental data for hold-up
and simulation values. Axial liquid velocity profiles and gas holdup
profiles were also obtained for the simulation.
Abstract: Antimicrobial (AM) starch-based films were
developed by incorporating chitosan and lauric acid as antimicrobial
agent into starch-based film. Chitosan has wide range of applications
as a biomaterial, but barriers still exist to its broader use due to its
physical and chemical limitations. In this work, a series of
starch/chitosan (SC) blend films containing 8% of lauric acid was
prepared by casting method. The structure of the film was
characterized by Fourier transform infrared spectroscopy (FTIR), Xray
diffraction (XRD), and scanning electron microscopy (SEM).
The results indicated that there were strong interactions were present
between the hydroxyl groups of starch and the amino groups of
chitosan resulting in a good miscibility between starch and chitosan
in the blend films. Physical properties and optical properties of the
AM starch-based film were evaluated. The AM starch-based films
incorporated with chitosan and lauric acid showed an improvement in
water vapour transmission rate (WVTR) and addition of starch
content provided more transparent films while the yellowness of the
film attributed to the higher chitosan content. The improvement in
water barrier properties was mainly attributed to the hydrophobicity
of lauric acid and optimum chitosan or starch content. AM starch
based film also showed excellent oxygen barrier. Obtaining films
with good oxygen permeability would be an indication of the
potential use of these antimicrobial packaging as a natural packaging
and an alternative packaging to the synthetic polymer to protect food
from oxidation reactions
Abstract: This work presents the hydrogen production from
steam gasification of palm kernel shell (PKS) at 700 oC in the
presence of 5% Ni/BEA and 5% Fe/BEA as catalysts. The steam
gasification was performed in two-staged reactors to evaluate the
effect of calcinations temperature and the steam to biomass ratio on
the product gas composition. The catalytic activity of Ni/BEA
catalyst decreases with increasing calcinations temperatures from 500
to 700 oC. The highest H2 concentration is produced by Fe/BEA
(600) with more than 71 vol%. The catalytic activity of the catalysts
tested is found to correspond to its physicochemical properties. The
optimum range for steam to biomass ratio if found to be between 2 to
4. Excess steam content results in temperature drop in the gasifier
which is undesirable for the gasification reactions.
Abstract: This research project aims to investigate difference in
relative rates concerning phosphoryl transfer relevant to biological
catalysis of DNA and RNA in the pH-independent reactions.
Activated Models of DNA and RNA for alkyl-aryl phosphate diesters
(with 4-nitrophenyl as a good leaving group) have successfully been
prepared to gather kinetic parameters. Eyring plots for the pH–
independent hydrolysis of 1 and 2 were established at different
temperatures in the range 100–160 °C. These measurements have
been used to provide a better estimate for the difference in relative
rates between the reactivity of DNA and RNA cleavage. Eyring plot
gave an extrapolated rate of kH2O = 1 × 10-10 s -1 for 1 (RNA model)
and 2 (DNA model) at 25°C. Comparing the reactivity of RNA
model and DNA model shows that the difference in relative rates in
the pH-independent reactions is surprisingly very similar at 25°. This
allows us to obtain chemical insights into how biological catalysts
such as enzymes may have evolved to perform their current
functions.
Abstract: The chemistry of sulphone hydrazide has gained increase interest in both synthetic organic chemistry and biological fields and has considerable value. The therapeutic importance of these compounds is the attractive force to continue research in such a point. The present review covers the literature up to date for the synthesis, reactions and applications of such compounds.
Abstract: This study investigated possible ways to improve the
efficiency of the platinum precipitation process using ammonium
chloride by reducing the platinum content reporting to the effluent.
The ore treated consist of five platinum group metals namely,
ruthenium, rhodium, iridium, platinum, palladium and a precious
metal gold. Gold, ruthenium, rhodium and iridium were extracted
prior the platinum precipitation process. Temperature, reducing
agent, flow rate and potential difference were the variables controlled
to determine the operation conditions for optimum platinum
precipitation efficiency. Hydrogen peroxide was added as the
oxidizing agent at the temperature of 85-90oC and potential
difference of 700-850mV was the variable used to check the
oxidizing state of platinum. The platinum was further purified at
temperature between 60-65oC, potential difference above 700 mV,
ammonium chloride of 200 l, and at these conditions the platinum
content reporting to the effluent was reduced to less than 300ppm,
resulting in optimum platinum precipitation efficiency and purity of
99.9%.
Abstract: The major focus of this work was to characterize hydrodynamics in a packed-bed with and without static mixer by using Computational Fluid Dynamic (CFD). The commercial software: COMSOL MULTIPHYSICSTM Version 3.3 was used to simulate flow fields of mixed-gas reactants i.e. CO and H2. The packed-bed was a single tube with the inside diameter of 0.8 cm and the length of 1.2 cm. The static mixer was inserted inside the tube. The number of twisting elements was 1 with 0.8 cm in diameter and 1.2 cm in length. The packed-bed with and without static mixer were both packed with approximately 700 spherical structures representing catalyst pellets. Incompressible Navier-Stokes equations were used to model the gas flow inside the beds at steady state condition, in which the inlet Reynolds Number (Re) was 2.31. The results revealed that, with the insertion of static mixer, the gas was forced to flow radially inward and outward between the central portion of the tube and the tube wall. This could help improving the overall performance of the packed-bed, which could be utilized for heterogeneous catalytic reaction such as reforming and Fischer- Tropsch reactions.
Abstract: To understand working features of a micro combustor,
a computer code has been developed to study combustion of
hydrogen–air mixture in a series of chambers with same shape aspect
ratio but various dimensions from millimeter to micrometer level.
The prepared algorithm and the computer code are capable of
modeling mixture effects in different fluid flows including chemical
reactions, viscous and mass diffusion effects. The effect of various
heat transfer conditions at chamber wall, e.g. adiabatic wall, with
heat loss and heat conduction within the wall, on the combustion is
analyzed. These thermal conditions have strong effects on the
combustion especially when the chamber dimension goes smaller and
the ratio of surface area to volume becomes larger.
Both factors, such as larger heat loss through the chamber wall
and smaller chamber dimension size, may lead to the thermal
quenching of micro-scale combustion. Through such systematic
numerical analysis, a proper operation space for the micro-combustor
is suggested, which may be used as the guideline for microcombustor
design. In addition, the results reported in this paper
illustrate that the numerical simulation can be one of the most
powerful and beneficial tools for the micro-combustor design,
optimization and performance analysis.
Abstract: The current trend of increasing quality and demands
of the final product is affected by time analysis of the entire
manufacturing process. The primary requirement of manufacturing is
to produce as many products as soon as possible, at the lowest
possible cost, but of course with the highest quality. Such
requirements may be satisfied only if all the elements entering and
affecting the production cycle are in a fully functional condition.
These elements consist of sensory equipment and intelligent control
elements that are essential for building intelligent manufacturing
systems. The intelligent manufacturing paradigm includes a new
approach to production system structure design. Intelligent behaviors
are based on the monitoring of important parameters of system and
its environment. The flexible reaction to changes. The realization and
utilization of this design paradigm as an "intelligent manufacturing
system" enables the flexible system reaction to production
requirement as soon as environmental changes too. Results of these
flexible reactions are a smaller layout space, be decreasing of
production and investment costs and be increasing of productivity.
Intelligent manufacturing system itself should be a system that can
flexibly respond to changes in entering and exiting the process in
interaction with the surroundings.
Abstract: This paper discusses the causal explanation capability
of QRIOM, a tool aimed at supporting learning of organic chemistry
reactions. The development of the tool is based on the hybrid use of
Qualitative Reasoning (QR) technique and Qualitative Process
Theory (QPT) ontology. Our simulation combines symbolic,
qualitative description of relations with quantity analysis to generate
causal graphs. The pedagogy embedded in the simulator is to both
simulate and explain organic reactions. Qualitative reasoning through
a causal chain will be presented to explain the overall changes made
on the substrate; from initial substrate until the production of final
outputs. Several uses of the QPT modeling constructs in supporting
behavioral and causal explanation during run-time will also be
demonstrated. Explaining organic reactions through causal graph
trace can help improve the reasoning ability of learners in that their
conceptual understanding of the subject is nurtured.
Abstract: The paper presents an analytical solution for dispersion
of a solute in the peristaltic motion of a couple stress fluid
through a porous medium with slip condition in the presence of both
homogeneous and heterogeneous chemical reactions. The average
effective dispersion coefficient has been found using Taylor-s limiting
condition and long wavelength approximation. The effects of various
relevant parameters on the average coefficient of dispersion have been
studied. The average effective dispersion coefficient tends to increase
with permeability parameter but tends to decrease with homogeneous
chemical reaction rate parameter, couple stress parameter, slip parameter
and heterogeneous reaction rate parameter.
Abstract: This study describes a micro device integrated with
multi-chamber for polymerase chain reaction (PCR) with different
annealing temperatures. The device consists of the reaction
polydimethylsiloxane (PDMS) chip, a cover glass chip, and is
equipped with cartridge heaters, fans, and thermocouples for
temperature control. In this prototype, commercial software is utilized
to determine the geometric and operational parameters those are
responsible for creating the denaturation, annealing, and extension
temperatures within the chip. Two cartridge heaters are placed at two
sides of the chip and maintained at two different temperatures to
achieve a thermal gradient on the chip during the annealing step. The
temperatures on the chip surface are measured via an infrared imager.
Some thermocouples inserted into the reaction chambers are used to
obtain the transient temperature profiles of the reaction chambers
during several thermal cycles. The experimental temperatures
compared to the simulated results show a similar trend. This work
should be interesting to persons involved in the high-temperature
based reactions and genomics or cell analysis.
Abstract: Titanium oxide films with different morphologies have for the first time been fabricated through hydrothermal reactions between a titanium substrate and iodine powder in water or ethanol. SEM revealed that iodine supported titanium (Ti-I2) surface shows different morphologies with variable treatment conditions. The mean surface roughness (Ra) was increased in the different groups. Use of surfactant has a role to increase the roughness of the film. The surface roughness was in the range of 0.15 μm-0.42 μm. Furthermore, the electrochemical examinations showed that the Ti-I2 surface fabricated in alcoholic medium has high corrosion resistance than in aqueous medium.
Abstract: Sol-gel immobilization of enzymes, which can improve considerably their properties, is now one of the most used techniques. By deposition of the entrapped lipase on a solid support, a new and improved biocatalyst was obtained, which can be used with excellent results in acylation reactions. In this paper, lipase B from Candida antarctica was double immobilized on different adsorbents. These biocatalysts were employed in the kinetic resolution of several aliphatic secondary alcohols in organic medium. High total recovery yields of enzymatic activity, up to 560%, were obtained. For all the studied alcohols the enantiomeric ratios E were over 200. The influence of the reaction medium was studied for the kinetic resolution of 2-pentanol.
Abstract: The paper is concerned with the state examination as
well as the problems during the post surgical (orthopedic)
rehabilitation of the knee and ankle joint. An observation of the
current appliances for a passive rehabilitation devices is presented.
The major necessary and basic features of the intelligent
rehabilitation devices are considered. An approach for a new
intelligent appliance is suggested. The main advantages of the device
are: both active as well as passive rehabilitation of the patient based
on the human - patient reactions and a real time feedback. The basic
components: controller; electrical motor; encoder, force – torque
sensor are discussed in details. The main modes of operation of the
device are considered.
Abstract: To motivate users to adopt and use information
systems effectively, the nature of motivation should be carefully
investigated. People are usually motivated within ongoing processes
which include a chain of states such as perception, stimulation,
motivation, actions and reactions and finally, satisfaction. This study
assumes that the relevant motivation processes should be executed in
a proper and continuous manner to be able to persistently motivate
and re-motivate people in organizational settings and towards
information systems. On this basis, the study attempts to propose
possible relationships between this process-nature view of
motivation in terms of the common chain of states and the nearly
unique properties of information systems as is perceived by users in
the sense of a knowledgeable and authoritative entity. In the
conclusion section, some guidelines for practitioners are suggested to
ease their tasks for motivating people to adopt and use information
systems.
Abstract: The understanding of the system level of biological behavior and phenomenon variously needs some elements such as gene sequence, protein structure, gene functions and metabolic pathways. Challenging problems are representing, learning and reasoning about these biochemical reactions, gene and protein structure, genotype and relation between the phenotype, and expression system on those interactions. The goal of our work is to understand the behaviors of the interactions networks and to model their evolution in time and in space. We propose in this study an ontological meta-model for the knowledge representation of the genetic regulatory networks. Ontology in artificial intelligence means the fundamental categories and relations that provide a framework for knowledge models. Domain ontology's are now commonly used to enable heterogeneous information resources, such as knowledge-based systems, to communicate with each other. The interest of our model is to represent the spatial, temporal and spatio-temporal knowledge. We validated our propositions in the genetic regulatory network of the Aarbidosis thaliana flower