Abstract: Female breast cancer is the second in frequency after cervical cancer. Surgery is the most common treatment for breast cancer, followed by chemotherapy as a treatment of choice. Although effective, it causes serious side effects. Controlled-release drug delivery is an alternative method to improve the efficacy and safety of the treatment. It can release the dosage of drug between the minimum effect concentration (MEC) and minimum toxic concentration (MTC) within tumor tissue and reduce the damage of normal tissue and the side effect. Because an in vivo experiment of this system can be time-consuming and labor-intensive, a mathematical model is desired to study the effects of important parameters before the experiments are performed. Here, we describe a 3D mathematical model to predict the release of doxorubicin from pluronic gel to treat human breast cancer. This model can, ultimately, be used to effectively design the in vivo experiments.
Abstract: This paper presents a new algorithm for the channel estimation of the OFDM system based on a pilot signal for the new generation of high data rate communication systems. In orthogonal frequency division multiplexing (OFDM) systems over fast-varying fading channels, channel estimation and tracking is generally carried out by transmitting known pilot symbols in given positions of the frequency-time grid. In this paper, we propose to derive an improved algorithm based on the calculation of the mean and the variance of the adjacent pilot signals for a specific distribution of the pilot signals in the OFDM frequency-time grid then calculating of the entire unknown channel coefficients from the equation of the mean and the variance. Simulation results shows that the performance of the OFDM system increase as the length of the channel increase where the accuracy of the estimated channel will be increased using this low complexity algorithm, also the number of the pilot signal needed to be inserted in the OFDM signal will be reduced which lead to increase in the throughput of the signal over the OFDM system in compared with other type of the distribution such as Comb type and Block type channel estimation.
Abstract: The standard investigational method for obstructive
sleep apnea syndrome (OSAS) diagnosis is polysomnography (PSG),
which consists of a simultaneous, usually overnight recording of
multiple electro-physiological signals related to sleep and
wakefulness. This is an expensive, encumbering and not a readily
repeated protocol, and therefore there is need for simpler and easily
implemented screening and detection techniques. Identification of
apnea/hypopnea events in the screening recordings is the key factor
for the diagnosis of OSAS. The analysis of a solely single-lead
electrocardiographic (ECG) signal for OSAS diagnosis, which may
be done with portable devices, at patient-s home, is the challenge of
the last years. A novel artificial neural network (ANN) based
approach for feature extraction and automatic identification of
respiratory events in ECG signals is presented in this paper. A
nonlinear principal component analysis (NLPCA) method was
considered for feature extraction and support vector machine for
classification/recognition. An alternative representation of the
respiratory events by means of Kohonen type neural network is
discussed. Our prospective study was based on OSAS patients of the
Clinical Hospital of Pneumology from Iaşi, Romania, males and
females, as well as on non-OSAS investigated human subjects. Our
computed analysis includes a learning phase based on cross signal
PSG annotation.
Abstract: Malting is usually carried out on intact barley seed,
while hull is still attached to it. In this study, oat grain with and
without hull was subjected to controlled germination to optimize its
enzymes activity, in such a way that lipase has the lowest and α-
amylase and proteinase the highest activities. Since pH has a great
impact on the activity of the enzymes, the pH of germination media
was set up to 3 to 8. In dehulled oats, lipase and α-amylase had the
lowest and highest activities in pHs 3 and 6, respectively whereas the
highest proteinase activity was evidenced at pH 7 and 4 in the oats
with and without hull respectively. While measurements indicated
that the effect of hull on the enzyme activities particularly in lipase
and amylase at each level of the pH are significantly different, the
best results were obtained in those samples in which their hull had
been removed. However, since the similar lipase activity in
germinated dehulled oat were recorded at the pHs 4 and 5, therefore
it was concluded that pH 5 in dehulled oat seed may provide the
optimum enzyme activity for all the enzymes.
Abstract: Poly (ethylene glycol) (PEG) molecules attached to surfaces have shown high potential as a protein repellent due to their flexibility and highly water solubility. A quartz crystal microbalance recording frequency and dissipation changes (QCM-D) has been used to study the adsorption from aqueous solutions, of lysozyme and α-lactalbumin proteins (the last with and without calcium) onto modified stainless steel surfaces. Surfaces were coated with poly(ethylene imine) (PEI) and silicate before grafting on PEG molecules. Protein adsorption was also performed on the bare stainless steel surface as a control. All adsorptions were conducted at 23°C and pH 7.2. The results showed that the presence of PEG molecules significantly reduced the adsorption of lysozyme and α- lactalbumin (with calcium) onto the stainless steel surface. By contrast, and unexpected, PEG molecules enhanced the adsorption of α-lactalbumin (without calcium). It is suggested that the PEG -α- lactalbumin hydrophobic interaction plays a dominant role which leads to protein aggregation at the surface for this latter observation. The findings also lead to the general conclusion that PEG molecules are not a universal protein repellent. PEG-on-PEI surfaces were better at inhibiting the adsorption of lysozyme and α-lactalbumin (with calcium) than with PEG-on-silicate surfaces.
Abstract: This paper deals with new concept of using compressed atmospheric air as a zero pollution power source for running motorbikes. The motorbike is equipped with an air turbine in place of an internal combustion engine, and transforms the energy of the compressed air into shaft work. The mathematical modeling and performance evaluation of a small capacity compressed air driven vaned type novel air turbine is presented in this paper. The effect of isobaric admission and adiabatic expansion of high pressure air for different rotor to casing diameter ratios with respect to different vane angles (number of vanes) have been considered and analyzed. It is found that the shaft work output is optimum for some typical values of rotor / casing diameter ratios at a particular value of vane angle (no. of vanes). In this study, the maximum power is obtained as 4.5kW - 5.3kW (5.5-6.25 HP) when casing diameter is taken 100 mm, and rotor to casing diameter ratios are kept from 0.65 to 0.55. This value of output is sufficient to run motorbike.
Abstract: Discovering new biological knowledge from the highthroughput biological data is a major challenge to bioinformatics today. To address this challenge, we developed a new approach for protein classification. Proteins that are evolutionarily- and thereby functionally- related are said to belong to the same classification. Identifying protein classification is of fundamental importance to document the diversity of the known protein universe. It also provides a means to determine the functional roles of newly discovered protein sequences. Our goal is to predict the functional classification of novel protein sequences based on a set of features extracted from each protein sequence. The proposed technique used datasets extracted from the Structural Classification of Proteins (SCOP) database. A set of spectral domain features based on Fast Fourier Transform (FFT) is used. The proposed classifier uses multilayer back propagation (MLBP) neural network for protein classification. The maximum classification accuracy is about 91% when applying the classifier to the full four levels of the SCOP database. However, it reaches a maximum of 96% when limiting the classification to the family level. The classification results reveal that spectral domain contains information that can be used for classification with high accuracy. In addition, the results emphasize that sequence similarity measures are of great importance especially at the family level.
Abstract: This research project is developed in order to study
managerial styles of modern Thai executives. The thorough
understanding will lead to continuous improvement and efficient
performance of Thai business organizations. Regarding managerial
skills, Thai executives focus heavily upon human skills. Also, the
negotiator roles are most emphasis in their management. In addition,
Thai executives pay most attention to the fundamental management
principles including Harmony and Unity of Direction of the
organizations. Moreover, the management techniques, consisting of
Team work and Career Planning are of their main concern. Finally,
Thai executives wish to enhance their firms- image and employees-
morale through conducting the ethical and socially responsible
activities. The major tactic deployed to stimulate employees- ethical
behaviors and mindset is Code of Ethics development.
Abstract: Maize and Indian mustard are significant crops in
semi-arid climate zones of India. Improved water management
requires precise scheduling of irrigation, which in turn requires an
accurate computation of daily crop evapotranspiration (ETc). Daily
crop evapotranspiration comes as a product of reference
evapotranspiration (ET0) and the growth stage specific crop
coefficients modified for daily variation. The first objective of
present study is to develop crop coefficients Kc for Maize and Indian
mustard. The estimated values of Kc for maize at the four crop
growth stages (initial, development, mid-season, and late season) are
0.55, 1.08, 1.25, and 0.75, respectively, and for Indian mustard the Kc
values at the four growth stages are 0.3, 0.6, 1.12, and 0.35,
respectively. The second objective of the study is to compute daily
crop evapotranspiration from ET0 and crop coefficients. Average
daily ETc of maize varied from about 2.5 mm/d in the early growing
period to > 6.5 mm/d at mid season. The peak ETc of maize is 8.3
mm/d and it occurred 64 days after sowing at the reproductive growth
stage when leaf area index was 4.54. In the case of Indian mustard,
average ETc is 1 mm/d at the initial stage, >1.8 mm/d at mid season
and achieves a peak value of 2.12 mm/d on 56 days after sowing.
Improved schedules of irrigation have been simulated based on daily
crop evapo-transpiration and field measured data. Simulation shows a
close match between modeled and field moisture status prevalent
during crop season.
Abstract: This is a cross-cultural study that determines South
African multinational enterprises (MNEs) entry strategies as they
invest in Africa. An integrated theoretical framework comprising the
transaction cost theory, Uppsala model, eclectic paradigm and the
distance framework was adopted. A sample of 40 South African
MNEs with 415 existing FDI entries in Africa was drawn. Using an
ordered logistic regression model, the impact of culture on the choice
of degree of control by South African MNEs in Africa was
determined. Cultural distance was one of significant factors that
influenced South African MNEs- choice of degree of control.
Furthermore, South African MNEs are risk averse in all countries in
Africa but minimize the risks differently across sectors. Service
sectors chooses to own their subsidiaries 100% and avoid dealing
with the locals while manufacturing, resources and construction
choose to have a local partner to share the risk.
Abstract: The approach proposed here is oriented in the direction of fuzzy system for the analysis and the synthesis of intelligent climate controllers, the simulation of the internal climate of the greenhouse is achieved by a linear model whose coefficients are obtained by identification. The use of fuzzy logic controllers for the regulation of climate variables represents a powerful way to minimize the energy cost. Strategies of reduction and optimization are adopted to facilitate the tuning and to reduce the complexity of the controller.
Abstract: Renewed interest in propeller propulsion on aircraft
configurations combined with higher propeller loads lead to the question how the effects of the propulsion on model support disturbances
should be accounted for. In this paper, the determination of engine power effects on support interference of sting-mounted models is
demonstrated by a measurement on a four-engine turboprop aircraft.
CFD results on a more generic model are presented in order to clarify
the possible mechanism behind engine power effects on support
interference. The engine slipstream induces a local change in angle
of sideslip at the model sting thereby influencing the sting near-field and far-field effects. Whether or not the net result of these changes
in the disturbance pattern leads to a significant engine power effect depends on the configuration of the wind tunnel model and the test
setup.
Abstract: This paper presented two new efficient algorithms
for contour approximation. The proposed algorithm is compared
with Ramer (good quality), Triangle (faster) and Trapezoid (fastest)
in this work; which are briefly described. Cartesian co-ordinates of
an input contour are processed in such a manner that finally
contours is presented by a set of selected vertices of the edge of the
contour. In the paper the main idea of the analyzed procedures for
contour compression is performed. For comparison, the mean
square error and signal-to-noise ratio criterions are used.
Computational time of analyzed methods is estimated depending on
a number of numerical operations. Experimental results are
obtained both in terms of image quality, compression ratios, and
speed. The main advantages of the analyzed algorithm is small
numbers of the arithmetic operations compared to the existing
algorithms.
Abstract: This paper proposes the method combining artificial
neural network (ANN) with particle swarm optimization (PSO) to
implement the maximum power point tracking (MPPT) by controlling
the rotor speed of the wind generator. First, the measurements of wind
speed, rotor speed of wind power generator and output power of wind
power generator are applied to train artificial neural network and to
estimate the wind speed. Second, the method mentioned above is
applied to estimate and control the optimal rotor speed of the wind
turbine so as to output the maximum power. Finally, the result reveals
that the control system discussed in this paper extracts the maximum
output power of wind generator within the short duration even in the
conditions of wind speed and load impedance variation.
Abstract: In this paper an approaches for increasing the
effectiveness of error detection in computer network channels with
Pulse-Amplitude Modulation (PAM) has been proposed. Proposed
approaches are based on consideration of special feature of errors,
which are appearances in line with PAM. The first approach consists
of CRC modification specifically for line with PAM. The second
approach is base of weighted checksums using. The way for
checksum components coding has been developed. It has been shown
that proposed checksum modification ensure superior digital data
control transformation reliability for channels with PAM in compare
to CRC.
Abstract: This study was conducted to determine the
effect of abdominal exercises versus abdominal supporting
belt on abdominal efficiency and inter-recti separation
following vaginal delivery.30 primiparous post-natal women
participated in this study. Their age ranged from (25 - 35)
years and their BMI < 30 Kg/m2. Participants were assigned
randomly into 2groups, participants of group (A) used
abdominal belt from the 2nd day following delivery, till the end
of puerperium (6 weeks), while participants of group (B)
engaged into abdominal exercises program from the 2nd day
following delivery for 6 weeks. The results of the present
study revealed that although there was no statistical difference
in waist circumference between both groups, participation in
abdominal exercise program produced a pronounced reduction
in waist/hip ratio, and inter-recti separation and also caused
significant increase in abdominal muscles strength (peak
torque, maximum repetition total work and average power)
higher than the use of abdominal belt.
Abstract: The role of neighborhood center as semi public (the
balance space) is disappeared in bonding between private and public
in new urbanism. In this way, a hierarchical principle in the
traditional neighborhood center appears to create or develop the
conditions for residents` relationships and belonging. This paper
evaluates significant of hierarchical principles of the neighborhood
center in residents` territoriality and its factors. In this way Miandeh
neighborhood center from Boshrooyeh city was determined as a case
study area. Results indicated that a hierarchical principle is the best
instrument to improve the territoriality as the subcomponent of place
belonging in residents. The findings help the urban designer to
revitalization the neighborhoods and proceedings in organization of
physical space.
Abstract: Self-compacting concrete (SCC), a new kind of high
performance concrete (HPC) have been first developed in Japan in
1986. The development of SCC has made casting of dense
reinforcement and mass concrete convenient, has minimized noise.
Fresh self-compacting concrete (SCC) flows into formwork and
around obstructions under its own weight to fill it completely and
self-compact (without any need for vibration), without any
segregation and blocking. The elimination of the need for
compaction leads to better quality concrete and substantial
improvement of working conditions. SCC mixes generally have a
much higher content of fine fillers, including cement, and produce
excessively high compressive strength concrete, which restricts its
field of application to special concrete only. To use SCC mixes in
general concrete construction practice, requires low cost materials to
make inexpensive concrete.
Rice husk ash (RHA) has been used as a highly reactive
pozzolanic material to improve the microstructure of the interfacial
transition zone (ITZ) between the cement paste and the aggregate in
self compacting concrete. Mechanical experiments of RHA blended
Portland cement concretes revealed that in addition to the pozzolanic
reactivity of RHA (chemical aspect), the particle grading (physical
aspect) of cement and RHA mixtures also exerted significant
influences on the blending efficiency.
The scope of this research was to determine the usefulness of Rice
husk ash (RHA) in the development of economical self compacting
concrete (SCC). The cost of materials will be decreased by reducing
the cement content by using waste material like rice husk ash instead
of.
This paper presents a study on the development of Mechanical
properties up to 180 days of self compacting and ordinary concretes
with rice-husk ash (RHA), from a rice paddy milling industry in
Rasht (Iran). Two different replacement percentages of cement by
RHA, 10%, and 20%, and two different water/cementicious material
ratios (0.40 and 0.35), were used for both of self compacting and
normal concrete specimens. The results are compared with those of
the self compacting concrete without RHA, with compressive,
flexural strength and modulus of elasticity. It is concluded that RHA
provides a positive effect on the Mechanical properties at age after
60 days.
Base of the result self compacting concrete specimens have higher
value than normal concrete specimens in all test except modulus of
elasticity. Also specimens with 20% replacement of cement by RHA
have the best performance.
Abstract: This paper proposes a set of quasi-static mathematical
model of magnetic fields caused by high voltage conductors of
distribution transformer by using a set of second-order partial
differential equation. The modification for complex magnetic field
analysis and time-harmonic simulation are also utilized. In this
research, transformers were study in both balanced and unbalanced
loading conditions. Computer-based simulation utilizing the threedimensional
finite element method (3-D FEM) is exploited as a tool
for visualizing magnetic fields distribution volume a distribution
transformer. Finite Element Method (FEM) is one among popular
numerical methods that is able to handle problem complexity in
various forms. At present, the FEM has been widely applied in most
engineering fields. Even for problems of magnetic field distribution,
the FEM is able to estimate solutions of Maxwell-s equations
governing the power transmission systems. The computer simulation
based on the use of the FEM has been developed in MATLAB
programming environment.
Abstract: This study examines causal link between energy use and economic growth for five South Asian countries over period 1971-2006. Panel cointegration, ECM and FMOLS are applied for short and long run estimates. In short run unidirectional causality from per capita GDP to per capita energy consumption is found, but not vice versa. In long run one percent increase in per capita energy consumption tend to decrease 0.13 percent per capita GDP. i.e. Energy use discourage economic growth. This short and long run relationship indicate energy shortage crisis in South Asia due to increased energy use coupled with insufficient energy supply. Beside this long run estimated coefficient of error term suggest that short term adjustment to equilibrium are driven by adjustment back to long run equilibrium. Moreover, per capita energy consumption is responsive to adjustment back to equilibrium and it takes 59 years approximately. It specifies long run feedback between both variables.