Abstract: In this investigation, we have evaluated the effects of
arsenic trioxide on hepatic function in pregnant and lactating Swiss
albino mice and their suckling pups. Experiments were carried out on
female mice given 175 ppm As2O3 in their drinking water from the
14th day of pregnancy until day 14 after delivery. Our results showed
a significant decrease in plasma levels of total protein and albumin,
cholesterol and triglyceride in As2O3 treated mice and their pups. The
hyperbilirubinemia and the increased plasma total alkaline
phosphatase activity suggested the presence of cholestasis.
Transaminase activities as well as lactate deshydrogenase activity in
plasma, known as biomarkers of hepatocellular injury, were elevated
indicating hepatic cells’ damage after treatment with As2O3.
Exposure to arsenic led to an increase of liver thiobarbituric acid
reactive substances level along with a concomitant decrease in the
activities of superoxide dismutase, catalase and glutathione
peroxidase and in glutathione.
Abstract: Near-infrared spectroscopy (NIRS) has been widely
used as a non-invasive method to measure brain activity, but it is
corrupted by baseline drift noise. Here we present a method to measure
regional cerebral blood flow as a derivative of NIRS output. We
investigate whether, when listening to languages, blood flow can
reasonably localize and represent regional brain activity or not. The
prefrontal blood flow distribution pattern when advanced
second-language listeners listened to a second language (L2) was most
similar to that when listening to their first language (L1) among the
patterns of mean and standard deviation. In experiments with 25
healthy subjects, the maximum blood flow was localized to the left
BA46 of advanced listeners. The blood flow presented is robust to
baseline drift and stably localizes regional brain activity.
Abstract: The aim of this paper is to perform experimental
modal analysis (EMA) of reinforced concrete (RC) square slabs.
EMA is the process of determining the modal parameters (Natural
Frequencies, damping factors, modal vectors) of a structure from a
set of frequency response functions FRFs (curve fitting). Although,
experimental modal analysis (or modal testing) has grown steadily in
popularity since the advent of the digital FFT spectrum analyzer in
the early 1970’s, studying all types of members and materials using
such method have not yet been well documented. Therefore, in this
work, experimental tests were conducted on RC square slab
specimens of dimensions 600mm x 600mmx 40mm. Experimental
analysis was based on freely supported boundary condition.
Moreover, impact testing as a fast and economical means of finding
the modes of vibration of a structure was used during the
experiments. In addition, Pico Scope 6 device and MATLAB
software were used to acquire data, analyze and plot Frequency
Response Function (FRF). The experimental natural frequencies
which were extracted from measurements exhibit good agreement
with analytical predictions. It is showed that EMA method can be
usefully employed to investigate the dynamic behavior of RC slabs.
Abstract: Cell volume, together with membrane potential and
intracellular hydrogen ion concentration, is an essential biophysical
parameter for normal cellular activity. Cell volumes can be altered by
osmotically active compounds and extracellular tonicity.
In this study, a simple mathematical model of osmotically induced
cell swelling and shrinking is presented. Emphasis is given to water
diffusion across the membrane. The mathematical description of the
cellular behavior consists in a system of coupled ordinary differential
equations. We compare experimental data of cell volume alterations
driven by differences in osmotic pressure with mathematical
simulations under hypotonic and hypertonic conditions. Implications
for a future model are also discussed.
Abstract: To achieve reliable welds with minimum distortion for
the fabrication of components in aerospace industry laser beam
welding is attempted. Laser welding can provide a significant benefit
for the welding of Titanium and Aluminium thin sheet alloys of its
precision and rapid processing capability. For laser welding, pulse
shape, energy, duration, repetition rate and peak power are the most
important parameters that influence directly the quality of welds. In
this experimental work for joining 1mm thick TI6AL4V and AA2024
alloy and JK600 Nd:YAG pulsed laser units used. The distortions at
different welding power and speed of titanium and aluminium thin
sheet alloys are investigated. Test results reveal that increase in
welding speed increases distortion in weldment
Abstract: The practice of freeing monuments from subsequent
additions crosses the entire history of conservation and it is
traditionally connected to the aim of valorisation, both for cultural
and educational purpose and recently even for touristic exploitation.
Defence heritage has been widely interested by these cultural and
technical moods from philological restoration to critic innovations. A
renovated critical analysis of Italian episodes and in particular the
Sardinian case of the area of San Pancrazio in Cagliari, constitute an
important lesson about the limits of this practice and the uncertainty
in terms of results, towards the definition of a sustainable good
practice in the restoration of military architectures.
Abstract: Social Media (SM) is websites increasingly popular
and built to allow people to express themselves and to interact
socially with others. Most SMT are dominated by youth particularly
College students. The proliferation of popular social media tools,
which can accessed from any communication devices has become
pervasive in the lives of today’s student life. Connecting traditional
education to social media tools are a relatively new era and any
collaborative tool could be used for learning activities. This study
focuses (i) how the social media tools are useful for the learning
activities of the students of faculty of medicine in King Khalid
University (ii) whether the social media affects the collaborative
learning with interaction among students, among course instructor,
their engagement, perceived ease of use and perceived ease of
usefulness (TAM) (iii) overall, the students satisfy with this
collaborative learning through Social media.
Abstract: Graphical User Interface (GUI) is essential to
programming, as is any other characteristic or feature, due to the fact
that GUI components provide the fundamental interaction between
the user and the program. Thus, we must give more interest to GUI
during building and development of systems. Also, we must give a
greater attention to the user who is the basic corner in the dealing
with the GUI. This paper introduces an approach for designing GUI
from one of the models of business workflows which describe the
workflow behavior of a system, specifically through Activity
Diagrams (AD).
Abstract: As the use of geothermal energy grows internationally
more effort is required to monitor and protect areas with rare and
important geothermal surface features. A number of approaches are
presented for developing and calibrating numerical geothermal
reservoir models that are capable of accurately representing
geothermal surface features. The approaches are discussed in the
context of cases studies of the Rotorua geothermal system and the
Orakei-korako geothermal system, both of which contain important
surface features. The results show that models are able to match the
available field data accurately and hence can be used as valuable
tools for predicting the future response of the systems to changes in
use.
Abstract: Although, arsenic trioxide has been the subject of
toxicological research, in vitro cytotoxicity and genotoxicity studies
using relevant cell models and uniform methodology are not well
elucidated. Hence, the aim of the present study was to evaluate the
cytotoxicity and genotoxicity induced by arsenic trioxide in human
keratinocytes (HaCaT) using the MTT [3-(4, 5-dimethylthiazol-2-yl)-
2,5-diphenyltetrazolium bromide] and alkaline single cell gel
electrophoresis (Comet) assays, respectively. Human keratinocytes
were treated with different doses of arsenic trioxide for 4 h prior to
cytogenetic assessment. Data obtained from the MTT assay indicated
that arsenic trioxide significantly reduced the viability of HaCaT cells
in a dose-dependent manner, showing an IC50 value of 34.18 ± 0.6
μM. Data generated from the comet assay also indicated a significant
dose-dependent increase in DNA damage in HaCaT cells associated
with arsenic trioxide exposure. We observed a significant increase in
comet tail length and tail moment, showing an evidence of arsenic
trioxide -induced genotoxic damage in HaCaT cells. This study
confirms that the comet assay is a sensitive and effective method to
detect DNA damage caused by arsenic.
Abstract: Generally the natural environment is made up of air,
water and soil. The release of emission of industrial waste into
anyone of the components of the environment causes pollution.
Industrial pollution significantly threatens the inherent right of
people, to the enjoyment of a safe and secure environment. The aim
of this paper is to assess the effect of environmental pollution and
health risks of residents living near Ewekoro cement factory. The
research made use of IKONOS imagery for Geographical
Information System (GIS) to buffer and extract buildings that are less
than 1km to the factory, within 1km to 5km and above 5km to the
factory. Also questionnaire was used to elicit information on the
socio-economic factors, effect of environmental pollution on
residents and measures adopted to control industrial pollution on the
residents. Findings show that most buildings that fall between less
than 1km and 1km to 5km to the factory have high health risk in the
study area. The study recommended total relocation for the residents
of the study area to reduce health risk problems.
Abstract: An investigation into Cahn-Hilliard equation was
carried out through numerical simulation to identify a possible phase
separation for one and two dimensional domains. It was observed that
this equation can reproduce important mass fluxes necessary for
phase separation within the miscibility gap and for coalescence of
particles.
Abstract: This paper presents small signal stability study carried
over the 140-Bus, 31-Machine, 5-Area MEPE system and validated
on free and open source software: PSAT. Well-established linearalgebra
analysis, eigenvalue analysis, is employed to determine the
small signal dynamic behavior of test system. The aspects of local
and interarea oscillations which may affect the operation and
behavior of power system are analyzed. Eigenvalue analysis is carried
out to investigate the small signal behavior of test system and the
participation factors have been determined to identify the
participation of the states in the variation of different mode shapes.
Also, the variations in oscillatory modes are presented to observe the
damping performance of the test system.
Abstract: Random epistemologies and hash tables have garnered
minimal interest from both security experts and experts in the last
several years. In fact, few information theorists would disagree with
the evaluation of expert systems. In our research, we discover how
flip-flop gates can be applied to the study of superpages. Though
such a hypothesis at first glance seems perverse, it is derived from
known results.
Abstract: For the treatment of acute and chronic lung diseases it is preferred to deliver medicaments by inhalation. The drug is delivered directly to tracheobronchial tree. This way allows the given medicament to get directly into the place of action and it makes rapid onset of action and maximum efficiency. The transport of aerosol particles in the particular part of the lung is influenced by their size, anatomy of the lungs, breathing pattern and airway resistance. This article deals with calculation of airway resistance in the lung model of Horsfield. It solves the problem of determination of the pressure losses in bifurcation and thus defines the pressure drop at a given location in the bronchial tree. The obtained data will be used as boundary conditions for transport of aerosol particles in a central part of bronchial tree realized by Computational Fluid Dynamics (CFD) approach. The results obtained from CFD simulation will allow us to provide information on the required particle size and optimal inhalation technique for particle transport into particular part of the lung.
Abstract: Elastomeric dielectric material has recently become a
new alternative for actuator technology. The characteristics of
dielectric elastomers placed between two electrodes to withstand
large strain when electrodes are charged has attracted the attention of
many researcher to study this material for actuator technology. Thus,
in the past few years Danfoss Ventures A/S has established their own
dielectric electro-active polymer (DEAP), which was called
PolyPower.
The main objective of this work was to investigate the dynamic
characteristics for vibration control of a PolyPower actuator folded in
‘pull’ configuration. A range of experiments was carried out on the
folded actuator including passive (without electrical load) and active
(with electrical load) testing. For both categories static and dynamic
testing have been done to determine the behavior of folded DEAP
actuator.
Voltage-Strain experiments show that the DEAP folded actuator is
a non-linear system. It is also shown that the voltage supplied has no
effect on the natural frequency. Finally, varying AC voltage with
different amplitude and frequency shows the parameters that
influence the performance of DEAP folded actuator. As a result, the
actuator performance dominated by the frequency dependence of the
elastic response and was less influenced by dielectric properties.
Abstract: The 3D body movement signals captured during
human-human conversation include clues not only to the content of
people’s communication but also to their culture and personality.
This paper is concerned with automatic extraction of this information
from body movement signals. For the purpose of this research, we
collected a novel corpus from 27 subjects, arranged them into groups
according to their culture. We arranged each group into pairs and
each pair communicated with each other about different topics.
A state-of-art recognition system is applied to the problems of
person, culture, and topic recognition. We borrowed modeling,
classification, and normalization techniques from speech recognition.
We used Gaussian Mixture Modeling (GMM) as the main technique
for building our three systems, obtaining 77.78%, 55.47%, and
39.06% from the person, culture, and topic recognition systems
respectively. In addition, we combined the above GMM systems with
Support Vector Machines (SVM) to obtain 85.42%, 62.50%, and
40.63% accuracy for person, culture, and topic recognition
respectively.
Although direct comparison among these three recognition
systems is difficult, it seems that our person recognition system
performs best for both GMM and GMM-SVM, suggesting that intersubject
differences (i.e. subject’s personality traits) are a major
source of variation. When removing these traits from culture and
topic recognition systems using the Nuisance Attribute Projection
(NAP) and the Intersession Variability Compensation (ISVC)
techniques, we obtained 73.44% and 46.09% accuracy from culture
and topic recognition systems respectively.
Abstract: Speech Segmentation is the measure of the change
point detection for partitioning an input speech signal into regions
each of which accords to only one speaker. In this paper, we apply
two features based on multi-scale product (MP) of the clean speech,
namely the spectral centroid of MP, and the zero crossings rate of
MP. We focus on multi-scale product analysis as an important tool
for segmentation extraction. The MP is based on making the product
of the speech wavelet transform coefficients (WTC). We have
estimated our method on the Keele database. The results show the
effectiveness of our method. It indicates that the two features can find
word boundaries, and extracted the segments of the clean speech.
Abstract: Arising problems of countries’ public finances, social
and demographic changes motivate scientific and policy debates on
public spending size, structure and efficiency in order to meet the
changing needs of society and business. The concept of sustainable
development poses new challenges for scientists and policy-makers
in the field of public finance. This paper focuses on the investigation
of the relationship between government expenditure and country’s
economic development in the context of sustainable development.
Empirical analysis focuses on the data of the European Union (except
Croatia and Luxemburg) countries. The study covers 2003 – 2012
years, using annual cross-sectional data. Summarizing the research
results, it can be stated that governments should pay more attention to
the needs that ensure sustainable development in the long-run when
formulating public expenditure policy, particularly in the field of
environment protection.
Abstract: Recently, universities are increasingly consuming
energy to support various activities. A large population of staff and
students in Malaysian universities has led to excessive energy
consumption which directly gives an impact to the environment. The
key question then ascended “How well is an energy management
(EM) been practiced in universities without taking the Critical
Success Factors (CSFs) into consideration to ensure the management
of university achieves the goals in reducing energy consumption.
Review on past literature is carried out to establish CSFs for EM best
practices. Thus, this paper highlighted the CSFs which have to be
focused on by management of university to successfully measure the
EM implementation and its performance. At the end of this paper, a
theoretical framework is developed for EM success factors towards
sustainable university.