Abstract: Real bronchial tree is very complicated piping system.
Analysis of flow and pressure losses in this system is very difficult.
Due to the complex geometry and the very small size in the lower
generations is examination by CFD possible only in the central part
of bronchial tree. For specify the pressure losses of lower generations
is necessary to provide a mathematical equation. Determination of
mathematical formulas for calculation of pressure losses in the real
lungs is time consuming and inefficient process due to its complexity
and diversity. For these calculations is necessary to slightly simplify
the geometry of lungs (same cross-section over the length of
individual generation) or use one of the idealized models of lungs
(Horsfield, Weibel). The article compares the values of pressure
losses obtained from CFD simulation of air flow in the central part of
the real bronchial tree with the values calculated in a slightly
simplified real lungs by using a mathematical relationship derived
from the Bernoulli and continuity equations. The aim of the article is
to analyse the accuracy of the analytical method and its possibility of
use for the calculation of pressure losses in lower generations, which
is difficult to solve by numerical method due to the small geometry.
Abstract: For the treatment of acute and chronic lung diseases it is preferred to deliver medicaments by inhalation. The drug is delivered directly to tracheobronchial tree. This way allows the given medicament to get directly into the place of action and it makes rapid onset of action and maximum efficiency. The transport of aerosol particles in the particular part of the lung is influenced by their size, anatomy of the lungs, breathing pattern and airway resistance. This article deals with calculation of airway resistance in the lung model of Horsfield. It solves the problem of determination of the pressure losses in bifurcation and thus defines the pressure drop at a given location in the bronchial tree. The obtained data will be used as boundary conditions for transport of aerosol particles in a central part of bronchial tree realized by Computational Fluid Dynamics (CFD) approach. The results obtained from CFD simulation will allow us to provide information on the required particle size and optimal inhalation technique for particle transport into particular part of the lung.
Abstract: A game for training of breath (TRABR) for continuous
monitoring of pulmonary ventilation during the patients’ therapy
focuses especially on monitoring of their ventilation processes. It is
necessary to detect, monitor and differentiate abdominal and thoracic
breathing during the therapy. It is a fun form of rehabilitation where
the patient plays and also practicing isolated breathing. Finally the
game to practice breath was designed to evaluate whether the patient
uses two types of breathing or not.
Abstract: A polypropylene hollow fiber membrane module is used for separating dissolved gases which contain dissolved oxygen from water. These dissolved gases can be used for underwater breathing. To be used for a human, the minimum amount of oxygen is essential. To increase separation of dissolved gases, much water and high surface area of hollow fibers are requested. For efficient separation system, performance of single membrane module with high surface area needs to be investigated.
In this study, we set up experimental devices for analyzing separation characteristics of dissolved gases including oxygen from water using a polypropylene hollow fiber membrane module. Separation of dissolved gases from water is investigated with variations of water flow rates. Composition of dissolved gases is also measured using GC. These results expect to be used in developing the portable separation system.
Abstract: The study deals with the modelling of the gas flow during heliox therapy. A special model has been developed to study the effect of the helium upon the gas flow in the airways during the spontaneous breathing. Lower density of helium compared with air decreases the Reynolds number and it allows improving the flow during the spontaneous breathing. In the cases, where the flow becomes turbulent while the patient inspires air the flow is still laminar when the patient inspires heliox. The use of heliox decreases the work of breathing and improves ventilation. It allows in some cases to prevent the intubation of the patients.