Abstract: Quantitative analyses of whisker movements provide a
means to study functional recovery and regeneration of mouse facial
nerve after an injury. However, accurate tracking of the mouse whisker
movement is challenging. Most methods for whisker tracking require
manual intervention, e.g. fixing the head of the mouse during a study.
Here we describe a semi-automated image processing method, which
is applied to high-speed video recordings of free-moving mice to track
the whisker movements. We first track the head movement of a mouse
by delineating the lower head contour frame-by-frame that allows for
detection of the location and orientation of the head. Then, a region of
interest is identified for each frame; the subsequent application of a
mask and the Hough transform detects the selected whiskers on each
side of the head. Our approach is used to examine the functional
recovery of damaged facial nerves in mice over a course of 21 days.
Abstract: Purpose: The study aimed to assess the depressant or
antidepressant effects of several Nonsteroidal Anti-Inflammatory
Drugs (NSAIDs) in mice: the selective cyclooxygenase-2 (COX-2)
inhibitor meloxicam, and the non-selective COX-1 and COX-2
inhibitors lornoxicam, sodium metamizole, and ketorolac. The
current literature data regarding such effects of these agents are
scarce.
Materials and methods: The study was carried out on NMRI mice
weighing 20-35 g, kept in a standard laboratory environment. The
study was approved by the Ethics Committee of the University of
Medicine and Pharmacy „Carol Davila”, Bucharest. The study agents
were injected intraperitoneally, 10 mL/kg body weight (bw) 1 hour
before the assessment of the locomotor activity by cage testing (n=10
mice/ group) and 2 hours before the forced swimming tests (n=15).
The study agents were dissolved in normal saline (meloxicam,
sodium metamizole), ethanol 11.8% v/v in normal saline (ketorolac),
or water (lornoxicam), respectively. Negative and positive control
agents were also given (amitryptilline in the forced swimming test).
The cage floor used in the locomotor activity assessment was divided
into 20 equal 10 cm squares. The forced swimming test involved
partial immersion of the mice in cylinders (15/9cm height/diameter)
filled with water (10 cm depth at 28C), where they were left for 6
minutes. The cage endpoint used in the locomotor activity assessment
was the number of treaded squares. Four endpoints were used in the
forced swimming test (immobility latency for the entire 6 minutes,
and immobility, swimming, and climbing scores for the final 4
minutes of the swimming session), recorded by an observer that was
„blinded” to the experimental design. The statistical analysis used the
Levene test for variance homogeneity, ANOVA and post-hoc
analysis as appropriate, Tukey or Tamhane tests.
Results: No statistically significant increase or decrease in the
number of treaded squares was seen in the locomotor activity
assessment of any mice group. In the forced swimming test,
amitryptilline showed an antidepressant effect in each experiment, at
the 10 mg/kg bw dosage. Sodium metamizole was depressant at 100
mg/kg bw (increased the immobility score, p=0.049, Tamhane test),
but not in lower dosages as well (25 and 50 mg/kg bw). Ketorolac
showed an antidepressant effect at the intermediate dosage of 5
mg/kg bw, but not so in the dosages of 2.5 and 10 mg/kg bw,
respectively (increased the swimming score, p=0.012, Tamhane test).
Meloxicam and lornoxicam did not alter the forced swimming
endpoints at any dosage level.
Discussion: 1) Certain NSAIDs caused changes in the forced
swimming patterns without interfering with locomotion. 2) Sodium
metamizole showed a depressant effect, whereas ketorolac proved
antidepressant. Conclusion: NSAID-induced mood changes are not
class effects of these agents and apparently are independent of the
type of inhibited cyclooxygenase (COX-1 or COX-2).
Disclosure: This paper was co-financed from the European Social
Fund, through the Sectorial Operational Programme Human Resources Development 2007-2013, project number POSDRU /159
/1.5 /S /138907 "Excellence in scientific interdisciplinary research,
doctoral and postdoctoral, in the economic, social and medical fields
-EXCELIS", coordinator The Bucharest University of Economic
Studies.
Abstract: The aim of this paper is to present the concept of an
agile enterprise model and to initiate discussion on the research
assumptions of the model presented. The implementation of the
research project "The agility of enterprises in the process of adapting
to the environment and its changes" began in August 2014 and is
planned to last three years. The article has the form of a work-inprogress
paper which aims to verify and initiate a debate over the
proposed research model. In the literature there are very few
publications relating to research into agility; it can be concluded that
the most controversial issue in this regard is the method of measuring
agility. In previous studies the operationalization of agility was often
fragmentary, focusing only on selected areas of agility, for example
manufacturing, or analysing only selected sectors. As a result the
measures created to date can only be treated as contributory to the
development of precise measurement tools. This research project
aims to fill a cognitive gap in the literature with regard to the
conceptualization and operationalization of an agile company. Thus,
the original contribution of the author of this project is the
construction of a theoretical model that integrates manufacturing
agility (consisting mainly in adaptation to the environment) and
strategic agility (based on proactive measures). The author of this
research project is primarily interested in the attributes of an agile
enterprise which indicate that the company is able to rapidly adapt to
changing circumstances and behave pro-actively.
Abstract: Edge is variation of brightness in an image. Edge
detection is useful in many application areas such as finding forests,
rivers from a satellite image, detecting broken bone in a medical
image etc. The paper discusses about finding edge of multiple aerial
images in parallel. The proposed work tested on 38 images 37
colored and one monochrome image. The time taken to process N
images in parallel is equivalent to time taken to process 1 image in
sequential. Message Passing Interface (MPI) and Open Computing
Language (OpenCL) is used to achieve task and pixel level
parallelism respectively.
Abstract: Kidney cancer is the most lethal urological cancer
accounting for 3% of adult malignancies. VHL, a tumor-suppressor
gene, is best known to be associated with renal cell carcinoma
(RCC). The VHL functions as negative regulator of hypoxia inducible
factors. Recent sequencing efforts have identified several novel
frequent mutations of histone modifying and chromatin remodeling
genes in ccRCC (clear cell RCC) including PBRM1 and SETD2. The
PBRM1 gene encodes the BAF180 protein, which involved in
transcriptional activation and repression of selected genes. SETD2
encodes a histone methyltransferase, which may play a role in
suppressing tumor development. In this study, RNAs of 30 paired
tumor and normal samples that were grouped according to the types
of kidney cancer and clinical characteristics of patients, including
gender and average age were examined by RT-PCR, SSCP and
sequencing techniques. VHL, PBRM1 and SETD2 expressions were
relatively down-regulated. However, statistically no significance was
found (Wilcoxon signed rank test, p>0.05). Interestingly, no mutation
was observed on the contrary of previous studies. Understanding the
molecular mechanisms involved in the pathogenesis of RCC has
aided the development of molecular-targeted drugs for kidney cancer.
Further analysis is required to identify the responsible genes rather
than VHL, PBRM1 and SETD2 in kidney cancer.
Abstract: The problems arising from unbalanced data sets
generally appear in real world applications. Due to unequal class
distribution, many researchers have found that the performance of
existing classifiers tends to be biased towards the majority class. The
k-nearest neighbors’ nonparametric discriminant analysis is a method
that was proposed for classifying unbalanced classes with good
performance. In this study, the methods of discriminant analysis are
of interest in investigating misclassification error rates for classimbalanced
data of three diabetes risk groups. The purpose of this
study was to compare the classification performance between
parametric discriminant analysis and nonparametric discriminant
analysis in a three-class classification of class-imbalanced data of
diabetes risk groups. Data from a project maintaining healthy
conditions for 599 employees of a government hospital in Bangkok
were obtained for the classification problem. The employees were
divided into three diabetes risk groups: non-risk (90%), risk (5%),
and diabetic (5%). The original data including the variables of
diabetes risk group, age, gender, blood glucose, and BMI were
analyzed and bootstrapped for 50 and 100 samples, 599 observations
per sample, for additional estimation of the misclassification error
rate. Each data set was explored for the departure of multivariate
normality and the equality of covariance matrices of the three risk
groups. Both the original data and the bootstrap samples showed nonnormality
and unequal covariance matrices. The parametric linear
discriminant function, quadratic discriminant function, and the
nonparametric k-nearest neighbors’ discriminant function were
performed over 50 and 100 bootstrap samples and applied to the
original data. Searching the optimal classification rule, the choices of
prior probabilities were set up for both equal proportions (0.33: 0.33:
0.33) and unequal proportions of (0.90:0.05:0.05), (0.80: 0.10: 0.10)
and (0.70, 0.15, 0.15). The results from 50 and 100 bootstrap samples
indicated that the k-nearest neighbors approach when k=3 or k=4 and
the defined prior probabilities of non-risk: risk: diabetic as 0.90:
0.05:0.05 or 0.80:0.10:0.10 gave the smallest error rate of
misclassification. The k-nearest neighbors approach would be
suggested for classifying a three-class-imbalanced data of diabetes
risk groups.
Abstract: Networking is important among students to achieve
better understanding. Social networking plays an important role in the
education. Realizing its huge potential, various organizations,
including institutions of higher learning have moved to the area of
social networks to interact with their students especially through
Facebook. Therefore, measuring the effectiveness of Facebook as a
learning tool has become an area of interest to academicians and
researchers. Therefore, this study tried to integrate and propose new
theoretical and empirical evidences by linking the western idea of
adopting Facebook as an alternative learning platform from a
Malaysian perspective. This study, thus, aimed to fill a gap by being
among the pioneering research that tries to study the effectiveness of
adopting Facebook as a learning platform across other cultural
settings, namely Malaysia. Structural equation modeling was
employed for data analysis and hypothesis testing. This study finding
has provided some insights that would likely affect students’
awareness towards using Facebook as an alternative learning
platform in the Malaysian higher learning institutions. At the end,
future direction is proposed.
Abstract: One of the key aspects of power quality improvement
in power system is the mitigation of voltage sags/swells and flicker.
Custom power devices have been known as the best tools for voltage
disturbances mitigation as well as reactive power compensation.
Dynamic Voltage Restorer (DVR) which is the most efficient and
effective modern custom power device can provide the most
commercial solution to solve several problems of power quality in
distribution networks. This paper deals with analysis and simulation
technique of DVR based on instantaneous power theory which is a
quick control to detect signals. The main purpose of this work is to
remove three important disturbances including voltage sags/swells
and flicker. Simulation of the proposed method was carried out on
two sample systems by using Matlab software environment and the
results of simulation show that the proposed method is able to
provide desirable power quality in the presence of wide range of
disturbances.
Abstract: Agro-industry is one of major industries that have
strong impacts on national economic incomes, growth, stability, and
sustainable development. Moreover, this industry also has strong
influences on social, cultural and political issues. Furthermore, this
industry, as producing primary and secondary products, is facing
challenges from such diverse factors such as demand inconsistency,
intense international competition, technological advancements and
new competitors. In order to maintain and to improve industry’s
competitiveness in both domestics and international markets, science
and technology are key factors. Besides hard sciences and
technologies, modern industrial engineering concepts such as Just in
Time (JIT) Total Quality Management (TQM), Quick Response
(QR), Supply Chain Management (SCM) and Lean can be very
effective to support to increase efficiency and effectiveness of these
agricultural products on world stage. Onion is one of Thailand’s
major export products which bring back national incomes. But, it is
also facing challenges in many ways. This paper focused its interests
in onion packing process and its related activities such as storage and
shipment from one of major packing plant and storage in Mae Wang
District, Chiang Mai, Thailand, by applying Toyota Production
System (TPS) or Lean concepts, to improve process capability
throughout the entire packing and distribution process which will be
profitable for the whole onion supply chain. And it will be beneficial
to other related agricultural products in Thailand and other ASEAN
countries.
Abstract: The structures obtained with the use of sandwich
technologies combine low weight with high energy absorbing
capacity and load carrying capacity. Hence, there is a growing and
markedly interest in the use of sandwiches with aluminum foam core
because of very good properties such as flexural rigidity and energy
absorption capability. In the current investigation, the static threepoint
bending tests were carried out on the sandwiches with
aluminum foam core and glass fiber reinforced polymer (GFRP)
skins at different values of support span distances aiming the analyses
of their flexural performance. The influence of the core thickness and
the GFRP skin type was reported in terms of peak load and energy
absorption capacity. For this purpose, the skins with two different
types of fabrics which have same thickness value and the aluminum
foam core with two different thicknesses were bonded with a
commercial polyurethane based flexible adhesive in order to combine
the composite sandwich panels. The main results of the bending tests
are: force-displacement curves, peak force values, absorbed energy,
collapse mechanisms and the effect of the support span length and
core thickness. The results of the experimental study showed that the
sandwich with the skins made of S-Glass Woven fabrics and with the
thicker foam core presented higher mechanical values such as load
carrying and energy absorption capacities. The increment of the
support span distance generated the decrease of the mechanical
values for each type of panels, as expected, because of the inverse
proportion between the force and span length. The most common
failure types of the sandwiches are debonding of the lower skin and
the core shear. The obtained results have particular importance for
applications that require lightweight structures with a high capacity
of energy dissipation, such as the transport industry (automotive,
aerospace, shipbuilding and marine industry), where the problems of
collision and crash have increased in the last years.
Abstract: A field study was conducted to evaluate the efficacy
of lavender for phytoremediation of contaminated soils. The
experiment was performed on an agricultural fields contaminated by
the Non-Ferrous-Metal Works near Plovdiv, Bulgaria. The
concentrations of Pb, Zn and Cd in lavender (roots, stems, leaves and
inflorescences) and in the essential oils of lavender were determined.
Lavender is a plant which is tolerant to heavy metals and can be
grown on contaminated soils, and which can be referred to the
hyperaccumulators of lead and the accumulators of cadmium and
zinc, and can be successfully used in the phytoremediation of heavy
metal contaminated soils. Favorable is also the fact that heavy metals
do not influence the development of the lavender, as well as on the
quality and quantity of the essential oil. The possibility of further
industrial processing will make lavender economically interesting
crops for farmers of phytoextraction technology.
Abstract: This work sets out to debate the tensions involved in
the processes of contamination and self-purification in the urban
space, particularly in the streams that run through the Buenos Aires
metropolitan area. For much of their course, those streams are piped;
their waters do not come into contact with the outdoors until they
have reached deeply impoverished urban areas with high levels of
environmental contamination. These are peripheral zones that, until
thirty years ago, were marshlands and fields. They are now densely
populated areas largely lacking in urban infrastructure.
The Cárcova neighborhood, where this project is underway, is in
the José León Suárez section of General San Martín county, Buenos
Aires province. A stretch of José León Suarez canal crosses the
neighborhood. Starting upstream, this canal carries pollutants due to
the sewage and industrial waste released into it. Further downstream,
in the neighborhood, domestic drainage is poured into the stream. In
this paper, we formulate a hypothesis diametrical to the one that
holds that these neighborhoods are the primary source of
contamination, suggesting instead that in the stretch of the canal that
runs through the neighborhood the stream’s waters are actually
cleaned and the sediments accumulate pollutants. Indeed, the
stretches of water that runs through these neighborhoods act as water
processing plants for the metropolis.
This project has studied the different organic-load polluting
contributions to the water in a certain stretch of the canal, the
reduction of that load over the course of the canal, and the
incorporation of pollutants into the sediments. We have found that
the surface water has considerable ability to self-purify, mostly due to
processes of sedimentation and adsorption. The polluting load is
accumulated in the sediments where that load stabilizes slowly by
means of anaerobic processes. In this study, we also investigated the
risks of sediment management and the use of the processes studied
here in controlled conditions as tools of environmental restoration.
Abstract: Recently, there is a lot of interest in the field of under
water optical wireless communication for short range because of
its high bandwidth. But in most of the previous works line of
sight propagation or single scattering of photons only considered.
In practical case this is not applicable because of beam blockage in
underwater and multiple scattering also occurred during the photons
propagation through water. In this paper we consider a non-line
of sight underwater wireless optical communication system with
multiple scattering and examine the performance of the system using
monte carlo simulation. The distribution scattering angle of photons
are modeled by Henyey-Greenstein method. The average bit error
rate is calculated using on-off keying modulation for different water
types.
Abstract: Behavioral aspects of experience such as will power
are rarely subjected to quantitative study owing to the numerous
complexities involved. Will is a phenomenon that has puzzled
humanity for a long time. It is a belief that will power of an individual
affects the success achieved by them in life. It is also thought that a
person endowed with great will power can overcome even the most
crippling setbacks in life while a person with a weak will cannot make
the most of life even the greatest assets. This study is an attempt
to subject the phenomena of will to the test of an artificial neural
network through a computational model. The claim being tested is
that will power of an individual largely determines success achieved
in life. It is proposed that data pertaining to success of individuals
be obtained from an experiment and the phenomenon of will be
incorporated into the model, through data generated recursively using
a relation between will and success characteristic to the model.
An artificial neural network trained using part of the data, could
subsequently be used to make predictions regarding data points in
the rest of the model. The procedure would be tried for different
models and the model where the networks predictions are found to
be in greatest agreement with the data would be selected; and used
for studying the relation between success and will.
Abstract: Indonesian higher education has experienced
significant changes over the last decade. In 1999, the government
published an overall strategy for decentralisation and enhancement of
local autonomy in many sectors, including (higher) education.
Indonesian higher education reforms have forced universities to
restructure their internal university governance to become more
entrepreneurial. These new types of internal university governance
are likely to affect the institutions’ leadership and management. This
paper discusses the approach and findings of a study on the
managerial leadership styles of deans in Indonesian universities. The
study aims to get a better understanding of styles exhibited by deans
manifested in their behaviours. Using the theories of reasoned action
and planned behaviour, in combination with the competing values
framework, a large-scale survey was conducted to gather information
on the deans’ behaviours, attitudes, subjective norms, and perceived
behavioural control. Based on the responses of a sample of 218
deans, the study identifies a number of leadership styles: the Master,
the Competitive Consultant, the Consensual Goal-Setter, the Focused
Team Captain, and the Informed Trust-Builder style. The study
demonstrates that attitudes are the primary determinant of the styles
that were found. Perceived behavioural control is a factor that
explains some managerial leadership styles. By understanding the
attitudes of deans in Indonesian universities, and their leadership
styles, universities can strengthen their management and governance,
and thus improve their effectiveness.
Abstract: Non contact evaluation of the thickness of paint
coatings can be attempted by different destructive and nondestructive
methods such as cross-section microscopy, gravimetric mass
measurement, magnetic gauges, Eddy current, ultrasound or
terahertz. Infrared thermography is a nondestructive and non-invasive
method that can be envisaged as a useful tool to measure the surface
thickness variations by analyzing the temperature response. In this
paper, the thermal quadrupole method for two layered samples heated
up with a pulsed excitation is firstly used. By analyzing the thermal
responses as a function of thermal properties and thicknesses of both
layers, optimal parameters for the excitation source can be identified.
Simulations show that a pulsed excitation with duration of ten
milliseconds allows obtaining a substrate-independent thermal
response. Based on this result, an experimental setup consisting of a
near-infrared laser diode and an Infrared camera was next used to
evaluate the variation of paint coating thickness between 60 μm and
130 μm on two samples. Results show that the parameters extracted
for thermal images are correlated with the estimated thicknesses by
the Eddy current methods. The laser pulsed thermography is thus an
interesting alternative nondestructive method that can be moreover
used for nonconductive substrates.
Abstract: We proposed a Hyperbolic Gompertz Growth Model
(HGGM), which was developed by introducing a shape parameter
(allometric). This was achieved by convoluting hyperbolic sine
function on the intrinsic rate of growth in the classical gompertz
growth equation. The resulting integral solution obtained
deterministically was reprogrammed into a statistical model and used
in modeling the height and diameter of Pines (Pinus caribaea). Its
ability in model prediction was compared with the classical gompertz
growth model, an approach which mimicked the natural variability of
height/diameter increment with respect to age and therefore provides
a more realistic height/diameter predictions using goodness of fit
tests and model selection criteria. The Kolmogorov Smirnov test and
Shapiro-Wilk test was also used to test the compliance of the error
term to normality assumptions while the independence of the error
term was confirmed using the runs test. The mean function of top
height/Dbh over age using the two models under study predicted
closely the observed values of top height/Dbh in the hyperbolic
gompertz growth models better than the source model (classical
gompertz growth model) while the results of R2, Adj. R2, MSE and
AIC confirmed the predictive power of the Hyperbolic Gompertz
growth models over its source model.
Abstract: The emerging markets of post-USSR countries have
attracted Western multinational companies; however, weak
institutions and unstable host country environments have hindered the
implementation of successful management practices. The Ukrainian
market, in light of recent events, is particularly interesting to study
for its compatibility with Western businesses. This paper focuses on
factors that can facilitate or inhibit the transfer of human resource
management practices from Western headquarters to Ukrainian
subsidiaries. To explain the national context’s effects better, a
business systems approach has been applied to a qualitative study of
16 wholly owned Western subsidiaries, dissecting the reasons for a
weak integration of Western practices in Ukraine. Results show that
underdeveloped institutions have forced companies to develop
additional practices that compensate for national weaknesses, as well
as to adjust to a constantly changing environment. Flexibility and
local responsiveness were observed as vital for success in Ukraine.
Abstract: The purpose of the paper is to examine the most
critical and important factor which will affect the implementation of
Total Quality Management (TQM) in the construction industry in the
United Arab Emirates. It also examines the most effected Project
outcome from implementing TQM. A framework was also proposed
depending on the literature studies. The method used in this paper is a
quantitative study. A survey with a sample of 60 respondents was
created and distributed in a construction company in Abu Dhabi,
which includes 15 questions to examine the most critical factor that
will affect the implementation of TQM in addition to the most
effected project outcome from implementing TQM. The survey
showed that management commitment is the most important factor in
implementing TQM in a construction company. Also it showed that
Project cost is most effected outcome from the implementation of
TQM.
Management commitment is very important for implementing
TQM in any company. If the management loose interest in quality
then everyone in the organization will do so. The success of TQM
will depend mostly on the top of the pyramid. Also cost is reduced
and money is saved when the project team implement TQM. While if
no quality measures are present within the team, the project will
suffer a commercial failure.
Based on literature, more factors can be examined and added to
the model. In addition, more construction companies could be
surveyed in order to obtain more accurate results. Also this study
could be conducted outside the United Arab Emirates for further
enchantment.
Abstract: An Australian manufacturer has fabricated an
innovative GFRP sandwich panel made from E-glass fiber skin and a
modified phenolic core for structural applications. Debonding, which
refers to separation of skin from the core material in composite
sandwiches, is one of the most common types of damage in
composites. The presence of debonding is of great concern because it
not only severely affects the stiffness but also modifies the dynamic
behaviour of the structure. Generally it is seen that the majority of
research carried out has been concerned about the delamination of
laminated structures whereas skin-core debonding has received
relatively minor attention. Furthermore it is observed that research
done on composite slabs having multiple skin-core debonding is very
limited. To address this gap, a comprehensive research investigating
dynamic behaviour of composite panels with single and multiple
debonding is presented. The study uses finite-element modelling and
analyses for investigating the influence of debonding on free
vibration behaviour of single and multilayer composite sandwich
panels. A broad parametric investigation has been carried out by
varying debonding locations, debonding sizes and support conditions
of the panels in view of both single and multiple debonding.
Numerical models were developed with Strand7 finite element
package by innovatively selecting the suitable elements to diligently
represent their actual behavior. Three-dimensional finite element
models were employed to simulate the physically real situation as
close as possible, with the use of an experimentally and numerically
validated finite element model. Comparative results and conclusions
based on the analyses are presented. For similar extents and locations
of debonding, the effect of debonding on natural frequencies appears
greatly dependent on the end conditions of the panel, giving greater
decrease in natural frequency when the panels are more restrained.
Some modes are more sensitive to debonding and this sensitivity
seems to be related to their vibration mode shapes. The fundamental
mode seems generally the least sensitive mode to debonding with
respect to the variation in free vibration characteristics. The results
indicate the effectiveness of the developed three dimensional finite
element models in assessing debonding damage in composite
sandwich panels.