Abstract: Since the advent of modern architecture, notions of free plan and transparency have proliferated well into current trends. The movement’s notion of a spatially homogeneous, open and limitless ‘free plan’ contrasts with the spatially heterogeneous ‘series of rooms’ defined by load bearing walls, which in turn triggered new notions of transparency created by vast expanses of glazed walls. Similarly, transparency was also dichotomized as something that was physical or optical, as well as something conceptual, akin to spatial organization. As opposed to merely accepting the duality and possible incompatibility of these dichotomies, this paper seeks to ask how can space be both literally and phenomenally transparent, as well as exhibit both homogeneous and heterogeneous qualities? This paper explores this potential destabilization or blurring of spatial phenomena by dissecting the transparent layers and volumes of a series of selected case studies to investigate how different architects have devised strategies of spatial ambiguity and interpenetration. Projects by Peter Eisenman, Sou Fujimoto, and SANAA will be discussed and analyzed to show how the superimposition of geometries and spaces achieve different conditions of layering, transparency, and interstitiality. Their particular buildings will be explored to reveal various innovative kinds of spatial interpenetration produced through the articulate relations of the elements of architecture, which challenge conventional perceptions of interior and exterior whereby visual homogeneity blurs with spatial heterogeneity. The results show how spatial conceptions such as interpenetration and transparency have the ability to subvert not only inside-outside dialectics, but could also produce multiple degrees of interiority within complex and indeterminate spatial dimensions in constant flux as well as present alternative forms of social interaction.
Abstract: The microstructure and texture evolution of cryo rolled and annealed ductile TaHfNbZrTi refractory high entropy alloy was investigated. To obtain that, the alloy is severely cryo rolled and subsequently annealed for the recrystallization process. The cryo rolled – 90% shows the presence of very fine grains and microstructural heterogeneity. The cryo rolled samples are annealed at a temperature ranging from 800°C to 1400°C, the partial recrystallization is observed at 800°C annealed condition, and at higher annealing temperatures the complete recrystallization process is noticed. The development of ND fiber texture is observed after the annealing.
Abstract: The refractory alloys are crucial for high-temperature applications to improve performance and reduce cost. They are used in several applications such as aerospace, outer space, military and defense, nuclear powerplants, automobiles, and industry. The conventional refractory alloys show greater stability at high temperatures and in contrast they have operational limitations due to their low melting temperatures. However, there is a huge requirement to improve the refractory alloys’ operational temperatures and replace the conventional alloys. The newly emerging refractory high entropy alloys (RHEAs) could be alternative materials for conventional refractory alloys and fulfill the demands and requirements of various practical applications in the future. The RHEA TaHfNbZrTi was prepared through an arc melting process. The annealing behavior of severely deformed equiatomic RHEATaHfNbZrTi has been investigated. To obtain deformed condition, the alloy is cold-rolled to 90% thickness reduction and then subjected to an annealing process to observe recrystallization and microstructural evolution in the range of 800 °C to 1400 °C temperatures. The cold-rolled – 90% condition shows the presence of microstructural heterogeneity. The annealing microstructure of 800 °C temperature reveals that partial recrystallization and further annealing treatment carried out annealing treatment in the range of 850 °C to 1400 °C temperatures exhibits completely recrystallized microstructures, followed by coarsening with a degree of annealing temperature. The deformed and annealed conditions featured the development of body-centered cubic (BCC) fiber textures. The experimental investigation of heavy deformation and followed by high-temperature annealing up to 1400 °C temperature will contribute to the understanding of microstructure and texture evolution of emerging RHEAs.
Abstract: High grade ovarian epithelial cancer (OEC) is the most fatal gynecological cancer and poor prognosis of this entity is closely related to considerable intratumoral genetic heterogeneity. By examining imaging data, it is possible to assess the heterogeneity of tumorous tissue. This study presents a methodology for aligning, segmenting and finally visualizing information from various magnetic resonance imaging series, in order to construct 3D models of heterogeneity maps from the same tumor in OEC patients. The proposed system may be used as an adjunct digital tool by health professionals for personalized medicine, as it allows for an easy visual assessment of the heterogeneity of the examined tumor.
Abstract: Pseudomonas aeruginosa is an opportunistic pathogen that forms surface-associated microbial communities (biofilms) on artificial implant devices and on human tissue. Biofilm infections are difficult to treat with antibiotics, in part, because the bacteria in biofilms are physiologically heterogeneous. One measure of biological heterogeneity in a population of cells is to quantify the cellular concentrations of ribosomes, which can be probed with fluorescently labeled nucleic acids. The fluorescent signal intensity following fluorescence in situ hybridization (FISH) analysis correlates to the cellular level of ribosomes. The goals here are to provide computationally and statistically robust approaches to automatically quantify cellular heterogeneity in biofilms from a large library of epifluorescent microscopy FISH images. In this work, the initial steps were developed toward these goals by developing an automated biofilm detection approach for use with FISH images. The approach allows rapid identification of biofilm regions from FISH images that are counterstained with fluorescent dyes. This methodology provides advances over other computational methods, allowing subtraction of spurious signals and non-biological fluorescent substrata. This method will be a robust and user-friendly approach which will enable users to semi-automatically detect biofilm boundaries and extract intensity values from fluorescent images for quantitative analysis of biofilm heterogeneity.
Abstract: One of the major sources of learners' professional difficulties is their heterogeneity. Whether on cognitive, social, cultural or emotional level, learners being part of the same group have many differences. These differences do not allow to apply the same learning process at all learners. Thus, an optimal learning path for one, is not necessarily the same for the other. We present in this paper a model-oriented service to offer to each learner a personalized learning path to acquire the targeted skills.
Abstract: Non contact evaluation of the thickness of paint
coatings can be attempted by different destructive and nondestructive
methods such as cross-section microscopy, gravimetric mass
measurement, magnetic gauges, Eddy current, ultrasound or
terahertz. Infrared thermography is a nondestructive and non-invasive
method that can be envisaged as a useful tool to measure the surface
thickness variations by analyzing the temperature response. In this
paper, the thermal quadrupole method for two layered samples heated
up with a pulsed excitation is firstly used. By analyzing the thermal
responses as a function of thermal properties and thicknesses of both
layers, optimal parameters for the excitation source can be identified.
Simulations show that a pulsed excitation with duration of ten
milliseconds allows obtaining a substrate-independent thermal
response. Based on this result, an experimental setup consisting of a
near-infrared laser diode and an Infrared camera was next used to
evaluate the variation of paint coating thickness between 60 μm and
130 μm on two samples. Results show that the parameters extracted
for thermal images are correlated with the estimated thicknesses by
the Eddy current methods. The laser pulsed thermography is thus an
interesting alternative nondestructive method that can be moreover
used for nonconductive substrates.
Abstract: Many researchers have suggested the use of zero inflated Poisson (ZIP) and zero inflated negative binomial (ZINB) models in modeling overdispersed medical count data with extra variations caused by extra zeros and unobserved heterogeneity. The studies indicate that ZIP and ZINB always provide better fit than using the normal Poisson and negative binomial models in modeling overdispersed medical count data. In this study, we proposed the use of Zero Inflated Inverse Trinomial (ZIIT), Zero Inflated Poisson Inverse Gaussian (ZIPIG) and zero inflated strict arcsine models in modeling overdispered medical count data. These proposed models are not widely used by many researchers especially in the medical field. The results show that these three suggested models can serve as alternative models in modeling overdispersed medical count data. This is supported by the application of these suggested models to a real life medical data set. Inverse trinomial, Poisson inverse Gaussian and strict arcsine are discrete distributions with cubic variance function of mean. Therefore, ZIIT, ZIPIG and ZISA are able to accommodate data with excess zeros and very heavy tailed. They are recommended to be used in modeling overdispersed medical count data when ZIP and ZINB are inadequate.
Abstract: The paper aims at investigating influence of medium
capacity on linear adsorbed solute dispersion into chemically
heterogeneous fixed beds. A discrete chemical heterogeneity
distribution is considered in the one-dimensional advectivedispersive
equation. The partial differential equation is solved using
finite volumes method based on the Adam-Bashforth algorithm.
Increased dispersion is estimated by comparing breakthrough curves
second order moments and keeping identical hydrodynamic
properties. As a result, dispersion increase due to chemical
heterogeneity depends on the column size and surprisingly on the
solid capacity. The more intense capacity is, the more important
solute dispersion is. Medium length which is known to favour this
effect vanishing according to the linear adsorption in fixed bed seems
to create nonmonotonous variation of dispersion because of the
heterogeneity. This nonmonotonous behaviour is also favoured by
high capacities.
Abstract: Given a parallel program to be executed on a heterogeneous
computing system, the overall execution time of the program
is determined by a schedule. In this paper, we analyze the worst-case
performance of the list scheduling algorithm for scheduling tasks
of a parallel program in a mixed-machine heterogeneous computing
system such that the total execution time of the program is minimized.
We prove tight lower and upper bounds for the worst-case
performance ratio of the list scheduling algorithm. We also examine
the average-case performance of the list scheduling algorithm. Our
experimental data reveal that the average-case performance of the list
scheduling algorithm is much better than the worst-case performance
and is very close to optimal, except for large systems with large
heterogeneity. Thus, the list scheduling algorithm is very useful in
real applications.
Abstract: To determine if the murine insulinoma, β-TC-6, is a
suitable substitute for primary pancreatic β-cells in the study of β-
cell functional heterogeneity, we used three distinct functional assays
to ascertain the cell line-s response to glucose or a glucose analog.
These assays include: (i) a 2-NBDG uptake assay; (ii) a calcium
influx assay, and; (iii) a quinacrine secretion assay. We show that a
population of β-TC-6 cells endocytoses the glucose analog, 2-
NBDG, at different rates, has non-uniform intracellular calcium ion
concentrations and releases quinacrine at different rates when
challenged with glucose. We also measured the Km for β-TC-6
glucose uptake to be 46.9 mM and the Vm to be 8.36 x 10-5
mmole/million cells/min. These data suggest that β-TC-6 might be
used as an alternative to primary pancreatic β-cells for the study of
glucose-dependent β-cell functional heterogeneity.
Abstract: This paper deals with dynamic load balancing using PVM. In distributed environment Load Balancing and Heterogeneity are very critical issues and needed to drill down in order to achieve the optimal results and efficiency. Various techniques are being used in order to distribute the load dynamically among different nodes and to deal with heterogeneity. These techniques are using different approaches where Process Migration is basic concept with different optimal flavors. But Process Migration is not an easy job, it impose lot of burden and processing effort in order to track each process in nodes. We will propose a dynamic load balancing technique in which application will intelligently balance the load among different nodes, resulting in efficient use of system and have no overheads of process migration. It would also provide a simple solution to problem of load balancing in heterogeneous environment.
Abstract: In this paper we present a new approach to deal with
image segmentation. The fact that a single segmentation result do not
generally allow a higher level process to take into account all the
elements included in the image has motivated the consideration of
image segmentation as a multiobjective optimization problem. The
proposed algorithm adopts a split/merge strategy that uses the result
of the k-means algorithm as input for a quantum evolutionary
algorithm to establish a set of non-dominated solutions. The
evaluation is made simultaneously according to two distinct features:
intra-region homogeneity and inter-region heterogeneity. The
experimentation of the new approach on natural images has proved
its efficiency and usefulness.
Abstract: The zero inflated models are usually used in modeling
count data with excess zeros where the existence of the excess zeros
could be structural zeros or zeros which occur by chance. These type
of data are commonly found in various disciplines such as finance,
insurance, biomedical, econometrical, ecology, and health sciences
which involve sex and health dental epidemiology. The most popular
zero inflated models used by many researchers are zero inflated
Poisson and zero inflated negative binomial models. In addition, zero
inflated generalized Poisson and zero inflated double Poisson models
are also discussed and found in some literature. Recently zero
inflated inverse trinomial model and zero inflated strict arcsine
models are advocated and proven to serve as alternative models in
modeling overdispersed count data caused by excessive zeros and
unobserved heterogeneity. The purpose of this paper is to review
some related literature and provide a variety of examples from
different disciplines in the application of zero inflated models.
Different model selection methods used in model comparison are
discussed.
Abstract: Mobile devices, which are progressively surrounded
in our everyday life, have created a new paradigm where they
interconnect, interact and collaborate with each other. This network
can be used for flexible and secure coordinated sharing. On the other
hand Grid computing provides dependable, consistent, pervasive, and
inexpensive access to high-end computational capabilities. In this
paper, efforts are made to map the concepts of Grid on Ad-Hoc
networks because both exhibit similar kind of characteristics like
Scalability, Dynamism and Heterogeneity. In this context we
propose “Mobile Ad-Hoc Services Grid – MASGRID".