Abstract: In recent years application of natural antimicrobials
instead of conventional ones, due to their hazardous effects on health,
has got serious attentions. On the basis of the results of different
studies, chitosan, a natural bio-degradable and non-toxic
biopolysaccharide derived from chitin, has potential to be used as a
natural antimicrobial. Chitosan has exhibited high antimicrobial
activity against a wide variety of pathogenic and spoilage
microorganisms, including fungi, and Gram-positive and Gramnegative
bacteria. The antimicrobial action is influenced by intrinsic
factors such as the type of chitosan, the degree of chitosan
polymerization and extrinsic factors such as the microbial organism,
the environmental conditions and presence of the other components.
The use of chitosan in food systems should be based on sufficient
knowledge of the complex mechanisms of its antimicrobial mode of
action. In this article we review a number of studies on the
investigation of chitosan antimicrobial properties and application of
them in culture and food mediums.
Abstract: Children and adolescents developing in the worlds of today are facing a getting array of new and old challenges. School counselling is improving rapidly in contemporary education systems around the world. It can be said that counselling system in Turkey was newly borning. In this study, “Family of the Blood" activity is improved with respect to compherensive guidance school program. The sample included 22 adolescents who were high school students. The activity was carried out in 4 sessions, each of which lasted 45 minutes. In the first session, students- personal-social needs were determined. In the second session, in order to warm up, the students were asked three questions consisting of the constructional aspect. In the third session, the counselor and the teacher shared the results of students- responses obtained in the previous session. In the fourth session, the tables formed by students were presented in the classroom. In order to evaluate the activity, three questions were asked of the teacher and counselor. According to the results, the lesson aims of curriculum and counselling aims of curriculum were attained. In the light of literature, the results were discussed and some suggestions were made. It is taken into consideration that the activitiy was beneficial in many respects, similar studies should be carried out in the near future.
Abstract: The connection between solar activity and adverse phenomena in the Earth’s environment that can affect space and ground based technologies has spurred interest in Space Weather (SW) research. A great effort has been put on the development of suitable models that can provide advanced forecast of SW events. With the progress in computational technology, it is becoming possible to develop operational large scale physics based models which can incorporate the most important physical processes and domains of the Sun-Earth system. In order to enhance our SW prediction capabilities we are developing advanced numerical tools. With operational requirements in mind, our goal is to develop a modular simulation framework of propagation of the disturbances from the Sun through interplanetary space to the Earth. Here, we report and discuss on the development of coronal field and solar wind components for a large scale MHD code. The model for these components is based on a potential field source surface model and an empirical Wang-Sheeley-Arge solar wind relation.
Abstract: An application framework provides a reusable design
and implementation for a family of software systems. Frameworks
are introduced to reduce the cost of a product line (i.e., a family of
products that shares the common features). Software testing is a timeconsuming
and costly ongoing activity during the application
software development process. Generating reusable test cases for the
framework applications during the framework development stage,
and providing and using the test cases to test part of the framework
application whenever the framework is used reduces the application
development time and cost considerably. This paper introduces the
Framework Interface State Transition Tester (FIST2), a tool for
automated unit testing of Java framework applications. During the
framework development stage, given the formal descriptions of the
framework hooks, the specifications of the methods of the
framework-s extensible classes, and the illegal behavior description
of the Framework Interface Classes (FICs), FIST2 generates unitlevel
test cases for the classes. At the framework application
development stage, given the customized method specifications of
the implemented FICs, FIST2 automates the use, execution, and
evaluation of the already generated test cases to test the implemented
FICs. The paper illustrates the use of the FIST2 tool for testing
several applications that use the SalesPoint framework.
Abstract: Silver nanoparticles were prepared by chemical reduction method. Silver nitrate was taken as the metal precursor and hydrazine hydrate as a reducing agent. The formation of the silver nanoparticles was monitored using UV-Vis absorption spectroscopy. The UV-Vis spectroscopy revealed the formation of silver nanopart├¡cles by exhibing the typical surface plasmon absorption maxima at 418-420 nm from the UV–Vis spectrum. Comparison of theoretical (Mie light scattering theory) and experimental results showed that diameter of silver nanoparticles in colloidal solution is about 60 nm. We have used energy-dispersive spectroscopy (EDX), X-ray diffraction (XRD), transmission electron microscopy (TEM) and, UV–Vis spectroscopy to characterize the nanoparticles obtained. The energy-dispersive spectroscopy (EDX) of the nanoparticles dispersion confirmed the presence of elemental silver signal no peaks of other impurity were detected. The average size and morphology of silver nanoparticles were determined by transmission electron microscopy (TEM). TEM photographs indicate that the nanopowders consist of well dispersed agglomerates of grains with a narrow size distribution (40 and 60 nm), whereas the radius of the individual particles are between 10 and 20 nm. The synthesized nanoparticles have been structurally characterized by X-ray diffraction and transmission high-energy electron diffraction (HEED). The peaks in the XRD pattern are in good agreement with the standard values of the face-centered-cubic form of metallic silver (ICCD-JCPDS card no. 4-0787) and no peaks of other impurity crystalline phases were detected. Additionally, the antibacterial activity of the nanopart├¡culas dispersion was measured by Kirby-Bauer method. The nanoparticles of silver showed high antimicrobial and bactericidal activity against gram positive bacteria such as Escherichia Coli, Pseudimonas aureginosa and staphylococcus aureus which is a highly methicillin resistant strain.
Abstract: The objective of the present study was to examine the
dose-response relationships between antioxidant parameters and liver
contaminant levels of Kazakhstan light crude oil (KLCO) in albino
rats. The animals were repeatedly exposed, by intraperitoneal
injection, to low dosages (0.5–1.5 ml/kg) of KLCO. Rats exposed to
these doses levels did not show any apparent symptoms of
intoxication. Serum aminotransferases increased significantly
(p
Abstract: We present a Large-Eddy simulation of a vortex cell
with circular shaped. The results show that the flow field can be sub
divided into four important zones, the shear layer above the cavity,
the stagnation zone, the vortex core in the cavity and the boundary
layer along the wall of the cavity. It is shown that the vortex core
consits of solid body rotation without much turbulence activity. The
vortex is mainly driven by high energy packets that are driven into the
cavity from the stagnation point region and by entrainment of fluid
from the cavity into the shear layer. The physics in the boundary
layer along the cavity-s wall seems to be far from that of a canonical
boundary layer which might be a crucial point for modelling this
flow.
Abstract: The peel of dragon fruit is a byproduct left over after consuming. Normally, the use of plants as antioxidant source must be dried before further process. Therefore, the aim of this study is interesting to dry the peel by heat pump dryer (45 ºC) and fluidized bed dryer (110 º C) compared with the sun drying method. The sample with initial moisture content of about 85-91% wet basis was dried down to about 10% wet basis where it took 620 and 25 min for heat pump dryer and fluidized bed dryer, respectively. However, the sun drying took about 900 min to dry the peel. After that, sample was evaluated antioxidant activity, -carotene and betalains contents. The results found that the antioxidant activity and betalains contents of dried peel obtained from heat pump and fluidized bed dryings were significantly higher than that sun drying (p 0.05). Moreover, the drying by heat pump provided the highest -carotene content.
Abstract: EcoDam is an adenine-N6 DNA methyltransferase
that methylates the GATC sites in the Escherichia coli genome.
DNA-adenine methylation is not present in higher eukaryotes
including humans. These observations raise the possibility that dam
inhibitors may be used as anti-microbial agents. Polyphosphate
(Poly(P)) is an important metabolite and signaling molecule in
prokaryotes and eukaryotes. Here, by using gel retardation
experiments to investigate the competition of DNA binding by
EcoDam in the presence of polyphosphate, we found that Poly (P)
strongly interferes with DNA binding by EcoDam, while same
concentration of monophosphate does not. In addition, we
demonstrated that Poly (P) binding inhibits the activity of EcoDam
and our results suggest that Poly (P) led to strong inhibition of the
EcoDam catalytic activity, while monophosphate had only moderate
effect.
Abstract: Our results showed that treatment with both
cyclooxygenase (COX1 or COX2) inhibitors impair reproduction
parameters of the medaka. Resveratrol (COX1 inhibitor) caused an
decrease in the number of spawning females at the first week of
feeding fish with experimental diets. In the group treated with NS-
398 (COX2 inhibitor) we found the lowest sperm velocity parameters
and decreased linearity of movement. The ovaries of the medaka fed
feed supplemented with Resveratrol or NS-398 were confirmed to
have a lower share of matured oocytes however during the
experiment (four weeks) the number of eggs spawned by females was
similar. Both inhibitors in fish diet (20 mg/kg body weight/day)
caused a decrease in the embryo survival. Our results revealed that
for the medaka female reproduction, activity of both COX enzymes
might be necessary whereas males reproduction competence, as
expressed by sperm motility parameters, might be related to COX2
activity.
Abstract: Antibacterial activity of Plumeria alba (Frangipani)
petals methanolic extracts were evaluated against Escherichia coli,
Proteus vulgaris,Staphylococcus aureus, Klebsiella pneumoniae,
Pseudomonas aeruginosa, Staphylococcus saprophyticus,
Enterococcus faecalis and Serratia marcescens by using disk
diffusion method. Concentration extracts (80 %) showed the highest
inhibition zone towards Escherichia coli (14.3 mm). Frangipani
extract also showed high antibacterial activity against
Staphylococcus saprophyticus, Proteus vulgaris and Serratia
marcescens, but not more than the zones of the positive control used.
Comparison between two broad specrum antibiotics to frangipani
extracts showed that the 80 % concentration extracts produce the
same zone of inhibition as Streptomycin. Frangipani extracts showed
no bacterial activity towards Klebsiella pneumoniae, Pseudomonas
aeruginosa and Enterococcus faecalis. There are differences in the
sensitivity of different bacteria to frangipani extracts, suggesting that
frangipani-s potency varies between these bacteria. The present
results indicate that frangipani showed significant antibacterial
activity especially to Escherichia coli.
Abstract: Extracellular ubiquitin in vivo effect on regenerative liver cells and liver histoarchitectonics has been studied. Experiments were performed on mature female white rats. Partial hepatectomy was made using the modified method of Higgins and Anderson. Standard histopathological assessment of liver tissue was used. Proliferative activity of hepatocytes was analyzed by colchicine mitotic index and immunohistochemical staining on ki67. We have found that regardless of number of injections and dose of extracellular ubiquitin liver histology has not been changed, so at tissue level no effect was observed. In vivo double injection of ubiquitin significantly decreases the mitotic activity at 32 hour point after partial hepatectomy. Thus, we can conclude that in vivo injected extracellular ubiquitin inhibits proliferative activity of hepatocytes in partially hepatectomyzed rats.
Abstract: In the paper a detailed analysis of the dynamic
response of a cooling tower shell to mining tremors originated from
two main regions of mining activity in Poland (Upper Silesian Coal
Basin and Legnica-Glogow Copper District) was presented. The
representative time histories registered in the both regions were used
as ground motion data in calculations of the dynamic response of the
structure. It was proved that the dynamic response of the shell is
strongly dependent not only on the level of vibration amplitudes but
on the dominant frequency range of the mining shock typical for the
mining region as well. Also a vertical component of vibrations
occurred to have considerable influence on the total dynamic
response of the shell. Finally, it turned out that non-uniformity of
kinematic excitation resulting from spatial variety of ground motion
plays a significant role in dynamic analysis of large-dimensional
shells under mining shocks.
Abstract: Exposure to radon occurs when breathing airborne
radon while using water: showering, washing dishes, cooking, and
drinking water that contain radon. The results of radon activity
measurements in water from public drinking fountain in city of Novi
Sad, Serbia is presented in this paper. Radon level in some samples
exceeded EPA (Environmental Protection Agency) recommendation
for maximum contaminant level (MCL) for radon in drinking water
of 11.1 Bq/l.
Abstract: The k-nearest neighbors (knn) is a simple but effective method of classification. In this paper we present an extended version of this technique for chemical compounds used in High Throughput Screening, where the distances of the nearest neighbors can be taken into account. Our algorithm uses kernel weight functions as guidance for the process of defining activity in screening data. Proposed kernel weight function aims to combine properties of graphical structure and molecule descriptors of screening compounds. We apply the modified knn method on several experimental data from biological screens. The experimental results confirm the effectiveness of the proposed method.
Abstract: The term interactive education indicates the meaning
related with multidisciplinary aspects of distance education following
contemporary means around a common basis with different
functional requirements. The aim of this paper is to reflect the new
techniques in education with the new methods and inventions. These
methods are better supplied by interactivity. The integration of
interactive facilities in the discipline of education with distance
learning is not a new concept but in addition the usage of these
methods on design issue is newly being adapted to design education.
In this paper the general approach of this method and after the
analysis of different samples, the advantages and disadvantages of
these approaches are being identified. The method of this paper is to
evaluate the related samples and then analyzing the main hypothesis.
The main focus is to mention the formation processes of this
education. Technological developments in education should be
filtered around the necessities of the design education and the
structure of the system could then be formed or renewed. The
conclusion indicates that interactive methods of education in design
issue is a meaning capturing not only technical and computational
intelligence aspects but also aesthetical and artistic approaches
coming together around the same purpose.
Abstract: Public sector corruption has long-term and damaging
effects that are deep and broad. Addressing corruption relies on
understanding the drivers that precipitate acts of corruption and
developing educational programs that target areas of vulnerability.
This paper provides an innovative approach to explore the nature of
corruption by drawing on the perceptions and ideas of a group of
public servants who have been part of a corruption investigation. The
paper examines these reflections through the ideas of Pierre Bourdieu
and Alfred Schutz to point to some of the steps that can lead to
corrupt activity. The paper demonstrates that phenomenological
inquiry is useful in the exploration of corruption and, as a theoretical
framework, it highlights that corruption emerges through a
combination of conflict, doubt and uncertainty. The paper calls for
anti-corruption education programs to be attentive to way in which
these conditions can influence the steps into corruption.
Abstract: Using the concept of measure of noncompactness, we present some results concerning the existence, uniform local attractivity and global attractivity of solutions for a functional integral equation. Our results improve and extend some previous known results and based on weaker conditions. Some examples which show that our results are applicable when the previous results are inapplicable are also included.
Abstract: In this work we evaluate the possibility of predicting
the emotional state of a person based on the EEG. We investigate
the problem of classifying valence from EEG signals during
the presentation of affective pictures, utilizing the "frontal EEG
asymmetry" phenomenon. To distinguish positive and negative
emotions, we applied the Common Spatial Patterns algorithm.
In contrast to our expectations, the affective pictures did not
reliably elicit changes in frontal asymmetry. The classifying task
thereby becomes very hard as reflected by the poor classifier
performance. We suspect that the masking of the source of the
brain activity related to emotions, coming mostly from deeper
structures in the brain, and the insufficient emotional engagement
are among main reasons why it is difficult to predict the emotional
state of a person.
Abstract: Chemical reaction and diffusion are important phenomena in quantitative neurobiology and biophysics. The knowledge of the dynamics of calcium Ca2+ is very important in cellular physiology because Ca2+ binds to many proteins and regulates their activity and interactions Calcium waves propagate inside cells due to a regenerative mechanism known as calcium-induced calcium release. Buffer-mediated calcium diffusion in the cytosol plays a crucial role in the process. A mathematical model has been developed for calcium waves by assuming the buffers are in equilibrium with calcium i.e., the rapid buffering approximation for a one dimensional unsteady state case. This model incorporates important physical and physiological parameters like dissociation rate, diffusion rate, total buffer concentration and influx. The finite difference method has been employed to predict [Ca2+] and buffer concentration time course regardless of the calcium influx. The comparative studies of the effect of the rapid buffered diffusion and kinetic parameters of the model on the concentration time course have been performed.