Abstract: In molecular biology, microarray technology is widely and successfully utilized to efficiently measure gene activity. If working with less studied organisms, methods to design custom-made microarray probes are available. One design criterion is to select probes with minimal melting temperature variances thus ensuring similar hybridization properties. If the microarray application focuses on the investigation of metabolic pathways, it is not necessary to cover the whole genome. It is more efficient to cover each metabolic pathway with a limited number of genes. Firstly, an approach is presented which minimizes the overall melting temperature variance of selected probes for all genes of interest. Secondly, the approach is extended to include the additional constraints of covering all pathways with a limited number of genes while minimizing the overall variance. The new optimization problem is solved by a bottom-up programming approach which reduces the complexity to make it computationally feasible. The new method is exemplary applied for the selection of microarray probes in order to cover all fungal secondary metabolite gene clusters for Aspergillus terreus.
Abstract: Hydrodesulfurization (HDS) of dibenzothiophene
(DBT) in a high pressure batch reactor was done at 320 °C on
CoMoS/Al2O3-B2O3 (4, 10, and 16 wt. % of Boria) using nhexadecane
as solvent, dimethyldisulfide (DMDS) in tetradecane as
sulfur agent, and stirring at 1000 rpm. The effects of boria were
investigated by using X-ray diffraction (XRD), Temperature
programmed desorption (TPD) of ammonia, and Brunauer-Emmet-
Teller (BET) experiments. The results showed that the catalyst
prepared with low boria content (4 wt. %) had HDS activity (in
pseudo first order kinetic constant basis) value ~1.45 times higher to
that of CoMoS/Al2O3 catalyst.
Abstract: The biological activity of A. pullulans isolates against
species of the genus Fusarium, bacteria of the genus Azotobacter and
pseudomonads colonizing wheat kernels was evaluated. A field
experiment was carried out in 2009-2011, in north-eastern Poland.
Winter wheat (cv. Bogatka) plants were sprayed with a cell
suspension of A. pullulans at a density of 106 - 108 per cm3 water at
the stem elongation stage and the heading stage. Untreated plants
served as control. The abundance of epiphytic yeasts, bacteria of the
genus Azotobacter, pseudomonads and Fusarium pathogens on wheat
grain was estimated at harvest and after six months’ storage. The
average size of yeast communities was significantly greater on wheat
kernels treated with a cell suspension of A. pullulans, compared with
control samples. In 2010-2011, biological control reduced the
abundance of some species of the genus Fusarium.
Abstract: The Kowsar dam supply water for different usages
such as drinking, industrial, agricultural and aquaculture farms
usages and located next to the city of Dehdashat in Kohgiluye and
Boyerahmad province in southern Iran. There are some towns and
villages on the Kowsar dam watersheds, which Dehdasht and Choram
are the most important and populated cities in this area. The study
was undertaken to assess the status of water quality in the urban areas
of the Kowsar dam. A total of 28 water samples were collected from
6 stations on surface water and 1 station from groundwater on the
watershed of the Kowsar dam. All the samples were analyzed for Ni
concentration using standard procedures. The results were compared
with other national and international standards. Among the analyzed
samples, as the maximum value of Nickel (0.01 mg/L) was observed
on the station 2 at the autumn 2010, all the samples analyzed were
within the maximum admissible limits by the United States
Environmental Protection Agency, EU, WHO and the Iranian. In
general results of the present study have shown that a Ni mean value
of station No. 2 with 0.006 mg/L is higher than the other stations. Ni
level of all samples and stations have had normal values and this is an
indication of pollution potential and hazards because of human
activity and waste water of towns in the areas, which can effect on
human health implications in future. This research, therefore,
recommends the government and other responsible authorities to take
suitable improving measures in the Kowsar dam watersheds.
Abstract: Bicycle usage for exercise, recreation, and commuting
to work in Australia shows that pedal cycling is the fourth most
popular activity with 10.6% increase in participants between 2001
and 2007. As with other means of transport, accident and injury
becomes common although mandatory bicycle helmet wearing has
been introduced. The research aims to develop a face surrogate made
of sandwich of rigid foam and rubber sheets to represent human
facial bone under blunt impact. The facial surrogate will serve as an
important test device for further development of facial-impact
protection for cyclist. A test procedure was developed to simulate the
energy of impact and record data to evaluate the effect of impact on
facial bones. Drop tests were performed to establish a suitable
combination of materials. It was found that the sandwich structure of
rigid extruded-polystyrene foam (density of 40 kg/m3 with a pattern
of 6-mm-holes), Neoprene rubber sponge, and Abrasaflex rubber
backing, had impact characteristics comparable to that of human
facial bone. In particular, the foam thickness of 30 mm and 25 mm
was found suitable to represent human zygoma (cheekbone) and
maxilla (upper-jaw bone), respectively.
Abstract: Modern civilization has come in recent decades into a new phase in its development, called the information society. The concept of "information society" has become one of the most common. Therefore, the attempt to understand what exactly the society we live in, what are its essential features, and possible future scenarios, is important to the social and philosophical analysis. At the heart of all these deep transformations is more increasing, almost defining role knowledge and information as play substrata of «information society». The mankind opened for itself and actively exploits a new resource – information. Information society puts forward on the arena new type of the power, at the heart of which activity – mastering by a new resource: information and knowledge. The password of the new power – intelligence as synthesis of knowledge, information and communications, the strength of mind, fundamental sociocultural values. In a postindustrial society, the power of knowledge and information is crucial in the management of the company, pushing into the background the influence of money and state coercion.
Abstract: Isobaric vapor-liquid equilibrium measurements are
reported for binary mixture of 2-Methyltetrahydrofuran and Cumene
at 97.3 kPa. The data were obtained using a vapor recirculating type
(modified Othmer's) equilibrium still. The mixture shows slight
negative deviation from ideality. The system does not form an
azeotrope. The experimental data obtained in this study are
thermodynamically consistent according to the Herington test. The
activity coefficients have been satisfactorily correlated by means of
the Margules, and NRTL equations. Excess Gibbs free energy has
been calculated from the experimental data. The values of activity
coefficients have also been obtained by the UNIFAC group
contribution method.
Abstract: Today many countries have the ambitious purposes of long-term and continuous development: constant growth of competitiveness, maintenance of a high standard of living of the population, leadership in the world market. One of the best possible ways of achievement of these purposes is a transition of the countries to innovative economy. The paper presents the analyses of problems of forming of innovative receptivity to innovations and creation of «innovative society». Creation of an innovative culture in a society and increase of the level of prestige of innovative activity are the best ways of developing of innovative processes. The base of the analysis is a comparing of Russia and different developed countries according to the level of some indictors of innovative activity.1
Abstract: A series of 1-(1H-benzimidazol-2-yl)-3-(substituted phenyl)-2-propen-1-one were allowed to react with hydrazine hydrate and phenyl hydrazine in submitted reactions to get pyrazoline and phenyl pyrazoline derivatives. All the compounds entered for screening at the Tuberculosis Antimicrobial Acquisition and Coordinating Facility (TAACF) for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv strain (ATCC 27294) using Microplate Alamar Blue Assay (MABA) susceptibility test. The results expressed as MIC (minimum inhibitory concentration) in μg/mL. Among the fifteen compounds, eight compounds were found to have MIC values less than 10 μg/mL. These were subjected for cytotoxicity assay in VERO cells to determine CC50 (cytotoxic concentration 50%) values and finally SI (Selectivity Index) were calculated. Compound (XV) 2-[5-(4- fluorophenyl)-1-phenyl-4,5-dihydro-1H-3-pyrazolyl]-1Hbenzimidazole was considered the best candidate of the series that could be a good starting point to develop new lead compounds in the fight against tuberculosis.
Abstract: Qualification of doctoral students- and the candidates for a scientific degree is evaluated by the ability to solve scientific ideas in an innovative way, consequently, being a potential of research and science they play a significant role in the sustainability context of the society. The article deals with the analysis of the results of the pilot project, the aim of which has been to study the structure of doctoral students- research competences in the sustainability context. With the existance of variety of theories on research competence development, their analysis focuses on the attained aim approach. Three competence groups have been identified in this study: informative, communicative and instrumental. Within the study the doctoral students and candidates for a scientific degree (N=64) made their self-assessment of research competences. The study results depict their present research competence development level and its dynamics according to the aim to attain.
Abstract: Environmental considerations have become an integral part of developmental thinking and decision making in many countries. It is growing rapidly in importance as a discipline of its own. Preventive approaches have been used at the evolutional process of environmental management as a broad and dynamic system for dealing with pollution and environmental degradation. In this regard, Environmental Assessment as an activity for identification and prediction of project’s impacts carried out in the world and its legal significance dates back to late 1960. In Iran, according to the Article 2 of Environmental Protection Act, Environmental Impact Assessment (EIA) should be prepared for seven categories of project. This article has been actively implementing by Department of Environment at 1997. World Bank in 1989 attempted to introducing application of Environmental Assessment for making decision about projects which are required financial assistance in developing countries. So, preparing EIA for obtaining World Bank loan was obligated. Alborz Project is one of the World Bank Projects in Iran which is environmentally significant. Seven out of ten W.B safeguard policies were considered at this project. In this paper, Alborz project, objectives, safeguard policies and role of environmental management will be elaborated
Abstract: The present study is concerned with the absorption
center of photophoresis within a micro-sized and spheroidal particle in
a gaseous medium. A particle subjected to an intense light beam can
absorb electromagnetic energy within the particle unevenly, which
results in photophoretic force to drive the particle in motion. By
evaluating the energy distribution systematically at various conditions,
the study focuses on the effects of governing parameters, such as
particle aspect ratio, size parameter, refractivity, and absorptivity, on
the heat source function within the particle and their potential
influences to the photophoresis.
Abstract: Oral health is particular important to the hospitalized
patients with chronic schizophrenia for an extreme high potential of the respiratory infections. Due to the degeneration of physical capability, patients of this kind typically fall dependent in the activity of daily living (ADL). A very high percentage of patients had dental
problems of which mostly could be easily avoid by easy regular tooth brushing. Purpose of the project is to develop a mechanism in helping the schizophrenia patients in rebuilding a tooth-cleaning habit. The
project observed and evaluated the tooth-cleaning behavior of 100
male patients in a psychiatric hospital, and found the majority of them
ignored such an activity in a three-month period of time. In the meantime, the primary care-givers were not aware or not convinced
the importance of such a need of dental hygiene, and thus few if any
tooth cleaning training or knowledge on dental hygiene were given to
the patients. The project then developed a program based on the numerous observations and discussions. The improvement program
included patients- group education, care-givers- training, and a
tool-kit for tooth-brush holding was erected. The project launched
with some incentive package. The outcomes were encouraging with
87% of the patients had rebuilt their tooth-brushing habits against
previous 22%, and the tooth cleaning kits were 100% kept against 22%
in the past. This project had significantly improved the oral health of
the patients. The project, included the procedure and the tool-kit
holder specific for this purpose, was a good examples for psychiatric
hospitals.
Abstract: The gamma radiation in samples of a variety of
natural tiling rocks (granites) produced and imported in Iran use in
the building industry was measured, employing high-resolution
Gamma-ray spectroscopy. The rock samples were pulverized, sealed
in 0.5 liter plastic Marinelli beakers, and measured in the laboratory
with an accumulating time between 50000 and 80000 second each.
From the measured Gamma-ray spectra, activity concentrations were
determined for 232Th (range from 6.5 to 172.2 Bq kg-1), 238U (from
7.5 to 178.1 Bq kg-1 ),226Ra( from 3.8 to 94.2 Bq kg-1 ) 40K (from
556.9 to 1539.2 Bq kg-1). From the 29 samples measured in this
study, “Nehbndan ( Berjand )" appears to present the highest
concentrations for 232Th,“Big Red Flower (China) "for 238U , “
Khoram dareh" for 226 Ra and “ Peranshahr" for 40K , respectively.
Abstract: Lutein is a dietary oxycarotenoid which is found
to reduce the risks of Age-related Macular Degeneration
(AMD). Supercritical fluid extraction of lutein esters from
marigold petals was carried out and was found to be much
effective than conventional solvent extraction. The
saponification of pre-concentrated lutein esters to produce free
lutein was studied which showed a composition of about 88%
total carotenoids (UV-VIS spectrophotometry) and 90.7%
lutein (HPLC). The lipase catalyzed hydrolysis of lutein esters
in conventional medium was investigated. The optimal
temperature, pH, enzyme concentration and water activity
were found to be 50°C, 7, 15% and 0.33 respectively and the
activity loss of lipase was about 25% after 8 times re-use in at
50°C for 12 days. However, the lipase catalyzed hydrolysis of
lutein esters in conventional media resulted in poor
conversions (16.4%).
Abstract: Although Face detection is not a recent activity in the
field of image processing, it is still an open area for research. The
greatest step in this field is the work reported by Viola and its recent
analogous is Huang et al. Both of them use similar features and also
similar training process. The former is just for detecting upright
faces, but the latter can detect multi-view faces in still grayscale
images using new features called 'sparse feature'. Finding these
features is very time consuming and inefficient by proposed methods.
Here, we propose a new approach for finding sparse features using a
genetic algorithm system. This method requires less computational
cost and gets more effective features in learning process for face
detection that causes more accuracy.
Abstract: The amounts of radioactivity in the igneous rocks
have been investigated; samples were collected from the total of eight
basalt rock types in the northeastern of Kurdistan region/Iraq. The
activity concentration of 226Ra (238U) series, 228Ac (232Th) series, 40K
and 137Cs were measured using Planar HPGe and NaI(Tl) detectors.
Along the study area the radium equivalent activities Raeq in Bq/Kg
of samples under investigation were found in the range of 22.16 to
77.31 Bq/Kg with an average value of 44.8 Bq/Kg, this value is much
below the internationally accepted value of 370 Bq/Kg. To estimate
the health effects of this natural radioactive composition, the average
values of absorbed gamma dose rate D (55 nGyh-1), Indoor and
outdoor annual effective dose rates Eied (0.11 mSvy-1) . and Eoed
(0.03 mSvy-1), External hazard index Hex (0.138) and internal hazard
index Hin(0.154), and representative level index Iγr (0.386) have been
calculated and found to be lower than the worldwide average values.
Abstract: Given that entrepreneurship is a very significant factor of regional development, it is necessary to approach systematically the development with measures of regional politics. According to international classification The Nomenclature of Territorial Units for Statistics (NUTS II), there are three regions in Croatia. The indicators of entrepreneurial activities on the national level of Croatia are analyzed in the paper, taking into consideration the results of referent research. The level of regional development is shown based on the analysis of entrepreneurs- operations. The results of the analysis show a very unfavorable situation in entrepreneurial activities on the national level of Croatia. The origin of this situation is to be found in the surroundings with an expressed inequality of regional development, which is caused by the non-existence of a strategically directed regional policy. In this paper recommendations which could contribute to the reduction of regional inequality in Croatia, have been made.
Abstract: The aim of present study was to assess the effect of
glucogenic (G) and lipogenic (L) diets on blood metabolites in
Baloochi lambs. Three rumen cannulated Baloochi sheep were used
as a 3×3 Latin square design with 3 periods (28 days). Experimental
diets were a glucogenic, a lipogenic and a mixture of G and L diets
(50:50). The animals were fed diets consisted of 50% chopped alfalfa
hay and 50% concentrate. Diets were fed once daily ad libitum.
Blood samples were taken from jugular vein before the feeding, 2, 4
and 6 hour post feeding at day 27. Results indicated that β-
hydroxybutyrate (BHBA), glucose, insulin and aspartate
aminotransferase (AST) were not affected by treatments (P > 0.05).
However, lipogenic diet increased significantly activity of Alanine
aminotransferase (ALT) and concentration of non-esterified fatty acid
(NEFA) in blood plasma (P < 0.05)
Abstract: In this study, production possibilities of hydrogen and/or methane via SCWG from black grape residues have been investigated. For this aim, grape residues which remain as a byproduct of the wine making process have been used. Since utilization from grape residues is limited due to the high moisture content, supercritical water gasification is the most convenient method. The effect of the gasification temperature and type of catalyst on supercritical water gasification have been investigated. Gasification experiments were performed in a batch autoclave at four different temperatures 300, 400, 500 and 600°C. K2CO3 and Trona (NaHCO3.Na2CO3·2H2O) were used as catalyst. Real biomass types of black grape residues have been successfully gasified and the product gas (hydrogen, methane, carbon dioxide, carbon monoxide and a small amount of ethane and ethylene) were identified by using gas chromatography. A TOC analyzer was used to determine total organic carbon (TOC) content of aqueous phase. The amounts of carboxylic acids, aldehydes, ketones, furfurals and phenols present in the aqueous solutions were analyzed by high performance liquid chromatography. When the temperature increased from 300°C to 600°C, mol% of H2 in gas products increased. The presence of catalysts improves the hydrogen yield. Trona showed gasification activity to be similar to that of K2CO3. It may be concluded that the use of Trona instead of commercially produced catalysts, can be preferably used in the gasification of biomass in supercritical water.