Abstract: The right to housing is a basic need while good
quality and affordable housing is a reflection of a high quality of life.
However, housing remains a major problem for most, especially for
the bottom billions. Satisfaction on housing and neighbourhood
conditions are one of the important indicators that reflect quality of
life. These indicators are also important in the process of evaluating
housing policy with the objective to increase the quality of housing
and neighbourhood. The research method is purely based on a
quantitative method, using a survey. The findings show that housing
purchasing trend in urban Malaysia is determined by demographic
profiles, mainly by education level, age, gender and income. The
period of housing ownership also influenced the socio-cultural
interactions and satisfaction of house owners with their
neighbourhoods. The findings also show that the main concerns for
house buyers in urban areas are price and location of the house.
Respondents feel that houses in urban Malaysia is too expensive and
beyond their affordability. Location of houses and distance from
work place are also regarded as the main concern. However,
respondents are fairly satisfied with religious and socio-cultural
facilities in the housing areas and most importantly not many regard
ethnicity as an issue in their decision-making, when buying a house.
Abstract: Mechanical interaction between endothelial cells (ECs) and the extracellular matrix (or collagen gel) is known to influence the sprouting response of endothelial cells during angiogenesis. This influence is believed to impact on the capability of endothelial cells to sense soluble chemical cues. Quantitative analysis of endothelial-cell-mediated displacement of the collagen gel provides a means to explore this mechanical interaction. Existing analysis in this context is generally limited to 2D settings. In this paper, we investigate the mechanical interaction between endothelial cells and the extracellular matrix in terms of the endothelial-cellmediated displacement of the collagen gel in both 2D and 3D. Digital image correlation and Digital volume correlation are applied on confocal reflectance image stacks to analyze cell-mediated displacement of the gel. The skeleton of the sprout is extracted from phase contrast images and superimposed on the displacement field to further investigate the link between the development of the sprout and the displacement of the gel.
Abstract: Multi-agent system is composed by several agents
capable of reaching the goal cooperatively. The system needs an agent
platform for efficient and stable interaction between intelligent agents.
In this paper we propose a flexible and scalable agent platform by
composing the containers with multiple hierarchical agent groups. It
also allows efficient implementation of multiple domain presentations
of the agents unlike JADE. The proposed platform provides both
group management and individual management of agents for
efficiency. The platform has been implemented and tested, and it can
be used as a flexible foundation of the dynamic multi-agent system
targeting seamless delivery of ubiquitous services.
Abstract: Herein, we report the different types of surface morphology due to the interaction between the pure protein Insulin (INS) and catanionic surfactant mixture of Sodium Dodecyl Sulfate (SDS) and Cetyl Trimethyl Ammonium Bromide (CTAB) at air/water interface obtained by the Langmuir-Blodgett (LB) technique. We characterized the aggregations by Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM) and Fourier transform infrared spectroscopy (FTIR) in LB films. We found that the INS adsorption increased in presence of catanionic surfactant at air/water interface. The presence of small amount of surfactant induces two-stage growth kinetics due to the pure protein absorption and protein-catanionic surface micelle interaction. The protein remains in native state in presence of small amount of surfactant mixture. Smaller amount of surfactant mixture with INS is producing surface micelle type structure. This may be considered for drug delivery system. On the other hand, INS becomes unfolded and fibrillated in presence of higher amount of surfactant mixture. In both the cases, the protein was successfully immobilized on a glass substrate by the LB technique. These results may find applications in the fundamental science of the physical chemistry of surfactant systems, as well as in the preparation of drug-delivery system.
Abstract: This paper describes a method of modeling to model
shadow play puppet using sophisticated computer graphics techniques
available in OpenGL in order to allow interactive play in real-time
environment as well as producing realistic animation. This paper
proposes a novel real-time method is proposed for modeling of puppet
and its shadow image that allows interactive play of virtual shadow
play using texture mapping and blending techniques. Special effects
such as lighting and blurring effects for virtual shadow play
environment are also developed. Moreover, the use of geometric
transformations and hierarchical modeling facilitates interaction
among the different parts of the puppet during animation. Based on the
experiments and the survey that were carried out, the respondents
involved are very satisfied with the outcomes of these techniques.
Abstract: Cross sections of As radionuclides in the interaction of natGe with 14-30 MeV protons have been deduced by off-line y-ray spectroscopy to find optimal reaction channels leading to radiotracers for positron emission tomography. The experimental results were compared with the previous results and those estimated by the compound nucleus reaction model.
Abstract: An implant elicits a biological response in the
surrounding tissue which determines the acceptance and long-term
function of the implant. Dental implants have become one of the
main therapy methods in clinic after teeth lose. A successful implant
is in contact with bone and soft tissue represent by fibroblasts. In our
study we focused on the interaction between six different chemically
and physically modified titanium implants (Tis-MALP, Tis-O, Tis-
OA, Tis-OPAAE, Tis-OZ, Tis-OPAE) with alveolar fibroblasts as
well as with five type of microorganisms (S. epidermis, S.mutans, S.
gordonii, S. intermedius, C.albicans). The analysis of microorganism
adhesion was determined by CFU (colony forming unite) and biofilm
formation. The presence of α3β1 and vinculin expression on alveolar
fibroblasts was demonstrated using phospho specific cell based
ELISA (PACE). Alveolar fibroblasts have the highest expression of
these proteins on Tis-OPAAE and Tis-OPAE. It corresponds with
results from bacterial adhesion and biofilm formation and it was
related to the lowest production of collagen I by alveolar fibroblasts
on Tis-OPAAE titanium disc.
Abstract: The objective of the present study was to determine
the effect of different concentration of spermatozoa and length of
storage in 5 0C on sperm motility. Semen was collected using
artificial vagina from goat aged 2 to 2.5 years. Fresh goat semen
with sperm motility ≥ 70% was used as material. Semen was
divided into 4 treatments of concentration (40 x 10 6 / ml, 50 x
106/ml, 60x106/ml, 70x106/ml) with length of storage 0,12,24,36 h. in
5 0C. There were interactions (P
Abstract: Dynamic Causal Modeling (DCM) functional
Magnetic Resonance Imaging (fMRI) is a promising technique to
study the connectivity among brain regions and effects of stimuli
through modeling neuronal interactions from time-series
neuroimaging. The aim of this study is to study characteristics of a
mirror neuron system (MNS) in elderly group (age: 60-70 years old).
Twenty volunteers were MRI scanned with visual stimuli to study a
functional brain network. DCM was employed to determine the
mechanism of mirror neuron effects. The results revealed major
activated areas including precentral gyrus, inferior parietal lobule,
inferior occipital gyrus, and supplementary motor area. When visual
stimuli were presented, the feed-forward connectivity from visual
area to conjunction area was increased and forwarded to motor area.
Moreover, the connectivity from the conjunction areas to premotor
area was also increased. Such findings can be useful for future
diagnostic process for elderly with diseases such as Parkinson-s and
Alzheimer-s.
Abstract: Experiments have been carried out at sub-critical
Reynolds number to investigate free-to-roll motions induced by
forebody and/or wings complex flow on a 30° swept back nonslender
wings-slender body-model for static and dynamic (pitch-up)
cases. For the dynamic (pitch-up) case it has been observed that roll
amplitude decreases and lag increases with increase in pitching
speed. Decrease in roll amplitude with increase in pitch rate is
attributed to low disturbing rolling moment due to weaker interaction
between forebody and wing flow components. Asymmetric forebody
vortices dominate and control the roll motion of the model in
dynamic case when non-dimensional pitch rate ≥ 1x10-2.
Effectiveness of the active control scheme utilizing rotating nose with
artificial tip perturbation is observed to be low in the angle of attack
region where the complex flow over the wings has contributions from
both forebody and wings.
Abstract: Transcription factors are a group of proteins that
helps for interpreting the genetic information in DNA.
Protein-protein interactions play a major role in the execution
of key biological functions of a cell. These interactions are
represented in the form of a graph with nodes and edges.
Studies have showed that some nodes have high degree of
connectivity and such nodes, known as hub nodes, are the
inevitable parts of the network. In the present paper a method
is proposed to identify hub transcription factor proteins using
sequence information. On a complete data set of transcription
factor proteins available from the APID database, the
proposed method showed an accuracy of 77%, sensitivity of
79% and specificity of 76%.
Abstract: carbonylation of methanol in homogenous phase is
one of the major routesfor production of acetic acid. Amongst group
VIII metal catalysts used in this process iridium has displayed the
best capabilities. To investigate effect of operating parameters like:
temperature, pressure, methyl iodide, methyl acetate, iridium,
ruthenium, and water concentrations on the reaction rate,
experimental design for this system based upon central composite
design (CCD) was utilized. Statistical rate equation developed by this
method contained individual, interactions and curvature effects of
parameters on the reaction rate. The model with p-value less than
0.0001 and R2 values greater than 0.9; confirmeda satisfactory fitness
of the experimental and theoretical studies. In other words, the
developed model and experimental data obtained passed all
diagnostic tests establishing this model as a statistically significant.
Abstract: A numerical method is developed for simulating
the motion of particles with arbitrary shapes in an effectively
infinite or bounded viscous flow. The particle translational and
angular motions are numerically investigated using a fluid-structure
interaction (FSI) method based on the Arbitrary-Lagrangian-Eulerian
(ALE) approach and the dynamic mesh method (smoothing and
remeshing) in FLUENT ( ANSYS Inc., USA). Also, the effects of
arbitrary shapes on the dynamics are studied using the FSI method
which could be applied to the motions and deformations of a single
blood cell and multiple blood cells, and the primary thrombogenesis
caused by platelet aggregation. It is expected that, combined with a
sophisticated large-scale computational technique, the simulation
method will be useful for understanding the overall properties of blood
flow from blood cellular level (microscopic) to the resulting
rheological properties of blood as a mass (macroscopic).
Abstract: Selection of maize (Zea mays) hybrids with wide adaptability across diverse farming environments is important, prior to recommending them to achieve a high rate of hybrid adoption. Grain yield of 14 maize hybrids, tested in a randomized completeblock design with four replicates across 22 environments in Iran, was analyzed using site regression (SREG) stability model. The biplot technique facilitates a visual evaluation of superior genotypes, which is useful for cultivar recommendation and mega-environment identification. The objectives of this study were (i) identification of suitable hybrids with both high mean performance and high stability (ii) to determine mega-environments for maize production in Iran. Biplot analysis identifies two mega-environments in this study. The first mega-environments included KRM, KSH, MGN, DZF A, KRJ, DRB, DZF B, SHZ B, and KHM, where G10 hybrid was the best performing hybrid. The second mega-environment included ESF B, ESF A, and SHZ A, where G4 hybrid was the best hybrid. According to the ideal-hybrid biplot, G10 hybrid was better than all other hybrids, followed by the G1 and G3 hybrids. These hybrids were identified as best hybrids that have high grain yield and high yield stability. GGE biplot analysis provided a framework for identifying the target testing locations that discriminates genotypes that are high yielding and stable.
Abstract: Recent years have seen a growing trend towards the
integration of multiple information sources to support large-scale
prediction of protein-protein interaction (PPI) networks in model
organisms. Despite advances in computational approaches, the
combination of multiple “omic" datasets representing the same type
of data, e.g. different gene expression datasets, has not been
rigorously studied. Furthermore, there is a need to further investigate
the inference capability of powerful approaches, such as fullyconnected
Bayesian networks, in the context of the prediction of PPI
networks. This paper addresses these limitations by proposing a
Bayesian approach to integrate multiple datasets, some of which
encode the same type of “omic" data to support the identification of
PPI networks. The case study reported involved the combination of
three gene expression datasets relevant to human heart failure (HF).
In comparison with two traditional methods, Naive Bayesian and
maximum likelihood ratio approaches, the proposed technique can
accurately identify known PPI and can be applied to infer potentially
novel interactions.
Abstract: Autism Spectrum Disorder (ASD) is a pervasive developmental disorder which affects individuals with varying degrees of impairment. Currently, there has been ample research done in serious game for autism children. Although serious games are traditionally associated with software developments, developing them in the autism field involves studying the associated technology and paying attention to aspects related to interaction with the game. Serious Games for autism cover matters related to education, therapy for communication, psychomotor treatment and social behavior enhancement. In this paper, a systematic review sets out the lines of development and research currently being conducted into serious games which pursue some form of benefit in the field of autism. This paper includes a literature review of relevant serious game developments since in year 2007 and examines new trends.
Abstract: Identifying the nature of protein-nanoparticle
interactions and favored binding sites is an important issue in
functional characterization of biomolecules and their physiological
responses. Herein, interaction of silver nanoparticles with lysozyme
as a model protein has been monitored via fluorescence spectroscopy.
Formation of complex between the biomolecule and silver
nanoparticles (AgNPs) induced a steady state reduction in the
fluorescence intensity of protein at different concentrations of
nanoparticles. Tryptophan fluorescence quenching spectra suggested
that silver nanoparticles act as a foreign quencher, approaching the
protein via this residue. Analysis of the Stern-Volmer plot showed
quenching constant of 3.73 μM−1. Moreover, a single binding site in
lysozyme is suggested to play role during interaction with AgNPs,
having low affinity of binding compared to gold nanoparticles.
Unfolding studies of lysozyme showed that complex of lysozyme-
AgNPs has not undergone structural perturbations compared to the
bare protein. Results of this effort will pave the way for utilization of
sensitive spectroscopic techniques for rational design of
nanobiomaterials in biomedical applications.
Abstract: While many studies have conducted the achievement
gap between groups of students in school districts, few studies have
utilized resilience research to investigate achievement gaps within
classrooms. This paper aims to summarize and discuss some recent
studies Waxman, Padr├│n, and their colleagues conducted, in which
they examined learning environment differences between resilient
and nonresilient students in reading and mathematics classrooms.
The classes consist of predominantly Hispanic elementary school
students from low-income families. These studies all incorporated
learning environment questionnaires and systematic observation
methods. Significant differences were found between resilient and
nonresilient students on their classroom learning environments and
classroom behaviors. The observation results indicate that the amount
and quality of teacher and student academic interaction are two of the
most influential variables that promote student outcomes. This paper
concludes by suggesting the following teacher practices to promote
resiliency in schools: (a) using feedback from classroom observation
and learning environment measures, (b) employing explicit teaching
practices; and (c) understanding students on a social and personal
level.
Abstract: Bovine viral diarrhea virus (BVDV) can cause lifelong
persistent infection. One reason for the phenomena is attributed to
BVDV infection to placenta tissue. However the mechanisms that
BVDV invades into placenta tissue remain unclear. To clarify the
molecular mechanisms, we investigated the possible means that
BVDV entered into bovine trophoblast cells (TPC). Yeast two-hybrid
system was used to identify proteins extracted from TPC, which
interact with BVDV envelope glycoprotein E2. A PGbkt7-E2 yeast
expression vector and TPC cDNA library were constructed. Through
two rounds of screening, three positive clones were identified.
Sequencing analysis indicated that all the three positive clones
encoded the same protein clathrin. Physical interaction between
clathrin and BVDV E2 protein was further confirmed by
coimmunoprecipitation experiments. This result suggested that the
clathrin might play a critical role in the process of BVDV entry into
placenta tissue and might be a novel antiviral target for preventing
BVDV infection.
Abstract: The new framework the Higher Education is
immersed in involves a complete change in the way lecturers must
teach and students must learn. Whereas the lecturer was the main
character in traditional education, the essential goal now is to
increase the students' participation in the process. Thus, one of the
main tasks of lecturers in this new context is to design activities of
different nature in order to encourage such participation. Seminars
are one of the activities included in this environment. They are active
sessions that enable going in depth into specific topics as support of
other activities. They are characterized by some features such as
favoring interaction between students and lecturers or improving
their communication skills. Hence, planning and organizing strategic
seminars is indeed a great challenge for lecturers with the aim of
acquiring knowledge and abilities. This paper proposes a method
using Artificial Intelligence techniques to obtain student profiles
from their marks and preferences. The goal of building such profiles
is twofold. First, it facilitates the task of splitting the students into
different groups, each group with similar preferences and learning
difficulties. Second, it makes it easy to select adequate topics to be a
candidate for the seminars. The results obtained can be either a
guarantee of what the lecturers could observe during the development
of the course or a clue to reconsider new methodological strategies in
certain topics.