Abstract: Osteoporosis is a complex health disease characterized by low bone mineral density, which is determined by an interaction of genetics with metabolic and environmental factors. Current research in genetics of osteoporosis is focused on identification of responsible genes and polymorphisms. TNFRSF11B gene plays a key role in bone remodeling. The aim of this study was to investigate the genotype and allele distribution of A163G (rs3102735) osteoprotegerin gene promoter and G1181C (rs2073618) osteoprotegerin first exon polymorphisms in the group of 180 unrelated postmenopausal women with diagnosed osteoporosis and 180 normal controls. Genomic DNA was isolated from peripheral blood leukocytes using standard methodology. Genotyping for presence of different polymorphisms was performed using the Custom Taqman®SNP Genotyping assays. Hardy-Weinberg equilibrium was tested for each SNP in the groups of participants using the chi-square (χ2) test. The distribution of investigated genotypes in the group of patients with osteoporosis were as follows: AA (66.7%), AG (32.2%), GG (1.1%) for A163G polymorphism; GG (19.4%), CG (44.4%), CC (36.1%) for G1181C polymorphism. The distribution of genotypes in normal controls were follows: AA (71.1%), AG (26.1%), GG (2.8%) for A163G polymorphism; GG (22.2%), CG (48.9%), CC (28.9%) for G1181C polymorphism. In A163G polymorphism the variant G allele was more common among patients with osteoporosis: 17.2% versus 15.8% in normal controls. Also, in G1181C polymorphism the phenomenon of more frequent occurrence of C allele in the group of patients with osteoporosis was observed (58.3% versus 53.3%). Genotype and allele distributions showed no significant differences (A163G: χ2=0.270, p=0.605; χ2=0.250, p=0.616; G1181C: χ2= 1.730, p=0.188; χ2=1.820, p=0.177). Our results represents an initial study, further studies of more numerous file and associations studies will be carried out. Knowing the distribution of genotypes is important for assessing the impact of these polymorphisms on various parameters associated with osteoporosis. Screening for identification of “at-risk” women likely to develop osteoporosis and initiating subsequent early intervention appears to be most effective strategy to substantially reduce the risks of osteoporosis.
Abstract: This paper presents an extraction of maximum energy from Solar Photovoltaic Array (SPVA) under partial shaded conditions by optimum selection of array size using Particle Swarm Optimization (PSO) technique. In this paper a detailed study on the output reduction of different SPVA configurations under partial shaded conditions have been carried out. A generalized MATLAB M-code based software model has been used for any required array size, configuration, shading patterns and number of bypass diodes. Comparative study has been carried out on different configurations by testing several shading scenarios. While the number of shading patterns and the rate of change are very low for stationary SPVA but these may be quite large for SPVA mounted on a mobile platforms. This paper presents the suitability of PSO technique to select optimum configuration for mobile arrays by calculating the global peak (GP) of different configurations and to transfer maximum power to the load.
Abstract: This paper investigates the performance of the single TCSC and proposed split TCSC on transmission system where India’s first TCSC project is installed in Kanpur - Ballabhgarh (KB) line to ensure the fine tuning of line reactance by proposed split TCSC in place of existing KB TCSC. A three phase KB transmission system is developed in MATLAB/Simulink (SimPowerSystems) for
without any compensation,
with fixed capacitor (FC),
with FC + existing KB TCSC and
with FC + proposed split TCSC
The KB system is analyzed for a step variation of load and performance of the system is investigated with a closed loop reactance control method.
Abstract: Artificial neural networks (ANN) are used in distinct researching fields and professions, and are prepared by cooperation of scientists in different fields such as computer engineering, electronic, structure, biology and so many different branches of science. Many models are built correlating the parameters and the outputs in electrical discharge machining (EDM) concern for different types of materials. Up till now model for Ti-5Al-2.5Sn alloy in the case of electrical discharge machining performance characteristics has not been developed. Therefore, in the present work, it is attempted to generate a model of material removal rate (MRR) for Ti-5Al-2.5Sn material by means of Artificial Neural Network. The experimentation is performed according to the design of experiment (DOE) of response surface methodology (RSM). To generate the DOE four parameters such as peak current, pulse on time, pulse off time and servo voltage and one output as MRR are considered. Ti-5Al-2.5Sn alloy is machined with positive polarity of copper electrode. Finally the developed model is tested with confirmation test. The confirmation test yields an error as within the agreeable limit. To investigate the effect of the parameters on performance sensitivity analysis is also carried out which reveals that the peak current having more effect on EDM performance.
Abstract: Upper gastrointestinal endoscopy is a commonly performed diagnostic and therapeutic procedure and has many adverse effects like cardiopulmonary complications, complications related to sedation, infectious complications, bleeding and perforation. So this study was undertaken to evaluate important variables like patient’s age, gender and stage of the procedure in relation to the cardiopulmonary changes during diagnostic upper gastrointestinal endoscopy by monitoring oxygen saturation, blood pressure, heart rate and electrocardiogram. This is a prospective longitudinal hospital based study involving a total of 140 consecutive patients, at Sri. B. M. Patil Medical College, Hospital and Research Centre. Cardiopulmonary changes during upper gastrointestinal endoscopy are more common in the age groups of 51-60 years, with equal frequency in both male and female. Oxygen saturation levels decreased by about 4% in both sexes during introduction of endoscopy. Mild to moderate hypoxia was found in 32% of the study group. Severe hypoxia was found in 5% of the patients, mostly in those patients who are above 50 years of age. Tachycardia was noted in 88% of the study group patients. Blood pressure increased to hypertension levels in 22 patients (15.7%) which returned to normal within few minutes after the procedure. S-T depression was noticed in 4% of patients and T wave inversion in 8% of patients during upper gastrointestinal endoscopy. All these changes disappeared after 10 minutes after the endoscopy. Cardiopulmonary changes are common during upper gastrointestinal endoscopy. Maximum changes in oxygen saturation, heart rate and blood pressure occurred immediately after the introduction of endoscope. The cardiopulmonary changes did not manifest into any identifiable clinical symptoms. The rate of recovery was faster in younger age groups and women.
Abstract: This paper investigates the possibility of improving throughputs of some Media Access Controls protocols such as ALOHA, slotted ALOHA and Carrier Sense Multiple Access with Collision Avoidance with the aim of increasing the performance of Powerline access networks. In this investigation, the real Powerline network topology in Tanzania located in Dar es Salaam City, Kariakoo area was used as a case study. During this investigation, Wireshark Network Protocol Analyzer was used to analyze data traffic of similar existing network for projection purpose and then the data were simulated using MATLAB. This paper proposed and analyzed three improvement techniques based on collision domain, packet length and combination of the two. From the results, it was found that the throughput of Carrier Sense Multiple Access with Collision Avoidance protocol improved noticeably while ALOHA and slotted ALOHA showed insignificant changes especially when the hybrid techniques were employed.
Abstract: Coverage conservation and extend the network lifetime are the primary issues in wireless sensor networks. Due to the large variety of applications, coverage is focus to a wide range of interpretations. The applications necessitate that each point in the area is observed by only one sensor while other applications may require that each point is enclosed by at least sensors (n>1) to achieve fault tolerance. Sensor scheduling activities in existing Transparent and non- Transparent relay modes (T-NT) Mobile Multi-Hop relay networks fails to guarantee area coverage with minimal energy consumption and fault tolerance. To overcome these issues, Cluster based Energy Competent n- coverage scheme called (CEC n-coverage scheme) to ensure the full coverage of a monitored area while saving energy. CEC n-coverage scheme uses a novel sensor scheduling scheme based on the n-density and the remaining energy of each sensor to determine the state of all the deployed sensors to be either active or sleep as well as the state durations. Hence, it is attractive to trigger a minimum number of sensors that are able to ensure coverage area and turn off some redundant sensors to save energy and therefore extend network lifetime. In addition, decisive a smallest amount of active sensors based on the degree coverage required and its level. A variety of numerical parameters are computed using ns2 simulator on existing (T-NT) Mobile Multi-Hop relay networks and CEC n-coverage scheme. Simulation results showed that CEC n-coverage scheme in wireless sensor network provides better performance in terms of the energy efficiency, 6.61% reduced fault tolerant in terms of seconds and the percentage of active sensors to guarantee the area coverage compared to exiting algorithm.
Abstract: The aim of this research was to create collaborative learning activities in the course of Principles of Mathematics for graduate level by investigating the students’ ability in proving the mathematics principles as well as their attitudes towards the activities. The samples composed of 2 main group; lecturers and students. The lecturers consisted of 3 teachers who taught the course of Principles of Mathematics at Rajabhat Suan Sunandha Unicersity in the academic year 2012. The students consisted of 32 students joining the cooperative learning activities in the subject of Principles of Mathematics in the academic year 2012. The research tools included activity plan for cooperative learning, testing on mathematics with the reliability of 0.8067 and the attitude questionnaires reported by the students. The results showed that: 1) the efficiency of the developed cooperative learning activities was 69.76/ 68.57 which was lower than the set criteria at 70/70. 2) The students joining the cooperative learning activities were able to prove the principles of mathematics at the average of 70%. 3) The students joining the cooperative learning activities reported moderate attitude towards the activities.
Abstract: The Salman Farsi dam project is constructed on the Ghareh Agahaj River about 140km south of Shiraz city in the Zagros Mountains of southwestern Iran. This tectonic province of south-western Iran is characterized by a simple folded sedimentary sequence. The dam foundation rocks compose of the Asmari Formation of Oligo-miocene and generally comprise of a variety of karstified carbonate rocks varying from strong to weak rocks. Most of the rocks exposed at the dam site show a primary porosity due to incomplete diagenetic recrystallization and compaction. In addition to these primary dispositions to weathering, layering conditions (frequency and orientation of bedding) and the subvertical tectonic discontinuities channeled preferably the infiltrating by deep-sited hydrothermal solutions. Consequently the porosity results to be enlarged by dissolution and the rocks are expected to be karstified and to develop cavities in correspondence of bedding, major joint planes and fault zones. This kind of karsts is named hypogenic karsts which associated to the ascendant warm solutions. Field observations indicate strong karstification and vuggy intercalations especially in the middle part of the Asmari succession. The biggest karst in the dam axis which identified by speleological investigations is Golshany Cave with volume of about 150,000 m3. The tendency of the Asmari limestone for strong dissolution can alert about the seepage from the reservoir and area of the dam locality.
Abstract: In most of apparel creation, the designer usually uses standard pattern as a fundamental of pattern making. In the design of each kind of apparel, standard pattern is starting point of production. The importance of standard pattern is that it is able to have the apparel fits to general people. Therefore, standard pattern is standardized to be the same. Regardless which type of apparel, its standard pattern will have similar production. Anyhow, the author sees that the apparel design, regardless for which type of apparel, has to stick on the standard pattern as a fundamental of apparel design and this seems to be a limitation of apparel design without any designing alternative being developed. In the research on the creation of contemporary apparel Inspired by the sofa’s pattern structure in Vimanmek Mansion. The author has applied the pattern of the sofa and armchair to be the principle in the apparel design, instead of standard pattern, to create new form of structures and shapes making the contemporary apparel becomes more interesting and different than previous, can be used in daily life, as well as being a new alternative for apparel design. Those who are interesting in such idea can apply and develop it to be more variety further.
Abstract: The speed profiles, gas holdup (eG) and global oxygen transfer coefficient (kLa) from a stirred airlift bioreactor using water as the fluid model, was investigated by computational fluid dynamics modeling. The parameters predicted by the computer model were validated with the experimental dates. The CFD results were very close to those obtained experimentally. During the simulation it was verified a prevalent impeller effect at low speeds, propelling a large volume of fluid against the walls of the vessel, which without recirculation, results in low values of eG and kLa; however, by increasing air velocity, the impeller effect is smaller with the air flow being greater, in the region of the riser, causing fluid recirculation, which explains the increase in eG and kLa.
Abstract: Electric machines are driven nowadays by static system popularly known as soft starter. This paper describes a thyristor based static frequency converter (SFC) to run a large synchronous machine installed at a short circuit test laboratory. Normally a synchronous machine requires prime mover or some other driving mechanism to run. This machine doesn’t need a prime mover as it operates in dual mode. In the beginning SFC starts this machine as a motor to achieve the full speed. Thereafter whenever required it can be converted to generator mode. This paper begins with the various starting methodology of synchronous machine. Detailed of SFC with different operational modes have been analyzed. Shaft voltage is a very common phenomenon for the machines with static drives. Various causes of shaft voltages in perspective with this machine are the main attraction of this paper.
Abstract: This study was conducted to generate empirical evidence on validity and reliability of the item of Competency Assessment Implementation (CAI) Instrument using Rasch Model for polythomous data aided by Winstep software version 3.68. The construct validity was examined by analyzing the point-measure correlation index (PTMEA), infit and outfit MNSQ values; meanwhile the reliability was examined by analyzing item reliability index. A survey technique was used as the major method with the CAI instrument on 156 teachers from vocational schools. The results have shown that the reliability of CAI Instrument items were between 0.80 and 0.98. PTMEA Correlation is in positive values, in which the item is able to distinguish between the ability of the respondent. Statistical data obtained show that out of 154 items, 12 items from the instrument suggested to be omitted. This study is hoped could bring a new direction to the process of data analysis in educational research.
Abstract: We propose the numerical method defined by
xn+1 = xn − λ[f(xn − μh(xn))/]f'(xn) , n ∈ N,
and determine the control parameter λ and μ to converge cubically. In addition, we derive the asymptotic error constant. Applying this proposed scheme to various test functions, numerical results show a good agreement with the theory analyzed in this paper and are proven using Mathematica with its high-precision computability.
Abstract: Gastrointestinal parasitic infections are common health problems in sub-Saharan Africa. A cross- sectional study was carried out to determine the prevalence of gastrointestinal parasites among workers in major abattoirs in Port Harcourt, Nigeria. These abattoirs are located in Trans-Amadi, Rumuodumaya, Mile III and Easter-by-Pass. Formol-ether concentration technique was used to isolate the ova and cysts from faecal samples. Out of 201 workers (herdsmen, butchers, and cleaners) investigated for the presence of these parasites, 89 (44.2%) were infected with one or more parasites. The prevalence of the parasites among herdsmen and cleaners was significantly (P0.05) difference in the prevalence of gastrointestinal parasites in relation to age. Parasites identified included Ascaris lumbricoide (33.3%), tapeworm (4.97%), Entamoeba histolytica (5.47%), hookworms (13.9%), Trichuris trichiura (9.95%), Gardia lamblia (3.48%), and Schistosoma mansoni (1.9%). The frequency of A. lumbricoide was significantly (P
Abstract: In the present paper, an experimental investigation was conducted to study the thermodynamic of uranium extraction from Tunisian wet phosphoric acid using the synergistic solvent mixture of di-2-ethylhexyl phosphoric acid (DEHPA) and trioctyl phosphine oxid (TOPO) diluted in kerosene. The effect of different factors affecting the extraction process (temperature, TOPO and DEHPA concentrations) has been investigated. The obtained data of temperature effect on the extraction showed that the enthalpy change is -35.8 kJ.mol-1. The slope analysis method was used for determining the stoichiometry of the extracted species.
Abstract: Dielectric materials play an important role in broad applications, such as electrical and electromagnetic applications. This research studied the prediction of effective permeability of composite and nanocomposite dielectric materials based on theoretical analysis to specify the effects of embedded magnetic inclusions in enhancing magnetic properties of dielectrics. Effective permeability of Plastics and Glass nanodielectrics have been predicted with adding various types and percentages of magnetic nano-particles (Fe, Ni-Cu, Ni-Fe, MgZn_Ferrite, NiZn_Ferrite) for formulating new nanodielectric magnetic industrial materials. Soft nanoparticles powders that have been used in new nanodielectrics often possess the structure of a particle size in the range of micrometer- to nano-sized grains and magnetic isotropy, e.g., a random distribution of magnetic easy axes of the nanograins. It has been succeeded for enhancing characteristics of new nanodielectric magnetic industrial materials. The results have shown a significant effect of inclusions distribution on the effective permeability of nanodielectric magnetic composites, and so, explained the effect of magnetic inclusions types and their concentration on the effective permeability of nanodielectric magnetic materials.
Abstract: Recently, increased attention has been devoted to the voltage instability phenomenon in power systems. Many techniques have been proposed in the literature for evaluating and predicting voltage stability using steady state analysis methods. In this paper P-V and Q-V curves have been generated for a 57 bus Patiala Rajpura circle of India. The power-flow program is developed in MATLAB using Newton Raphson method. Using Q-V curves the weakest bus of the power system and the maximum reactive power change permissible on that bus is calculated. STATCOMs are placed on the weakest bus to improve the voltage and hence voltage stability and also the power transmission capability of the line.
Abstract: The dynamic economic dispatch (DED) problem is one of the complex constrained optimization problems that have nonlinear, con-convex and non-smooth objective functions. The purpose of the DED is to determine the optimal economic operation of the committed units while meeting the load demand. Associated to this constrained problem there exist highly nonlinear and non-convex practical constraints to be satisfied. Therefore, classical and derivative-based methods are likely not to converge to an optimal or near optimal solution to such a dynamic and large-scale problem. In this paper, an Artificial Immune System technique (AIS) is implemented and applied to solve the DED problem considering the transmission power losses and the valve-point effects in addition to the other operational constraints. To demonstrate the effectiveness of the proposed technique, two case studies are considered. The results obtained using the AIS are compared to those obtained by other methods reported in the literature and found better.
Abstract: Thyristor based firing angle controlled voltage regulators are extensively used for speed control of single phase induction motors. This leads to power saving but the applied voltage and current waveforms become non-sinusoidal. These non-sinusoidal waveforms increase voltage and thermal stresses which result into accelerated insulation aging, thus reducing the motor life. Life models that allow predicting the capability of insulation under such multi-stress situations tend to be very complex and somewhat impractical. This paper presents the fuzzy logic application to investigate the synergic effect of voltage and thermal stresses on intrinsic aging of induction motor insulation. A fuzzy expert system is developed to estimate the life of induction motor insulation under multiple stresses. Three insulation degradation parameters, viz. peak modification factor, wave shape modification factor and thermal loss are experimentally obtained for different firing angles. Fuzzy expert system consists of fuzzyfication of the insulation degradation parameters, algorithms based on inverse power law to estimate the life and defuzzyficaton process to output the life. An electro-thermal life model is developed from the results of fuzzy expert system. This fuzzy logic based electro-thermal life model can be used for life estimation of induction motors operated with non-sinusoidal voltage and current waveforms.