Abstract: Downward turbulent bubbly flows in pipes were
modeled using computational fluid dynamics tools. The
Hydrodynamics, phase distribution and turbulent structure of twophase
air-water flow in a 57.15 mm diameter and 3.06 m length
vertical pipe was modeled by using the 3-D Eulerian-Eulerian
multiphase flow approach. Void fraction, liquid velocity and
turbulent fluctuations profiles were calculated and compared against
experimental data. CFD results are in good agreement with
experimental data.
Abstract: Tuberculosis (TB) is a bacterial infectious disease caused by the obligate human pathogen, Mycobacterium tuberculosis. Multidrug-resistant tuberculosis (MDR-TB) is a global reality that threatens tuberculosis control. Resistance to antibiotic Rifampicin, occurs in 95% of cases through nucleotide substitutions in an 81-bp core region of the rpoB i.e; beta subunit of DNA dependant RNA polymerase. In this paper, we studied the Rifampicin-rpoB receptor interactions In silico. First, homology modeling was performed to obtain the three dimensional structure of Mycobacterium rpoB. Sixty analogs of Rifampicin were prepared using Marvin sketch software. Both original Rifampicin and the analogs were docked with rpoB and energy values were obtained. Out of sixty analogs, 43 analogs had lesser energy values than conventional Rifampicin and hence are predicted to have greater binding affinity to rpoB. Thus, this study offers a route for the development of Rifampicin analogs against multi drug resistant Mycobacterium rpoB.
Abstract: Surface currents play a major role in the distribution
of contaminants, the connectivity of marine populations, and can
influence the vertical and horizontal distribution of nutrients within
the water column. This paper aims to determine the effects of sea
breeze-wind patterns on the climatology of the surface currents on the
continental shelf surrounding Rottnest Island, WA Australia. The
alternating wind patterns allow for full cyclic rotations of wind
direction, permitting the interpretation of the effect of the wind on the
surface currents. It was found that the surface currents only clearly
follow the northbound Capes Current in times when the Fremantle
Doctor sets in. Surface currents react within an hour to a change of
direction of the wind, allowing southerly currents to dominate during
strong northerly sea breezes, often followed by mixed currents
dominated by eddies in the inter-lying times.
Abstract: To improve the characterization of blood flows, we propose a method which makes it possible to use the spectral analysis
of the Doppler signals. Our calculation induces a reasonable approximation, the error made on estimated speed reflects the fact
that speed depends on the flow conditions as well as on measurement parameters like the bore and the volume flow rate. The estimate of the Doppler signal frequency enables us to determine the maximum Doppler frequencie Fd max as well as the maximum flow speed. The
results show that the difference between the estimated frequencies
( Fde ) and the Doppler frequencies ( Fd ) is small, this variation tends to zero for important θ angles and it is proportional to the diameter D. The description of the speed of friction and the
coefficient of friction justify the error rate obtained.
Abstract: Virtualization-based server consolidation has been
proven to be an ideal technique to solve the server sprawl problem by
consolidating multiple virtualized servers onto a few physical servers
leading to improved resource utilization and return on investment. In
this paper, we solve this problem by using existing servers, which are
heterogeneous and diversely preferred by IT managers. Five practical
consolidation rules are introduced, and a decision model is proposed to
optimally allocate source services to physical target servers while
maximizing the average resource utilization and preference value. Our
model can be regarded as a multi-objective multi-dimension
bin-packing (MOMDBP) problem with constraints, which is strongly
NP-hard. An improved grouping generic algorithm (GGA) is
introduced for the problem. Extensive simulations were performed and
the results are given.
Abstract: For identifying the discriminative sequence features between exons and introns, a new paradigm, rescaled-range frameshift analysis (RRFA), was proposed. By RRFA, two new
sequence features, the frameshift sensitivity (FS) and the accumulative
penta-mer complexity (APC), were discovered which
were further integrated into a new feature of larger scale, the persistency in anti-mutation (PAM). The feature-validation experiments
were performed on six model organisms to test the power
of discrimination. All the experimental results highly support that FS, APC and PAM were all distinguishing features between exons
and introns. These identified new sequence features provide new insights into the sequence composition of genes and they have
great potentials of forming a new basis for recognizing the exonintron boundaries in gene sequences.
Abstract: Since the last two decades, container transportation
system has been faced under increasing development. This fact
shows the importance of container transportation system as a key role
of container terminals to link between sea and land. Therefore, there
is a continuous need for the optimal use of equipment and facilities in
the ports. Regarding the complex structure of container ports, this
paper presents a simulation model that compares tow storage
strategies for storing containers in the yard. For this purpose, we
considered loading and unloading norm as an important criterion to
evaluate the performance of Shahid Rajaee container port. By
analysing the results of the model, it will be shown that using
marshalling yard policy instead of current storage system has a
significant effect on the performance level of the port and can
increase the loading and unloading norm up to 14%.
Abstract: Numerous facts evidence the increasing religiosity of
the population and the intensification of religious movements in
various countries in the last decade of the 20th century. The number
of international religious institutions and foundations; religious
movements; parties and sects operating worldwide is increasing as
well. Some ethnic and inter-state conflicts are obviously of a
religious origin. All of this make a number of analysts to conclude
that the religious factor is becoming an important part of international
life, including the formation and activities of terrorist organizations.
Most of all is said and written about Islam, the second, after
Christianity, world religions professed according to various estimates
by 1.5 bln. individuals in 127 countries.
Abstract: Nowadays, fluidized bed plays an important part in industry. The design of this kind of reactor requires knowing the interfacial area between two phases and this interfacial area leads to calculate the solid holdup in the bed. Consequently achieving interfacial area between gas and solid in the bed experimentally is so significant. On interfacial area measurement in fluidized bed with gas has been worked, but light transmission technique has been used less. Therefore, in the current research the possibility of using of this technique and its accuracy are investigated. Measuring, a fluidized bed was designed and the problems were averted as far as possible. By using fine solid with equal shape and diameter and installing an optical system, the absorption of light during the time of fluidization has been measured. Results indicate that this method that its validity has been proved in the gas-liquid system, by different reasons have less application in gas-solid system. One important reason could be non-uniformity in such systems.
Abstract: The renewable energy has been attracting attention as
a new alternative energy due to the problem of environmental
pollution and resource depletion. In particular, daylighting and PV
system are regarded as the solutions. In this paper, the hybrid
dimming control system supplied by solar cell and daylighting
system was designed. Daylighting system is main source and PV
system is spare source. PV system operates the LED lamp which
supports daylighting system because daylighting system is unstable
due to the variation of irradiance. In addition, PV system has a role
charging batteries. Battery charging has a benefit that PV system
operate LED lamp in the bad weather. However, LED lamp always
can`t turn on that-s why dimming control system was designed. In
particular, the solar charging robot was designed to check the
interior irradiance intensity. These systems and the application of
the solar charging robot are expected to contribute developing
alternative energy in the near future.
Abstract: Traditional optical networks are gradually evolving towards intelligent optical networks due to the need for faster bandwidth provisioning, protection and restoration of the network that can be accomplished with devices like optical switch, add drop multiplexer and cross connects. Since dense wavelength multiplexing forms the physical layer for intelligent optical networking, the roll of high speed all optical switch is important. This paper analyzes such an ultra-high speed polymer electro-optic switch. The performances of the 2x2 optical waveguide switch with rectangular, triangular and trapezoidal grating profiles on various device parameters are analyzed. The simulation result shows that trapezoidal grating is the optimized structure which has the coupling length of 81μm and switching voltage of 11V for the operating wavelength of 1550nm. The switching time for this proposed switch is 0.47 picosecond. This makes the proposed switch to be an important element in the intelligent optical network.
Abstract: Extensive rainfall disaggregation approaches have been developed and applied in climate change impact studies such as flood risk assessment and urban storm water management.In this study, five rainfall models that were capable ofdisaggregating daily rainfall data into hourly one were investigated for the rainfall record in theChangi Airport, Singapore. The objectives of this study were (i) to study the temporal characteristics of hourly rainfall in Singapore, and (ii) to evaluate the performance of variousdisaggregation models. The used models included: (i) Rectangular pulse Poisson model (RPPM), (ii) Bartlett-Lewis Rectangular pulse model (BLRPM), (iii) Bartlett-Lewis model with 2 cell types (BL2C), (iv) Bartlett-Lewis Rectangular with cell depth distribution dependent on duration (BLRD), and (v) Neyman-Scott Rectangular pulse model (NSRPM). All of these models werefitted using hourly rainfall data ranging from 1980 to 2005 (which was obtained from Changimeteorological station).The study results indicated that the weight scheme of inversely proportional variance could deliver more accurateoutputs for fitting rainfall patterns in tropical areas, and BLRPM performedrelatively better than other disaggregation models.
Abstract: The Minimum Vertex Cover (MVC) problem is a classic
graph optimization NP - complete problem. In this paper a competent
algorithm, called Vertex Support Algorithm (VSA), is designed to
find the smallest vertex cover of a graph. The VSA is tested on a
large number of random graphs and DIMACS benchmark graphs.
Comparative study of this algorithm with the other existing methods
has been carried out. Extensive simulation results show that the VSA
can yield better solutions than other existing algorithms found in the
literature for solving the minimum vertex cover problem.
Abstract: Linear stability analysis of wake-shear layers in twophase
shallow flows is performed in the present paper. Twodimensional
shallow water equations are used in the analysis. It is
assumed that the fluid contains uniformly distributed solid particles.
No dynamic interaction between the carrier fluid and particles is
expected in the initial moment. The stability calculations are
performed for different values of the particle loading parameter and
two other parameters which characterize the velocity ratio and the
velocity deficit. The results show that the particle loading parameter
has a stabilizing effect on the flow while the increase in the velocity
ratio or in the velocity deficit destabilizes the flow.
Abstract: Retinoic acid is like a steroid hormone that plays a
role in embryo formation, proliferation of spermatogonia cells,
ephitelial cells differentiation and organogenesis. Retinoic acid can
influences seminiferous tubule formation during embryonic testis
development and also play a role in the regulation of ovarian function
and female reproductive tract by suppressing the hormones FSH
receptor expression. The excessive use of retinoic acid caused
abnormalities in the fetus. The result showed that there is the
influence of retinoic acid on the developmet of mice fetal testes, for
examples disruption of the formation of seminiferous tubules and
tubules seemed to be hollow, spermatogonia cells are relatively few
in number and caused Leydig cells count relatively more. While in
the female fetus does not caused the formation of primordial follicles
and disrupted the development of germinal ephitelial cells of fetal
ovaries of female mice (mus musculus) Swiss Webster.
Abstract: The spectral action balance equation is an equation that
used to simulate short-crested wind-generated waves in shallow water
areas such as coastal regions and inland waters. This equation consists
of two spatial dimensions, wave direction, and wave frequency which
can be solved by finite difference method. When this equation with
dominating convection term are discretized using central differences,
stability problems occur when the grid spacing is chosen too coarse.
In this paper, we introduce the splitting upwind schemes for avoiding
stability problems and prove that it is consistent to the upwind scheme
with same accuracy. The splitting upwind schemes was adopted
to split the wave spectral action balance equation into four onedimensional
problems, which for each small problem obtains the
independently tridiagonal linear systems. For each smaller system
can be solved by direct or iterative methods at the same time which
is very fast when performed by a multi-processor computer.
Abstract: In the last decade, energy based control theory has undergone a significant breakthrough in dealing with underactated mechanical systems with two successful and similar tools, controlled Lagrangians and controlled Hamiltanians (IDA-PBC). However, because of the complexity of these tools, successful case studies are lacking, in particular, MIMO cases. The seminal theoretical paper of controlled Lagrangians proposed by Bloch and his colleagues presented a benchmark example–a 4 d.o.f underactuated pendulum on a cart but a detailed and completed design is neglected. To compensate this ignorance, the note revisit their design idea by addressing explicit control functions for a similar device motivated by a vector thrust body hovering in the air. To the best of our knowledge, this system is the first MIMO, underactuated example that is stabilized by using energy based tools at the courtesy of the original design idea. Some observations are given based on computer simulation.
Abstract: Software-as-a-Service (SaaS) is a form of cloud
computing that relieves the user of the burden of hardware and
software installation and management. SaaS can be used at the course
level to enhance curricula and student experience. When cloud
computing and SaaS are included in educational literature, the focus
is typically on implementing administrative functions. Yet, SaaS can
make more immediate and substantial contributions to the technical
course content in educational offerings. This paper explores cloud
computing and SaaS, provides examples, reports on experiences
using SaaS to offer specialized software in courses, and analyzes the
advantages and disadvantages of using SaaS at the course level. The
paper contributes to the literature in higher education by analyzing
the major technical concepts, potential, and constraints for using
SaaS to deliver specialized software at the course level. Further it
may enable more educators and students to benefit from this
emerging technology.
Abstract: Microarrays have become the effective, broadly used tools in biological and medical research to address a wide range of problems, including classification of disease subtypes and tumors. Many statistical methods are available for analyzing and systematizing these complex data into meaningful information, and one of the main goals in analyzing gene expression data is the detection of samples or genes with similar expression patterns. In this paper, we express and compare the performance of several clustering methods based on data preprocessing including strategies of normalization or noise clearness. We also evaluate each of these clustering methods with validation measures for both simulated data and real gene expression data. Consequently, clustering methods which are common used in microarray data analysis are affected by normalization and degree of noise and clearness for datasets.
Abstract: In this paper, a two-dimensional (2D) numerical
model for the tidal currents simulation in Persian Gulf is presented.
The model is based on the depth averaged equations of shallow water
which consider hydrostatic pressure distribution. The continuity
equation and two momentum equations including the effects of bed
friction, the Coriolis effects and wind stress have been solved. To
integrate the 2D equations, the Alternative Direction Implicit (ADI)
technique has been used. The base of equations discritization was
finite volume method applied on rectangular mesh. To evaluate the
model validation, a dam break case study including analytical
solution is selected and the comparison is done. After that, the
capability of the model in simulation of tidal current in a real field is
represented by modeling the current behavior in Persian Gulf. The
tidal fluctuations in Hormuz Strait have caused the tidal currents in
the area of study. Therefore, the water surface oscillations data at
Hengam Island on Hormoz Strait are used as the model input data.
The check point of the model is measured water surface elevations at
Assaluye port. The comparison between the results and the
acceptable agreement of them showed the model ability for modeling
marine hydrodynamic.