Abstract: Studying stress and strain trends in the femur and
recognizing femur failure mechanism is very important for
preventing hip fracture in the elderly. The aim of this study was to
identify high stress and strain regions in the femur during normal
walking and falling to find the mechanical behavior and failure
mechanism of the femur. We developed a finite element model of the
femur from the subject’s quantitative computed tomography (QCT)
image and used it to identify potentially high stress and strain regions
during the single-leg stance and the sideways fall. It was found that
fracture may initiate from the superior region of femoral neck and
propagate to the inferior region during a high impact force such as
sideways fall. The results of this study showed that the femur bone is
more sensitive to strain than stress which indicates the effect of
strain, in addition to effect of stress, should be considered for failure
analysis.
Abstract: Cell processing techniques for gene and cell therapies use several separate procedures for gene transfer and cell separation or elimination, because no current technology can offer simultaneous multi-functional processing of specific cell sub-sets in heterogeneous cell systems. Using our novel on-demand nonstationary intracellular events instead of permanent materials, plasmonic nanobubbles, generated with a short laser pulse only in target cells, we achieved simultaneous multifunctional cell-specific processing with the rate up to 50 million cells per minute.
Abstract: Extensive rainfall disaggregation approaches have been developed and applied in climate change impact studies such as flood risk assessment and urban storm water management.In this study, five rainfall models that were capable ofdisaggregating daily rainfall data into hourly one were investigated for the rainfall record in theChangi Airport, Singapore. The objectives of this study were (i) to study the temporal characteristics of hourly rainfall in Singapore, and (ii) to evaluate the performance of variousdisaggregation models. The used models included: (i) Rectangular pulse Poisson model (RPPM), (ii) Bartlett-Lewis Rectangular pulse model (BLRPM), (iii) Bartlett-Lewis model with 2 cell types (BL2C), (iv) Bartlett-Lewis Rectangular with cell depth distribution dependent on duration (BLRD), and (v) Neyman-Scott Rectangular pulse model (NSRPM). All of these models werefitted using hourly rainfall data ranging from 1980 to 2005 (which was obtained from Changimeteorological station).The study results indicated that the weight scheme of inversely proportional variance could deliver more accurateoutputs for fitting rainfall patterns in tropical areas, and BLRPM performedrelatively better than other disaggregation models.