Abstract: Leukaemia is a blood cancer disease that contributes
to the increment of mortality rate in Malaysia each year. There are
two main categories for leukaemia, which are acute and chronic
leukaemia. The production and development of acute leukaemia cells
occurs rapidly and uncontrollable. Therefore, if the identification of
acute leukaemia cells could be done fast and effectively, proper
treatment and medicine could be delivered. Due to the requirement of
prompt and accurate diagnosis of leukaemia, the current study has
proposed unsupervised pixel segmentation based on clustering
algorithm in order to obtain a fully segmented abnormal white blood
cell (blast) in acute leukaemia image. In order to obtain the
segmented blast, the current study proposed three clustering
algorithms which are k-means, fuzzy c-means and moving k-means
algorithms have been applied on the saturation component image.
Then, median filter and seeded region growing area extraction
algorithms have been applied, to smooth the region of segmented
blast and to remove the large unwanted regions from the image,
respectively. Comparisons among the three clustering algorithms are
made in order to measure the performance of each clustering
algorithm on segmenting the blast area. Based on the good sensitivity
value that has been obtained, the results indicate that moving kmeans
clustering algorithm has successfully produced the fully
segmented blast region in acute leukaemia image. Hence, indicating
that the resultant images could be helpful to haematologists for
further analysis of acute leukaemia.
Abstract: Risperidone (RISP) is an antipsychotic agent and has
low water solubility and nontargeted delivery results in numerous
side effects. Hence, an attempt was made to develop SLNs hydrogel
for intranasal delivery of RISP to achieve maximum bioavailability
and reduction of side effects. RISP loaded SLNs composed of 1.65%
(w/v) lipid mass were produced by high shear homogenization (HSH)
coupled ultrasound (US) method using glycerylmonostearate (GMS)
or Imwitor 900K (solid lipid). The particles were loaded with 0.2%
(w/v) of the RISP & surface-tailored with a 2.02% (w/v) non-ionic
surfactant Tween® 80. Optimization was done using 32 factorial
design using Design Expert® software. The prepared SLNs
dispersion incorporated into Polycarbophil AA1 hydrogel (0.5%
w/v). The final gel formulation was evaluated for entrapment
efficiency, particle size, rheological properties, X ray diffraction, in
vitro diffusion, ex vivo permeation using sheep nasal mucosa and
histopathological studies for nasocilliary toxicity. The entrapment
efficiency of optimized SLNs was found to be 76 ± 2%,
polydispersity index
Abstract: Welfare may be considered to be a subjective
experience; it has a biological function that is related to the fitness
and survival of the animal accordingly, researches have suggested
that welfare is compromised when the animal's evolutionary fitness is
reduced. This study was carried out to explain the effect of some
managerial stressors as handling and restraint on behavioral patterns
and biochemical parameters of rats. A total of 24 (12 males & 12
females) Sprague-Dawley rats (12 months & 150-180g) were allotted
into 3 groups, handled group (4 male & 4 female), restrained group (4
male & 4 female) and control group (4 males & 4 females).
The obtained results revealed that time spent feeding, drinking,
movement and cage exploration frequencies increased significantly in
handled rats than other groups, while lying time and licking increased
significantly in restrained rats than handled and controls. Moreover,
social behavior decreased in both stressed groups than control.
Triglycerides were significantly increased in handled rats than
other groups, while total lipid, total protein and globulin significantly
increased in both treated groups than control. Corticosterone
increased in restrained and handled rats than control ones. Moreover,
there was an increment in packed cell volume significantly in
restrained rats than others. These deducted that if we want to study
the effect of stress on animal welfare it is necessary to study the
effect of such stressors on animal’s behavior and physiological
responses.
Abstract: Wireless mesh networking is rapidly gaining in
popularity with a variety of users: from municipalities to enterprises,
from telecom service providers to public safety and military
organizations. This increasing popularity is based on two basic facts:
ease of deployment and increase in network capacity expressed in
bandwidth per footage; WMNs do not rely on any fixed
infrastructure. Many efforts have been used to maximizing
throughput of the network in a multi-channel multi-radio wireless
mesh network. Current approaches are purely based on either static or
dynamic channel allocation approaches. In this paper, we use a
hybrid multichannel multi radio wireless mesh networking
architecture, where static and dynamic interfaces are built in the
nodes. Dynamic Adaptive Channel Allocation protocol (DACA), it
considers optimization for both throughput and delay in the channel
allocation. The assignment of the channel has been allocated to be codependent
with the routing problem in the wireless mesh network and
that should be based on passage flow on every link. Temporal and
spatial relationship rises to re compute the channel assignment every
time when the pattern changes in mesh network, channel assignment
algorithms assign channels in network. In this paper a computing
path which captures the available path bandwidth is the proposed
information and the proficient routing protocol based on the new path
which provides both static and dynamic links. The consistency
property guarantees that each node makes an appropriate packet
forwarding decision and balancing the control usage of the network,
so that a data packet will traverse through the right path.
Abstract: A feeding experiment was conducted to determine the
optimum dietary protein and lipid levels for juvenile fancy carp. Eight
experimental diets were formulated to contain four protein levels (200,
300, 400 and 500 g kg-1) with two lipid levels (70 and 140 g kg-1).
Triplicate groups of fish (initial weight, 12.1±0.2 g fish-1) were
hand-fed the diets to apparent satiation for 8 weeks. Fish growth
performance, feed utilization and feed intake were significantly
(P0.05). Weight gain and feed efficiency ratio tended to
increase as dietary protein level increased up to 400 and 500 g kg-1,
respectively. Daily feed intake of fish decreased with increasing
dietary protein level and that of fish fed diet contained 500 g kg-1
protein was significantly lower than other fish groups. The protein
efficiency ratio of fish fed 400 and 500 g kg-1 protein was lower than
that of fish fed 200 and 300 g kg-1 protein. Moisture, crude protein and
crude lipid contents of muscle and liver were significantly affected by
dietary protein, but not by dietary lipid level (P>0.05). The increase in
dietary lipid level resulted in an increase in linoleic acid in liver and
muscle paralleled with a decrease in n-3 highly unsaturated fatty acids
content in muscle of fish. In considering these results, it was concluded
that the diet containing 400 g kg-1 protein with 70 g kg-1 lipid level is
optimal for growth and efficient feed utilization of juvenile fancy carp.
Abstract: The thermal conductivity of a fluid can be
significantly enhanced by dispersing nano-sized particles in it, and
the resultant fluid is termed as "nanofluid". A theoretical model for
estimating the thermal conductivity of a nanofluid has been proposed
here. It is based on the mechanism that evenly dispersed
nanoparticles within a nanofluid undergo Brownian motion in course
of which the nanoparticles repeatedly collide with the heat source.
During each collision a rapid heat transfer occurs owing to the solidsolid
contact. Molecular dynamics (MD) simulation of the collision
of nanoparticles with the heat source has shown that there is a pulselike
pick up of heat by the nanoparticles within 20-100 ps, the extent
of which depends not only on thermal conductivity of the
nanoparticles, but also on the elastic and other physical properties of
the nanoparticle. After the collision the nanoparticles undergo
Brownian motion in the base fluid and release the excess heat to the
surrounding base fluid within 2-10 ms. The Brownian motion and
associated temperature variation of the nanoparticles have been
modeled by stochastic analysis. Repeated occurrence of these events
by the suspended nanoparticles significantly contributes to the
characteristic thermal conductivity of the nanofluids, which has been
estimated by the present model for a ethylene glycol based nanofluid
containing Cu-nanoparticles of size ranging from 8 to 20 nm, with
Gaussian size distribution. The prediction of the present model has
shown a reasonable agreement with the experimental data available
in literature.
Abstract: e-Service has moved from the usual manual and
traditional way of rendering services to electronic service provision
for the public and there are several reasons for implementing these
services, Airline ticketing have gone from its manual traditional way
to an intelligent web-driven service of purchasing. Many companies
have seen their profits doubled through the use of online services in
their operation and a typical example is Hewlett Packard (HP) which
is rapidly transforming their after sales business into a profit
generating e-service business unit.
This paper will examine the various challenges confronting e-
Service adoption and implementation in Nigeria and also analyse
lessons learnt from e-Service adoption and implementation in Asia to
see how it could be useful in Nigeria which is a lower middle income
country. From the analysis of the online survey data, it has been
identified that the public in Nigeria are much aware of e-Services but
successful adoption and implementation have been the problems
faced.
Abstract: Liposome plays an important role in medical and
pharmaceutical science as e.g. nano scale drug carriers. Liposomes
are vesicles of varying size consisting of a spherical lipid bilayer and
an aqueous inner compartment. Magnet-driven liposome used for the
targeted delivery of drugs to organs and tissues. These liposome
preparations contain encapsulated drug components and finely
dispersed magnetic particles.
Liposomes are vesicles of varying size consisting of a spherical
lipid bilayer and an aqueous inner compartment that are generated in
vitro. These are useful in terms of biocompatibility, biodegradability,
and low toxicity, and can control biodistribution by changing the size,
lipid composition, and physical characteristics. Furthermore,
liposomes can entrap both hydrophobic and hydrophilic drugs and are
able to continuously release the entrapped substrate, thus being useful
drug carriers. Magnetic liposomes (MLs) are phospholipid vesicles
that encapsulate magneticor paramagnetic nanoparticles. They are
applied as contrast agents for magnetic resonance imaging (MRI).
The biological synthesis of nanoparticles using plant extracts plays
an important role in the field of nanotechnology. Green-synthesized
magnetite nanoparticles-protein hybrid has been produced by treating
Iron (III) / Iron (II) chloride with the leaf extract of Datura inoxia.
The phytochemicals present in the leaf extracts act as a reducing as
well stabilizing agents preventing agglomeration, which include
flavonoids, phenolic compounds, cardiac glycosides, proteins and
sugars.
The magnetite nanoparticles-protein hybrid has been trapped
inside the aqueous core of the liposome prepared by reversed phase
evaporation (REV) method using oleic and linoleic acid which has
been shown to be driven under magnetic field confirming the
formation magnetic liposome (ML). Chemical characterization of
stealth magnetic liposome has been performed by breaking the
liposome and release of magnetic nanoparticles. The presence iron
has been confirmed by colour complex formation with KSCN and
UV-Vis study using spectrophotometer Cary 60, Agilent.
This magnet driven liposome using nanoparticles-protein hybrid
can be a smart vesicles for the targeted drug delivery.
Abstract: This paper provides a comparative study on the
performances of standard PID and adaptive PID controllers tested on
travel angle of a 3-Degree-of-Freedom (3-DOF) Quanser bench-top
helicopter. Quanser, a well-known manufacturer of educational
bench-top helicopter has developed Proportional Integration
Derivative (PID) controller with Linear Quadratic Regulator (LQR)
for all travel, pitch and yaw angle of the bench-top helicopter. The
performance of the PID controller is relatively good; however, its
performance could also be improved if the controller is combined
with adaptive element. The objective of this research is to design
adaptive PID controller and then compare the performances of the
adaptive PID with the standard PID. The controller design and test is
focused on travel angle control only. Adaptive method used in this
project is self-tuning controller, which controller’s parameters are
updated online. Two adaptive algorithms those are pole-placement
and deadbeat have been chosen as the method to achieve optimal
controller’s parameters. Performance comparisons have shown that
the adaptive (deadbeat) PID controller has produced more desirable
performance compared to standard PID and adaptive (poleplacement).
The adaptive (deadbeat) PID controller attained very fast
settling time (5 seconds) and very small percentage of overshoot (5%
to 7.5%) for 10° to 30° step change of travel angle.
Abstract: Cross flow water tube heat exchanger can be designed
and made operational using methods of model building and
simulation of the system. This paper projects the design and
development of a model of cross flow water tube heat-exchanger
system, simulation and validation of control analysis of different
tuning methods. Feedback and override control system is developed
using inputs acquired with the help of sensory system. A
mathematical model is formulated for analysis of system behaviour.
The temperature is regulated at the desired set point automatically.
Abstract: Logistics distributors face the issue of having to
provide increasing service levels while being forced to reduce costs at
the same time. Same-day delivery, quick order processing and rapidly
growing ranges of articles are only some of the prevailing challenges.
One key aspect of the performance of an intra-logistics system is how
often and in which amplitude congestions and dysfunctions affect the
processing operations. By gaining knowledge of the so called
‘performance availability’ of such a system during the planning stage,
oversizing and wasting can be reduced whereas planning
transparency is increased. State of the art for the determination of this
KPI is simulation studies. However, their structure and therefore their
results may vary unforeseeably. This article proposes a concept for
the establishment of ‘certified’ and hence reliable and comparable
simulation models.
Abstract: The classroom of the 21st century is an ever changing
forum for new and innovative thoughts and ideas. With increasing
technology and opportunity, students have rapid access to
information that only decades ago would have taken weeks to obtain.
Unfortunately, new techniques and technology are not the cure for
the fundamental problems that have plagued the classroom ever since
education was established. Class size has been an issue long debated
in academia. While it is difficult to pin point an exact number, it is
clear that in this case more does not mean better. By looking into the
success and pitfalls of classroom size the true advantages of smaller
classes will become clear. Previously, one class was comprised of 50
students. Being seventeen and eighteen- year- old students,
sometimes it was quite difficult for them to stay focused. To help
them understand and gain much knowledge, a researcher introduced
“The Theory of Multiple Intelligence” and this, in fact, enabled
students to learn according to their own learning preferences no
matter how they were being taught. In this lesson, the researcher
designed a cycle of learning activities involving all intelligences so
that everyone had equal opportunities to learn.
Abstract: The Smart Help for persons with disability (PWD) is a
part of the project SMARTDISABLE which aims to develop relevant
solution for PWD that target to provide an adequate workplace
environment for them. It would support PWD needs smartly through
smart help to allow them access to relevant information and
communicate with other effectively and flexibly, and smart editor
that assist them in their daily work. It will assist PWD in knowledge
processing and creation as well as being able to be productive at the
work place. The technical work of the project involves design of a
technological scenario for the Ambient Intelligence (AmI) - based
assistive technologies at the workplace consisting of an integrated
universal smart solution that suits many different impairment
conditions and will be designed to empower the Physically disabled
persons (PDP) with the capability to access and effectively utilize the
ICTs in order to execute knowledge rich working tasks with
minimum efforts and with sufficient comfort level. The proposed
technology solution for PWD will support voice recognition along
with normal keyboard and mouse to control the smart help and smart
editor with dynamic auto display interface that satisfies the
requirements for different PWD group. In addition, a smart help will
provide intelligent intervention based on the behavior of PWD to
guide them and warn them about possible misbehavior. PWD can
communicate with others using Voice over IP controlled by voice
recognition. Moreover, Auto Emergency Help Response would be
supported to assist PWD in case of emergency. This proposed
technology solution intended to make PWD very effective at the
work environment and flexible using voice to conduct their tasks at
the work environment. The proposed solution aims to provide
favorable outcomes that assist PWD at the work place, with the
opportunity to participate in PWD assistive technology innovation
market which is still small and rapidly growing as well as upgrading
their quality of life to become similar to the normal people at the
workplace. Finally, the proposed smart help solution is applicable in
all workplace setting, including offices, manufacturing, hospital, etc.
Abstract: This study presents a cost-effective approach for rapid
fabricating modeling platforms utilized in fused deposition modeling
system. A small-batch production of modeling platforms about 20
pieces can be obtained economically through silicone rubber mold
using vacuum casting without applying the plastic injection molding.
The air venting systems is crucial for fabricating modeling platform
using vacuum casting. Modeling platforms fabricated can be used for
building rapid prototyping model after sandblasting. This study offers
industrial value because it has both time-effectiveness and
cost-effectiveness.
Abstract: Regardless of the manufacturing process used,
subtractive or additive, material, purpose and application, produced
components are conventionally solid mass with more or less complex
shape depending on the production technology selected. Aspects
such as reducing the weight of components, associated with the low
volume of material required and the almost non-existent material
waste, speed and flexibility of production and, primarily, a high
mechanical strength combined with high structural performance, are
competitive advantages in any industrial sector, from automotive,
molds, aviation, aerospace, construction, pharmaceuticals, medicine
and more recently in human tissue engineering. Such features,
properties and functionalities are attained in metal components
produced using the additive technique of Rapid Prototyping from
metal powders commonly known as Selective Laser Melting (SLM),
with optimized internal topologies and varying densities. In order to
produce components with high strength and high structural and
functional performance, regardless of the type of application, three
different internal topologies were developed and analyzed using
numerical computational tools. The developed topologies were
numerically submitted to mechanical compression and four point
bending testing. Finite Element Analysis results demonstrate how
different internal topologies can contribute to improve mechanical
properties, even with a high degree of porosity relatively to fully
dense components. Results are very promising not only from the
point of view of mechanical resistance, but especially through the
achievement of considerable variation in density without loss of
structural and functional high performance.
Abstract: Underwater acoustic network is one of the rapidly
growing areas of research and finds different applications for
monitoring and collecting various data for environmental studies. The
communication among dynamic nodes and high error probability in
an acoustic medium forced to maximize energy consumption in
Underwater Sensor Networks (USN) than in traditional sensor
networks. Developing energy-efficient routing protocol is the
fundamental and a curb challenge because all the sensor nodes are
powered by batteries, and they cannot be easily replaced in UWSNs.
This paper surveys the various recent routing techniques that mainly
focus on energy efficiency.
Abstract: As enterprise computing becomes more and more
complex, the costs and technical challenges of IT system maintenance
and support are increasing rapidly. One popular approach to managing
IT system maintenance is to prepare and use a FAQ (Frequently Asked
Questions) system to manage and reuse systems knowledge. Such a
FAQ system can help reduce the resolution time for each service
incident ticket. However, there is a major problem where over time the
knowledge in such FAQs tends to become outdated. Much of the
knowledge captured in the FAQ requires periodic updates in response
to new insights or new trends in the problems addressed in order to
maintain its usefulness for problem resolution. These updates require a
systematic approach to define the exact portion of the FAQ and its
content. Therefore, we are working on a novel method to
hierarchically structure the FAQ and automate the updates of its
structure and content. We use structured information and the
unstructured text information with the timelines of the information in
the service incident tickets. We cluster the tickets by structured
category information, by keywords, and by keyword modifiers for the
unstructured text information. We also calculate an urgency score
based on trends, resolution times, and priorities. We carefully studied
the tickets of one of our projects over a 2.5-year time period. After the
first 6 months we started to create FAQs and confirmed they improved
the resolution times. We continued observing over the next 2 years to
assess the ongoing effectiveness of our method for the automatic FAQ
updates. We improved the ratio of tickets covered by the FAQ from
32.3% to 68.9% during this time. Also, the average time reduction of
ticket resolution was between 31.6% and 43.9%. Subjective analysis
showed more than 75% reported that the FAQ system was useful in
reducing ticket resolution times.
Abstract: To evaluate the factors which predetermine the
coronary artery disease in patients having positive Exercise Tolerance
Test (ETT) that is treadmill results and coronary artery findings. This
descriptive study was conducted at Department of Cardiology,
Ibrahim Cardiac Hospital & Research Institute, Dhaka, Bangladesh
from 1st January, 2014 to 31st August, 2014. All patients who had
done ETT (treadmill) for chest pain diagnosis were studied. One
hundred and four patients underwent coronary angiogram after
positive treadmill result. Patients were divided into two groups
depending upon the angiographic findings, i.e. true positive and false
positive. Positive treadmill test patients who have coronary artery
involvement these are called true positive and who have no
involvement they are called false positive group. Both groups were
compared with each other. Out of 104 patients, 81 (77.9%) patients
had true positive ETT and 23 (22.1%) patients had false positive
ETT. The mean age of patients in positive ETT was 53.46± 8.06
years and male mean age was 53.63±8.36 years and female was
52.87±7.0 years. Sixty nine (85.19%) male patients and twelve
(14.81%) female patients had true positive ETT, whereas 15
(65.21%) males and 8 (34.79%) females had false positive ETT, this
was statistically significant (p
Abstract: In regards to the energy sector in the modern period,
two points were raised. First is a vast and growing energy demand, and
second is an environmental impact associated with it. The enormous
consumption of fossil fuel to the mobile unit is leading to its rapid
depletion. Nuclear power is not the only problem. A modal shift that
utilizes personal transporters and independent power, in order to
realize a sustainable society, is very effective. The author proposes that
the world will continue to work on this. Energy of the future society,
innovation in battery technology and the use of natural energy is a big
key. And it is also necessary in order to save on energy consumption.
Abstract: In this research article a comprehensive investigation
has been carried out to determine the effect of thermal cycle on
temperature dependent process parameters developed during gas
tungsten arc (GTA) welding of high carbon (AISI 1090) steel butt
joints. An experiment based thermal analysis has been performed to
obtain the thermal history. We have focused on different
thermophysical properties such as thermal conductivity, heat transfer
coefficient and cooling rate. Angular torch model has been utilized to
find out the surface heat flux and its variation along the fusion zone as
well as along the longitudinal direction from fusion boundary. After
welding and formation of weld pool, heat transfer coefficient varies
rapidly in the vicinity of molten weld bead and heat affected zone. To
evaluate the heat transfer coefficient near the fusion line and near the
rear end of the plate (low temperature region), established correlation
has been implemented and has been compared with empirical
correlation which is noted as coupled convective and radiation heat
transfer coefficient. Change in thermal conductivity has been
visualized by analytical model of moving point heat source. Rate of
cooling has been estimated by using 2-dimensional mathematical
expression of cooling rate and it has shown good agreement with
experimental temperature cycle. Thermophysical properties have been
varied randomly within 0 -10s time span.