Abstract: Midpoint filter is quite effective in recovering the
images confounded by the short-tailed (uniform) noise. It, however,
performs poorly in the presence of additive long-tailed (impulse)
noise and it does not preserve the edge structures of the image
signals. Median smoother discards outliers (impulses) effectively, but
it fails to provide adequate smoothing for images corrupted with nonimpulse
noise. In this paper, two nonlinear techniques for image
filtering, namely, New Filter I and New Filter II are proposed based
on a nonlinear high-pass filter algorithm. New Filter I is constructed
using a midpoint filter, a highpass filter and a combiner. It suppresses
uniform noise quite well. New Filter II is configured using an alpha
trimmed midpoint filter, a median smoother of window size 3x3, the
high pass filter and the combiner. It is robust against impulse noise
and attenuates uniform noise satisfactorily. Both the filters are shown
to exhibit good response at the image boundaries (edges). The
proposed filters are evaluated for their performance on a test image
and the results obtained are included.
Abstract: Based on different experiences in the historic centers
of Spain, we propose an global strategy for the regeneration of the
pre-tertiary fabrics and its application to the specific case of San
Mateo neighborhood, in Jerez de la Frontera (Andalusia), through a
diagnosis that focus particularly on the punishments the last-decade
economic situation (building boom and crisis) and shows the tragic
transition from economic center to an imminent disappearance with
an image similar to the ruins of war, due to the loss of their
traditional roles. From it we will learn their historically-tested
mechanisms of environment adaptation, which distill the vernacular
architecture essence and that we will apply to our strategy of action
based on a dotacional-and-free-space rhizome which rediscovers its
hidden character. The architectural fact will be crystallized in one of
the example-pieces proposed: The Artistic Revitalization Center.
Abstract: Increasing user comfort and reducing operation costs
have always been primary objectives of lighting control strategies in a
building. This paper proposes an architecture of the lighting control
system for a daylit office. The system consists of the lighting
controller, A/D & D/A converter, dimmable LED lights, and the
lighting management software. Verification tests are conducted using
the proposed system specialized for the interior lighting of a open-plan
office. The results showed the proposed architecture of the lighting
system would improve the overall system reliability, lower the system
cost, and provide ease of installation and maintenance.
Abstract: Severe acute respiratory syndrome (SARS) is a respiratory disease in humans which is caused by the SARS coronavirus. The treatment of coronavirus-associated SARS has been evolving and so far there is no consensus on an optimal regimen. The mainstream therapeutic interventions for SARS involve broad-spectrum antibiotics and supportive care, as well as antiviral agents and immunomodulatory therapy. The Protein- Ligand interaction plays a significant role in structural based drug designing. In the present work we have taken the receptor Angiotensin converting enzyme 2 and identified the drugs that are commonly used against SARS. They are Lopinavir, Ritonavir, Ribavirin, and Oseltamivir. The receptor Angiotensin converting enzyme 2 (ACE-2) was docked with above said drugs and the energy value obtained are as follows, Lopinavir (-292.3), Ritonavir (-325.6), Oseltamivir (- 229.1), Ribavirin (-208.8). Depending on the least energy value we have chosen the best two drugs out of the four conventional drugs. We tried to improve the binding efficiency and steric compatibility of the two drugs namely Ritonavir and Lopinavir. Several modifications were made to the probable functional groups (phenylic, ketonic groups in case of Ritonavir and carboxylic groups in case of Lopinavir respectively) which were interacting with the receptor molecule. Analogs were prepared by Marvin Sketch software and were docked using HEX docking software. Lopinavir analog 8 and Ritonavir analog 11 were detected with significant energy values and are probable lead molecule. It infers that some of the modified drugs are better than the original drugs. Further work can be carried out to improve the steric compatibility of the drug based upon the work done above for a more energy efficient binding of the drugs to the receptor.
Abstract: This paper presents a cold flow simulation study of a small gas turbine combustor performed using laboratory scale test rig. The main objective of this investigation is to obtain physical insight of the main vortex, responsible for the efficient mixing of fuel and air. Such models are necessary for predictions and optimization of real gas turbine combustors. Air swirler can control the combustor performance by assisting in the fuel-air mixing process and by producing recirculation region which can act as flame holders and influences residence time. Thus, proper selection of a swirler is needed to enhance combustor performance and to reduce NOx emissions. Three different axial air swirlers were used based on their vane angles i.e., 30°, 45°, and 60°. Three-dimensional, viscous, turbulent, isothermal flow characteristics of the combustor model operating at room temperature were simulated via Reynolds- Averaged Navier-Stokes (RANS) code. The model geometry has been created using solid model, and the meshing has been done using GAMBIT preprocessing package. Finally, the solution and analysis were carried out in a FLUENT solver. This serves to demonstrate the capability of the code for design and analysis of real combustor. The effects of swirlers and mass flow rate were examined. Details of the complex flow structure such as vortices and recirculation zones were obtained by the simulation model. The computational model predicts a major recirculation zone in the central region immediately downstream of the fuel nozzle and a second recirculation zone in the upstream corner of the combustion chamber. It is also shown that swirler angles changes have significant effects on the combustor flowfield as well as pressure losses.
Abstract: Abovepresented work deals with the new scope of application of information and communication technologies for the improvement of the election process in the biased environment. We are introducing a new concept of construction of the information-communication system for the election participant. It consists of four main components: Software, Physical Infrastructure, Structured Information and the Trained Stuff. The Structured Information is the bases of the whole system and is the collection of all possible events (irregularities among them) at the polling stations, which are structured in special templates, forms and integrated in mobile devices.The software represents a package of analytic modules, which operates with the dynamic database. The application of modern communication technologies facilities the immediate exchange of information and of relevant documents between the polling stations and the Server of the participant. No less important is the training of the staff for the proper functioning of the system. The e-training system with various modules should be applied in this respect. The presented methodology is primarily focused on the election processes in the countries of emerging democracies.It can be regarded as the tool for the monitoring of elections process by the political organization(s) and as one of the instruments to foster the spread of democracy in these countries.
Abstract: The study of cytokine expression in mice under the
influence of inactivated poliovirus and Imovaks polio vaccine in
combination with derivatives of chitosan shows various kinds of
processes. There is a significant increase in IL-12 in the serum of
immunized animals, which should stimulate the production of IFN-γ
NK-cells and T-cells and polarize the immune response to Th1 type.
Thus, the derivatives of chitosan can promote cell component of the
immune response, providing a full antiviral immunity.
Abstract: One of the factors to maintain system survivability is
the adequate reactive power support to the system. Lack of reactive
power support may cause undesirable voltage decay leading to total
system instability. Thus, appropriate reactive power support scheme
should be arranged in order to maintain system stability. The strength
of a system capacity is normally denoted as system loadability. This
paper presents the enhancement of system loadability through
optimal reactive power planning technique using a newly developed
optimization technique, termed as Multiagent Immune Evolutionary
Programming (MAIEP). The concept of MAIEP is developed based
on the combination of Multiagent System (MAS), Artificial Immune
System (AIS) and Evolutionary Programming (EP). In realizing the
effectiveness of the proposed technique, validation is conducted on
the IEEE-26-Bus Reliability Test System. The results obtained from
pre-optimization and post-optimization process were compared
which eventually revealed the merit of MAIEP.
Abstract: Essential hypertension (HTN) usually clusters with other cardiovascular risk factors such as age, overweight, diabetes, insulin resistance and dyslipidemia. The target organ damage (TOD) such as left ventricular hypertrophy, microalbuminuria (MA), acute coronary syndrome (ACS), stroke and cognitive dysfunction takes place early in course of hypertension. Though the prevalence of hypertension is high in India, the relationship between microalbuminuria and target organ damage in hypertension is not well studied. This study aim at detecting MA in essential hypertension and its relation to severity of HTN, duration of HTN, body mass index (BMI), age and TOD such as HTN retinopathy and acute coronary syndrome The present study was done in 100 patients of essential hypertension non diabetics admitted to B.L.D.E.University-s Sri B.M.Patil Medical College, Bijapur, from October 2008 to April 2011. The patients underwent detailed history and clinical examination. Early morning 5 ml of urine sample was collected & MA was estimated by immunoturbidometry method. The relationship of MA with the duration & severity of HTN, BMI, age, sex and TOD's like hypertensive retinopathy, ACS was assessed by univariate analysis. The prevalence of MA in this study was found to be 63 %. In that 42% were male & 21% were female. In this study a significant association between MA and the duration of hypertension (p = 0.036) & (OR =0.438). Longer the duration of hypertension, more possibility of microalbumin in urine. Also there was a significant association between severity of hypertension and MA (p=0.045) and (OR=0.093). MA was positive in 50 (79.4%) patients out of 63, whose blood pressure was >160/100 mm Hg. In this study a significant association between MA and the grades of hypertensive retinopathy (p =0.011) and acute coronary syndrome (p = 0.041) (OR =2.805). Gender and BMI did not pose high risk for MA in this study.The prevalence of MA in essential hypertension is high in this part of the community and MA will increase the risk of developing target organ damage.Early screening of patients with essential hypertension for MA and aggressive management of positive cases might reduce the burden of chronic kidney diseases and cardiovascular diseases in the community.
Abstract: TiO2/Ag composite films were prepared by
incorporating Ag in the pores of mesoporous TiO2 films using a
photoreduction method. The Ag nanoparticle sizes were in a range of
3.66-38.56 nm. The TiO2/Ag composite films were characterized by
X-ray diffraction (XRD), scanning electron microscopy (SEM) and
transmission electron microscropy (TEM). The TiO2 films and
TiO2/Ag composite films were immersed in a 0.3 mM N719 dye
solution and characterized by UV-Vis spectrophotometer. The
TiO2/Ag/N719 composite film showed that an optimal size of Ag
nanoparticles was 19.12 nm and, hence, gave the maximum optical
absorption spectra. The improved absorption was due to surface
plasmon resonance induced by the Ag nanoparticles to enhance the
absorption coefficient of the dye.
Abstract: This paper analyzes the linkage between migration,
economic globalization and terrorism concerns. On a broad level, I
analyze Canadian economic and political considerations, searching
for causal relationships between political and economic actors on the
one hand, and Canadian immigration law on the other. Specifically,
the paper argues that there are contradictory impulses affecting state
sovereignty. These impulses are are currently being played out in the
field of Canadian immigration law through several proposed changes
to Canada-s Immigration and Refugee Protection Act (IRPA). These
changes reflect an ideological conception of sovereignty that is
intrinsically connected with decision-making capacity centered on an
individual. This conception of sovereign decision-making views
Parliamentary debate and bureaucratic inefficiencies as both equally
responsible for delaying essential decisions relating to the protection
of state sovereignty, economic benefits and immigration control This
paper discusses these concepts in relation to Canadian immigration
policy under Canadian governments over the past twenty five years.
Abstract: This work presents the Risk Threshold RED (RTRED)
congestion control strategy for TCP networks. In addition to the
maximum and minimum thresholds in existing RED-based strategies,
we add a third dropping level. This new dropping level is the risk
threshold which works with the actual and average queue sizes to
detect the immediate congestion in gateways. Congestion reaction
by RTRED is on time. The reaction to congestion is neither too
early, to avoid unfair packet losses, nor too late to avoid packet
dropping from time-outs. We compared our novel strategy with RED
and ARED strategies for TCP congestion handling using a NS-2
simulation script. We found that the RTRED strategy outperformed
RED and ARED.
Abstract: In this paper, the periodic surveillance scheme has
been proposed for any convex region using mobile wireless sensor
nodes. A sensor network typically consists of fixed number of
sensor nodes which report the measurements of sensed data such as
temperature, pressure, humidity, etc., of its immediate proximity
(the area within its sensing range). For the purpose of sensing an
area of interest, there are adequate number of fixed sensor
nodes required to cover the entire region of interest. It implies
that the number of fixed sensor nodes required to cover a given
area will depend on the sensing range of the sensor as well as
deployment strategies employed. It is assumed that the sensors to
be mobile within the region of surveillance, can be mounted on
moving bodies like robots or vehicle. Therefore, in our
scheme, the surveillance time period determines the number of
sensor nodes required to be deployed in the region of interest.
The proposed scheme comprises of three algorithms namely:
Hexagonalization, Clustering, and Scheduling, The first algorithm
partitions the coverage area into fixed sized hexagons that
approximate the sensing range (cell) of individual sensor node.
The clustering algorithm groups the cells into clusters, each of
which will be covered by a single sensor node. The later
determines a schedule for each sensor to serve its respective cluster.
Each sensor node traverses all the cells belonging to the cluster
assigned to it by oscillating between the first and the last cell for
the duration of its life time. Simulation results show that our
scheme provides full coverage within a given period of time using
few sensors with minimum movement, less power consumption,
and relatively less infrastructure cost.
Abstract: Two optimized strategies were successfully established
to develop biomolecule-based magnetic nanoassemblies.
Streptavidin-coated and amine-coated magnetic nanoparticles were
chosen as model scaffolds onto which double-stranded DNA and
human immunoglobulin G were specifically conjugated in succession,
using biotin-streptavidin interaction or covalent cross-linkers. The
success of this study opens the prospect of developing selective and
sensitive nanoparticle-based structures for diagnostics or drug
delivery.
Abstract: The goal of speech parameterization is to extract the relevant information about what is being spoken from the audio signal. In speech recognition systems Mel-Frequency Cepstral Coefficients (MFCC) and Relative Spectral Mel-Frequency Cepstral Coefficients (RASTA-MFCC) are the two main techniques used. It will be shown in this paper that it presents some modifications to the original MFCC method. In our work the effectiveness of proposed changes to MFCC called Modified Function Cepstral Coefficients (MODFCC) were tested and compared against the original MFCC and RASTA-MFCC features. The prosodic features such as jitter and shimmer are added to baseline spectral features. The above-mentioned techniques were tested with impulsive signals under various noisy conditions within AURORA databases.
Abstract: The hard clam (meretrix lusoria) cultivated industry
has been developed vigorously for recent years in Taiwan, and
seawater quality determines the cultivated environment. The pH
concentration variation affects survival rate of meretrix lusoria
immediately. In order to monitor seawater quality, solid-state sensing
electrode of ruthenium-doped titanium dioxide (TiO2:Ru) is developed
to measure hydrogen ion concentration in different cultivated
solutions. Because the TiO2:Ru sensing electrode has high chemical
stability and superior sensing characteristics, thus it is applied as a pH
sensor. Response voltages of TiO2:Ru sensing electrode are readout by
instrument amplifier in different sample solutions. Mean sensitivity
and linearity of TiO2:Ru sensing electrode are 55.20 mV/pH and 0.999
from pH1 to pH13, respectively. We expect that the TiO2:Ru sensing
electrode can be applied to real environment measurement, therefore
we collect two sample solutions by different meretrix lusoria
cultivated ponds in the Yunlin, Taiwan. The two sample solutions are
both measured for 200 seconds after calibration of standard pH buffer
solutions (pH7, pH8 and pH 9). Mean response voltages of sample 1
and sample 2 are -178.758 mV (Standard deviation=0.427 mV) and
-180.206 mV (Standard deviation =0.399 mV), respectively. Response
voltages of the two sample solutions are between pH 8 and pH 9 which
conform to weak alkali range and suitable meretrix lusoria growth. For
long-term monitoring, drift of cultivated solutions (sample 1 and
sample 2) are 1.16 mV/hour and 1.03 mV/hour, respectively.
Abstract: Confucius was a fifth-century BCE Chinese thinker whose influence upon East Asian intellectual and social history is immeasurable. Better known is in China as “Master Kong”. As a culturally symbolic figure, he has been alternately idealized, deified, dismissed, vilified, and rehabilitated over the millennia by both Asian and non-Asian thinkers and regimes. Given his extraordinary impact on Chinese, Korean, Japanese, and Vietnamese thought, it is ironic that so little can be known about Confucius. The tradition that bears his name – “Confucianizm” (Chinese: Rujia) – ultimately traces itself to the sayings and biographical fragments recorded in the text known as the Analects (Chinese: Lunyu). In the Analects, two types of persons are opposed to one another – not in terms of basic potential, but in terms of developed potential. These are the junzi (literally, “lord’s son” or “gentleman”) and the xiaoren (“small person”). The junzi is the person who always manifests the quality of ren in his
person and the displays the quality of lee in his actions. In this article examines the category of the ideal man and the spiritual and moral values of the philosophy of Confucius. According to Confucius high-morality Jun-zi is characterized by two things: a sense of humanity and duty. This article provides an analysis of the ethical category for the ideal man.
Abstract: This study examined the toxicological effects and
safety of polypeptide k isolated from the seeds of Momordica
charantia in laboratory rats. 30 male Sprague Dawley rats (12 weeks
old, bodyweight 180-200 g) were randomly divided into 3 groups
(1000 mg/kg, 500 mg and 0 mg/kg). Rats were acclimatized to
laboratory conditions for 7 days and at day 8 rats were dosed orally
with polypeptide k (in 2% DMSO/normal saline) and the controls
received the dosed vehicle only. Rats were then observed for 72
hours before sacrificed. Rats were anaesthetized by pentobarbital
(50 mg/kg ip) and 2-3.0 mL of blood was taken by cardiac puncture
and rats were scarified by anaesthetic overdose. Immediately, organs
(heart, lungs, liver, kidneys) were weigh and taken for histology.
Organ sections were then evaluated by a histopathologist. Serum
samples were assayed for liver functions (ALT and γ-GT) and kidney
functions (BUN and creatinine). All rats showed normal behavior
after the dosing and no statistical changes were observed in all blood
parameters and organ weight. Histological examinations revealed
normal organ structures. In conclusion, dosing of rats up to 1000
mg/kg did not have any effects on the rat behavior, liver or kidney
functions nor histology of the selected organs.
Abstract: The Merrifield-Simmons index of a graph G is defined as the total number of its independent sets. A (n, n + 2)-graph is a connected simple graph with n vertices and n + 2 edges. In this paper we characterize the (n, n+2)-graph with the largest Merrifield- Simmons index. We show that its Merrifield-Simmons index i.e. the upper bound of the Merrifield-Simmons index of the (n, n+2)-graphs is 9 × 2n-5 +1 for n ≥ 5.
Abstract: In a 10-week (May – August, 2008) Phase I trial, 840, 1+ rainbow trout, Oncorhynchus mykiss, received a commercial oral immunomodulator, Fin Immune™, at four different dosages (0, 10, 20 and 30 mg g-1) to evaluate immune response and growth. The overall objective of was to determine an optimal dosage of this product for rainbow trout that provides enhanced immunity with maximal growth and health. Biweekly blood samples were taken from 10 randomly selected fish in each tank (30 samples per treatment) to evaluate the duration of enhanced immunity conferred by Fin-Immune™. The immunological assessment included serum white blood cell (lymphocyte, neutrophil) densities and blood hematocrit (packed cell volume %). Of these three variables, only lymphocyte density increased significantly among trout fed Fin- Immune™ at 20 and 30 mg g-1 which peaked at week 6. At week 7, all trout were switched to regular feed (lacking Fin-Immune™) and by week 10, lymphocyte levels decreased among all levels but were still greater than at week 0. There was growth impairment at the highest dose of Fin-Immune™ tested (30 mg g-1) which can be associated with a physiological compensatory mechanism due to a dose-specific threshold level. Thus, our main objective of this Phase I study was achieved, the 20 mg g-1 dose of Fin-Immune™ should be the most efficacious (of those we tested) to use for a Phase II disease challenge trial.