Abstract: The adsorption of bovine serum albumin (BSA), immunoglobulin G (IgG) and fibrinogen (Fgn) on fluorinated selfassembled monolayers have been studied using time of flight secondary ion mass spectrometry (ToF-SIMS) and Spectroscopic Ellipsometry (SE). The objective of the work has to establish the utility of ToF-SIMS for the determination of the amount of protein adsorbed on the surface. Quantification of surface adsorbed proteins was carried out using SE and a good correlation between ToF-SIMS results and SE was achieved. The surface distribution of proteins were also analysed using Atomic Force Microscopy (AFM). We show that the surface distribution of proteins strongly affect the ToFSIMS results.
Abstract: In this paper a comprehensive algorithm is presented to alleviate the undesired simultaneous effects of target maneuvering, observed glint noise distribution, and colored noise spectrum using online colored glint noise parameter estimation. The simulation results illustrate a significant reduction in the root mean square error (RMSE) produced by the proposed algorithm compared to the algorithms that do not compensate all the above effects simultaneously.
Abstract: Hepatitis B and hepatitis C are among the most
significant hepatic infections all around the world that may lead to
hepatocellular carcinoma. This study is first time performed at the
blood transfussion centre of Omar hospital, Lahore. It aims to
determine the sero-prevalence of these diseases by screening the
apparently healthy blood donors who might be the carriers of HBV or
HCV and pose a high risk in the transmission. It also aims the
comparison between the sensitivity of two diagnostic tests;
chromatographic immunoassay – one step test device and Enzyme
Linked Immuno Sorbant Assay (ELISA). Blood serum of 855
apparently healthy blood donors was screened for Hepatitis B surface
antigen (HBsAg) and for anti HCV antibodies. SPSS version 12.0
and X2 (Chi-square) test were used for statistical analysis. The seroprevalence
of HCV was 8.07% by the device method and by ELISA
9.12% and that of HBV was 5.6% by the device and 6.43% by
ELISA. The unavailability of vaccination against HCV makes it more
prevalent. Comparing the two diagnostic methods, ELISA proved to
be more sensitive.
Abstract: This interdisciplinary research aims to distinguish universal scale-free and field-like fundamental principles of selforganization observable across many disciplines like computer science, neuroscience, microbiology, social science, etc. Based on these universal principles we provide basic premises and postulates for designing holistic social simulation models. We also introduce pervasive information field (PIF) concept, which serves as a simulation media for contextual information storage, dynamic distribution and organization in social complex networks. PIF concept specifically is targeted for field-like uncoupled and indirect interactions among social agents capable of affecting and perceiving broadcasted contextual information. Proposed approach is expressive enough to represent contextual broadcasted information in a form locally accessible and immediately usable by network agents. This paper gives some prospective vision how system-s resources (tangible and intangible) could be simulated as oscillating processes immersed in the all pervasive information field.
Abstract: In an emergency, combining Wireless Sensor Network's data with the knowledge gathered from various other information sources and navigation algorithms, could help safely guide people to a building exit while avoiding the risky areas. This paper presents an emergency response and navigation support architecture for data gathering, knowledge manipulation, and navigational support in an emergency situation. At normal state, the system monitors the environment. When an emergency event detects, the system sends messages to first responders and immediately identifies the risky areas from safe areas to establishing escape paths. The main functionalities of the system include, gathering data from a wireless sensor network which is deployed in a multi-story indoor environment, processing it with information available in a knowledge base, and sharing the decisions made, with first responders and people in the building. The proposed architecture will act to reduce risk of losing human lives by evacuating people much faster with least congestion in an emergency environment.
Abstract: Nowadays, more engineering systems are using some
kind of Artificial Intelligence (AI) for the development of their
processes. Some well-known AI techniques include artificial neural
nets, fuzzy inference systems, and neuro-fuzzy inference systems
among others. Furthermore, many decision-making applications base
their intelligent processes on Fuzzy Logic; due to the Fuzzy
Inference Systems (FIS) capability to deal with problems that are
based on user knowledge and experience. Also, knowing that users
have a wide variety of distinctiveness, and generally, provide
uncertain data, this information can be used and properly processed
by a FIS. To properly consider uncertainty and inexact system input
values, FIS normally use Membership Functions (MF) that represent
a degree of user satisfaction on certain conditions and/or constraints.
In order to define the parameters of the MFs, the knowledge from
experts in the field is very important. This knowledge defines the MF
shape to process the user inputs and through fuzzy reasoning and
inference mechanisms, the FIS can provide an “appropriate" output.
However an important issue immediately arises: How can it be
assured that the obtained output is the optimum solution? How can it
be guaranteed that each MF has an optimum shape? A viable solution
to these questions is through the MFs parameter optimization. In this
Paper a novel parameter optimization process is presented. The
process for FIS parameter optimization consists of the five simple
steps that can be easily realized off-line. Here the proposed process
of FIS parameter optimization it is demonstrated by its
implementation on an Intelligent Interface section dealing with the
on-line customization / personalization of internet portals applied to
E-commerce.
Abstract: Ascorbic acid (AA), commonly known as vitamin C, is essential for normal functioning of the body and maintenance of metabolic integrity. Among its various roles are as an antioxidant, a cofactor in collagen formation and other reactions, as well as reducing physical stress and maintenance of the immune system. Recent collaborative research between the Australian Defence Science and Technology Organisation (DSTO) in Scottsdale, Tasmania and RMIT University has sought to overcome the problems arising from the inherent instability of ascorbic acid during processing and storage of foods. The recent work has demonstrated the potential of microencapsulation by spray drying as a means to enhance retention. The purpose of this current study has been focused upon the influence of spray drying conditions on the properties of encapsulated ascorbic acid. The process was carried out according to a central composite design. Independent variables were: inlet temperature (80-120° C) and feed flow rate (7-14 mL/minute). Process yield, ascorbic acid loss, moisture content, water activity and particle size distribution were analysed as responses. The results have demonstrated the potential of microencapsulation by spray drying as a means to enhance retention. Vitamin retention, moisture content, water activity and process yield were influenced positively by inlet air temperature and negatively by feed flow rate.
Abstract: The freezing point of milk is in important indicator of
the milk quality. The freezing point of milk is determined primarily
to prove milk adulteration with water and to determine the amount of
water in it. Chemical composition and properties of milk, thermal
treatment and presence of any substance can influence freezing point
of product. There are different substances, which can be added to
milk with main purpose to prolong shelf-life of raw milk. There are
detergent, preservatives, formaldehyde, hydrogen peroxide,
antibiotics, sodium carbonate, and hydrogen peroxide. Therefore the
aim of the present study was to determine freezing point of milk,
skimmed milk, pasteurized milk and milk with different substances
(formaldehyde, antibiotics, sodium carbonate, hydrogen peroxide,
disinfectant, and detergent) in different concentrations. The thermal
treatment and different undesirable substances presence in milk have
significant influence on freezing point of it.
Abstract: Preparation of hydrogel based on carrageenan
extracted from Kappaphycus alvarezii was conducted with film
immersion in glutaraldehyde solution (GA 4%w/w) for 2min and
then followed by thermal curing at 110°C for 25min. The method of
carrageenan recovery strongly determines the properties of
crosslinked carrageenan. Hydrogel obtained from alkali treated
carrageenan showed higher swelling ability compared to hydrogel
from nonalkali treated carrageenan. Hydrogel from alkali treated
showed the ability of sensitive to pH media.
Abstract: Synchronous cooperative systems (SCS) bring together users that are geographically distributed and connected through a network to carry out a task. Examples of SCS include Tele- Immersion and Tele-Conferences. In SCS, the coordination is the core of the system, and it has been defined as the act of managing interdependencies between activities performed to achieve a goal. Some of the main problems that SCS present deal with the management of constraints between simultaneous activities and the execution ordering of these activities. In order to resolve these problems, orderings based on Lamport-s happened-before relation have been used, namely, causal, Δ-causal, and causal-total orderings. They mainly differ in the degree of asynchronous execution allowed. One of the most important orderings is the causal order, which establishes that the events must be seen in the cause-effect order as they occur in the system. In this paper we show that for certain SCS (e.g. videoconferences, tele-immersion) where some degradation of the system is allowed, ensuring the causal order is still rigid, which can render negative affects to the system. In this paper, we illustrate how a more relaxed ordering, which we call Fuzzy Causal Order (FCO), is useful for such kind of systems by allowing a more asynchronous execution than the causal order. The benefit of the FCO is illustrated by applying it to a particular scenario of intermedia synchronization of an audio-conference system.
Abstract: This paper presents results of an experimental study performed to investigate effect of incorporating silica fume on physico-mechanical properties and durability of resulting fly ash geopolymers. Geopolymer specimens were prepared by activating fly ash incorporated with additional silica fume in the range of 2.5% to 5%, with a mixture of sodium hydroxide and sodium silicate solution having Na2O content of 8%. For studying durability, 10% magnesium sulphate solution was used to immerse the specimens up to a period of 15 weeks during which visual observation, weight changes and strength changes were monitored regularly. Addition of silica fume lowers performance of geopolymer pastes. However, in mortars, addition of silica fume significantly enhanced physico-mechanical properties and durability.
Abstract: The steady coupled dissipative layers, called
Marangoni mixed convection boundary layers, in the presence of a
magnetic field and solute concentration that are formed along the
surface of two immiscible fluids with uniform suction or injection
effects is examined. The similarity boundary layer equations are
solved numerically using the Runge-Kutta Fehlberg with shooting
technique. The Marangoni, buoyancy and external pressure gradient
effects that are generated in mixed convection boundary layer flow
are assessed. The velocity, temperature and concentration boundary
layers thickness decrease with the increase of the magnetic field
strength and the injection to suction. For buoyancy-opposed flow, the
Marangoni mixed convection parameter enhances the velocity
boundary layer but decreases the temperature and concentration
boundary layers. However, for the buoyancy-assisted flow, the
Marangoni mixed convection parameter decelerates the velocity but
increases the temperature and concentration boundary layers.
Abstract: In this work, sorption of nickel from aqueous solution on hypnea valentiae, red macro algae, was investigated. Batch experiments have been carried out to find the effect of various parameters such as pH, temperature, sorbent dosage, metal concentration and contact time on the sorption of nickel using hypnea valentiae. Response surface methodology (RSM) is employed to optimize the process parameters. Based on the central composite design, quadratic model was developed to correlate the process variables to the response. The most influential factor on each experimental design response was identified from the analysis of variance (ANOVA). The optimum conditions for the sorption of nickel were found to be: pH – 5.1, temperature – 36.8oC, sorbent dosage – 5.1 g/L, metal concentration – 100 mg/L and contact time – 30 min. At these optimized conditions the maximum removal of nickel was found to be 91.97%. A coefficient of determination R2 value 0.9548 shows the fitness of response surface methodology in this work.
Abstract: Nano fibers produced by electrospinning are of industrial and scientific attention due to their special characteristics such as long length, small diameter and high surface area. Applications of electrospun structures in nanotechnology are included tissue scaffolds, fibers for drug delivery, composite reinforcement, chemical sensing, enzyme immobilization, membrane-based filtration, protective clothing, catalysis, solar cells, electronic devices and others. Many polymer and ceramic precursor nano fibers have been successfully electrospun with diameters in the range from 1 nm to several microns. The process is complex so that fiber diameter is influenced by various material, design and operating parameters. The objective of this work is to apply genetic algorithm on the parameters of electrospinning which have the most significant effect on the nano fiber diameter to determine the optimum parameter values before doing experimental set up. Effective factors including initial polymer concentration, initial jet radius, electrical potential, relaxation time, initial elongation, viscosity and distance between nozzle and collector are considered to determine finest diameter which is selected by user.
Abstract: The ongoing effort to develop an in-house
compressible solver with multi-disciplinary physics is presented in
this paper. Basic compressible solver combined with IBM technique
provides us an effective numerical tool able to tackle the physics
phenomena and especially physic phenomena involved in Solid
Rocket Motors (SRMs). Main principles are introduced step by step
describing its implementation. This paper sheds light on the whole
potentiality of our proposed numerical model and we strongly believe
a way to introduce multi-physics mechanisms strongly coupled is
opened to ablation in nozzle, fluid/structure interaction and burning
propellant surface with time.
Abstract: In the present study, computational fluid dynamics
(CFD) simulation has been executed to investigate the transition
boundaries of different flow patterns for moderately viscous oil-water
(viscosity ratio 107, density ratio 0.89 and interfacial tension of 0.032
N/m.) two-phase flow through a horizontal pipeline with internal
diameter and length of 0.025 m and 7.16 m respectively. Volume of
Fluid (VOF) approach including effect of surface tension has been
employed to predict the flow pattern. Geometry and meshing of the
present problem has been drawn using GAMBIT and ANSYS
FLUENT has been used for simulation. A total of 47037 quadrilateral
elements are chosen for the geometry of horizontal pipeline. The
computation has been performed by assuming unsteady flow,
immiscible liquid pair, constant liquid properties, co-axial flow and a
T-junction as entry section. The simulation correctly predicts the
transition boundaries of wavy stratified to stratified mixed flow.
Other transition boundaries are yet to be simulated. Simulated data
has been validated with our own experimental results.
Abstract: Mycophenolic acid (MPA) is a secondary metabolite
produced by Penicillium brevicompactum, which has antibiotic and
immunosuppressive properties. In this study, the first, mycophenolic
acid was produced in a fermentation process by Penicillium
brevicompactum MUCL 19011 in shake flask using a base medium.
The maximum MPA production, product yield and productivity of
process were 1.379 g/L, 18.6 mg/g glucose and 4.9 mg/L. h,
respectively. Also the glucose consumption, biomass and MPA
production profiles were investigated during batch cultivation.
Obtained results showed that MPA production starts approximately
after 180 hours and reaches to a maximum at 280 h. In the next step,
the effects of some various concentrations of enzymatically
hydrolyzed casein on MPA production were evaluated. Maximum
MPA production, product yield and productivity as 3.63 g/L, 49
mg/g glucose and 12.96 mg/L.h, respectively were obtained with
using 30 g/L enzymatically hydrolyzed casein in culture medium.
These values show an enhanced MPA production, product yield and
process productivity pr as 116.8%, 132.8% and 163.2%, respectively.
Abstract: Nowadays, keyless entry systems are widely adopted
for vehicle immobilizer systems due to both advantages of security and
convenience. Keyless entry systems could overcome brute-force key
guessing attack, statistics attack and masquerade attack, however,
they can't prevent from thieves stealing behavior. In this paper, we
proposed a new architecture try to improve the existent flaws. The
integration of the keyless entry system and the fingerprint
identification technology is more suitable to implement on the
portable transponder to achieve higher security needs. We also adopt
and modify AES security protocol for life expectancy and security of
the portable transponder. In addition, the identification of a driver's
fingerprint makes the service of automatic reinstatement of a driver's
preferences become possible. Our design can satisfy not only the three
kinds of previous illegal attacks, but also the stealing situation.
Furthermore, many practical factors, such as costs, life expectancy and
performance, have been well considered in the design of portable
transponder.
Abstract: Celiac disease is an immune-mediated disease, triggered in genetically susceptible individuals by ingested gluten from wheat, rye, barley and other closely related cereal grains. The only effective treatment is a strict gluten free diet for life. Latvian producers do not offer gluten-free products. In this research, use of extruded maize flour was tested for substituting rice, maize or buckwheat flour in gluten-free bread formulations at different ratios. Also the influence of extruded maize flour on the quality parameters of gluten-free bread was investigated. The aim of research was to study the influence of extruded maize flour on gluten-free bread quality. Addition of extruded maize flour affect gluten-free bread crumb color, structure of crumb, weight loss and dry off of bread.
Abstract: Despite the fact that Knowledge Sharing (KS) is very important, we found only little discussion about the reasons why people have the willingness to share knowledge at such platform even though there is no immediate benefit to the persons who contribute knowledge in it. The aim of this study is to develop an integrative understanding of the factors that support or inhibit individuals- knowledge sharing intentions in virtual communities and to find whether habit would generate people-s willingness to be involved. We apply Social Capital Theory (SCT), and we also add two dimensions for discussion: member incentive and habitual domain (HD). This research assembles the questionnaire from individuals who have experienced knowledge sharing in virtual communities, and applies survey and Structural Equation Model (SEM) to analyze the results from the questionnaires. Finally, results confirm that individuals are willing to share knowledge in virtual communities: (1) if they consider reciprocity, centrality, and have longer tenure in their field, and enjoy helping. (2) if they have the habit of sharing knowledge. This study is useful for the developers of virtual communities to insight into knowledge sharing in cyberspace.