Abstract: This research tested the performance of alternative
warehouse designs concerning the picking process. The chosen
performance measures were Travel Distance and Total Fulfilment
Time. An explanatory case study was built up around a model
implemented with SIMUL8. Hypotheses were set by selecting
outcomes from the literature survey matching popular empirical
findings. 17.4% reductions were found for Total Fulfilment Time and
Resource Utilisation. The latter was then used as a proxy for
operational efficiency. Literal replication of theoretical data-patterns
was considered as an internal validity sign. Assessing the estimated
changes benefits ahead of implementation was found to be a
contribution to practice.
Abstract: Recent investigations have demonstrated the global
sea level rise due to climate change impacts. In this study, climate
changes study the effects of increasing water level in the strait of
Hormuz. The probable changes of sea level rise should be
investigated to employ the adaption strategies. The climatic output
data of a GCM (General Circulation Model) named CGCM3 under
climate change scenario of A1b and A2 were used. Among different
variables simulated by this model, those of maximum correlation
with sea level changes in the study region and least redundancy
among themselves were selected for sea level rise prediction by using
stepwise regression. One of models (Discrete Wavelet artificial
Neural Network) was developed to explore the relationship between
climatic variables and sea level changes. In these models, wavelet
was used to disaggregate the time series of input and output data into
different components and then ANN was used to relate the
disaggregated components of predictors and input parameters to each
other. The results showed in the Shahid Rajae Station for scenario
A1B sea level rise is among 64 to 75 cm and for the A2 Scenario sea
level rise is among 90 t0 105 cm. Furthermore, the result showed a
significant increase of sea level at the study region under climate
change impacts, which should be incorporated in coastal areas
management.
Abstract: The ultimate purpose of this investigation was to
determine the teachers’ opinions as well as students’ opinions
towards the Adapted English Lessons. The subjects of the study were
5 Thai teachers, who teach English, and 85 Grade 10 mixed-ability
students at Triamudom Suksa Pattanakarn Ratchada School,
Bangkok, Thailand. The research instruments included questionnaires
and the informal interview. The data from the research instruments
was collected and analyzed concerning linguistic principles of
minimal pair and articulatory phonetics as well as teaching
techniques of mimicry-memorization; vocabulary substitution drills,
language pattern drills, reading comprehension exercise, practicing
listening, speaking and writing skill and communicative activities;
informal talk and free writing. The data was statistically compiled
according to an arithmetic percentage. The results showed that the
teachers and students have very highly positive opinions towards
adapting linguistic principles for teaching and learning phonological
accuracy. Teaching techniques provided in the Adapted English
Lessons can be used efficiently in the classroom. The teachers and
students have positive opinions towards them too.
Abstract: Targeted drug delivery is a method of delivering
medication to a patient in a manner that increases the concentration
of the medication in some parts of the body relative to others.
Targeted drug delivery seeks to concentrate the medication in the
tissues of interest while reducing the relative concentration of the
medication in the remaining tissues. This improves efficacy of the
while reducing side effects. In the present work, we investigate the
effect of magnetic field, flow rate and particle concentration on the
capturing of magnetic particles transported in a stent implanted
fluidic channel. Iron oxide magnetic nanoparticles (Fe3O4)
nanoparticles were synthesized via co-precipitation method. The
synthesized Fe3O4 nanoparticles were added in the de-ionized (DI)
water to prepare the Fe3O4 magnetic particle suspended fluid. This
fluid is transported in a cylindrical tube of diameter 8 mm with help
of a peristaltic pump at different flow rate (25-40 ml/min). A
ferromagnetic coil of SS 430 has been implanted inside the
cylindrical tube to enhance the capturing of magnetic nanoparticles
under magnetic field. The capturing of magnetic nanoparticles was
observed at different magnetic magnetic field, flow rate and particle
concentration. It is observed that capture efficiency increases from
47-67% at magnetic field 2-5kG, respectively at particle
concentration 0.6mg/ml and at flow rate 30 ml/min. However, the
capture efficiency decreases from 65 to 44% by increasing the flow
rate from 25 to 40 ml/min, respectively. Furthermore, it is observed
that capture efficiency increases from 51 to 67% by increasing the
particle concentration from 0.3 to 0.6 mg/ml, respectively.
Abstract: In this glasshouse study, we developed a new imagebased
non-destructive technique for detecting leaf P status of
different crops such as cotton, tomato and lettuce. The plants were
grown on a nutrient solution containing different P concentrations,
e.g. 0%, 50% and 100% of recommended P concentration (P0 = no P,
L; P1 = 2.5 mL 10 L-1 of P and P2 = 5 mL 10 L-1 of P). After 7 weeks
of treatment, the plants were harvested and data on leaf P contents
were collected using the standard destructive laboratory method and
at the same time leaf images were collected by a handheld crop image
sensor. We calculated leaf area, leaf perimeter and RGB (red, green
and blue) values of these images. These data were further used in
linear discriminant analysis (LDA) to estimate leaf P contents, which
successfully classified these plants on the basis of leaf P contents.
The data indicated that P deficiency in crop plants can be predicted
using leaf image and morphological data. Our proposed nondestructive
imaging method is precise in estimating P requirements of
different crop species.
Abstract: The objective of this study was to synthesize and
characterize the poly(alkenoic acid)s with different molecular
structures, use these polymers to formulate a dental cement
restorative, and study the effect of molecular structures on reaction
kinetics, viscosity, and mechanical strengths of the formed polymers
and cement restoratives. In this study, poly(alkenoic acid)s with
different molecular structures were synthesized. The purified
polymers were formulated with commercial Fuji II LC glass fillers to
form the experimental cement restoratives. The reaction kinetics was
studied via 1HNMR spectroscopy. The formed restoratives were
evaluated using compressive strength, diametral tensile strength,
flexural strength, hardness and wear-resistance tests. Specimens were
conditioned in distilled water at 37oC for 24 h prior to testing. Fuji II
LC restorative was used as control. The results show that the higher
the arm number and initiator concentration, the faster the reaction
was. It was also found that the higher the arm number and branching
that the polymer had, the lower the viscosity of the polymer in water
and the lower the mechanical strengths of the formed restorative. The
experimental restoratives were 31-53% in compressive strength, 37-
55% in compressive modulus, 80-126% in diametral tensile strength,
76-94% in flexural strength, 4-21% in fracture toughness and 53-96%
in hardness higher than Fuji II LC. For wear test, the experimental
restoratives were only 5.4-13% of abrasive and 6.4-12% of attritional
wear depths of Fuji II LC in each wear cycle. The aging study also
showed that all the experimental restoratives increased their strength
continuously during 30 days, unlike Fuji II LC. It is concluded that
polymer molecular structures have significant and positive impact on
mechanical properties of dental cement restoratives.
Abstract: Pure nickel coatings have been successfully
electrodeposited on copper substrates by the pulse plating technique.
The influence of current density, duty cycle and pulse frequency on
the surface morphology, crystal orientation, and microhardness was
determined. It was found that the crystallite size of the deposit
increases with increasing current density and duty cycle. The crystal
orientation progressively changed from a random texture at 1 A/dm2
to (200) texture at 10 A/dm2. Increasing pulse frequency resulted in
increased texture coefficient and peak intensity of (111) reflection.
An increase in duty cycle resulted in considerable increase in texture
coefficient and peak intensity of (311) reflection. Coatings obtained
at high current densities and duty cycle present a mixed morphology
of small and large grains. Maximum microhardness of 193 Hv was
achieved at 4 A/dm2, 10 Hz and duty cycle of 50%. Nickel coatings
with (200) texture are ductile while (111) texture improves the
microhardness of the coatings.
Abstract: Introduction: The process to build a better safety
culture, methods of error analysis, and preventive measures, starts
with an understanding of the effects when human factors engineering
refer to remote microscopic diagnosis in surgery and specially in
organ transplantation for the remote evaluation of the grafts. It has
been estimated that even in well-organized transplant systems an
average of 8% to 14% of the grafts (G) that arrive at the recipient
hospitals may be considered as diseased, injured, damaged or
improper for transplantation. Digital microscopy adds information on
a microscopic level about the grafts in Organ Transplant (OT), and
may lead to a change in their management. Such a method will
reduce the possibility that a diseased G, will arrive at the recipient
hospital for implantation. Aim: Ergonomics of Digital Microscopy
(DM) based on virtual slides, on Telemedicine Systems (TS) for
Tele-Pathological (TPE) evaluation of the grafts (G) in organ
transplantation (OT). Material and Methods: By experimental
simulation, the ergonomics of DM for microscopic TPE of Renal
Graft (RG), Liver Graft (LG) and Pancreatic Graft (PG) tissues is
analyzed. In fact, this corresponded to the ergonomics of digital
microscopy for TPE in OT by applying Virtual Slide (VS) system for
graft tissue image capture, for remote diagnoses of possible
microscopic inflammatory and/or neoplastic lesions. Experimentation
included: a. Development of an OTE-TS similar Experimental
Telemedicine System (Exp.-TS), b. Simulation of the integration of
TS with the VS based microscopic TPE of RG, LG and PG applying
DM. Simulation of the DM based TPE was performed by 2
specialists on a total of 238 human Renal Graft (RG), 172 Liver Graft
(LG) and 108 Pancreatic Graft (PG) tissues digital microscopic
images for inflammatory and neoplastic lesions on four electronic
spaces of the four used TS. Results: Statistical analysis of specialist‘s
answers about the ability to diagnose accurately the diseased RG, LG
and PG tissues on the electronic space among four TS (A,B,C,D)
showed that DM on TS for TPE in OT is elaborated perfectly on the
ES of a Desktop, followed by the ES of the applied Exp.-TS. Tablet
and Mobile-Phone ES seem significantly risky for the application of
DM in OT (p
Abstract: Lateral torsional buckling is a global buckling mode
which should be considered in design of slender structural members
under flexure about their strong axis. It is possible to compute the
load which causes lateral torsional buckling of a beam by finite
element analysis, however, closed form equations are needed in
engineering practice for calculation ease which can be obtained by
using energy method. In lateral torsional buckling applications of
energy method, a proper function for the critical lateral torsional
buckling mode should be chosen which can be thought as the
variation of twisting angle along the buckled beam. Accuracy of the
results depends on how close is the chosen function to the exact
mode. Since critical lateral torsional buckling mode of the cantilever
I-beams varies due to material properties, section properties and
loading case, the hardest step is to determine a proper mode function
in application of energy method. This paper presents an approximate function for critical lateral
torsional buckling mode of doubly symmetric cantilever I-beams.
Coefficient matrices are calculated for concentrated load at free end,
uniformly distributed load and constant moment along the beam
cases. Critical lateral torsional buckling modes obtained by presented
function and exact solutions are compared. It is found that the modes
obtained by presented function coincide with differential equation
solutions for considered loading cases.
Abstract: In this study, a general approach to the reliability
based limit analysis of laterally loaded piles is presented. In
engineering practice the uncertainties play a very important role. The
aim of this study is to evaluate the lateral load capacity of free-head
and fixed-head long pile when plastic limit analysis is considered. In
addition to the plastic limit analysis to control the plastic behaviour
of the structure, uncertain bound on the complementary strain energy
of the residual forces is also applied. This bound has significant effect
for the load parameter. The solution to reliability-based problems is
obtained by a computer program which is governed by the reliability
index calculation.
Abstract: Cancer is still one of the serious diseases threatening
the lives of human beings. How to have an early diagnosis and
effective treatment for tumors is a very important issue. The animal
carcinoma model can provide a simulation tool for the studies of
pathogenesis, biological characteristics, and therapeutic effects.
Recently, drug delivery systems have been rapidly developed to
effectively improve the therapeutic effects. Liposome plays an
increasingly important role in clinical diagnosis and therapy for
delivering a pharmaceutic or contrast agent to the targeted sites.
Liposome can be absorbed and excreted by the human body, and is
well known that no harm to the human body. This study aimed to
compare the therapeutic effects between encapsulated (doxorubicin
liposomal, Lipodox) and un-encapsulated (doxorubicin, Dox)
anti-tumor drugs using magnetic resonance imaging (MRI).
Twenty-four New Zealand rabbits implanted with VX2 carcinoma at
left thighs were classified into three groups: control group (untreated),
Dox-treated group, and LipoDox-treated group, 8 rabbits for each
group. MRI scans were performed three days after tumor implantation.
A 1.5T GE Signa HDxt whole body MRI scanner with a high
resolution knee coil was used in this study. After a 3-plane localizer
scan was performed, three-dimensional (3D) fast spin echo (FSE)
T2-weighted Images (T2WI) was used for tumor volumetric
quantification. Afterwards, two-dimensional (2D) spoiled gradient
recalled echo (SPGR) dynamic contrast-enhanced (DCE) MRI was
used for tumor perfusion evaluation. DCE-MRI was designed to
acquire four baseline images, followed by contrast agent Gd-DOTA
injection through the ear vein of rabbit. A series of 32 images were
acquired to observe the signals change over time in the tumor and
muscle. The MRI scanning was scheduled on a weekly basis for a
period of four weeks to observe the tumor progression longitudinally.
The Dox and LipoDox treatments were prescribed 3 times in the first
week immediately after the first MRI scan; i.e. 3 days after VX2 tumor
implantation. ImageJ was used to quantitate tumor volume and time
course signal enhancement on DCE images. The changes of tumor size
showed that the growth of VX2 tumors was effectively inhibited for
both LipoDox-treated and Dox-treated groups. Furthermore, the tumor
volume of LipoDox-treated group was significantly lower than that of
Dox-treated group, which implies that LipoDox has better therapeutic effect than Dox. The signal intensity of LipoDox-treated group is
significantly lower than that of the other two groups, which implies
that targeted therapeutic drug remained in the tumor tissue. This study
provides a radiation-free and non-invasive MRI method for
therapeutic monitoring of targeted liposome on an animal tumor
model.
Abstract: Underwater acoustic networks have attracted great
attention in the last few years because of its numerous applications.
High data rate can be achieved by efficiently modeling the physical
layer in the network protocol stack. In Acoustic medium,
propagation speed of the acoustic waves is dependent on many
parameters such as temperature, salinity, density, and depth.
Acoustic propagation speed cannot be modeled using standard
empirical formulas such as Urick and Thorp descriptions. In this
paper, we have modeled the acoustic channel using real time data of
temperature, salinity, and speed of Bay of Bengal (Indian Coastal
Region). We have modeled the acoustic channel by using Mackenzie
speed equation and real time data obtained from National Institute of
Oceanography and Technology. It is found that acoustic propagation
speed varies between 1503 m/s to 1544 m/s as temperature and
depth differs. The simulation results show that temperature, salinity,
depth plays major role in acoustic propagation and data rate
increases with appropriate data sets substituted in the simulated
model.
Abstract: Fires is one of the main types of disturbances that
shape ecosystems in the Mediterranean region. However nowadays,
climate alterations towards higher temperatures result on increased
levels of fire intensity, frequency and spread as well as difficulties for
natural regeneration to occur. Thasos Island is one of the Greek
islands that has experienced those problems. Since 1984, a series of
wildfires led to the reduction of forest cover from 61.6% to almost
20%. The negative impacts were devastating in many different
aspects for the island. The absence of plant cover, post-wildfire
precipitation and steep slopes were the major factors that induced
severe soil erosion and intense floods. That also resulted to serious
economic problems to the local communities and the inability of the
burnt areas to regenerate naturally. Despite the substantial amount of
published work regarding Thasos wildfires, there is no information
related to post-wildfire effects on factors such as soil erosion. More
research related to post-fire effects should help to an overall
assessment of the negative impacts of wildfires on land degradation
through processes such as soil erosion and flooding.
Abstract: South Africa is in its post-industrial era moving from
the primary and secondary sector to the tertiary sector. The study
investigated the impact of the disaggregated energy consumption
(coal, oil, and electricity) on the primary, secondary and tertiary
sectors of the economy between 1980 and 2012 in South Africa.
Using vector error correction model, it was established that South
Africa is an energy dependent economy, and that energy (especially
electricity and oil) is a limiting factor of growth. This implies that
implementation of energy conservation policies may hamper
economic growth. Output growth is significantly outpacing energy
supply, which has necessitated load shedding. To meet up the excess
energy demand, there is a need to increase the generating capacity
which will necessitate increased investment in the electricity sector as
well as strategic steps to increase oil production. There is also need to
explore more renewable energy sources, in order to meet the growing
energy demand without compromising growth and environmental
sustainability. Policy makers should also pursue energy efficiency
policies especially at sectoral level of the economy.
Abstract: The aim of this study is to empirically investigate the
mediating impact of export performance (EP) between technological
advancement capabilities and business performance (BP) of
Malaysian manufacturing micro, small and medium sized enterprises
(MSME’s). Firm’s technological advancement resources are
hypothesized as a platform to enhance both exports and BP of
manufacturing MSMEs in Malaysia. This study is twofold, primary it
has investigated that technological advancement capabilities helps to
appreciates main performance measures noted in terms of EP and
Secondly, it investigates that how efficiently and effectively
technological advancement capabilities can contribute in overall
Malaysian MSME’s BP. Smart PLS-3 statistical software is used to
know the association between technological advancement
capabilities, MSME’s EP and BP. In this study, the data was
composed from Malaysian manufacturing MSME’s in east coast
industrial zones known as the manufacturing hub of MSMEs. Seven
hundred and fifty (750) questionnaires were distributed, but only 148
usable questionnaires are returned. The finding of this study indicated
that technological advancement capabilities helps to strengthen the
export in term of time and cost efficient and it plays a significant role
in appreciating their BP. This study is helpful for small and medium
enterprise owners who intend to expand their business overseas and
though smart technological advancement resources they can achieve
their business competitiveness and excellence both at local and
international markets.
Abstract: Hydraulic fracturing is one of the most important
stimulation techniques available to the petroleum engineer to extract
hydrocarbons in tight gas sandstones. It allows more oil and gas
production in tight reservoirs as compared to conventional means.
The main aim of the study is to optimize the hydraulic fracturing as
technique and for this purpose three multi-zones layer formation is
considered and fractured contemporaneously. The three zones are
named as Zone1 (upper zone), Zone2 (middle zone) and Zone3
(lower zone) respectively and they all occur in shale rock. Simulation was performed with Mfrac integrated software which
gives a variety of 3D fracture options. This simulation process
yielded an average fracture efficiency of 93.8%for the three
respective zones and an increase of the average permeability of the
rock system. An average fracture length of 909 ft with net height
(propped height) of 210 ft (average) was achieved. Optimum
fracturing results was also achieved with maximum fracture width of
0.379 inches at an injection rate of 13.01 bpm with 17995 Mscf of
gas production.
Abstract: Obturator Foramen is a specific structure in Pelvic
bone images and recognition of it is a new concept in medical image
processing. Moreover, segmentation of bone structures such as
Obturator Foramen plays an essential role for clinical research in
orthopedics. In this paper, we present a novel method to analyze the
similarity between the substructures of the imaged region and a hand
drawn template as a preprocessing step for computation of Pelvic
bone rotation on hip radiographs. This method consists of integrated
usage of Marker-controlled Watershed segmentation and Zernike
moment feature descriptor and it is used to detect Obturator Foramen
accurately. Marker-controlled Watershed segmentation is applied to
separate Obturator Foramen from the background effectively. Then,
Zernike moment feature descriptor is used to provide matching
between binary template image and the segmented binary image for
final extraction of Obturator Foramens. Finally, Pelvic bone rotation
rate calculation for each hip radiograph is performed automatically to
select and eliminate hip radiographs for further studies which depend
on Pelvic bone angle measurements. The proposed method is tested
on randomly selected 100 hip radiographs. The experimental results
demonstrated that the proposed method is able to segment Obturator
Foramen with 96% accuracy.
Abstract: Presently various computational techniques are used
in modeling and analyzing environmental engineering data. In the
present study, an intra-comparison of polynomial and radial basis
kernel functions based on Support Vector Regression and, in turn, an
inter-comparison with Multi Linear Regression has been attempted in
modeling mass transfer capacity of vertical (θ = 90O) and inclined (θ
multiple plunging jets (varying from 1 to 16 numbers). The data set
used in this study consists of four input parameters with a total of
eighty eight cases, forty four each for vertical and inclined multiple
plunging jets. For testing, tenfold cross validation was used.
Correlation coefficient values of 0.971 and 0.981 along with
corresponding root mean square error values of 0.0025 and 0.0020
were achieved by using polynomial and radial basis kernel functions
based Support Vector Regression respectively. An intra-comparison
suggests improved performance by radial basis function in
comparison to polynomial kernel based Support Vector Regression.
Further, an inter-comparison with Multi Linear Regression
(correlation coefficient = 0.973 and root mean square error = 0.0024)
reveals that radial basis kernel functions based Support Vector
Regression performs better in modeling and estimating mass transfer
by multiple plunging jets.
Abstract: An early diagnosis of bone metastasis is very
important for making a right decision on a subsequent therapy. One
of the most important steps to be taken initially, for developing a new
radiopharmaceutical is the measurement of organ radiation exposure
dose. In this study, the dosimetric studies of a novel agent for
SPECT-imaging of the bone metastasis, 111In-(4-
{[(bis(phosphonomethyl))carbamoyl]methyl}7,10bis(carboxymethyl)
-1,4,7,10-tetraazacyclododec-1-yl) acetic acid (111In-BPAMD)
complex, have been carried out to estimate the dose in human organs
based on the data derived from mice. The radiolabeled complex was
prepared with high radiochemical purity in the optimal conditions.
Biodistribution studies of the complex was investigated in the male
Syrian mice at the selected times after injection (2, 4, 24 and 48 h).
The human absorbed dose estimation of the complex was made based
on data derived from the mice by the radiation absorbed dose
assessment resource (RADAR) method. 111In-BPAMD complex was prepared with high radiochemical
purity >95% (ITLC) and specific activities of 2.85 TBq/mmol. Total
body effective absorbed dose for 111In-BPAMD was 0.205
mSv/MBq. This value is comparable to the other 111In clinically used
complexes. The results show that the dose with respect to the critical
organs is satisfactory within the acceptable range for diagnostic
nuclear medicine procedures. Generally, 111In-BPAMD has
interesting characteristics and it can be considered as a viable agent
for SPECT-imaging of the bone metastasis in the near future.
Abstract: A clay soil classified as A-7-6 and CH soil according
to AASHTO and unified soil classification system respectively, was
stabilized using A-3 soil (AASHTO soil classification system). The
clay soil was replaced with 0%, 10%, 20%, to 100% A-3 soil,
compacted at both British Standard Light (BSL) and British Standard
Heavy (BSH) compaction energy levels and using Unconfined
Compressive Strength (UCS) as evaluation criteria. The Maximum
Dry Density (MDD) of the treated soils at both the BSL and BSH
compaction energy levels showed increase from 0% to 40% A-3 soil
replacement after which the values reduced to 100% replacement.
The trend of the Optimum Moisture Content (OMC) with varied A-3
soil replacement was similar to that of MDD but in a reversed order.
The OMC reduced from 0% to 40% A-3 soil replacement after which
the values increased to 100% replacement. This trend was attributed
to the observed reduction in void ratio from 0% to 40% replacement
after which the void ratio increased to 100% replacement. The
maximum UCS for the soil at varied A-3 soil replacement increased
from 272 and 770 kN/m2 for BSL and BSH compaction energy level
at 0% replacement to 295 and 795 kN/m2 for BSL and BSH
compaction energy level respectively at 10% replacement after which
the values reduced to 22 and 60 kN/m2 for BSL and BSH compaction
energy level respectively at 70% replacement. Beyond 70%
replacement, the mixtures could not be moulded for UCS test.