Abstract: A photopolymerizable dimethacrylamide was synthesized and copolymerized with the selected (meth)acrylates. The polymerization rate, degree of conversion, gel time, and compressive strength of the formed neat resins were investigated. The results show that in situ photo-polymerization of the synthesized dimethacrylamide with comonomers having an electron-withdrawing and/or acrylate group dramatically increased the polymerization rate, degree of conversion, and compressive strength. On the other hand, an electron-donating group on either carbon-carbon double bond or the ester linkage slowed down the polymerization. In contrast, the triethylene glycol dimethacrylate-based system did not show a clear pattern. Both strong hydrogen-bonding between (meth)acrylamide and organic acid groups may be responsible for higher compressive strengths. Within the limitation of this study, the photo-polymerization of dimethacrylamide can be greatly accelerated by copolymerization with monomers having electron-withdrawing and/or acrylate groups. The monomers with methacrylate group can significantly reduce the polymerization rate and degree of conversion.
Abstract: The objective of this study was to synthesize and characterize 5-acryloyloxy-3,4-dichlorocrotonolactone (a furanone derivative), use this derivative to modify a dental restorative, and study the effect of the derivative on the antibacterial activity and compressive strength of the formed restorative. In this study, a furanone derivative was synthesized, characterized, and used to formulate a dental restorative. Compressive strength (CS) and S. mutans viability were used to evaluate the mechanical strength and antibacterial activity of the formed restorative. The fabricated restorative specimens were photocured and conditioned in distilled water at 37oC for 24 h, followed by direct testing for CS or/and incubating with S. mutans for 48 h for antibacterial testing. The results show that the modified dental restorative showed a significant antibacterial activity without substantially decreasing the mechanical strengths. With addition of the antibacterial derivative up to 30%, the restorative kept its original CS nearly unchanged but showed a significant antibacterial activity with 68% reduction in the S. mutans viability. Furthermore, the antibacterial function of the modified restorative was not affected by human saliva. The aging study also indicates that the modified restorative may have a long-lasting antibacterial function. It is concluded that this experimental antibacterial restorative may potentially be developed into a clinically attractive dental filling restorative due to its high mechanical strength and antibacterial function.
Abstract: The objective of this study was to synthesize and
characterize the poly(alkenoic acid)s with different molecular
structures, use these polymers to formulate a dental cement
restorative, and study the effect of molecular structures on reaction
kinetics, viscosity, and mechanical strengths of the formed polymers
and cement restoratives. In this study, poly(alkenoic acid)s with
different molecular structures were synthesized. The purified
polymers were formulated with commercial Fuji II LC glass fillers to
form the experimental cement restoratives. The reaction kinetics was
studied via 1HNMR spectroscopy. The formed restoratives were
evaluated using compressive strength, diametral tensile strength,
flexural strength, hardness and wear-resistance tests. Specimens were
conditioned in distilled water at 37oC for 24 h prior to testing. Fuji II
LC restorative was used as control. The results show that the higher
the arm number and initiator concentration, the faster the reaction
was. It was also found that the higher the arm number and branching
that the polymer had, the lower the viscosity of the polymer in water
and the lower the mechanical strengths of the formed restorative. The
experimental restoratives were 31-53% in compressive strength, 37-
55% in compressive modulus, 80-126% in diametral tensile strength,
76-94% in flexural strength, 4-21% in fracture toughness and 53-96%
in hardness higher than Fuji II LC. For wear test, the experimental
restoratives were only 5.4-13% of abrasive and 6.4-12% of attritional
wear depths of Fuji II LC in each wear cycle. The aging study also
showed that all the experimental restoratives increased their strength
continuously during 30 days, unlike Fuji II LC. It is concluded that
polymer molecular structures have significant and positive impact on
mechanical properties of dental cement restoratives.