Abstract: An adaptive dynamic cerebellar model articulation
controller (DCMAC) neural network used for solving the prediction
and identification problem is proposed in this paper. The proposed
DCMAC has superior capability to the conventional cerebellar model
articulation controller (CMAC) neural network in efficient learning
mechanism, guaranteed system stability and dynamic response. The
recurrent network is embedded in the DCMAC by adding feedback
connections in the association memory space so that the DCMAC
captures the dynamic response, where the feedback units act as
memory elements. The dynamic gradient descent method is adopted to
adjust DCMAC parameters on-line. Moreover, the analytical method
based on a Lyapunov function is proposed to determine the
learning-rates of DCMAC so that the variable optimal learning-rates
are derived to achieve most rapid convergence of identifying error.
Finally, the adaptive DCMAC is applied in two computer simulations.
Simulation results show that accurate identifying response and
superior dynamic performance can be obtained because of the
powerful on-line learning capability of the proposed DCMAC.
Abstract: Synchronous cooperative systems (SCS) bring together users that are geographically distributed and connected through a network to carry out a task. Examples of SCS include Tele- Immersion and Tele-Conferences. In SCS, the coordination is the core of the system, and it has been defined as the act of managing interdependencies between activities performed to achieve a goal. Some of the main problems that SCS present deal with the management of constraints between simultaneous activities and the execution ordering of these activities. In order to resolve these problems, orderings based on Lamport-s happened-before relation have been used, namely, causal, Δ-causal, and causal-total orderings. They mainly differ in the degree of asynchronous execution allowed. One of the most important orderings is the causal order, which establishes that the events must be seen in the cause-effect order as they occur in the system. In this paper we show that for certain SCS (e.g. videoconferences, tele-immersion) where some degradation of the system is allowed, ensuring the causal order is still rigid, which can render negative affects to the system. In this paper, we illustrate how a more relaxed ordering, which we call Fuzzy Causal Order (FCO), is useful for such kind of systems by allowing a more asynchronous execution than the causal order. The benefit of the FCO is illustrated by applying it to a particular scenario of intermedia synchronization of an audio-conference system.
Abstract: Mammalian genomes contain large number of
retroelements (SINEs, LINEs and LTRs) which could affect
expression of protein coding genes through associated transcription
factor binding sites (TFBS). Activity of the retroelement-associated
TFBS in many genes is confirmed experimentally but their global
functional impact remains unclear. Human SINEs (Alu repeats) and
mouse SINEs (B1 and B2 repeats) are known to be clustered in GCrich
gene rich genome segments consistent with the view that they
can contribute to regulation of gene expression. We have shown
earlier that Alu are involved in formation of cis-regulatory modules
(clusters of TFBS) in human promoters, and other authors reported
that Alu located near promoter CpG islands have an increased
frequency of CpG dinucleotides suggesting that these Alu are
undermethylated. Human Alu and mouse B1/B2 elements have an
internal bipartite promoter for RNA polymerase III containing
conserved sequence motif called B-box which can bind basal
transcription complex TFIIIC. It has been recently shown that TFIIIC
binding to B-box leads to formation of a boundary which limits
spread of repressive chromatin modifications in S. pombe. SINEassociated
B-boxes may have similar function but conservation of
TFIIIC binding sites in SINEs located near mammalian promoters
has not been studied earlier. Here we analysed abundance and
distribution of retroelements (SINEs, LINEs and LTRs) in annotated
sequences of the Database of mammalian transcription start sites
(DBTSS). Fractions of SINEs in human and mouse promoters are
slightly lower than in all genome but >40% of human and mouse
promoters contain Alu or B1/B2 elements within -1000 to +200 bp
interval relative to transcription start site (TSS). Most of these SINEs
is associated with distal segments of promoters (-1000 to -200 bp
relative to TSS) indicating that their insertion at distances >200 bp
upstream of TSS is tolerated during evolution. Distribution of SINEs
in promoters correlates negatively with the distribution of CpG
sequences. Using analysis of abundance of 12-mer motifs from the
B1 and Alu consensus sequences in genome and DBTSS it has been
confirmed that some subsegments of Alu and B1 elements are poorly
conserved which depends in part on the presence of CpG
dinucleotides. One of these CpG-containing subsegments in B1
elements overlaps with SINE-associated B-box and it shows better
conservation in DBTSS compared to genomic sequences. It has been
also studied conservation in DBTSS and genome of the B-box
containing segments of old (AluJ, AluS) and young (AluY) Alu
repeats and found that CpG sequence of the B-box of old Alu is
better conserved in DBTSS than in genome. This indicates that Bbox-
associated CpGs in promoters are better protected from
methylation and mutation than B-box-associated CpGs in genomic
SINEs. These results are consistent with the view that potential
TFIIIC binding motifs in SINEs associated with human and mouse
promoters may be functionally important. These motifs may protect
promoters from repressive histone modifications which spread from
adjacent sequences. This can potentially explain well known
clustering of SINEs in GC-rich gene rich genome compartments and
existence of unmethylated CpG islands.
Abstract: In this paper we consider a nonlinear feedback control called augmented automatic choosing control (AACC) for nonlinear systems with constrained input. Constant terms which arise from section wise linearization of a given nonlinear system are treated as coefficients of a stable zero dynamics.Parameters included in the control are suboptimally selectedby extremizing a combination of Hamiltonian and Lyapunov functions with the aid of the genetic algorithm. This approach is applied to a field excitation control problem of power system to demonstrate the splendidness of the AACC. Simulation results show that the new controller can improve performance remarkably well.
Abstract: Objective of this study was to study and compare the effectiveness of inspectors who had different workloads for feed forward and feedback training. The visual search task was simulated to search for specified alphabets called defects. These defects were included of four alphabets in Thai and English such as s ภ, ถ, X, and V with different background. These defects were combined in the specified alphabets and were given the different three backgrounds i.e., Thai, English, and mixed English and Thai alphabets. Sixty students were chosen as a sample in this study and test for final selection subject. Finally, five subjects were taken into testing process. They were asked to search for defects after they were provided basic information. Experiment design was used factorial design and subjects were trained for feed forward and the feedback training. The results show that both trainings were affected on mean search time. It was also found that the feedback training can increase the effectiveness of visual inspectors rather than the feed forward training significantly different at the level of .05
Abstract: The paper presents an on-line recognition machine
(RM) for continuous/isolated, dynamic and static gestures that arise
in Flight Deck Officer (FDO) training. RM is based on generic pattern
recognition framework. Gestures are represented as templates using
summary statistics. The proposed recognition algorithm exploits temporal
and spatial characteristics of gestures via dynamic programming
and Markovian process. The algorithm predicts corresponding index
of incremental input data in the templates in an on-line mode.
Accumulated consistency in the sequence of prediction provides a
similarity measurement (Score) between input data and the templates.
The algorithm provides an intuitive mechanism for automatic detection
of start/end frames of continuous gestures. In the present paper,
we consider isolated gestures. The performance of RM is evaluated
using four datasets - artificial (W TTest), hand motion (Yang) and
FDO (tracker, vision-based ). RM achieves comparable results which
are in agreement with other on-line and off-line algorithms such as
hidden Markov model (HMM) and dynamic time warping (DTW).
The proposed algorithm has the additional advantage of providing
timely feedback for training purposes.
Abstract: This paper describes identification of the two poles
unstable SOPDT process, especially with large time delay. A new
modified relay feedback identification method for two poles unstable
SOPDT process is proposed. Furthermore, for the two poles unstable
SOPDT process, an additional Derivative controller is incorporated
parallel with relay to relax the constraint on the ratio of delay to the
unstable time constant, so that the exact model parameters of
unstable processes can be identified. To cope with measurement
noise in practice, a low pass filter is suggested to get denoised output
signal toimprove the exactness of model parameter of unstable
process. PID Lead-lag tuning formulas are derived for two poles
unstable (SOPDT) processes based on IMC principle. Simulation
example illustrates the effectiveness and the simplicity of the
proposed identification and control method.
Abstract: The aim of this paper is to present a new
three-dimensional proportional-pursuit coupled (PP) guidance law to
track highly maneuverable aircraft. Utilizing a 3-D polar coordinate frame, the PP guidance law is formed by collecting proportional
navigation guidance in Z-R plane and pursuit guidance in X-Y plane.
Feedback linearization control method to solve the guidance
accelerations is used to implement PP guidance. In order to
compensate the actuator time delay, the time delay compensated
version of PP guidance law (CPP) was derived and proved the
effectiveness of modifying the problem of high acceleration in the final
phase of pursuit guidance and improving the weak robustness of
proportional navigation. The simulation results for intercepting Max G
turn situation show that the proposed proportional-pursuit coupled
guidance law guidance law with actuator delay compensation (CPP)
possesses satisfactory robustness and performance.
Abstract: Current advancements in nanotechnology are dependent
on the capabilities that can enable nano-scientists to extend their eyes
and hands into the nano-world. For this purpose, a haptics (devices
capable of recreating tactile or force sensations) based system for
AFM (Atomic Force Microscope) is proposed. The system enables
the nano-scientists to touch and feel the sample surfaces, viewed
through AFM, in order to provide them with better understanding of
the physical properties of the surface, such as roughness, stiffness and
shape of molecular architecture. At this stage, the proposed work uses
of ine images produced using AFM and perform image analysis to
create virtual surfaces suitable for haptics force analysis. The research
work is in the process of extension from of ine to online process
where interaction will be done directly on the material surface for
realistic analysis.
Abstract: Power line channel is proposed as an alternative for broadband data transmission especially in developing countries like Tanzania [1]. However the channel is affected by stochastic attenuation and deep notches which can lead to the limitation of channel capacity and achievable data rate. Various studies have characterized the channel without giving exactly the maximum performance and limitation in data transfer rate may be this is due to complexity of channel modeling being used. In this paper the channel performance of medium voltage, low voltage and indoor power line channel is presented. In the investigations orthogonal frequency division multiplexing (OFDM) with phase shift keying (PSK) as carrier modulation schemes is considered, for indoor, medium and low voltage channels with typical ten branches and also Golay coding is applied for medium voltage channel. From channels, frequency response deep notches are observed in various frequencies which can lead to reduce the achievable data rate. However, is observed that data rate up to 240Mbps is realized for a signal to noise ratio of about 50dB for indoor and low voltage channels, however for medium voltage a typical link with ten branches is affected by strong multipath and coding is required for feasible broadband data transfer.
Abstract: Proton transfer and hydrogen bonding are two aspects
of the chemistry of hydrogen that respectively govern the behaviour
and structure of many molecules, both simple and complex. All the
theoretical enol and keto conformations of 1,3-diphenyl-1,3-
propandion known as dibenzoylmethane (DBM), have been
investigated by means of atoms in molecules (AIM) theory. It was
found that the most stable conformers are those stabilized by
hydrogen bridges.The aim of the present paper is a thorough
conformational analysis of DBM (with special attention on chelated
cis-enol conformers) in order to obtain detailed information on the
geometrical parameters, relative stabilities and rotational motion of
the phenyl groups. It is also important to estimate the barrier height
for ptoton transfer and hydrogen bond strength, which are the main
factors governing conformational stability.
Abstract: A high-linearity and high-speed current-mode sampleand-
hold circuit is designed and simulated using a 0.25μm CMOS
technology. This circuit design is based on low voltage and it utilizes
a fully differential circuit. Due to the use of only two switches the
switch related noise has been reduced. Signal - dependent -error is
completely eliminated by a new zero voltage switching technique.
The circuit has a linearity error equal to ±0.05μa, i.e. 12-bit
accuracy with a ±160 μa differential output - input signal frequency
of 5MHZ, and sampling frequency of 100 MHZ. Third
harmonic is equal to –78dB.
Abstract: In general, reports are a form of representing data in
such way that user gets the information he needs. They can be built in
various ways, from the simplest (“select from") to the most complex
ones (results derived from different sources/tables with complex
formulas applied). Furthermore, rules of calculations could be written
as a program hard code or built in the database to be used by dynamic
code. This paper will introduce two types of reports, defined in the
DB structure. The main goal is to manage calculations in optimal
way, keeping maintenance of reports as simple and smooth as
possible.
Abstract: In this paper, a new design technique for enhancing
bandwidth that improves the performance of a conventional
microstrip patch antenna is proposed. This paper presents a novel
wideband probe fed inverted slotted microstrip patch antenna. The
design adopts contemporary techniques; coaxial probe feeding,
inverted patch structure and slotted patch. The composite effect of
integrating these techniques and by introducing the proposed patch,
offer a low profile, broadband, high gain, and low cross-polarization
level. The results for the VSWR, gain and co-and cross-polarization
patterns are presented. The antenna operating the band of 1.80-2.36
GHz shows an impedance bandwidth (2:1 VSWR) of 27% and a gain
of 10.18 dBi with a gain variation of 1.12 dBi. Good radiation
characteristics, including a cross-polarization level in xz-plane less
than -42 dB, have been obtained.
Abstract: An exploration in the competency of the optical
multilevel Mapping Multiplexing Technique (MMT) system in
tolerating to the impact of nonlinearities as Self Phase Modulation
(SPM) during the presence of dispersion compensation methods. The
existence of high energy pulses stimulates deterioration in the chirp
compression process attained by SPM which introduces an upper
power boundary limit. An evaluation of the post and asymmetric prepost
fiber compensation methods have been deployed on the MMT
system compared with others of the same bit rate modulation formats.
The MMT 40 Gb/s post compensation system has 1.4 dB
enhancements to the 40 Gb/s 4-Arysystem and less than 3.9 dB
penalty compared to the 40 Gb/s OOK-RZsystem. However, the
optimized Pre-Post asymmetric compensation has an enhancement of
4.6 dB compared to the Post compensation MMT configuration for a
30% pre compensation dispersion.
Abstract: PROFIBUS (PROcess FIeld BUS) which is defined with international standarts (IEC61158, EN50170) is the most popular fieldbus, and provides a communication between industrial applications which are located in different control environment and location in manufacturing, process and building automation. Its communication speed is from 9.6 Kbps to 12 Mbps over distances from 100 to 1200 meters, and so it is to be often necessary to interconnect them in order to break these limits. Unfortunately this interconnection raises several issues and the solutions found so far are not very satisfactory. In this paper, we propose a new solution to interconnect PROFIBUS segments, which uses a wireless MAN based on the IEEE 802.16 standard as a backbone system. Also, the solution which is described a model for internetworking unit integrates the traffic generated by PROFIBUS segments into IEEE 802.16 wireless MAN using encapsulation technique.
Abstract: The pseudorandom number generators based on linear
feedback shift registers (LFSRs), are very quick, easy and secure in
the implementation of hardware and software. Thus they are very
popular and widely used. But LFSRs lead to fairly easy
cryptanalysis due to their completely linearity properties. In this
paper, we propose a stochastic generator, which is called Random
Feedback Shift Register (RFSR), using stochastic transformation
(Random block) with one-way and non-linearity properties.
Abstract: The error monitoring and processing system, EMPS is
the system located in the substantia nigra of the midbrain, basal
ganglia and cortex of the forebrain, and plays a leading role in error
detection and correction. The main components of EMPS are the
dopaminergic system and anterior cingulate cortex. Although, recent
studies show that alcohol disrupts the EMPS, the ways in which
alcohol affects this system are poorly understood. Based on current
literature data, here we suggest a hypothesis of alcohol-related
glucose-dependent system of error monitoring and processing, which
holds that the disruption of the EMPS is related to the competency of
glucose homeostasis regulation, which in turn may determine the
dopamine level as a major component of EMPS. Alcohol may
indirectly disrupt the EMPS by affecting dopamine level through
disorders in blood glucose homeostasis regulation.
Abstract: This paper presents the design and layout of a two stage, high speed operational amplifiers using standard 0.35um CMOS technology. The design procedure involves designing the bias circuit, the differential input pair, and the gain stage using CAD tools. Both schematic and layout of the operational amplifier along with the comparison in the results of the two has been presented. The operational amplifier designed, has a gain of 93.51db at low frequencies. It has a gain bandwidth product of 55.07MHz, phase margin of 51.9º and a slew rate of 22v/us for a load of capacitor of 10pF.
Abstract: Severe acute respiratory syndrome (SARS) is a respiratory disease in humans which is caused by the SARS coronavirus. The treatment of coronavirus-associated SARS has been evolving and so far there is no consensus on an optimal regimen. The mainstream therapeutic interventions for SARS involve broad-spectrum antibiotics and supportive care, as well as antiviral agents and immunomodulatory therapy. The Protein- Ligand interaction plays a significant role in structural based drug designing. In the present work we have taken the receptor Angiotensin converting enzyme 2 and identified the drugs that are commonly used against SARS. They are Lopinavir, Ritonavir, Ribavirin, and Oseltamivir. The receptor Angiotensin converting enzyme 2 (ACE-2) was docked with above said drugs and the energy value obtained are as follows, Lopinavir (-292.3), Ritonavir (-325.6), Oseltamivir (- 229.1), Ribavirin (-208.8). Depending on the least energy value we have chosen the best two drugs out of the four conventional drugs. We tried to improve the binding efficiency and steric compatibility of the two drugs namely Ritonavir and Lopinavir. Several modifications were made to the probable functional groups (phenylic, ketonic groups in case of Ritonavir and carboxylic groups in case of Lopinavir respectively) which were interacting with the receptor molecule. Analogs were prepared by Marvin Sketch software and were docked using HEX docking software. Lopinavir analog 8 and Ritonavir analog 11 were detected with significant energy values and are probable lead molecule. It infers that some of the modified drugs are better than the original drugs. Further work can be carried out to improve the steric compatibility of the drug based upon the work done above for a more energy efficient binding of the drugs to the receptor.