Abstract: In review the generalized data about biological
activity of anthraquinone-containing plants and specimens on their
basis is presented. Data of traditional medicine, results of
bioscreening and clinical researches of specimens are analyzed.
Abstract: Within the framework of this research, the regulatory
documents, which are in force in relation to this industry, were
analyzed. The main attention is turned to their modernization and
necessity of their compliance with European standards.
It is a current issue to direct the efforts of state policy on support
of business by implementing infrastructural projects, as well as by
development of human resources, which may be possible by
supporting the relevant higher and vocational studying-educational
programs.
Abstract: Peace education supports a holistic appreciation for
the value of life and the interdependence of all living systems. Peace
education aims to build a culture of peace. One way of building a
culture of peace is through environmental stewardship. This study
sought to find out the environmental stewardship practices in selected
Higher Education Institutions (HEIs) in the Philippines and how
these environmental stewardship practices lead to building a culture
of peace. The findings revealed that there is still room for
improvement in implementing environmental stewardship in schools
through academic service learning. In addition, the following
manifestations are implemented very satisfactorily in schools: 1)
waste reduction, reuse, and recycling, 2) community service, and 3)
clean and green surroundings. Administrators of schools in the study
lead their staff and students in implementing environmental
stewardship. It could be concluded that those involved in
environmental stewardship display an acceptable culture of peace,
particularly solidarity, respect for persons, and inner peace.
Abstract: Information technology and information systems are
currently at a tipping point. The digital age fundamentally transforms
a large number of industries in the ways they work. Lines between
business and technology blur. Researchers have acknowledged that
this is the time in which the IT/IS organisation needs to re-strategize
itself. In this paper, the author provides a structured review of the IS
and organisation design literature addressing the question of how the
digital age changes the design categories of an IT/IS organisation
design. The findings show that most papers just analyse single
aspects of either IT/IS relevant information or generic organisation
design elements but miss a holistic ‘big-picture’ onto an IT/IS
organisation design. This paper creates a holistic IT/IS organisation
design framework bringing together the IS research strand, the digital
strand and the generic organisation design strand. The research
identified four IT/IS organisation design categories (strategy,
structure, processes and people) and discusses the importance of two
additional categories (sourcing and governance). The authors findings
point to a first anchor point from which further research needs to be
conducted to develop a holistic IT/IS organisation design framework.
Abstract: If teamwork is the key to organizational learning,
productivity and growth, then, why do some teams succeed in
achieving these, while others falter at different stages? Building
teams in higher education institutions has been a challenge and an
open-ended constructivist approach was considered on an
experimental basis for this study to address this challenge. For this
research, teams of students from the MBA program were chosen to
study the effect of teamwork in learning, the motivation levels among
student team members, and the effect of collaboration in achieving
team goals. The teams were built on shared vision and goals,
cohesion was ensured, positive induction in the form of faculty
mentoring was provided for each participating team and the results
have been presented with conclusions and suggestions.
Abstract: The key role in phenomenological modelling of cyclic
plasticity is good understanding of stress-strain behaviour of given
material. There are many models describing behaviour of materials
using numerous parameters and constants. Combination of individual
parameters in those material models significantly determines whether
observed and predicted results are in compliance. Parameter
identification techniques such as random gradient, genetic algorithm
and sensitivity analysis are used for identification of parameters using
numerical modelling and simulation. In this paper genetic algorithm
and sensitivity analysis are used to study effect of 4 parameters of
modified AbdelKarim-Ohno cyclic plasticity model. Results
predicted by Finite Element (FE) simulation are compared with
experimental data from biaxial ratcheting test with semi-elliptical
loading path.
Abstract: This paper reports the numerical simulation of doublediffusive
natural convection flows within a horizontal annular filled
with a saturated porous medium. The analysis concerns the influence
of the different parameters governing the problem, namely, the
Rayleigh number Ra, the Lewis number Le and the buoyancy ratio N,
on the heat and mass transfer and on the flow structure, in the case of
a fixed radius ratio R = 2. The numerical model used for the
discretization of the dimensionless equations governing the problem
is based on the finite difference method, using the ADI scheme. The
study is focused on steady-state solutions in the cooperation situation.
Abstract: In Jordan having deficit atmospheric precipitation, an
increase in water demand occurs during summer months. Jordan can
be regarded with a relatively high potential for wastewater recycling
and reuse. The main purpose of this paper was to investigate the
removal of total suspended solids (TSS) and chemical oxygen
demand (COD) for olive mill wastewater (OMW) by
electrocoagulation (EC) process. In the combination of
electrocoagulation by using coupled iron–aluminum electrodes, the
optimum working pH was found to be around 6. Results indicated
that the electrocoagulation process allowed removal of TSS and COD
of about 82.5% and 47.5%, respectively at 45 mA/cm2 after 70
minutes by using coupled iron–aluminum electrodes. It was
demonstrated that the maximum TSS and COD removals were
obtained at some optimum experimental parameters for current
density, pH, and reaction time.
Abstract: The effects of hypertension are often lethal thus its
early detection and prevention is very important for everybody. In
this paper, a neural network (NN) model was developed and trained
based on a dataset of hypertension causative parameters in order to
forecast the likelihood of occurrence of hypertension in patients. Our
research goal was to analyze the potential of the presented NN to
predict, for a period of time, the risk of hypertension or the risk of
developing this disease for patients that are or not currently
hypertensive. The results of the analysis for a given patient can
support doctors in taking pro-active measures for averting the
occurrence of hypertension such as recommendations regarding the
patient behavior in order to lower his hypertension risk. Moreover,
the paper envisages a set of three example scenarios in order to
determine the age when the patient becomes hypertensive, i.e.
determine the threshold for hypertensive age, to analyze what
happens if the threshold hypertensive age is set to a certain age and
the weight of the patient if being varied, and, to set the ideal weight
for the patient and analyze what happens with the threshold of
hypertensive age.
Abstract: There is a trend in development discourse to
understand and explain the level of corruption in Nigeria, its anticorruption
crusade and why it is failing, as well as its level of
compliance with International standards of United Nations
Convention against Corruption (UNCAC) & African Union
Convention on Converting and Preventing Corruption) to which
Nigeria is a signatory. This paper discusses the legal and
Constitutional provisions relating to corrupt practices and safeguards
in Nigeria, as well as the obstacles to the implementation of these
Conventions.
The paper highlights the challenges posed to the Anti-Corruption
crusade by analysing the loopholes that exist both in administrative
structure and in scope of the relevant laws. The paper argues that
Nigerian Constitution did not make adequate provisions for the
implementation of the conventions, hence a proposal which will
ensure adequate provision for implementing the conventions to better
the lives of Nigerians. The paper concludes that there is the need to
build institutional parameters, adequate constitutional and structural
safeguards, as well as to synergise strategies, collaborations and
alliances to facilitate the timely domestication and implementation of
the conventions.
Abstract: Interaction of Schiff base complexes of Iron and
Manganese: Iron [N, N’ Bis (5- (triphenyl phosphonium methyl)
salicylidene) -1, 2 ethanediamine) chloride, [Fe Salen]Cl; Manganese
[N, N’ Bis (5- (triphenyl phosphonium methyl) salicylidene) -1, 2
ethanediamine) acetate, were investigated by spectroscopic and
isothermal titration calorimetry techniques (ITC).
The absorbance spectra of complexes have shown hyper and
hypochromism in the presence of DNA that is indication of
interaction of complexes with DNA. The linear dichroism (LD)
measurements confirmed the bending of DNA in the presence of
complexes.
Furthermore, Isothermal titration calorimetry experiments
approved that complexes bound to DNA on the base of both
electrostatic and hydrophobic interactions. More, ITC profile exhibits
the existence of two binding phases for the complexes. Antibacterial
activity of ligand and complexes were tested in vitro to evaluate their
activity against the gram positive and negative bacteria.
Abstract: The Algeria by its location offers a rich and diverse
vegetation. A large number of aromatic and medicinal plants grow
spontaneously. The interest in these plants has continued to grow in
recent years. Their particular properties due to the essential oil
fraction can be utilized to treat microbial infections. To this end, and
in the context of the valuation of the Algerian flora, we became
interested in the species of the family Lamiaceae which is one of the
most used as a global source of spices. The plant on which we have
based our choice is a species of sage "Salvia officinalis" from the
Isser localized region within the province of Boumerdes. This work
focuses on the study of the antimicrobial activity of essential oil
extracted from the leaves of Salvia officinalis. The extraction is
carried out by essential oil hydrodistillation and reveals a yield of
1.06℅. The study of the antimicrobial activity of the essential oil by
the method of at aromatogramme shown that Gram positive bacteria
are most susceptible (Staphylococcus aureus and Bacillus subtilis)
with a strong inhibition of growth. The yeast Candida albicans
fungus Aspergillus niger and have shown moderately sensitive.
Abstract: Two finite element (FEM) models are presented in
this paper to address the random nature of the response of glued
timber structures made of wood segments with variable elastic
moduli evaluated from 3600 indentation measurements. This total
database served to create the same number of ensembles as was the
number of segments in the tested beam. Statistics of these ensembles
were then assigned to given segments of beams and the Latin
Hypercube Sampling (LHS) method was called to perform 100
simulations resulting into the ensemble of 100 deflections subjected
to statistical evaluation. Here, a detailed geometrical arrangement of
individual segments in the laminated beam was considered in the
construction of two-dimensional FEM model subjected to in fourpoint
bending to comply with the laboratory tests. Since laboratory
measurements of local elastic moduli may in general suffer from a
significant experimental error, it appears advantageous to exploit the
full scale measurements of timber beams, i.e. deflections, to improve
their prior distributions with the help of the Bayesian statistical
method. This, however, requires an efficient computational model
when simulating the laboratory tests numerically. To this end, a
simplified model based on Mindlin’s beam theory was established.
The improved posterior distributions show that the most significant
change of the Young’s modulus distribution takes place in laminae in
the most strained zones, i.e. in the top and bottom layers within the
beam center region. Posterior distributions of moduli of elasticity
were subsequently utilized in the 2D FEM model and compared with
the original simulations.
Abstract: An experimental study was performed to investigate
the behavior and strength of proposed technique to connect
reinforced concrete (RC) beam to steel or composite columns. This
approach can practically be used in several types of building
construction. In this technique, the main beam of the frame consists
of a transfer part (part of beam; Tr.P) and a common reinforcement
concrete beam. The transfer part of the beam is connected to the
column, whereas the rest of the beam is connected to the transfer part
from each side. Four full-scale beam-column connections were tested
under static loading. The test parameters were the length of the
transfer part and the column properties. The test results show that
using of the transfer part technique leads to modify the deformation
capabilities for the RC beam and hence it increases its resistance
against failure. Increase in length of the transfer part did not
necessarily indicate an enhanced behavior. The test results contribute
to the characterization of the connection behavior between RC beam -
steel column and can be used to calibrate numerical models for the
simulation of this type of connection.
Abstract: To determine the potential of a low cost Irish
engineered timber product to replace high cost solid timber for use in
bending active structures such as gridshells a single Irish engineered
timber product in the form of orientated strand board (OSB) was
selected. A comparative study of OSB and solid timber was carried
out to determine the optimum properties that make a material suitable
for use in gridshells. Three parameters were identified to be relevant
in the selection of a material for gridshells. These three parameters
are the strength to stiffness ratio, the flexural stiffness of
commercially available sections, and the variability of material and
section properties. It is shown that when comparing OSB against
solid timber, OSB is a more suitable material for use in gridshells that
are at the smaller end of the scale and that have tight radii of
curvature. Typically, for solid timber materials, stiffness is used as an
indicator for strength and engineered timber is no different. Thus, low
flexural stiffness would mean low flexural strength. However, when
it comes to bending active gridshells, OSB offers a significant
advantage. By the addition of multiple layers, an increased section
size is created, thus endowing the structure with higher stiffness and
higher strength from initial low stiffness and low strength materials
while still maintaining tight radii of curvature. This allows OSB to
compete with solid timber on large scale gridshells. Additionally, a
preliminary sustainability study using a set of sustainability indicators
was carried out to determine the relative sustainability of building a
large-scale gridshell in Ireland with a primary focus on economic
viability but a mention is also given to social and environmental
aspects. For this, the Savill garden gridshell in the UK was used as
the functional unit with the sustainability of the structural roof
skeleton constructed from UK larch solid timber being compared
with the same structure using Irish OSB. Albeit that the advantages of
using commercially available OSB in a bending active gridshell are
marginal and limited to specific gridshell applications, further study
into an optimised engineered timber product is merited.
Abstract: This paper proposes five level diode clamped Z source
Inverter. The existing PWM techniques used for ZSI are restricted for
two level. The two level Z Source Inverter have high harmonic
distortions which effects the performance of the grid connected PV
system. To improve the performance of the system the number of
voltage levels in the output waveform need to be increased. This
paper presents comparative analysis of a five level diode clamped Z
source Inverter with different carrier based Modified Pulse Width
Modulation techniques. The parameters considered for comparison
are output voltage, voltage gain, voltage stress across switch and total
harmonic distortion when powered by same DC supply. Analytical
results are verified using MATLAB.
Abstract: Most people today are aware that global climate
change is not just a scientific theory but also a fact with worldwide
consequences. Global climate change is due to rapid urbanization,
industrialization, high population growth and current vulnerability of
the climatic condition. Water is becoming scarce as a result of global
climate change. To mitigate the problem arising due to global climate
change and its drought effect, harvesting rainwater from green roofs,
an environmentally-friendly and versatile technology, is becoming
one of the best assessment criteria and gaining attention in Malaysia.
This paper addresses the sustainability of green roofs and examines
the quality of water harvested from green roofs in comparison to
rainwater. The factors that affect the quality of such water, taking
into account, for example, roofing materials, climatic conditions, the
frequency of rainfall frequency and the first flush. A green roof was
installed on the Humid Tropic Centre (HTC) is a place of the study
on monitoring program for urban Stormwater Management Manual
for Malaysia (MSMA), Eco-Hydrological Project in Kuala Lumpur,
and the rainwater was harvested and evaluated on the basis of four
parameters i.e., conductivity, dissolved oxygen (DO), pH and
temperature. These parameters were found to fall between Class I and
Class III of the Interim National Water Quality Standards (INWQS)
and the Water Quality Index (WQI). Some preliminary treatment
such as disinfection and filtration could likely to improve the value of
these parameters to class I. This review paper clearly indicates that
there is a need for more research to address other microbiological and
chemical quality parameters to ensure that the harvested water is
suitable for use potable water for domestic purposes. The change in
all physical, chemical and microbiological parameters with respect to
storage time will be a major focus of future studies in this field.
Abstract: Array-based gene expression analysis is a powerful
tool to profile expression of genes and to generate information on
therapeutic effects of new anti-cancer compounds. Anti-apoptotic
effect of thymoquinone was studied in MCF7 breast cancer cell line
using gene expression profiling with cDNA microarray. The purity
and yield of RNA samples were determined using RNeasyPlus Mini
kit. The Agilent RNA 6000 NanoLabChip kit evaluated the quantity
of the RNA samples. AffinityScript RT oligo-dT promoter primer
was used to generate cDNA strands. T7 RNA polymerase was used to
convert cDNA to cRNA. The cRNA samples and human universal
reference RNA were labelled with Cy-3-CTP and Cy-5-CTP,
respectively. Feature Extraction and GeneSpring softwares analysed
the data. The single experiment analysis revealed involvement of 64
pathways with up-regulated genes and 78 pathways with downregulated
genes. The MAPK and p38-MAPK pathways were
inhibited due to the up-regulation of PTPRR gene. The inhibition of
p38-MAPK suggested up-regulation of TGF-ß pathway. Inhibition of
p38-MAPK caused up-regulation of TP53 and down-regulation of
Bcl2 genes indicating involvement of intrinsic apoptotic pathway.
Down-regulation of CARD16 gene as an adaptor molecule regulated
CASP1 and suggested necrosis-like programmed cell death and
involvement of caspase in apoptosis. Furthermore, down-regulation
of GPCR, EGF-EGFR signalling pathways suggested reduction of
ER. Involvement of AhR pathway which control cytochrome P450
and glucuronidation pathways showed metabolism of Thymoquinone.
The findings showed differential expression of several genes in
apoptosis pathways with thymoquinone treatment in estrogen
receptor-positive breast cancer cells.
Abstract: The check-in area of airport terminal is one of the
busiest sections at airports at certain periods. The passengers are
subjected to queues and delays during the check-in process. These
delays and queues are due to constraints in the capacity of service
facilities. In this project, the airport terminal is decomposed into
several check-in areas. The airport check-in scheduling problem
requires both a deterministic (integer programming) and stochastic
(simulation) approach. Integer programming formulations are
provided to minimize the total number of counters in each check-in
area under the realistic constraint that counters for one and the same
flight should be adjacent and the desired number of counters
remaining in each area should be fixed during check-in operations.
By using simulation, the airport system can be modeled to study the
effects of various parameters such as number of passengers on a
flight and check-in counter opening and closing time.
Abstract: Object-oriented modeling is spreading in current
simulation of physiological systems through the use of the individual
components of the model and its interconnections to define the
underlying dynamic equations. In this paper we describe the use of
both the SIMSCAPE and MODELICA simulation environments in
the object-oriented modeling of the closed loop cardiovascular
system. The performance of the controlled system was analyzed by
simulation in light of the existing hypothesis and validation tests
previously performed with physiological data. The described
approach represents a valuable tool in the teaching of physiology for
graduate medical students.