Abstract: The aim of this article is to narrate the utility of novel simulation approach i.e. convolution method to predict blood concentration of drug utilizing dissolution data of salbutamol sulphate microparticulate formulations with different release patterns (1:1, 1:2 and 1:3, drug:polymer). Dissolution apparatus II USP 2007 and 900 ml double distilled water stirrd at 50 rpm was employed for dissolution analysis. From dissolution data, blood drug concentration was determined, and in return predicted blood drug concentration data was used to calculate the pharmacokinetic parameters i.e. Cmax, Tmax, and AUC. Convolution is a good biwaiver technique; however its better utility needs it application in the conditions where biorelevant dissolution media are used.
Abstract: 20 years of dentistry was a period of transition from
communist to market economy but Romanian doctors have
insufficient management knowledge. Recently, the need for modern
management has increased due to technologies and superior materials
appearance, as patient-s demands.
Research goal is to increase efficiency by evaluating dental
medical office cost categories in real pricing procedures.
Empirical research is based on guided study that includes
information about the association between categories of cost
perception and therapeutic procedures commonly used in dental
offices.
Due to the obtained results to identify all the labours that make up
a settled procedure costs were determined for each procedure.
Financial evaluation software was created with the main functions:
introducing and maintaining patient records, treatment and
appointments made, procedures cost and monitoring office
productivity.
We believe that the study results can significantly improve the
financial management of dental offices, increasing the effectiveness
and quality of services.
Abstract: The paper reports the preparation and photocatalytic
activity of ZnO/SnO2 and SnO2 nanoparticles. These nanoparticles
were synthesized by hydrothermal method. The products were
characterized by X-ray diffraction (XRD) and scanning electron
microscopy (SEM). Their grain sizes are about 50-100 nm. The
photocatalytic activities of these materials were investigated for
congo red removal from aqueous solution under UV light irradiation.
It was shown that the use of ZnO/SnO2 as photocatalyst have better
photocatalytic activity for degradation of congo red than SnO2 or
TiO2 (anatase, particle size: 30nm) alone.
Abstract: Nowadays, one of the most important problems of the
metropolises and the world large cities is the habitant traffic difficulty
and lack of sufficient parking site for the vehicles. Esfahan city as the
third metropolis of Iran has encountered with the vehicles parkingplace
problems in the most parts of fourteen regions of the city. The
non principled and non systematic dispersal and lack of parking sites
in the city has created an unfavorable status for its traffic and has
caused the air and sound pollutions increase; in addition, it wastes the
most portions of the citizenship and travelers' charge and time in
urban pathways and disturbs their mental and psychical calmness,
thus leads to their intensive dissatisfaction. In this study, by the usage
of AHP model in GIS environment, the effective criteria in selecting
the public parking sites have been combined with each other, and the
results of the created layers overlapping represent the parking
utilitarian vastness and widths. The achieved results of this research
indicate the pretty appropriate public parking sites selection in region
number 3 of Esfahan; but inconsequential dispersal and lack of these
parking sites in this region have caused abundant transportation
problems in Esfahan city.
Abstract: This paper presents the optimal controller design of
the generator control unit in the aircraft power system. The adaptive
tabu search technique is applied to tune the controller parameters
until the best terminal output voltage of generator is achieved. The
output response from the system with the controllers designed by the
proposed technique is compared with those from the conventional
method. The transient simulations using the commercial software
package show that the controllers designed from the adaptive tabu
search algorithm can provide the better output performance compared
with the result from the classical method. The proposed design
technique is very flexible and useful for electrical aircraft engineers.
Abstract: Plackett-Burman statistical screening of media
constituents and operational conditions for extracellular lipase
production from isolate Trichoderma viride has been carried out in
submerged fermentation. This statistical design is used in the early
stages of experimentation to screen out unimportant factors from a
large number of possible factors. This design involves screening of
up to 'n-1' variables in just 'n' number of experiments. Regression
coefficients and t-values were calculated by subjecting the
experimental data to statistical analysis using Minitab version 15.
The effects of nine process variables were studied in twelve
experimental trials. Maximum lipase activity of 7.83 μmol /ml /min
was obtained in the 6th trail. Pareto chart illustrates the order of
significance of the variables affecting the lipase production. The
present study concludes that the most significant variables affecting
lipase production were found to be palm oil, yeast extract, K2HPO4,
MgSO4 and CaCl2.
Abstract: A design flow of multi-standard down-conversion
CMOS mixers for three modern standards: Global System Mobile,
Digital Enhanced Cordless Telephone and Universal Mobile
Telecommunication Systems is presented. Three active mixer-s
structures are studied. The first is based on the Gilbert cell which
gives a tolerable noise figure and linearity with a low conversion
gain. The second and third structures use the current bleeding and
charge injection techniques in order to increase the conversion gain.
An improvement of about 2 dB of the conversion gain is achieved
without a considerable degradation of the other characteristics. The
models used for noise figure, conversion gain and IIP3 used are
studied. This study describes the nature of trade-offs inherent in such
structures and gives insights that help in identifying which structure
is better for given conditions.
Abstract: Analytical investigation of the sedimentation
processes in the river engineering and hydraulic structures is of vital
importance as this can affect water supply for the cultivating lands in
the command area. The reason being that gradual sediment formation
behind the reservoir can reduce the nominal capacity of these dams.
The aim of the present paper is to analytically investigate
sedimentation process along the river course and behind the storage
reservoirs in general and the Eastern Intake of the Dez Diversion weir
in particular using the SHARC software. Results of the model
indicated the water level at 115.97m whereas the real time
measurement from the river cross section was 115.98 m which
suggests a significantly close relation between them. The average
transported sediment load in the river was measured at 0.25mm ,
from which it can be concluded that nearly 100% of the suspended
loads in river are moving which suggests no sediment settling but
indicates that almost all sediment loads enters into the intake. It was
further showed the average sediment diameter entering the intake to
be 0.293 mm which in turn suggests that about 85% of suspended
sediments in the river entre the intake. Comparison of the results
from the SHARC model with those obtained form the SSIIM
software suggests quite similar outputs but distinguishing the
SHARC model as more appropriate for the analysis of simpler
problems than other model.
Abstract: For cognitive radio networks, there is a major
spectrum sensing problem, i.e. dynamic spectrum management. It is
an important issue to sense and identify the spectrum holes in
cognitive radio networks. The first-order derivative scheme is usually
used to detect the edge of the spectrum. In this paper, a novel
spectrum sensing technique for cognitive radio is presented. The
proposed algorithm offers efficient edge detection. Then, simulation
results show the performance of the first-order derivative scheme and
the proposed scheme and depict that the proposed scheme obtains
better performance than does the first-order derivative scheme.
Abstract: In this study, single nozzle method used for
electrospinning technique which composite polymer solution with
cellulose nanowiskers (CNW) was treated by ultrasonic sonificator
have been compared with coaxial (double) nozzle method, in terms of
mechanical, thermal and morphological properties of composite
nanofiber. The effect of water content in composite polymer solution
on properties of nanofiber has also been examined. It has been seen
that single nozzle method which polymer solution does not contain
water has better results than that of coaxial method, in terms of
mechanical, thermal and morphological properties of nanofiber.
However, it is necessary to make an optimization study on setting
condition of ultrasonic treatment to get better dispersion of CNW in
composite nanofiber and to get better mechanical and thermal
properties
Abstract: There have been many games developing simulation
of soccer games. Many of these games have been designed with
highly realistic features to attract more users. Many have also
incorporated better artificial intelligent (AI) similar to that in a real
soccer game. One of the challenging issues in a soccer game is the
cooperation, coordination and negotiation among distributed agents
in a multi-agent system. This paper focuses on the incorporation of
multi-agent technique in a soccer game domain. The better the
cooperation of a multi-agent team, the more intelligent the game will
be. Thus, past studies were done on the robotic soccer game because
of the better multi-agent system implementation. From this study, a
better approach and technique of multi-agent behavior could be
select to improve the author-s 2D online soccer game.
Abstract: Message Passing Interface is widely used for Parallel
and Distributed Computing. MPICH and LAM are popular open
source MPIs available to the parallel computing community also
there are commercial MPIs, which performs better than MPICH etc.
In this paper, we discuss a commercial Message Passing Interface, CMPI
(C-DAC Message Passing Interface). C-MPI is an optimized
MPI for CLUMPS. It is found to be faster and more robust compared
to MPICH. We have compared performance of C-MPI and MPICH
on Gigabit Ethernet network.
Abstract: This paper discusses a qualitative simulator QRiOM
that uses Qualitative Reasoning (QR) technique, and a process-based
ontology to model, simulate and explain the behaviour of selected
organic reactions. Learning organic reactions requires the application
of domain knowledge at intuitive level, which is difficult to be
programmed using traditional approach. The main objective of
QRiOM is to help learners gain a better understanding of the
fundamental organic reaction concepts, and to improve their
conceptual comprehension on the subject by analyzing the multiple
forms of explanation generated by the software. This paper focuses
on the generation of explanation based on causal theories to explicate
various phenomena in the chemistry subject. QRiOM has been tested
with three classes problems related to organic chemistry, with
encouraging results. This paper also presents the results of
preliminary evaluation of QRiOM that reveal its explanation
capability and usefulness.
Abstract: Implementing Information Technology/ Information
System (IT/IS) is critical for every industry as its potential benefits
have been to motivate many industries including the Malaysian
construction industry to invest in it. To successfully implement IT/IS
has become the major concern for every organisation. Identifying the
critical success factors (CSFs) has become the main agenda for
researchers, academicians and practitioners due to the wide number
of failures reported. This research paper seeks to identify the CSFs
that influence the successful implementation of IT/IS in construction
industry in Malaysia. Limited factors relating to people issue will be
highlighted here to showcase some as it becomes one of the major
contributing factors to the failure. Three (3) organisations have
participated in this study. Semi-structured interviews are employed as
they offer sufficient flexibility to ensure that all relevant factors are
covered. Several key issues contributing to successful
implementations of IT/IS are identified. The results of this study
reveal that top management support, communication, user
involvement, IT staff roles and responsibility, training/skills, leader/
IT Leader, organisation culture, knowledge/ experience, motivation,
awareness, focus and ambition, satisfaction, teamwork/ collaboration,
willingness to change, attitude, commitment, management style,
interest in IT, employee behaviour towards collaborative
environment, trust, interpersonal relationship, personal characteristic
and competencies are significantly associated with the successful
implementations of IT/IS. It is anticipated that this study will create
awareness and contribute to a better understanding amongst
construction industry players and will assist them to successfully
implement IT/IS.
Abstract: Cost contribution arrangements (CCAs) and Cost
sharing agreements (CCAs) belong to the tools of modern finance
management. Costs spend by associated enterprises on developing
producing or obtaining assets, services or rights (in general -
benefits) are used for tax optimizing too. The main purpose of joint
research and development, producing or obtaining benefits is to
lower these costs as much as possible or to maximize the benefits. In
this article is mentioned the problematic of transfer pricing and arm's
length principle with connection of CCAs, CSAs. Next, there is
mentioned how to settle participation shares of the total cost and
benefits contributions with respect to the OECD Transfer pricing for
MNEs Guidelines and with respect to other significant regulations.
Abstract: Truly successful bloggers, navigating the public to know them, often use their blogs as a way to better communicate with customers. Integrating with marketing tools, storytelling can be regarded as one of the most effective ways that businesses can follow to gain competitive edge. Even though the literature on marketing contains much discussion of traditional vehicles, the issue of business blogs applying storytelling has, as yet, received little attention. In the exploration stage, this paper identifies four storytelling disciplines and then presents a road map to business blogging. This paper also provides a two-path framework for blog storytelling and initiates an issue for further study.
Abstract: In this paper, we focus on the use of knowledge bases
in two different application areas – control of systems with unknown
or strongly nonlinear models (i.e. hardly controllable by the classical
methods), and robot motion planning in eight directions. The first
one deals with fuzzy logic and the paper presents approaches for
setting and aggregating the rules of a knowledge base. Te second one
is concentrated on a case-based reasoning strategy for finding the
path in a planar scene with obstacles.
Abstract: The last decade has seen an early majority of people
The last decade, the role of the of the information communication
technologies has increased in improving the social and business life
of people. Today, it is recognized that game could contribute to
enhance virtual rehabilitation by better engaging patients. Our
research study aims to develop a game based system enhancing
cognitive and physical capabilities of elderly people. To this end, the
project aims to develop a low cost hand held system based on
existing game such as Wii, PSP, or Xbox. This paper discusses the
concepts and requirements for developing such game for elderly
people. Based on the requirement elicitation, we intend to develop a
prototype related to sport and dance activities.
Abstract: The bridge vibration due to traffic loading has been a
subject of extensive research during the last decades. A number of
these studies are concerned with the effects of the unevenness of
roadways on the dynamic responses of highway bridges. The road
unevenness is often described as a random process that constitutes
of different wavelengths. Thus, the study focuses on examining
the effects of the random description of roadways on the dynamic
response and its variance. A new setting of variance based sensitivity
analysis is proposed and used to identify and quantify the
contributions of the roadway-s wavelengths to the variance of the
dynamic response. Furthermore, the effect of the vehicle-s speed on
the dynamic response is studied.
Abstract: In this paper, we propose a method to reduce the
various kinds of noise while gathering and recording the
electrocardiogram (ECG) signal. Because of the defects of former
method in the noise elimination of ECG signal, we use translation
invariant (TI) multiwavelet denoising method to the noise elimination.
The advantage of the proposed method is that it may not only remain
the geometrical characteristics of the original ECG signal and keep the
amplitudes of various ECG waveforms efficiently, but also suppress
impulsive noise to some extent. The simulation results indicate that the
proposed method are better than former removing noise method in
aspects of remaining geometrical characteristics of ECG signal and the
signal-to-noise ratio (SNR).