Biotransformation of Artemisinin by using a Novel Soil Isolated Microorganism

Artemisinin is a potential antimalarial drug effective against the multidrug resistant forms of Malarial Parasites. The current production of artemisinin is insufficient to meet the global demand. In the present study microbial biotransformation of arteannuin B, a biogenetic precursor of artemisinin to the later has been investigated. Screening studies carried out on several soil borne microorganisms have yielded one novel species with the bioconversion ability. Crude cell free extract of 72h old culture of the isolate had shown the bioconversion activity. On incubation with the substrate arteannuin B, crude cell free extract of the isolate had shown a bioconversion of 18.54% to artemisinin on molar basis with a specific activity of 0.18 units/mg.

Optimization of Control Parameters for MRR in Injection Flushing Type of EDM on Stainless Steel 304 Workpiece

The operating control parameters of injection flushing type of electrical discharge machining process on stainless steel 304 workpiece with copper tools are being optimized according to its individual machining characteristic i.e. material removal rate (MRR). Lower MRR during EDM machining process may decrease its- machining productivity. Hence, the quality characteristic for MRR is set to higher-the-better to achieve the optimum machining productivity. Taguchi method has been used for the construction, layout and analysis of the experiment for each of the machining characteristic for the MRR. The use of Taguchi method in the experiment saves a lot of time and cost of preparing and machining the experiment samples. Therefore, an L18 Orthogonal array which was the fundamental component in the statistical design of experiments has been used to plan the experiments and Analysis of Variance (ANOVA) is used to determine the optimum machining parameters for this machining characteristic. The control parameters selected for this optimization experiments are polarity, pulse on duration, discharge current, discharge voltage, machining depth, machining diameter and dielectric liquid pressure. The result had shown that the higher the discharge voltage, the higher will be the MRR.

Isotropic Stress Distribution in Cu/(001) Fe Two Sheets

The nanotechnology based on epitaxial systems includes single or arranged misfit dislocations. In general, whatever is the type of dislocation or the geometry of the array formed by the dislocations; it is important for experimental studies to know exactly the stress distribution for which there is no analytical expression [1, 2]. This work, using a numerical analysis, deals with relaxation of epitaxial layers having at their interface a periodic network of edge misfit dislocations. The stress distribution is estimated by using isotropic elasticity. The results show that the thickness of the two sheets is a crucial parameter in the stress distributions and then in the profile of the two sheets. A comparative study between the case of single dislocation and the case of parallel network shows that the layers relaxed better when the interface is covered by a parallel arrangement of misfit. Consequently, a single dislocation at the interface produces an important stress field which can be reduced by inserting a parallel network of dislocations with suitable periodicity.

Internal Surface Measurement of Nanoparticle with Polarization-interferometric Nonlinear Confocal Microscope

Polarization-interferometric nonlinear confocal microscopy is proposed for measuring a nano-sized particle with optical anisotropy. The anisotropy in the particle was spectroscopically imaged through a three-dimensional distribution of third-order nonlinear dielectric polarization photoinduced.

A Novel Approach for Beneficiation and Dewatering of Coal Fines for Indian Coal Preparation Plant

An attempt has been made to beneficiate the Indian coking coal fines by a combination of Spiral, flotation and Oleo Flotation processes. Beneficiation studies were also carried out on - 0.5mm coal fines using flotation and oleo flotation by splitting at size 0.063mm.Size fraction of 0.5mm-0.063mm and -0.063mm size were treated in flotation and Oleo flotation respectively. The washability studies on the fraction 3-0.5 mm indicated that good separation may be achieved when it is fed in a spiral. Combined product of Spiral, Flotation and Oleo Flotation has given a significant yield at acceptable ash%. Studies were also conducted to see the dewatering of combined product by batch type centrifuge. It may further be suggested that combination of different processes may be used to treat the -3 mm fraction in an integrated manner to achieve the yield at the desired ash level. The treatment of the 3/1 mm -0.5 mm size fraction by spiral,-0.5-0.63 mm by conventional froth flotation and - 0.063 fractions by oleo flotation may provide a complete solution of beneficiation and dewatering of coal fines, and can effectively address the environmental problems caused by coal fines.

Implicit Authorization Mechanism of Object-Oriented Database

Due to its special data structure and manipulative principle, Object-Oriented Database (OODB) has a particular security protection and authorization methods. This paper first introduces the features of security mechanism about OODB, and then talked about authorization checking process of OODB. Implicit authorization mechanism is based on the subject hierarchies, object hierarchies and access hierarchies of the security authorization modes, and simplifies the authorization mode. In addition, to combine with other authorization mechanisms, implicit authorization can make protection on the authorization of OODB expediently and effectively.

Multiple Intelligences Development of Athletes: Examination on Dominant Intelligences

The study attempted to identify the dominant intelligences of athletes by comparing the developmental differences of multiple intelligences between athletes and non-athletes. The weekly specialized training hours and years of specialized training was examined to see how it can predict the dominant intelligence with the age factor controlled. There were 355 participants in the research (202 athletes and 153 non-athletes). Collected data were analyzed with one-way MANOVA and multiple hierarchical regression. The results suggested the dominant intelligences of athletes were Interpersonal Intelligence, Bodily-Kinesthetic Intelligence, and Intrapersonal Intelligence. The weekly specialized training hours and years of specialized training could effectively predict the Interpersonal Intelligence, Bodily-Kinesthetic Intelligence, and Intrapersonal Intelligence of athletes. The author suggested the future studies could focus on the theory construction of weekly specialized training and years of specialized training. Also, the studies on using “Bridge strategy" by the athletes to guide disadvantage intelligences with dominant intelligences are highly valued.

Factors Affecting the e-Business Adoption among the Home-Based Businesses (HBBs) in Malaysia

Research in e-Business has been growing tremendously covering all related aspects such as adoption issues, e- Business models, strategies, etc. This research aims to explore the potential of adopting e-Business for a micro size business operating from home called home-based businesses (HBBs). In Malaysia, the HBB industry started many years ago and were mostly monopolized by women or housewives managed as a part-time job to support their family economy. Today, things have changed. The availability of the Internet technology and the emergence of e-Business concept promote the evolution of HBBs, which have been adopted as another alternative as a professional career for women without neglecting their family needs especially the children. Although this study is confined to a limited sample size and within geographical biasness, the findings show that it concurs with previous large scale studies. In this study, both qualitative and quantitative methods were used and data were gathered using triangulation methods via interview, direct observation, document analysis and survey questionnaires. This paper discusses the literature review, research methods and findings pertaining to e-Business adoption factors that influence the HBBs in Malaysia.

Sewage Sludge Management in Egypt: Current Status and Perspectives towards a Sustainable Agricultural Use

The present disposal routes of sewage sludge represent a critical environmental issue in Egypt. Recently, there has been an increasing concern about sewage sludge management due to the environmental risks, which resulted from the fast expansion of wastewater treatment plants without equal attention in dealing with the produced sludge. This paper discusses the current situation of sewage sludge management in Egypt presenting a brief overview of the existing wastewater treatment plants, sludge production and characteristics as well as options of beneficial use and potential demand of sewage sludge under Egyptian conditions. The characteristics of sewage sludge are discussed considering the results of own sampling and analysis as well as previous studies. Furthermore, alternative treatment scenarios for sewage sludge, which have been recently developed in Egypt, are discussed and perspectives for a sustainable agricultural use are outlined.

Modeling of a Novel Dual-Belt Continuously Variable Transmission for Automobiles

It is believed that continuously variable transmission (CVT) will dominate the automotive transmissions in the future. The most popular design is Van Doorne-s CVT with single metal pushing V-belt. However, it is only applicable to low power passenger cars because its major limitation is low torque capacity. Therefore, this research studies a novel dual-belt CVT system to overcome the limitation of traditional single-belt CVT, such that it can be applicable to the heavy-duty vehicles. This paper presents the mathematical model of the design and its experimental verification. Experimental and simulated results show that the model developed is valid and the proposed dual-belt CVT can really overcome the traditional limitation of single-belt Van Doorne-s CVT.

Thermomechanical Studies in Glass/Epoxy Composite Specimen during Tensile Loading

This paper presents the results of thermo-mechanical characterization of Glass/Epoxy composite specimens using Infrared Thermography technique. The specimens used for the study were fabricated in-house with three different lay-up sequences and tested on a servo hydraulic machine under uni-axial loading. Infrared Camera was used for on-line monitoring surface temperature changes of composite specimens during tensile deformation. Experimental results showed that thermomechanical characteristics of each type of specimens were distinct. Temperature was found to be decreasing linearly with increasing tensile stress in the elastic region due to thermo-elastic effect. Yield point could be observed by monitoring the change in temperature profile during tensile testing and this value could be correlated with the results obtained from stress-strain response. The extent of prior plastic deformation in the post-yield region influenced the slopes of temperature response during tensile loading. Partial unloading and reloading of specimens post-yield results in change in slope in elastic and plastic regions of composite specimens.

Investigation of Monochromatization Light Effect at Molecular/Atomic Level in Electronegative-Electropositive Gas Mixtures Plasma

In electronegative-electropositive gas mixtures plasma, at a total pressure varying in the range of ten to hundred Torr, the appearance of a quasi-mochromatization effect of the emitted radiation was reported. This radiation could be the result of the generating mechanisms at molecular level, which is the case of the excimer radiation but also at atomic level. Thus, in the last case, in (Ne+1%Ar/Xe+H2) gas mixtures plasma in a dielectric barrier discharge, this effect, called M-effect, consists in the reduction of the discharge emission spectrum practice at one single, strong spectral line with λ = 585.3 nm. The present paper is concerned with the characteristics comparative investigation of the principal reaction mechanisms involved in the quasi-monochromatization effect existence in the case of the excimer radiation, respectively of the Meffect. Also, the paper points out the role of the metastable electronegative atoms in the appearance of the monochromatization – effect at atomic level.

Improvement of Energy Efficiency using Porous Fins in Heat Exchangers

The forced convection heat transfer in high porosity metal-foam filled tube heat exchangers are studied in this paper. The Brinkman Darcy momentum model and two energy equations for both solid and fluid phases in porous media are employed .The study shows that using metal-foams can significantly improve the heat transfer in heat exchangers.

Flexible Follower Response of a Translating Cam with Four Different Profiles for Rise-Dwell-Fall-Dwell motion

The flexible follower response of a translating cam with four different profiles for rise-dwell-fall-dwell (RDFD) motion is investigated. The cycloidal displacement motion, the modified sinusoidal acceleration motion, the modified trapezoidal acceleration motion, and the 3-4-5 polynomial motion are employed to describe the rise and the fall motions of the follower and the associated four kinds of cam profiles are studied. Since the follower flexibility is considered, the contact point of the roller and the cam is an unknown. Two geometric constraints formulated to restrain the unknown position are substituted into Hamilton-s principle with Lagrange multipliers. Applying the assumed mode method, one can obtain the governing equations of motion as non-linear differential-algebraic equations. The equations are solved using Runge-Kutta method. Then, the responses of the flexible follower undergoing the four different motions are investigated in time domain and in frequency domain.

Monotonic and Cyclic J-integral Estimation for Through-Wall Cracked Straight Pipes

The evaluation of energy release rate and centre Crack Opening Displacement (COD) for circumferential Through-Wall Cracked (TWC) pipes is an important issue in the assessment of critical crack length for unstable fracture. The ability to predict crack growth continues to be an important component of research for several structural materials. Crack growth predictions can aid the understanding of the useful life of a structural component and the determination of inspection intervals and criteria. In this context, studies were carried out at CSIR-SERC on Nuclear Power Plant (NPP) piping components subjected to monotonic as well as cyclic loading to assess the damage for crack growth due to low-cycle fatigue in circumferentially TWC pipes.

Biosorption of Heavy Metals Contaminating the Wonderfonteinspruit Catchment Area using Desmodesmus sp.

A vast array of biological materials, especially algae have received increasing attention for heavy metal removal. Algae have been proven to be cheaper, more effective for the removal of metallic elements in aqueous solutions. A fresh water algal strain was isolated from Zoo Lake, Johannesburg, South Africa and identified as Desmodesmus sp. This paper investigates the efficacy of Desmodesmus sp.in removing heavy metals contaminating the Wonderfonteinspruit Catchment Area (WCA) water bodies. The biosorption data fitted the pseudo-second order and Langmuir isotherm models. The Langmuir maximum uptakes gave the sequence: Mn2+>Ni2+>Fe2+. The best results for kinetic study was obtained in concentration 120 ppm for Fe3+ and Mn2+, whilst for Ni2+ was at 20 ppm, which is about the same concentrations found in contaminated water in the WCA (Fe3+115 ppm, Mn2+ 121 ppm and Ni2+ 26.5 ppm).

Study the Influence of Chemical Treatment on the Compositional Changes and Defect Structures of ZnS Thin Film

The effect of chemical treatment in CdCl2 on the compositional changes and defect structures of potentially useful ZnS solar cell thin films prepared by vacuum deposition method was studied using the complementary Rutherford backscattering (RBS) and Thermoluminesence (TL) techniques. A series of electron and hole traps are found in the various as deposited samples studied. After treatment, perturbation on the intensity is noted; mobile defect states and charge conversion and/or transfer between defect states are found.

Method of Finding Aerodynamic Characteristic Equations of Missile for Trajectory Simulation

This paper present a new way to find the aerodynamic characteristic equation of missile for the numerical trajectories prediction more accurate. The goal is to obtain the polynomial equation based on two missile characteristic parameters, angle of attack (α ) and flight speed (╬¢ ). First, the understudied missile is modeled and used for flow computational model to compute aerodynamic force and moment. Assume that performance range of understudied missile where range -10< α

Stakeholder Analysis: Who are the Key Actorsin Establishing and Developing Thai Independent Consumer Organizations?

In Thailand, both the 1997 and the current 2007 Thai Constitutions have mentioned the establishment of independent organizations as a new mechanism to play a key role in proposing policy recommendations to national decision-makers in the interest of collective consumers. Over the last ten years, no independent organizations have yet been set up. Evidently, nobody could point out who should be key players in establishing provincial independent consumer bodies. The purpose of this study was to find definitive stakeholders in establishing and developing independent consumer bodies in a Thai context. This was a cross-sectional study between August and September 2007, using a postal questionnaire with telephone follow-up. The questionnaire was designed and used to obtain multiple stakeholder assessment of three key attributes (power, interest and influence). Study population was 153 stakeholders associated with policy decision-making, formulation and implementation processes of civil-based consumer protection in pilot provinces. The population covered key representatives from five sectors (academics, government officers, business traders, mass media and consumer networks) who participated in the deliberative forums at 10 provinces. A 49.7% response rate was achieved. Data were analyzed, comparing means of three stakeholder attributes and classification of stakeholder typology. The results showed that the provincial health officers were the definitive stakeholders as they had legal power, influence and interest in establishing and sustaining the independent consumer bodies. However, only a few key representatives of the provincial health officers expressed their own paradigm on the civil-based consumer protection. Most provincial health officers put their own standpoint of building civic participation at only a plan-implementation level. For effective policy implementation by the independent consumer bodies, the Thai government should provide budgetary support for the operation of the provincial health officers with their paradigm shift as well as their own clarified standpoint on corporate governance.

Segmentation and Recognition of Handwritten Numeric Chains

In this paper we present an off line system for the recognition of the handwritten numeric chains. Our work is divided in two big parts. The first part is the realization of a recognition system of the isolated handwritten digits. In this case the study is based mainly on the evaluation of neural network performances, trained with the gradient back propagation algorithm. The used parameters to form the input vector of the neural network are extracted on the binary images of the digits by several methods: the distribution sequence, the Barr features and the centred moments of the different projections and profiles. The second part is the extension of our system for the reading of the handwritten numeric chains constituted of a variable number of digits. The vertical projection is used to segment the numeric chain at isolated digits and every digit (or segment) will be presented separately to the entry of the system achieved in the first part (recognition system of the isolated handwritten digits). The result of the recognition of the numeric chain will be displayed at the exit of the global system.