Abstract: MiRNAs participate in gene regulation of translation.
Some studies have investigated the interactions between genes and
intragenic miRNAs. It is important to study the miRNA binding sites
of genes involved in carcinogenesis. RNAHybrid 2.1 and ERNAhybrid
programmes were used to compute the hybridization free
energy of miRNA binding sites. Of these 54 mRNAs, 22.6%, 37.7%,
and 39.7% of miRNA binding sites were present in the 5'UTRs,
CDSs, and 3'UTRs, respectively. The density of the binding sites for
miRNAs in the 5'UTR ranged from 1.6 to 43.2 times and from 1.8 to
8.0 times greater than in the CDS and 3'UTR, respectively. Three
types of miRNA interactions with mRNAs have been revealed: 5'-
dominant canonical, 3'-compensatory, and complementary binding
sites. MiRNAs regulate gene expression, and information on the
interactions between miRNAs and mRNAs could be useful in
molecular medicine. We recommend that newly described sites
undergo validation by experimental investigation.
Abstract: Currently, many types of no-reversible compressed
sound source, represented by MP3 (MPEG Audio Layer-3) are
popular in the world and they are widely used to make the music file
size smaller. The sound data created in this way has less information as
compared to pre-compressed data. The objective of this study is by
analyzing EEG to determine if people can recognize such difference as
differences in sound. A measurement system that can measure and
analyze EEG when a subject listens to music were experimentally
developed. And ten subjects were studied with this system. In this
experiment, a WAVE formatted music data and a MP3 compressed
music data that is made from the WAVE formatted data were
prepared. Each subject was made to hear these music sources at the
same volume. From the results of this experiment, clear differences
were confirmed between two wound sources.
Abstract: Simulations play a major role in education not only because they provide realistic models with which students can interact to acquire real world experiences, but also because they constitute safe environments in which students can repeat processes without any risk in order to perceive easier concepts and theories. Virtual reality is widely recognized as a significant technological advance that can facilitate learning process through the development of highly realistic 3D simulations supporting immersive and interactive features. The objective of this paper is to analyze the influence of virtual reality-s use in chemistry instruction as well as to present an integrated web-based learning environment for the simulation of chemical experiments. The proposed application constitutes a cost-effective solution for both schools and universities without appropriate infrastructure and a valuable tool for distance learning and life-long education in chemistry. Its educational objectives are the familiarization of students with the equipment of a real chemical laboratory and the execution of virtual volumetric analysis experiments with the active participation of students.
Abstract: In this paper, we propose a new hybrid learning model for stock market indices prediction by adding a passive congregation term to the standard hybrid model comprising Particle Swarm Optimization (PSO) with Genetic Algorithm (GA) operators in training Neural Networks (NN). This new passive congregation term is based on the cooperation between different particles in determining new positions rather than depending on the particles selfish thinking without considering other particles positions, thus it enables PSO to perform both the local and global search instead of only doing the local search. Experiment study carried out on the most famous European stock market indices in both long term and short term prediction shows significantly the influence of the passive congregation term in improving the prediction accuracy compared to standard hybrid model.
Abstract: The conventional GA combined with a local search
algorithm, such as the 2-OPT, forms a hybrid genetic algorithm(HGA)
for the traveling salesman problem (TSP). However, the geometric
properties which are problem specific knowledge can be used to
improve the search process of the HGA. Some tour segments (edges)
of TSPs are fine while some maybe too long to appear in a short tour.
This knowledge could constrain GAs to work out with fine tour
segments without considering long tour segments as often.
Consequently, a new algorithm is proposed, called intelligent-OPT
hybrid genetic algorithm (IOHGA), to improve the GA and the 2-OPT
algorithm in order to reduce the search time for the optimal solution.
Based on the geometric properties, all the tour segments are assigned
2-level priorities to distinguish between good and bad genes. A
simulation study was conducted to evaluate the performance of the
IOHGA. The experimental results indicate that in general the IOHGA
could obtain near-optimal solutions with less time and better accuracy
than the hybrid genetic algorithm with simulated annealing algorithm
(HGA(SA)).
Abstract: A theoretical approach to radiation damage evolution
is developed. Stable temporal behavior taking place in solids under
irradiation are examined as phenomena of self-organization in nonequilibrium
systems.
Experimental effects of temporal self-organization in solids under
irradiation are reviewed. Their essential common properties and
features are highlighted and analyzed.
Dynamical model to describe development of self-oscillation of
density of point defects under stationary irradiation is proposed. The
emphasis is the nonlinear couplings between rate of annealing and
density of defects that determine the kind and parameters of an
arising self-oscillation.
The field of parameters (defect generation rate and environment
temperature) at which self-oscillations develop is found. Bifurcation
curve and self-oscillation period near it is obtained.
Abstract: In order to meet environmental norms, Indian fuel
policy aims at producing ultra low sulphur diesel (ULSD) in near
future. A catalyst for meeting such requirements has been developed
and kinetics of this catalytic process is being looked into. In the
present investigations, effect of mass transfer on kinetics of ultra deep
hydrodesulphurization (UDHDS) to produce ULSD has been studied
to determine intrinsic kinetics over a pre-sulphided catalyst.
Experiments have been carried out in a continuous flow micro reactor
operated in the temperature range of 330 to 3600C, whsv of 1 hr-1 at a
pressure of 35 bar, and its parameters estimated. Based on the derived
rate expression and estimated parameters optimum operation range
has been determined for this UDHDS catalyst to obtain ULSD
product.
Abstract: This study endeavors to evaluate the effects of farmers’ training program on the adoption of improved farming practices, the output of rice farming, and the income as well as the profit from rice farming by employing an ex-post non-experimental data in Sierra Leone. It was established that participating in farmers’ training program increased the possibility of adoption of the improved farming activities that were implemented in the study area. Through the training program also, the proceeds from rice production was also established to have increased considerably. These results were in line with the assumption that one of the main constraints on the growth in agricultural output particularly rice cultivation in most African states is the lack of efficient extension programs.
Abstract: Minimum Quantity Lubrication (MQL) technique
obtained a significant attention in machining processes to reduce
environmental loads caused by usage of conventional cutting fluids.
Recently nanofluids are finding an extensive application in the field
of mechanical engineering because of their superior lubrication and
heat dissipation characteristics. This paper investigates the use of a
nanofluid under MQL mode to improve grinding characteristics of
Ti-6Al-4V alloy. Taguchi-s experimental design technique has been
used in the present investigation and a second order model has been
established to predict grinding forces and surface roughness.
Different concentrations of water based Al2O3 nanofluids were
applied in the grinding operation through MQL setup developed in
house and the results have been compared with those of conventional
coolant and pure water. Experimental results showed that grinding
forces reduced significantly when nano cutting fluid was used even at
low concentration of the nano particles and surface finish has been
found to improve with higher concentration of the nano particles.
Abstract: The paper presents a one-dimensional transient
mathematical model of compressible non-isothermal multicomponent
fluid mixture flow in a pipe. The set of the mass,
momentum and enthalpy conservation equations for gas phase is
solved in the model. Thermo-physical properties of multi-component
gas mixture are calculated by solving the Equation of State (EOS)
model. The Soave-Redlich-Kwong (SRK-EOS) model is chosen. Gas
mixture viscosity is calculated on the basis of the Lee-Gonzales-
Eakin (LGE) correlation. Numerical analysis of rapid gas
decompression process in rich and base natural gases is made on the
basis of the proposed mathematical model. The model is successfully
validated on the experimental data [1]. The proposed mathematical
model shows a very good agreement with the experimental data [1] in
a wide range of pressure values and predicts the decompression in
rich and base gas mixtures much better than analytical and
mathematical models, which are available from the open source
literature.
Abstract: Iran is one of the greatest producers of date in the
world. However due to lack of information about its viscoelastic
properties, much of the production downgraded during harvesting
and postharvesting processes. In this study the effect of temperature
and moisture content of product were investigated on stress
relaxation characteristics. Therefore, the freshly harvested date
(kabkab) at tamar stage were put in controlled environment chamber
to obtain different temperature levels (25, 35, 45, and 55 0C) and
moisture contents (8.5, 8.7, 9.2, 15.3, 20, 32.2 %d.b.). A texture
analyzer TAXT2 (Stable Microsystems, UK) was used to apply
uniaxial compression tests. A chamber capable to control temperature
was designed and fabricated around the plunger of texture analyzer to
control the temperature during the experiment. As a new approach a
CCD camera (A4tech, 30 fps) was mounted on a cylindrical glass
probe to scan and record contact area between date and disk.
Afterwards, pictures were analyzed using image processing toolbox
of Matlab software. Individual date fruit was uniaxially compressed
at speed of 1 mm/s. The constant strain of 30% of thickness of date
was applied to the horizontally oriented fruit. To select a suitable
model for describing stress relaxation of date, experimental data were
fitted with three famous stress relaxation models including the
generalized Maxwell, Nussinovitch, and Pelege. The constant in
mentioned model were determined and correlated with temperature
and moisture content of product using non-linear regression analysis.
It was found that Generalized Maxwell and Nussinovitch models
appropriately describe viscoelastic characteristics of date fruits as
compared to Peleg mode.
Abstract: Intercropping is one of the sustainable agricultural
factors. The SPAD meter can be used to predict nitrogen index
reliably, it may also be a useful tool for assessing the relative impact
of weeds on crops. In order to study the effect of weeds on SPAD in
corn (Zea mays L.), sweet basil (Ocimum basilicum L.) and borage
(Borago officinalis L.) in intercropping system, a factorial experiment
was conducted in three replications in 2011. Experimental factors
were included intercropping of corn with sweet basil and borage in
different ratios (100:0, 75:25, 50:50, 25:75 and 0:100 corn: borage or
sweet basil) and weed infestation (weed control and weed
interference). The results showed that intercropping of corn with
sweet basil and borage increased the SPAD value of corn compare to
monoculture in weed interference condition. Sweet basil SPAD value
in weed control treatments (43.66) was more than weed interference
treatments (40.17). Corn could increase the borage SPAD value
compare to monoculture in weed interference treatments.
Abstract: In the recent past, there has been an increasing interest
in applying evolutionary methods to Knowledge Discovery in
Databases (KDD) and a number of successful applications of Genetic
Algorithms (GA) and Genetic Programming (GP) to KDD have been
demonstrated. The most predominant representation of the
discovered knowledge is the standard Production Rules (PRs) in the
form If P Then D. The PRs, however, are unable to handle
exceptions and do not exhibit variable precision. The Censored
Production Rules (CPRs), an extension of PRs, were proposed by
Michalski & Winston that exhibit variable precision and supports an
efficient mechanism for handling exceptions. A CPR is an
augmented production rule of the form:
If P Then D Unless C, where C (Censor) is an exception to the rule.
Such rules are employed in situations, in which the conditional
statement 'If P Then D' holds frequently and the assertion C holds
rarely. By using a rule of this type we are free to ignore the exception
conditions, when the resources needed to establish its presence are
tight or there is simply no information available as to whether it
holds or not. Thus, the 'If P Then D' part of the CPR expresses
important information, while the Unless C part acts only as a switch
and changes the polarity of D to ~D.
This paper presents a classification algorithm based on evolutionary
approach that discovers comprehensible rules with exceptions in the
form of CPRs.
The proposed approach has flexible chromosome encoding, where
each chromosome corresponds to a CPR. Appropriate genetic
operators are suggested and a fitness function is proposed that
incorporates the basic constraints on CPRs. Experimental results are
presented to demonstrate the performance of the proposed algorithm.
Abstract: Principle component analysis is often combined with
the state-of-art classification algorithms to recognize human faces.
However, principle component analysis can only capture these
features contributing to the global characteristics of data because it is a
global feature selection algorithm. It misses those features
contributing to the local characteristics of data because each principal
component only contains some levels of global characteristics of data.
In this study, we present a novel face recognition approach using
non-negative principal component analysis which is added with the
constraint of non-negative to improve data locality and contribute to
elucidating latent data structures. Experiments are performed on the
Cambridge ORL face database. We demonstrate the strong
performances of the algorithm in recognizing human faces in
comparison with PCA and NREMF approaches.
Abstract: Improving performance measures in the construction
processes has been a major concern for managers and decision
makers in the industry. They seek for ways to recognize the key
factors which have the largest effect on the process. Identifying such
factors can guide them to focus on the right parts of the process in
order to gain the best possible result. In the present study design of
experiment (DOE) has been applied to a computer simulation model
of brick laying process to determine significant factors while
productivity has been chosen as the response of the experiment. To
this end, four controllable factors and their interaction have been
experimented and the best factor level has been calculated for each
one. The results indicate that three factors, namely, labor of brick,
labor of mortar and inter arrival time of mortar along with interaction
of labor of brick and labor of mortar are significant.
Abstract: A pot experiment was carried out under controlled
conditions to evaluate the residual effects of different doses of
atrazine+alachlor and foramsulfuron used in corn fields on the
growth and physiology of rapeseed (Brassica napus L.). A split-plot
experiment in CRD with 4 replications was used. The main plots
consisted of herbicide type (atrazine+alachlor mixture and
foramsulfuron) and the sub-plots were different residual doses of the
herbicides (0, 1%, 5%, 10%, 20%, 40%, 50% and 100%). 7 cm
diameter pots were filled with a virgin soil and seeds of rapeseed cv.
Hayola were planted in them. The pots were kept under controlled
conditions for 8 weeks after germination. At harvest, the growth
parameters and the chlorophyll contents of the leaves were
determined. The results showed that the growth of rapeseed plants
was completely prevented at the highest residual doses of the
herbicides (50 and 100 %). The growth parameters of rapeseed plants
were affected by all doses of both types of the herbicide as compared
to the controls. The residual effects of atrazine+alachlor mixture in
reducing the growth parameters of rapeseed were more pronounced
as compared to the residual effects of foramsulfuron alone.
Abstract: Image restoration involves elimination of noise. Filtering techniques were adopted so far to restore images since last five decades. In this paper, we consider the problem of image restoration degraded by a blur function and corrupted by random noise. A method for reducing additive noise in images by explicit analysis of local image statistics is introduced and compared to other noise reduction methods. The proposed method, which makes use of an a priori noise model, has been evaluated on various types of images. Bayesian based algorithms and technique of image processing have been described and substantiated with experimentation using MATLAB.
Abstract: In the present paper, the three-dimensional
temperature field of tool is determined during the machining and
compared with experimental work on C45 workpiece using carbide
cutting tool inserts. During the metal cutting operations, high
temperature is generated in the tool cutting edge which influence on
the rate of tool wear. Temperature is most important characteristic of
machining processes; since many parameters such as cutting speed,
surface quality and cutting forces depend on the temperature and high
temperatures can cause high mechanical stresses which lead to early
tool wear and reduce tool life. Therefore, considerable attention is
paid to determine tool temperatures. The experiments are carried out
for dry and orthogonal machining condition. The results show that
the increase of tool temperature depends on depth of cut and
especially cutting speed in high range of cutting conditions.
Abstract: Recently research on human wayfinding has focused
mainly on mental representations rather than processes of
wayfinding. The objective of this paper is to demonstrate the
rationality behind applying multi-agent simulation paradigm to the
modeling of rescuer team wayfinding in order to develop
computational theory of perceptual wayfinding in crisis situations
using image schemata and affordances, which explains how people
find a specific destination in an unfamiliar building such as a
hospital. The hypothesis of this paper is that successful navigation is
possible if the agents are able to make the correct decision through
well-defined cues in critical cases, so the design of the building
signage is evaluated through the multi-agent-based simulation. In
addition, a special case of wayfinding in a building, finding one-s
way through three hospitals, is used to demonstrate the model.
Thereby, total rescue time for rescue operation during building fire is
computed. This paper discuses the computed rescue time for various
signage localization and provides experimental result for
optimization of building signage design. Therefore the most
appropriate signage design resulted in the shortest total rescue time in
various situations.
Abstract: In this paper, a design methodology to implement low-power and high-speed 2nd order recursive digital Infinite Impulse Response (IIR) filter has been proposed. Since IIR filters suffer from a large number of constant multiplications, the proposed method replaces the constant multiplications by using addition/subtraction and shift operations. The proposed new 6T adder cell is used as the Carry-Save Adder (CSA) to implement addition/subtraction operations in the design of recursive section IIR filter to reduce the propagation delay. Furthermore, high-level algorithms designed for the optimization of the number of CSA blocks are used to reduce the complexity of the IIR filter. The DSCH3 tool is used to generate the schematic of the proposed 6T CSA based shift-adds architecture design and it is analyzed by using Microwind CAD tool to synthesize low-complexity and high-speed IIR filters. The proposed design outperforms in terms of power, propagation delay, area and throughput when compared with MUX-12T, MCIT-7T based CSA adder filter design. It is observed from the experimental results that the proposed 6T based design method can find better IIR filter designs in terms of power and delay than those obtained by using efficient general multipliers.