Abstract: Advanced head and neck cancers are aggressive
tumours, which require aggressive treatment. Treatment efficiency is
often hindered by cancer cell repopulation during radiotherapy,
which is due to various mechanisms triggered by the loss of tumour
cells and involves both stem and differentiated cells. The aim of the
current paper is to present in silico simulations of radiotherapy
schedules on a virtual head and neck tumour grown with biologically
realistic kinetic parameters. Using the linear quadratic formalism of
cell survival after radiotherapy, altered fractionation schedules
employing various treatment breaks for normal tissue recovery are
simulated and repopulation mechanism implemented in order to
evaluate the impact of various cancer cell contribution on tumour
behaviour during irradiation. The model has shown that the timing of
treatment breaks is an important factor influencing tumour control in
rapidly proliferating tissues such as squamous cell carcinomas of the
head and neck. Furthermore, not only stem cells but also
differentiated cells, via the mechanism of abortive division, can
contribute to malignant cell repopulation during treatment.
Abstract: The design and plantwide control of an integrated
plant where the endothermic 1,4-butanediol dehydrogenation and the
exothermic furfural hydrogenation is simultaneously performed in a
single reactor is studied. The reactions can be carried out in an
adiabatic reactor using small hydrogen excess and with reduced
parameter sensitivity. The plant is robust and flexible enough to
allow different production rates of γ-butyrolactone and 2-methyl
furan, keeping high product purities. Rigorous steady state and
dynamic simulations performed in AspenPlus and AspenDynamics to
support the conclusions.
Abstract: Eucalyptus species are well reputed for their
traditional use in Asia as well as in other parts of the world; therefore,
the present study was designed to investigate the antimicrobial and
antioxidant activities associated with essential oils from different
Eucalyptus species. Essential oils from the leaves of six Eucalyptus
species, including: Eucalyptus woodwardi, Eucalyptus stricklandii,
Eucalyptus salubris, Eucalyptus sargentii, Eucalyptus torquata and
Eucalyptus wandoo were separated by hydrodistillation and dried
over anhydrous sodium sulphate. DPPH, ferric reducing antioxidant
power, and hydroxyl radical scavenging activity assays were carried
out to evaluate the antioxidant potential of the oils. The results
indicate that examined oils exhibit substantial antioxidant activities
relative to ascorbic acid. Previously, these oils were evaluated for
their antimicrobial activities, against wide range of bacterial and
fungal strains, and they were shown to possess significant
antimicrobial activities. In this study, further investigation into the
growth kinetics of oil-treated microbial cultures was conducted. The
results clearly demonstrate that the microbial growth was markedly
inhibited when treated with sub-MIC concentrations of the oils.
Taken together, the results obtained indicate a high potential of the
examined essential oils as bioactive oils, for nutraceutical and
medical applications, possessing significant antioxidant and anti
microbial activities.
Abstract: In this paper, a nonlinear Finite Element Analysis
(FEA) was carried out using ANSYS software to build a model able
of predicting the behavior of Reinforced Concrete (RC) beams with
unbonded reinforcement. The FEA model was compared to existing
experimental data by other researchers. The existing experimental
data consisted of 16 beams that varied from structurally sound beams
to beams with unbonded reinforcement with different unbonded
lengths and reinforcement ratios. The model was able to predict the
ultimate flexural strength, load-deflection curve, and crack pattern of
concrete beams with unbonded reinforcement. It was concluded that
when the when the unbonded length is less than 45% of the span,
there will be no decrease in the ultimate flexural strength due to the
loss of bond between the steel reinforcement and the surrounding
concrete regardless of the reinforcement ratio. Moreover, when the
reinforcement ratio is relatively low, there will be no decrease in
ultimate flexural strength regardless of the length of unbond.
Abstract: VACTERL association is a rare disorder with various
congenital malformations. The aetiology remains unknown.
Combination of at least three congenital anomalies of the following
criteria is required for diagnosis: vertebral defects, anal atresia,
cardiac anomalies, tracheo-esophageal fistula, renal anomalies, and
limb defects. The first case was 1-day old male neonate with multiple
congenital anomalies was bore from 28 years old mother. The mother
had history of pregnancy with lymphocyte therapy. His anomalies
included: defects in thoracic and lumbar vertebral, anal atresia,
bilateral hydronephrosis, atrial septal defect, and lower limb
abnormality. Other anomalies were cryptorchidism and nasal canal
narrowing. The second case was born with 32 weeks gestational age
from mother with history of pregnancy with lymphocyte therapy. He
had thoracic vertebral defect, cardiac anomalies and renal defect.
diagnosis based on clinical finding is VACTERL association. Early
diagnosis is very important to investigation and treatment of other
coexistence anomalies. VACTERL association in mothers with
history of pregnancy with lymphocyte therapy has suggested possibly
of relationship between VACTERL association and this method of
pregnancy.
Abstract: The California Bearing Ratio (CBR) has been
acknowledged as an important parameter to characterize the bearing
capacity of earth structures, such as earth dams, road embankments,
airport runways, bridge abutments and pavements. Technically, the
CBR test can be carried out in the laboratory or in the field. The CBR
test is time-consuming and is infrequently performed due to the
equipment needed and the fact that the field moisture content keeps
changing over time. Over the years, many correlations have been
developed for the prediction of CBR by various researchers,
including the dynamic cone penetrometer, undrained shear strength
and Clegg impact hammer. This paper reports and discusses some of
the results from a study on the prediction of CBR. In the current
study, the CBR test was performed in the laboratory on some finegrained
subgrade soils collected from various locations in Victoria.
Based on the test results, a satisfactory empirical correlation was
found between the CBR and the physical properties of the
experimental soils.
Abstract: Water contamination by toxic compound is one of the serious environmental problems today. These toxic compounds mostly originated from industrial effluents, agriculture, natural sources and human waste. These studies focus on modification of multiwalled carbon nanotube (MWCNTs) with nanoparticle of calixarene and explore the possibility of using this modification for the remediation of cadmium in water. The nanocomposites were prepared by dissolving calixarene in chloroform solution as solvent, followed by additional multiwalled carbon nanotube (MWCNTs) then sonication process for 3 hour and fabricated the nanocomposites on substrate by spin coating method. Finally, the nanocomposites were tested on cadmium ion (10 mg/ml). The morphology of nanocomposites was investigated by FESEM showing the formation of calixarene on the outer walls of carbon nanotube and cadmium ion also clearly seen from the micrograph. This formation was supported by using energy dispersive x-ray (EDX). The presence of cadmium ions in the films, leads to some changes in the surface potential and Fourier Transform Infrared spectroscopy (FTIR).The nanocomposites MWCNTs-calixarene have potential for development of sensor for pollutant monitoring and nanoelectronics devices applications.
Abstract: This paper presents the details of a numerical study of
buckling and post buckling behaviour of laminated carbon fiber
reinforced plastic (CFRP) thin-walled cylindrical shell under axial
compression using asymmetric meshing technique (AMT) by
ABAQUS. AMT is considered to be a new perturbation method to
introduce disturbance without changing geometry, boundary
conditions or loading conditions. Asymmetric meshing affects both
predicted buckling load and buckling mode shapes. Cylindrical shell
having lay-up orientation [0^o/+45^o/-45^o/0^o] with radius to thickness
ratio (R/t) equal to 265 and length to radius ratio (L/R) equal to 1.5 is
analysed numerically. A series of numerical simulations
(experiments) are carried out with symmetric and asymmetric
meshing to study the effect of asymmetric meshing on predicted
buckling behaviour. Asymmetric meshing technique is employed in
both axial direction and circumferential direction separately using
two different methods, first by changing the shell element size and
varying the total number elements, and second by varying the shell
element size and keeping total number of elements constant. The
results of linear analysis (Eigenvalue analysis) and non-linear
analysis (Riks analysis) using symmetric meshing agree well with
analytical results. The results of numerical analysis are presented in
form of non-dimensional load factor, which is the ratio of buckling
load using asymmetric meshing technique to buckling load using
symmetric meshing technique. Using AMT, load factor has about 2%
variation for linear eigenvalue analysis and about 2% variation for
non-linear Riks analysis. The behaviour of load end-shortening curve
for pre-buckling is same for both symmetric and asymmetric meshing
but for asymmetric meshing curve behaviour in post-buckling
becomes extraordinarily complex. The major conclusions are:
different methods of AMT have small influence on predicted
buckling load and significant influence on load displacement curve
behaviour in post buckling; AMT in axial direction and AMT in
circumferential direction have different influence on buckling load
and load displacement curve in post-buckling.
Abstract: The study of organisations’ information security
cultures has attracted scholars as well as healthcare services industry
to research the topic and find appropriate tools and approaches to
develop a positive culture. The vast majority of studies in Saudi
national health services are on the use of technology to protect and
secure health services information. On the other hand, there is a lack
of research on the role and impact of an organisation’s cultural
dimensions on information security. This research investigated and
analysed the role and impact of cultural dimensions on information
security in Saudi Arabia health service. Hypotheses were tested and
two surveys were carried out in order to collect data and information
from three major hospitals in Saudi Arabia (SA). The first survey
identified the main cultural-dimension problems in SA health
services and developed an initial information security culture
framework model. The second survey evaluated and tested the
developed framework model to test its usefulness, reliability and
applicability. The model is based on human behaviour theory, where
the individual’s attitude is the key element of the individual’s
intention to behave as well as of his or her actual behaviour. The
research identified a set of cultural and sub-cultural dimensions in SA
health information security and services.
Abstract: High Peak to Average Power Ratio (PAPR) of the
transmitted signal is a serious problem in multicarrier systems (MC),
such as Orthogonal Frequency Division Multiplexing (OFDM), or in
Multi-Carrier Code Division Multiple Access (MC-CDMA) systems,
due to large number of subcarriers. This effect is possible reduce with
some PAPR reduction techniques. Spreading sequences at the
presence of Saleh and Rapp models of high power amplifier (HPA)
have big influence on the behavior of system. In this paper we
investigate the bit-error-rate (BER) performance of MC-CDMA
systems. Basically we can see from simulations that the MC-CDMA
system with Iterative algorithm can be providing significantly better
results than the MC-CDMA system. The results of our analyses are
verified via simulation.
Abstract: The adsorption efficiency of fired clayey pellets of 5
and 8 mm diameter size for Cu(II) and Zn(II) ion removal from a
waste printing developer was studied. In order to investigate the
influence of contact time, adsorbent mass and pellet size on the
adsorption efficiency the batch mode was carried out. Faster uptake
of copper ion was obtained with the fired clay pellets of 5 mm
diameter size within 30 minutes. The pellets of 8 mm diameter size
showed the higher equilibrium time (60 to 75 minutes) for copper and
zinc ion. The results pointed out that adsorption efficiency increases
with the increase of adsorbent mass. The maximal efficiency is
different for Cu(II) and Zn(II) ion due to the pellet size. Therefore,
the fired clay pellets of 5 mm diameter size present an effective
adsorbent for Cu(II) ion removal (adsorption efficiency is 63.6%),
whereas the fired clay pellets of 8 mm diameter size are the best
alternative for Zn(II) ion removal (adsorption efficiency is 92.8%)
from a waste printing developer.
Abstract: The main objective of this paper is study the influence
of carbon nano-tubes fibers and nano silica fibers on the
characteristic compressive strength and flexural strength on concrete
and cement mortar. Twelve tested specimens were tested with square
section its dimensions (4040 160) mm, divided into four groups.
The first and second group studied the effect of carbon nano-tubes
(CNTs) fibers with different percentage equal to 0.0, 0.11%, 0.22%,
and 0.33% by weight of cement and effect of nano-silica (nS) fibers
with different percentages equal to 0.0, 1.0%, 2.0%, and 3.0% by
weight of cement on the cement mortar. The third and fourth groups
studied the effect of CNTs fiber with different percentage equal to
0.0%, 0.11%, and 0.22% by weight of cement, and effect of nS fibers
with different percentages were equal to 0.0%, 1.0%, and 2.0% by
weight of cement on the concrete. The compressive strength and
flexural strength at 7, 28, and 90 days is determined. From analysis of
tested results concluded that the nano-fibers is more effective when
used with cement mortar more than used with concrete because of
increasing the surface area, decreasing the pore and the collection of
nano-fibers. And also by adding nano-fibers the improvement of
flexural strength of concrete and cement mortar is more than
improvement of compressive strength.
Abstract: The current study investigated the influence of milling
time and ball-to-powder (BPR) weight ratio on the microstructural
constituents and mechanical properties of bulk nanocrystalline Al;
Al-10%Cu; and Al-10%Cu-5%Ti alloys. Powder consolidation was
carried out using a high frequency induction heat sintering where the
processed metal powders were sintered into a dense and strong bulk
material. The powders and the bulk samples were characterized using
XRD and FEGSEM techniques. The mechanical properties were
evaluated at various temperatures of 25°C, 100°C, 200°C, 300°C and
400°C to study the thermal stability of the processed alloys. The
processed bulk nanocrystalline alloys displayed extremely high
hardness values even at elevated temperatures. The Al-10%Cu-5%Ti
alloy displayed the highest hardness values at room and elevated
temperatures which are related to the presence of Ti-containing
phases such as Al3Ti and AlCu2Ti. These phases are thermally stable
and retain the high hardness values at elevated temperatures up to
400ºC.
Abstract: The present study was undertaken to investigate the
effect of pre-aging and aging parameters (time and temperature) on
the mechanical properties of Al-Mg-Zn (7075) alloys. Ultimate
tensile strength, 0.5% offset yield strength and % elongation
measurements were carried out on specimens prepared from cast and
heat treated 7075 alloys. Aging treatments were carried out for the as
solution treated (SHT) specimens (after quenching in warm water).
The specimens were aged at different conditions; Natural aging was
carried out at room temperature for different periods of time. Double
aging was performed for SHT conditions (pre-aged at different time
and temperature followed by high temperature aging). Ultimate
tensile strength, yield strength and % elongation as a function of
different pre-aging and aging parameters are analyzed to acquire an
understanding of the effects of these variables and their interactions
on the mechanical properties of Be-treated 7075 alloys.
Abstract: Vancron 40, a nitrided powder metallurgical tool
Steel, is used in cold work applications where the predominant failure
mechanisms are adhesive wear or galling. Typical applications of
Vancron 40 are among others fine blanking, cold extrusion, deep
drawing and cold work rolls for cluster mills. Vancron 40 positive
results for cold work rolls for cluster mills and as a tool for some
severe metal forming process makes it competitive compared to other
type of work rolls that require higher precision, among others in cold
rolling of thin stainless steel, which required high surface finish
quality. In this project, three roll materials for cold rolling of stainless
steel strip was examined, Vancron 40, Narva 12B (a high-carbon,
high-chromium tool steel alloyed with tungsten) and Supra 3 (a
Chromium-molybdenum tungsten-vanadium alloyed high speed
steel). The purpose of this project was to study the depth profiles of
the ironed stainless steel strips, emergence of galling and to study the
lubrication performance used by steel industries. Laboratory
experiments were conducted to examine scratch of the strip, galling
and surface roughness of the roll materials under severe tribological
conditions. The critical sliding length for onset of galling was
estimated for stainless steel with four different lubricants. Laboratory
experiments result of performance evaluation of resistance capability
of rolls toward adhesive wear under severe conditions for low and
high reductions. Vancron 40 in combination with cold rolling
lubricant gave good surface quality, prevents galling of
metal surfaces and good bearing capacity.
Abstract: Member States shall establish zones and
agglomerations throughout their territory to assess and manage air
quality in order to comply with European directives.
In Italy decree 155/2010, transposing Directive 2008/50/EC on
ambient air quality and cleaner air for Europe, merged into a single
act the previous provisions on ambient air quality assessment and
management, including those resulting from the implementation of
Directive 2004/107/EC relating to arsenic, cadmium, nickel, mercury
and polycyclic aromatic hydrocarbons in ambient air.
Decree 155/2010 introduced stricter rules for identifying zones on
the basis of the characteristics of the territory in spite of considering
pollution levels, as it was in the past. The implementation of such
new criteria has reduced the great variability of the previous zoning,
leading to a significant reduction of the total number of zones and to
a complete and uniform ambient air quality assessment and
management throughout the Country.
The present document is related to the new zones definition in
Italy according to Decree 155/2010. In particular the paper contains
the description and the analysis of the outcome of zoning and
classification.
Abstract: Building loss estimation methodologies which have
been advanced considerably in recent decades are usually used to
estimate socio and economic impacts resulting from seismic structural
damage. In accordance with these methods, this paper presents the
evaluation of an annual loss probability of a reinforced concrete
moment resisting frame designed according to Korean Building Code.
The annual loss probability is defined by (1) a fragility curve obtained
from a capacity spectrum method which is similar to a method adopted
from HAZUS, and (2) a seismic hazard curve derived from annual
frequencies of exceedance per peak ground acceleration. Seismic
fragilities are computed to calculate the annual loss probability of a
certain structure using functions depending on structural capacity,
seismic demand, structural response and the probability of exceeding
damage state thresholds. This study carried out a nonlinear static
analysis to obtain the capacity of a RC moment resisting frame
selected as a prototype building. The analysis results show that the
probability of being extensive structural damage in the prototype
building is expected to 0.01% in a year.
Abstract: It has experimentally been proved that the
performance of compression ignition (C.I.) engine is spray
characteristics related. In modern diesel engine the spray formation
and the eventual combustion process are the vital processes that offer
more challenges towards enhancing the engine performance. In the
present work the numerical simulation has been carried out for
evaporating diesel sprays using Fluent software. For computational
fluid dynamics simulation “Meshing” is done using Gambit software
before transmitting it into Fluent. The simulation is carried out using
hot bomb conditions under varying chamber conditions such as gas
pressure, nozzle diameter and fuel injection pressure. For comparison
purpose, the numerical simulations the chamber conditions were kept
the same as that of the experimental data. At varying chamber
conditions the spray penetration rates are compared with the existing
experimental results.
Abstract: The prepreg process among the CFRP (Carbon Fiber
Reinforced Plastic) forming methods is the short term of
‘Pre-impregnation’, which is widely used for aerospace composites
that require a high quality property such as a fiber-reinforced woven
fabric, in which an epoxy hardening resin is impregnated the reality.
However, that this process requires continuous researches and
developments for its commercialization because the delamination
characteristically develops between the layers when a great weight is
loaded from outside to supplement such demerit, three lamination
methods among the prepreg lamination methods of CFRP were
designed to minimize the delamination between the layers due to
external impacts. Further, the newly designed methods and the
existing lamination methods were analyzed through a mechanical
characteristic test, Interlaminar Shear Strength test. The Interlaminar
Shear Strength test result confirmed that the newly proposed three
lamination methods, i.e. the Roll, Half and Zigzag laminations,
presented more excellent strengths compared to the conventional Ply
lamination. The interlaminar shear strength in the roll method with
relatively dense fiber distribution was approximately 1.75% higher
than that in the existing ply lamination method, and in the half method,
it was approximately 0.78% higher.
Abstract: In this paper, the electromagnetic shielding
characteristics of an up-to-date typical carbon filler material, carbon
fiber used with a metal mesh were investigated. Carbon fiber
12k-prepregs, where carbon fibers were impregnated with epoxy, were
laminated with wire meshes, vacuum bag-molded and hardened to
manufacture hybrid-type specimens, with which an electromagnetic
shield test was performed in accordance with ASTM D4935-10,
through which was known as the most excellent reproducibility is
obtainable among electromagnetic shield tests. In addition, glass fiber
prepregs whose electromagnetic shielding effect were known as
insignificant were laminated and formed with wire meshes to verify
the validity of the electromagnetic shield effect of wire meshes in
order to confirm the electromagnetic shielding effect of metal meshes
corresponding existing carbon fiber 12k-prepregs. By grafting carbon
fibers, on which studies are being actively underway in the
environmental aspects and electromagnetic shielding effect, with
hybrid-type wire meshes that were analysed through the tests, in this
study, the applicability and possibility are proposed.