Abstract: Mycophenolic acid “MPA" is a secondary metabolite
of Penicillium bervicompactum with antibiotic and
immunosuppressive properties. In this study, fermentation process
was established for production of mycophenolic acid by Penicillium
bervicompactum MUCL 19011 in shake flask. The maximum MPA
production, product yield and productivity were 1.379 g/L, 18.6 mg/g
glucose and 4.9 mg/L.h respectively. Glucose consumption, biomass
and MPA production profiles were investigated during fermentation
time. It was found that MPA production starts approximately after
180 hours and reaches to a maximum at 280 h. In the next step, the
effects of methionine and acetate concentrations on MPA production
were evaluated. Maximum MPA production, product yield and
productivity (1.763 g/L, 23.8 mg/g glucose and 6.30 mg/L. h
respectively) were obtained with using 2.5 g/L methionine in culture
medium. Further addition of methionine had not more positive effect
on MPA production. Finally, results showed that the addition of
acetate to the culture medium had not any observable effect on MPA
production
Abstract: Temperature rise in a transformer depends on variety
of parameters such as ambient temperature, output current and type
of the core. Considering these parameters, temperature rise estimation
is still complicated procedure. In this paper, we present a new model
based on simple electrical equivalent circuit. This method avoids the
complication associated to accurate estimation and is in very good
agreement with practice.
Abstract: This paper presents the experimental results of silicone rubber polymer insulators for 22 kV systems under salt water dip wheel test based on IEC 62217. Straight shed silicone rubber polymer insulators having leakage distance 685 mm were tested continuously 30,000 cycles. One test cycle includes 4 positions, energized, de-energized, salt water dip and deenergized, respectively. For one test cycle, each test specimen remains stationary for about 40 second in each position and takes 8 second for rotate to next position. By visual observation, sever surface erosion was observed on the trunk near the energized end of tested specimen. Puncture was observed on the upper shed near the energized end. In addition, decreasing in hydrophobicity and increasing in hardness were measured on tested specimen comparing with new specimen. Furthermore, chemical analysis by ATR-FTIR was conducted in order to elucidate the chemical change of tested specimens comparing with new specimen.
Abstract: The evaluation of residual reliability of large sized
parallel computer interconnection systems is not practicable with
the existing methods. Under such conditions, one must go for
approximation techniques which provide the upper bound and lower
bound on this reliability. In this context, a new approximation method
for providing bounds on residual reliability is proposed here. The
proposed method is well supported by two algorithms for simulation
purpose. The bounds on residual reliability of three different categories
of interconnection topologies are efficiently found by using
the proposed method
Abstract: In an assessment of the extractability of metals in
green liquor dregs from the chemical recovery circuit of semichemical
pulp mill, extractable concentrations of heavy metals in
artificial gastric fluid were between 10 (Ni) and 717 (Zn) times
higher than those in artificial sweat fluid. Only Al (6.7 mg/kg; d.w.),
Ni (1.2 mg/kg; d.w.) and Zn (1.8 mg/kg; d.w.) showed extractability
in the artificial sweat fluid, whereas Al (730 mg/kg; d.w.), Ba (770
mg/kg; d.w.) and Zn (1290 mg/kg; d.w.) showed clear extractability
in the artificial gastric fluid. As certain heavy metals were clearly
soluble in the artificial gastric fluid, the careful handling of this
residue is recommended in order to prevent the penetration of green
liquor dregs across the human gastrointestinal tract.
Abstract: The main aim of this research is to study the possible
use of recycled fine aggregate made from waste rubble wall to
substitute partially for the natural sand used in the production of
cement and sand bricks. The bricks specimens were prepared by
using 100% natural sand; they were then replaced by recycled fine
aggregate at 25, 50, 75, and 100% by weight of natural sand. A series
of tests was carried out to study the effect of using recycled aggregate
on the physical and mechanical properties of bricks, such as density,
drying shrinkage, water absorption characteristic, compressive and
flexural strength. Test results indicate that it is possible to
manufacture bricks containing recycled fine aggregate with good
characteristics that are similar in physical and mechanical properties
to those of bricks with natural aggregate, provided that the percentage
of recycled fine aggregates is limited up to 50-75%.
Abstract: This paper aims to discuss the influence of resistance
characteristic on the high conductive concrete considering the changes
of voltage and environment. The high conductive concrete with
appropriate proportion is produced to the press-electrode method. The
curve of resistivity with the changes of voltage and environment is
plotted and the changes of resistivity are explored.
Abstract: Basic objective of this study is to create a regression
analysis method that can estimate the length of a plastic hinge which
is an important design parameter, by making use of the outcomes of
(lateral load-lateral displacement hysteretic curves) the experimental
studies conducted for the reinforced square concrete columns. For
this aim, 170 different square reinforced concrete column tests results
have been collected from the existing literature. The parameters
which are thought affecting the plastic hinge length such as crosssection
properties, features of material used, axial loading level,
confinement of the column, longitudinal reinforcement bars in the
columns etc. have been obtained from these 170 different square
reinforced concrete column tests. In the study, when determining the
length of plastic hinge, using the experimental test results, a
regression analysis have been separately tested and compared with
each other. In addition, the outcome of mentioned methods on
determination of plastic hinge length of the reinforced concrete
columns has been compared to other methods available in the
literature.
Abstract: Population diversification phenomena becomes quite common in villages located in China’s developed coastal area. Based on the analysis of the traditional rural society and its landscape characteristics, and in consideration of diversified landscape requirements due to the population diversification, with dual ideas of heritage and innovation, methods for rural landscape design were explored by taking Duxuao Village in Zhejiang Province of China as an example.
Abstract: We have developed a microfluidic device system for the continuous producting of nanoparticles, and we have clarified the relationship between the mixing performance of reactors and the particle size. First, we evaluated the mixing performance of reactors by carring out the Villermaux–Dushman reaction and determined the experimental conditions for producing AgCl nanoparticles. Next, we produced AgCl nanoparticles and evaluated the mixing performance and the particle size. We found that as the mixing performance improves the size of produced particles decreases and the particle size distribution becomes sharper. We produced AgCl nanoparticles with a size of 86 nm using the microfluidic device that had the best mixing performance among the three reactors we tested in this study; the coefficient of variation (Cv) of the size distribution of the produced nanoparticles was 26.1%.
Abstract: A new concept for long-term reagent storage for Labon- a-Chip (LoC) devices is described. Here we present a polymer multilayer stack with integrated stick packs for long-term storage of several liquid reagents, which are necessary for many diagnostic applications. Stick packs are widely used in packaging industry for storing solids and liquids for long time. The storage concept fulfills two main requirements: First, a long-term storage of reagents in stick packs without significant losses and interaction with surroundings, second, on demand releasing of liquids, which is realized by pushing a membrane against the stick pack through pneumatic pressure. This concept enables long-term on-chip storage of liquid reagents at room temperature and allows an easy implementation in different LoC devices.
Abstract: The purpose of research was to know the role of
immunogenic protein of 49 kDa from V.alginolyticus which capable
to initiate molecule expression of MHC Class II in receptor of
Cromileptes altivelis. The method used was in vivo experimental
research through testing of immunogenic protein 49 kDa from
V.alginolyticus at Cromileptes altivelis (size of 250 - 300 grams)
using 3 times booster by injecting an immunogenic protein in a
intramuscular manner. Response of expressed MHC molecule was
shown using immunocytochemistry method and SEM. Results
indicated that adhesin V.alginolyticus 49 kDa which have
immunogenic character could trigger expression of MHC class II on
receptor of grouper and has been proven by staining using
immunocytochemistry and SEM with labeling using antibody anti
MHC (anti mouse). This visible expression based on binding between
epitopes antigen and antibody anti MHC in the receptor. Using
immunocytochemistry, intracellular response of MHC to in vivo
induction of immunogenic adhesin from V.alginolyticus was shown.
Abstract: If price and quantity are the fundamental building
blocks of any theory of market interactions, the importance of trading
volume in understanding the behavior of financial markets is clear.
However, while many economic models of financial markets have
been developed to explain the behavior of prices -predictability,
variability, and information content- far less attention has been
devoted to explaining the behavior of trading volume. In this article,
we hope to expand our understanding of trading volume by
developing a new measure of herding behavior based on a cross
sectional dispersion of volumes betas. We apply our measure to the
Toronto stock exchange using monthly data from January 2000 to
December 2002. Our findings show that the herd phenomenon
consists of three essential components: stationary herding, intentional
herding and the feedback herding.
Abstract: Analytical expression for maximum power transfer
through a transmission line limited by voltage stability has been
formulated using exact representation of transmission line with
ABCD parameters. The expression has been used for plotting PV
curve at different power factors of a radial transmission line.
Limiting values of reactive power have been obtained.
Abstract: In this paper, we propose an algorithm to compute
initial cluster centers for K-means clustering. Data in a cell is
partitioned using a cutting plane that divides cell in two smaller cells.
The plane is perpendicular to the data axis with the highest variance
and is designed to reduce the sum squared errors of the two cells as
much as possible, while at the same time keep the two cells far apart
as possible. Cells are partitioned one at a time until the number of
cells equals to the predefined number of clusters, K. The centers of
the K cells become the initial cluster centers for K-means. The
experimental results suggest that the proposed algorithm is effective,
converge to better clustering results than those of the random
initialization method. The research also indicated the proposed
algorithm would greatly improve the likelihood of every cluster
containing some data in it.
Abstract: Given the motivation of maps impact in enhancing the
perception of the quality of life in a region, this work examines the
use of spatial analytical techniques in exploring the role of space in
shaping human development patterns in Assiut governorate.
Variations of human development index (HDI) of the governorate-s
villages, districts and cities are mapped using geographic information
systems (GIS). Global and local spatial autocorrelation measures are
employed to assess the levels of spatial dependency in the data and to
map clusters of human development. Results show prominent
disparities in HDI between regions of Assiut. Strong patterns of
spatial association were found proving the presence of clusters on the
distribution of HDI. Finally, the study indicates several "hot-spots" in
the governorate to be area of more investigations to explore the
attributes of such levels of human development. This is very
important for accomplishing the development plan of poorest regions
currently adopted in Egypt.
Abstract: In most of the cases, natural disasters lead to the
necessity of evacuating people. The quality of evacuation
management is dramatically improved by the use of information
provided by decision support systems, which become indispensable
in case of large scale evacuation operations. This paper presents a
best practice case study. In November 2007, officers from the
Emergency Situations Inspectorate “Crisana" of Bihor County from
Romania participated to a cross-border evacuation exercise, when
700 people have been evacuated from Netherlands to Belgium. One
of the main objectives of the exercise was the test of four different
decision support systems. Afterwards, based on that experience,
software system called TEVAC (Trans Border Evacuation) has been
developed “in house" by the experts of this institution. This original
software system was successfully tested in September 2008, during
the deployment of the international exercise EU-HUROMEX 2008,
the scenario involving real evacuation of 200 persons from Hungary
to Romania. Based on the lessons learned and results, starting from
April 2009, the TEVAC software is used by all Emergency
Situations Inspectorates all over Romania.
Abstract: In the present study, a heterogeneous and
homogeneous gas flow dispersion model for simulation and
optimisation of a large-scale catalytic slurry reactor for the direct
synthesis of dimethyl ether (DME) from syngas and CO2, using a
churn-turbulent regime was developed. In the heterogeneous gas flow
model the gas phase was distributed into two bubble phases: small
and large, however in the homogeneous one, the gas phase was
distributed into only one large bubble phase. The results indicated
that the heterogeneous gas flow model was in more agreement with
experimental pilot plant data than the homogeneous one.
Abstract: A major requirement for Grid application developers is ensuring performance and scalability of their applications. Predicting the performance of an application demands understanding its specific features. This paper discusses performance modeling and prediction of multi-agent based simulation (MABS) applications on the Grid. An experiment conducted using a synthetic MABS workload explains the key features to be included in the performance model. The results obtained from the experiment show that the prediction model developed for the synthetic workload can be used as a guideline to understand to estimate the performance characteristics of real world simulation applications.