Abstract: This work studied the ability of adipose tissue-derived
mesenchymal stromal cells (MSCs) to form stroma for expansion of
cord blood hematopoietic cells. We showed that 72-hour interaction
of MSCs with cord blood mononuclear cells (MNCs) in vitro at
atmospheric (20%) and low (5%) O2 conditions increased the
expression of ICAM-1, HCAM (at the beginning of interaction) on
MSCs. Viability of MSCs and MNCs were maintained at high level.
Adhesion of MNCs to MSCs was faster at 20% O2. MSCs promoted
the proliferation of adhered MNCs to form the suspension containing
great number of hematopoietic colony-forming units, and this effect
was more pronounced at 5% O2. Thus, adipose-derived MSCs
supplied sufficient stromal support to cord blood MNCs both at 20%
and 5% О2, providing their adhesion with further expansion of new
generation of different hematopoietic lineages.
Abstract: Amyloid aggregation of polypeptides is related to a
growing number of pathologic states known as amyloid disorders. In
recent years, blocking or reversing amyloid aggregation via the use of
small compounds are considered as two useful approaches in
hampering the development of these diseases. In this research, we
have compared the ability of several manganese-salen derivatives, as
synthetic compounds, and apigenin, as a natural flavonoid, to inhibit
of hen egg-white lysozyme (HEWL) aggregation, as an in vitro
model system.
Different spectroscopic analyses such as Thioflavin T (ThT) and
Anilinonaphthalene-8-sulfonic acid (ANS) fluorescence, Congo red
(CR) absorbance along with transmission electron microscopy were
used in this work to monitor the HEWL aggregation kinetic and
inhibition. Our results demonstrated that both type of compounds
were capable to prevent the formation of lysozyme amyloid
aggregation in vitro. In addition, our data indicated that synthetic
compounds had higher activity to inhibit of the β-sheet structures
relative to natural compound. Regarding the higher antioxidant
activities of the salen derivatives, it can be concluded that in addition
to aromatic rings of each of the compounds, the potent antioxidant
properties of salen derivatives contributes to lower lysozyme fibril
accumulation.
Abstract: The present environmental issues have made aircraft jet noise reduction a crucial problem in aero-acoustics research. Acoustic studies reveal that addition of chevrons to the nozzle reduces the sound pressure level reasonably with acceptable reduction in performance. In this paper comprehensive numerical studies on acoustic characteristics of different types of chevron nozzles have been carried out with non-reacting flows for the shape optimization of chevrons in supersonic nozzles for aerospace applications. The numerical studies have been carried out using a validated steady 3D density based, k-ε turbulence model. In this paper chevron with sharp edge, flat edge, round edge and U-type edge are selected for the jet acoustic characterization of supersonic nozzles. We observed that compared to the base model a case with round-shaped chevron nozzle could reduce 4.13% acoustic level with 0.6% thrust loss. We concluded that the prudent selection of the chevron shape will enable an appreciable reduction of the aircraft jet noise without compromising its overall performance. It is evident from the present numerical simulations that k-ε model can predict reasonably well the acoustic level of chevron supersonic nozzles for its shape optimization.
Abstract: This research aimed to produce offset printing inks from Samut Songkram’s coconut oil and to test properties of the printing inks comparing with commercial offset printing inks. One of the ingredients in the process of mixing varnish is coconut oil – used to produce black offset printing inks which were the subject of testing issues in order to compare with commercial offset printing inks. Based on the results of research, the best formula for mixing varnish was 50% of coconut oil, 36% of phenolic resin, and 14% of solvent oil. At the same time, the best formula in producing black offset inks was mixing varnish with 20% of coconut oil 20%. Consequently, the result of testing of properties of coconut oil based solvent offset printing inks regarding viscosity, tack and ink flow, showed that offset printing inks with oil based solvent had the properties less than commercial offset printing ink. Additionally, the result of testing also indicate that the rate of properties in aspects of ink spread and setting time of coconut oil based solvent offset printing were higher than that of commercial offset printing inks.
Abstract: Soy protein is a common ingredient added to processed meats to enhance its functional characteristics. In our study, soybean products (fermented soy Natto and protein hydrolysate) containing hydrolyzed peptides and amino acids, with or without ascorbic acid were added to burger in order to improve its quality characteristics. Results showed that soy additives significantly increased moisture and protein content and reduced (P < 0.05) fat values. Ash content did not affect with Natto additive. Color tools, lightness and yellowness were higher (P
Abstract: When it comes to last, it is regarded as the critical foundation of shoe design and development. Not only the last relates to the comfort of shoes wearing but also it aids the production of shoe styling and manufacturing. In order to enhance the efficiency and application of last development, a computer aided methodology for customized last form designs is proposed in this study. The reverse engineering is mainly applied to the process of scanning for the last form. Then the minimum energy is used for the revision of surface continuity, the surface of the last is reconstructed with the feature curves of the scanned last. When the surface of a last is reconstructed, based on the foundation of the proposed last form reconstruction module, the weighted arithmetic mean method is applied to the calculation on the shape morphing which differs from the grading for the control mesh of last, and the algorithm of subdivision is used to create the surface of last mesh, thus the feet-fitting 3D last form of different sizes is generated from its original form feature with functions remained. Finally, the practicability of the proposed methodology is verified through later case studies.
Abstract: The most important problem occurs on oil spills in sea
water is to reduce the oil spills size. This study deals with the
development of high pressurized nozzle using dispersion method for
oil leakage in offshore. 3D numerical simulation results were
obtained using ANSYS Fluent 13.0 code and correlate with the
experimental data for validation. This paper studies the contribution
of the process on flow speed and pressure of the flow from two
different geometrical designs of nozzles and to generate a spray
pattern suitable for dispersant application. Factor of size distribution
of droplets generated by the nozzle is calculated using pressures
ranging from 2 to 6 bars. Results obtain from both analyses shows a
significant spray pattern and flow distribution as well as distance.
Results also show a significant contribution on the effect of oil
leakage in terms of the diameter of the oil spills break up.
Abstract: Heat transfer from flat tube is studied numerically. Reynolds number is defined base on equivalent circular tube which is varied in range of 100 to 300. In these range of Reynolds number flow is considered to be laminar, unsteady, and incompressible. Equations are solved by using finite volume method. Results show that increasing l/D from 1 to 2 has insignificant effect on heat transfer and Nusselt number of flat tube is slightly lower than circular tube. However, thermal-hydraulic performance of flat tube is up to 2.7 times greater than circular tube.
Abstract: Metal matrix composites (MMCs) have gained a
considerable interest in the last three decades. Conventional powder
metallurgy production route often involves the addition of reinforcing
phases into the metal matrix directly, which leads to poor wetting
behavior between ceramic phase and metal matrix and the
segregation of reinforcements. The commonly used elements for
ceramic phase formation in iron based MMCs are Ti, Nb, Mo, W, V
and C, B. The aim of the present paper is to investigate the effect of
sintering temperature and V-B addition on densification, phase
development, microstructure, and hardness of Fe–V-B composites
(Fe-(5-10) wt. %B – 25 wt. %V alloys) prepared by powder
metallurgy process. Metal powder mixes were pressed uniaxial and
sintered at different temperatures (ranging from 1300 to 1400ºC) for
1h. The microstructure of the (V, B) Fe composites was studied with
the help of high magnification optical microscope and XRD.
Experimental results show that (V, B) Fe composites can be produced
by conventional powder metallurgy route.
Abstract: Mostly of public financing programs at national and regional level are funded from European Union sources. EU can participate directly to a national and regional program (example LEADER initiative, URBAN…) or indirectly by funding regional or national funds.Funds from European Union are provided from EU multiannual financial framework form which the annual budget is programmed. The adjusted program 2007-2013 of the EU considered commitments of almost 1 trillion Euros for the EU-28 countries. Provisions of the new program 2014-2020 consider commitments of more than 1 trillion Euros. Sustainable growth, divided to Cohesion and Competitiveness for Growth an Employment, is one of the two principal categories; the other is the preservation and management of natural resources.Through this financing process SMEs benefited of EU and public sources by receiving grants for their investments. Most of the financial instruments are available indirectly through the national financial intermediaries. Part of them is managed by the European Investment Fund.The paper focuses on the public financing to SMEs by examining case studies on divers forms of public help. It tries to distinguish the efficiency of the examined good practices and therefore try to have some conclusions on the possibility of application to other regions.
Abstract: Vertical slotted walls can be used as permeable
breakwaters to provide economical and environmental protection
from undesirable waves and currents inside the port. The permeable
breakwaters are partially protection and have been suggested to
overcome the environmental disadvantages of fully protection
breakwaters. For regular waves a semi-analytical model is based on
an eigenfunction expansion method and utilizes a boundary condition
at the surface of each wall are developed to detect the energy
dissipation through the slots. Extensive laboratory tests are carried
out to validate the semi-analytic models. The structure of the physical
model contains two walls and it consists of impermeable upper and
lower part, where the draft is based a decimal multiple of the total
depth. The middle part is permeable with a porosity of 50%. The
second barrier is located at a distant of 0.5, 1, 1.5 and 2 times of the
water depth from the first one. A comparison of the theoretical results
with previous studies and experimental measurements of the present
study show a good agreement and that, the semi-analytical model is
able to adequately reproduce most the important features of the
experiment.
Abstract: Sustainable tall buildings that provide comfortable,
healthy and efficient indoor environments are clearly desirable as the
densification of living and working space for the world’s increasing
population proceeds. For environmental concerns, these buildings
must also be energy efficient. One component of these tasks is the
provision of indoor air quality and thermal comfort, which can be
enhanced with natural ventilation by the supply of fresh air. Working
spaces can only be naturally ventilated with connections to the
outdoors utilizing operable windows, double facades, ventilation
stacks, balconies, patios, terraces and skygardens. Large amounts of
fresh air can be provided to the indoor spaces without mechanical
air-conditioning systems, which are widely employed in
contemporary tall buildings.
This paper tends to present the concept of natural ventilation for
sustainable tall office buildings in order to achieve healthy and
comfortable working spaces, as well as energy efficient
environments. Initially the historical evolution of ventilation
strategies for tall buildings is presented, beginning with natural
ventilation and continuing with the introduction of mechanical airconditioning
systems. Then the emergence of natural ventilation due
to the health and environmental concerns in tall buildings is handled,
and the strategies for implementing this strategy are revealed. In the
next section, a number of case studies that utilize this strategy are
investigated. Finally, how tall office buildings can benefit from this
strategy is discussed.
Abstract: Information technology is changing rapidly and the users’ expectations are also growing. Dealing with these changes in information technology, while satisfying the users’ needs and expectations is a big challenge. IT managers need to explore new mechanisms/strategies to enable them to cope with such challenges.
The objectives of this research are to identify the significant challenges that might face IT managers in higher education institutes in the face of the high and ever growing customer expectations and to propose possible solutions to cope with such high-speed changes in information technology.
To achieve these objectives, interviews with the IT professionals from different higher education institutes in Oman were conducted. In addition, documentation (printed and online) related to these institutions were studied and an intensive literature review of published work was examined.
The findings of this research are expected to give a better understanding of the challenges that might face the IT managers at higher education institutes. This acquired understanding is expected to highlight the importance of being adaptable and fast in keeping up with the ever-growing technological changes. Moreover, adopting different tools and technologies could assist IT managers in developing their organisations’ IT policies and strategies.
Abstract: In the past, the most comprehensively adopted light
source was incandescent light bulbs, but with the appearance of LED
light sources, traditional light sources have been gradually replaced by
LEDs because of its numerous superior characteristics. However,
many of the standards do not apply to LEDs as the two light sources
are characterized differently. This also intensifies the significance of
studies on LEDs. As a Kansei design study investigating the visual
glare produced by traffic arrows implemented with LEDs, this study
conducted a semantic analysis on the styles of traffic arrows used in
domestic and international occasions. The results will be able to
reduce drivers’ misrecognition that results in the unsuccessful arrival
at the destination, or in traffic accidents. This study started with a
literature review and surveyed the status quo before conducting
experiments that were divided in two parts. The first part involved a
screening experiment of arrow samples, where cluster analysis was
conducted to choose five representative samples of LED displays. The
second part was a semantic experiment on the display of arrows using
LEDs, where the five representative samples and the selected ten
adjectives were incorporated. Analyzing the results with
Quantification Theory Type I, it was found that among the
composition of arrows, fletching was the most significant factor that
influenced the adjectives. In contrast, a “no fletching” design was
more abstract and vague. It lacked the ability to convey the intended
message and might bear psychological negative connotation including
“dangerous,” “forbidden,” and “unreliable.” The arrow design
consisting of “> shaped fletching” was found to be more concrete and
definite, showing positive connotation including “safe,” “cautious,”
and “reliable.” When a stimulus was placed at a farther distance, the
glare could be significantly reduced; moreover, the visual evaluation
scores would be higher. On the contrary, if the fletching and the shaft
had a similar proportion, looking at the stimuli caused higher
evaluation at a closer distance. The above results will be able to be
applied to the design of traffic arrows by conveying information
definitely and rapidly. In addition, drivers’ safety could be enhanced
by understanding the cause of glare and improving visual
recognizability.
Abstract: In this study, a liquid phase microextraction by hollow fiber (HF-LPME) combined with high performance liquid chromatography-UV detector was applied to preconcentrate and determine trace levels of Cyproheptadine in human urine and plasma samples. Cyproheptadine was extracted from 10 mL alkaline aqueous solution (pH: 9.81) into an organic solvent (n-octnol) which was immobilized in the wall pores of a hollow fiber. Then was back-extracted into an acidified aqueous solution (pH: 2.59) located inside the lumen of the hollow fiber. This method is simple, efficient and cost-effective. It is based on pH gradient and differences between two aqueous phases. In order to optimize the HF-LPME some affecting parameters including the pH of donor and acceptor phases, the type of organic solvent, ionic strength, stirring rate, extraction time and temperature were studied and optimized. Under optimal conditions enrichment factor, limit of detection (LOD) and relative standard deviation (RSD(%), n=3) were up to 112, 15 μg.L−1 and 2.7, respectively.
Abstract: Each of the countries around the world has different
ways of management and many of them depend on people to
administrate their country. Thailand, for example, empowers the
sovereignty of Thai people under constitution; however, our Thai
voting system is not able to flow fast enough under the current
Political management system. The sovereignty of Thai people is
addressing this problem through representatives during current
elections, in order to set a new policy for the countries ideology to
change in the House and the Cabinet.
This is particularly important in a democracy to be developed
under our current political institution. The Organic Act on Political
Parties 2007 is the establishment we have today that is causing
confrontations within the establishment. There are many political
parties that will soon be abolished. Many political parties have
already been subsidized. This research study is to analyze the legal
problems with the political party establishment under the Organic Act
on Political Parties 2007.
This will focus on the freedom of each political establishment
compared to an effective political operation. Textbooks and academic
papers will be referenced from studies home and abroad.
The study revealed that Organic Act on Political Parties 2007 has
strict provisions on the political structure over the number of
members and the number of branches involved within political
parties system.
Such operations shall be completed within one year; but under the
existing laws the small parties are not able to participate with the
bigger parties. The cities are capable of fulfilling small political party
requirements but fail to become coalesced because the current laws
won't allow them to be united as one. It is important to allow all
independent political parties to join our current political structure.
Board members can’t help the smaller parties to become a large
organization under the existing Thai laws.
Creating a new establishment that functions efficiently throughout
all branches would be one solution to these legal problems between
all political parties. With this new operation, individual political
parties can participate with the bigger parties during elections. Until
current political institutions change their system to accommodate
public opinion, these current Thai laws will continue to be a problem
with all political parties in Thailand.
Abstract: This paper conducts a comparison study using KES-FB and PhabrOmeter to measure 58 selected warp knitted fabric hand properties. Fabric samples were selected and measured by both KES-FB and PhabrOmeter. Results show differences between these two measurement methods. Smoothness and stiffness values obtained by KES-FB were found significant correlated (p value = 0.003 and 0.022) to the PhabrOmeter results while softness values between two measurement methods did not show significant correlation (p value = 0.828). Disagreements among these two measurement methods imply limitations on different mechanism principles when facing warp knitted fabrics. Subjective measurement methods and further studies are suggested in order to ascertain deeper investigation on the mechanisms of fabric hand perceptions.
Abstract: Microwave dielectric ceramic materials of
(Mg1-xNix)2(Ti0.95Sn0.05)O4 for x = 0.01, 0.03, 0.05, 0.07 and 0.09 were
prepared and sintered at 1250–1400 ºC. The microstructure and
microwave dielectric properties of the ceramic materials were
examined and measured. The observations shows that the content of
Ni2+ ions has little effect on the crystal structure, dielectric constant,
temperature coefficient of resonant frequency (τf) and sintering
temperatures of the ceramics. However, the quality values (Q×f) are
greatly improved due to the addition of Ni2+ ions. The present study
showed that the ceramic material prepared for x = 0.05 and sintered at
1325ºC had the best Q×f value of 392,000 GHz, about 23%
improvement compared with that of Mg2(Ti0.95Sn0.05)O4.
Abstract: The sound pressure level (SPL) of the moving-coil
loudspeaker (MCL) is often simulated and analyzed using the lumped
parameter model. However, the SPL of a MCL cannot be simulated
precisely in the high frequency region, because the value of cone
effective area is changed due to the geometry variation in different
mode shapes, it is also related to affect the acoustic radiation mass and
resistance. Herein, the paper presents the inverse method which has a
high ability to measure the value of cone effective area in various
frequency points, also can estimate the MCL electroacoustic
parameters simultaneously. The proposed inverse method comprises
the direct problem, adjoint problem, and sensitivity problem in
collaboration with nonlinear conjugate gradient method. Estimated
values from the inverse method are validated experimentally which
compared with the measured SPL curve result. Results presented in
this paper not only improve the accuracy of lumped parameter model
but also provide the valuable information on loudspeaker cone design.
Abstract: Sustainable urban waterfront development is one of the
most interesting phenomena of urban renewal in the last decades.
However, there are still many cities whose visual image is
compromised due to the lack of a sustainable urban waterfront
development, which consequently affects the place of those cities
globally. This paper aims to reimagine the role of waterfront areas in
city design, with a particular focus on Egypt, so that they provide
attractive, sustainable urban environments while promoting the
continued aesthetic development of the city overall. This aim will be
achieved by determining the main principles of a sustainable urban
waterfront and its applications. This paper concentrates on
sustainability assessment rating systems. A number of international
case-studies, wherein a city has applied the basic principles for a
sustainable urban waterfront and have made use of sustainability
assessment rating systems, have been selected as examples which can
be applied to the urban waterfronts in Egypt. This paper establishes the
importance of developing the design of urban environments in Egypt,
as well as identifying the methods of sustainability application for
urban waterfronts.