Abstract: Every 2-3 years the influenza B virus serves
epidemics. Neuraminidase (NA) is an important target for influenza
drug design. Although, oseltamivir, an oral neuraminidase drug, has
been shown good inhibitory efficiency against wild-type of influenza
B virus, the lower susceptibility to the R152K mutation has been
reported. Better understanding of oseltamivir efficiency and
resistance toward the influenza B NA wild-type and R152K mutant,
respectively, could be useful for rational drug design. Here, two
complex systems of wild-type and R152K NAs with oseltamivir
bound were studied using molecular dynamics (MD) simulations.
Based on 5-ns MD simulation, the loss of notable hydrogen bond and
decrease in per-residue decomposition energy from the mutated
residue K152 contributed to drug compared to those of R152 in wildtype
were found to be a primary source of high-level of oseltamivir
resistance due to the R152K mutation.
Abstract: This paper present a circular patch microstrip array antenna operate in KU-band (10.9GHz – 17.25GHz). The proposed circular patch array antenna will be in light weight, flexible, slim and compact unit compare with current antenna used in KU-band. The paper also presents the detail steps of designing the circular patch microstrip array antenna. An Advance Design System (ADS) software is used to compute the gain, power, radiation pattern, and S11 of the antenna. The proposed Circular patch microstrip array antenna basically is a phased array consisting of 'n' elements (circular patch antennas) arranged in a rectangular grid. The size of each element is determined by the operating frequency. The incident wave from satellite arrives at the plane of the antenna with equal phase across the surface of the array. Each 'n' element receives a small amount of power in phase with the others. There are feed network connects each element to the microstrip lines with an equal length, thus the signals reaching the circular patches are all combined in phase and the voltages add up. The significant difference of the circular patch array antenna is not come in the phase across the surface but in the magnitude distribution.
Abstract: Residual dye contents in textile dyeing wastewater have complex aromatic structures that are resistant to degrade in biological wastewater treatment. The objectives of this study were to determine the effectiveness of nanoscale zerovalent iron (NZVI) to decolorize Reactive Black 5 (RB5) and Reactive Red 198 (RR198) in synthesized wastewater and to investigate the effects of the iron particle size, iron dosage and solution pHs on the destruction of RB5 and RR198. Synthesized NZVI was confirmed by transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). The removal kinetic rates (kobs) of RB5 (0.0109 min-1) and RR198 (0.0111 min-1) by 0.5% NZVI were many times higher than those of microscale zerovalent iron (ZVI) (0.0007 min-1 and 0.0008 min-1, respectively). The iron dosage increment exponentially increased the removal efficiencies of both RB5 and RR198. Additionally, lowering pH from 9 to 5 increased the decolorization kinetic rates of both RB5 and RR198 by NZVI. The destruction of azo bond (N=N) in the chromophore of both reactive dyes led to decolorization of dye solutions.
Abstract: The main objective of our study is to collect data
about the profile of the asthmatic patients in Assam and thereby have
a comprehensive knowledge of the factors influencing the asthmatic
patients of the state and their medication pattern. We developed a
search strategy to find any publication about the community based
survey asthma related and used. These to search the MEDLINE
(1996 to current literature) CINAHL DOAJ pubmed databases using
the key phrases, Asthma, Respiratory disorders, Drug therapy of
Asthma, database decision support system and asthma. The
appropriate literature was printed out from the online source and
library (Journal) source. The study was conducted through a set of
structured and non-structured questionnaires targeted on the
asthmatic patients belonging to the rural and urban areas of Assam,
during the month of Dec 2006 to July 2007, 138 cases were studied
in Gauwathi Medical College & Hospital located in Bhangagarh,
Assam in India. The demographic characteristics a factor in 138
patients with asthma with allergic rhinitis (cases) gives the detail
profile of asthmatic patient-s distribution of Assam as classified on
the basis of age and sex. It is evident from the study that male
populations (66%) are more prone to asthma as compared to the
females (34%).Another striking features that emerged from this
survey is the maximum prevalence of asthma in the age group of 20-
30 years followed by infants belonging to the age group of 7 (0.05%)
0-10years among both male and female populations of Assam. The
high incidence of asthma in the age group of 20-30 years may
probably be due to the allergy arising out of sudden exposure to dust
and pollen which the children face while playing and going to the
school. The rural females in the age group of 30-40 years are more
prone to asthma than urban females in the same age group may be
due to sex differentiation among the tribal population of the state.
Pharmacists should educate the asthmatics how to use inhalers
considering growing menace of asthma in the state. Safer drugs
should be produced in the form of aerosol so that easy administration
by the asthmatic patients and physicians of the state is possible for
curing asthma. The health centers should be more equipped with the
medicines to cure asthma in the state like Assam.
Abstract: Copolymerization of ethylene with 1-hexene was
carried out using two ansa-fluorenyl titanium derivative complexes.
The substituent effect on the catalytic activity, monomer reactivity
ratio and polymer property was investigated. It was found that the
presence of t-Bu groups on fluorenyl ring exhibited remarkable
catalytic activity and produced polymer with high molecular weight.
However, these catalysts produce polymer with narrow molecular
weight distribution, indicating the characteristic of single-site
metallocene catalyst. Based on 13C NMR, we can observe that
monomer reactivity ratio was affected by catalyst structure. The rH
values of complex 2 were lower than that of complex 1 which might
be result from the higher steric hindrance leading to a reduction of 1-
hexene insertion step.
Abstract: In this paper, determining the optimal proportionalintegral-
derivative (PID) controller gains of an single-area load
frequency control (LFC) system using genetic algorithm (GA) is
presented. The LFC is notoriously difficult to control optimally using
conventionally tuning a PID controller because the system parameters
are constantly changing. It is for this reason the GA as tuning strategy
was applied. The simulation has been conducted in MATLAB
Simulink package for single area power system. the simulation results
shows the effectiveness performance of under various disturbance.
Abstract: The commercial finite element program LS-DYNA was employed to evaluate the response and energy absorbing capacity of cylindrical metal tubes that are externally wrapped with composite. The effects of composite wall thickness, loading conditions and fiber ply orientation were examined. The results demonstrate that a wrapped composite can be utilized effectively to enhance the crushing characteristics and energy absorbing capacity of the tubes. Increasing the thickness of the composite increases the mean force and the specific energy absorption under both static and dynamic crushing. The ply pattern affects the energy absorption capacity and the failure mode of the metal tube and the composite material property is also significant in determining energy absorption efficiency.
Abstract: This research was conducted in the Lower Namkam
Irrigation Project situated in the Namkam River Basin in Thailand.
Degradation of groundwater quality in some areas is caused by saline
soil spots beneath ground surface. However, the tail regulated gate
structure on the Namkam River, a lateral stream of the Mekong
River. It is aimed for maintaining water level in the river at +137.5 to
+138.5 m (MSL) and flow to the irrigation canals based on a gravity
system since July 2009. It might leach some saline soil spots from
underground to soil surface if lack of understanding of the
conjunctive surface water and groundwater behaviors. This research
has been conducted by continuously the observing of both shallow
and deep groundwater level and quality from existing observation
wells. The simulation of surface water was carried out using a
hydrologic modeling system (HEC-HMS) to compute the ungauged
side flow catchments as the lateral flows for the river system model
(HEC-RAS). The constant water levels in the upstream of the
operated gate caused a slight rising up of shallow groundwater level
when compared to the water table. However, the groundwater levels
in the confined aquifers remained less impacted than in the shallow
aquifers but groundwater levels in late of wet season in some wells
were higher than the phreatic surface. This causes salinization of the
groundwater at the soil surface and might affect some crops. This
research aims for the balance of water stage in the river and efficient
groundwater utilization in this area.
Abstract: The objective of this study is to examine the validity of Wagner-s law and relationship between economic growth, population and export for Pakistan. The ARDL Bounds cointegration and ECM are utilized for long and short run equilibrium for the period of 1972-2007. Population has considerable role in an economy and exports are the main source to raise the GDP. With the increase in GDP, the government expenditures may or may not increase. The empirical results indicate that the Wagner-s Law does hold, as economic growth is significantly and positively correlated with government expenditures. However, population and exports have also significant and positive impact on government expenditures both in short and long run. The significant and negative coefficient of error correction term in ECM indicates that after a shock, the long rum equilibrium will again converge towards equilibrium about 70.82 percent within a year.
Abstract: This work proposes an optical fiber system (OF) for
sensing various volatile organic compounds (VOCs) in human breath
for the diagnosis of some metabolic disorders as a non-invasive
methodology. The analyzed VOCs are alkanes (i.e., ethane, pentane,
heptane, octane, and decane), and aromatic compounds (i.e., benzene,
toluene, and styrene). The OF displays high analytical performance
since it provides near real-time responses, rapid analysis, and low
instrumentation costs, as well as it exhibits useful linear range and
detection limits; the developed OF sensor is also comparable to a
reference methodology (gas chromatography-mass spectrometry) for
the eight tested VOCs.
Abstract: This paper suggests ranking alternatives under fuzzy
MCDM (multiple criteria decision making) via an centroid based
ranking approach, where criteria are classified to benefit qualitative,
benefit quantitative and cost quantitative ones. The ratings of
alternatives versus qualitative criteria and the importance weights of
all criteria are assessed in linguistic values represented by fuzzy
numbers. The membership function for the final fuzzy evaluation
value of each alternative can be developed through α-cuts and
interval arithmetic of fuzzy numbers. The distance between the
original point and the relative centroid is applied to defuzzify the
final fuzzy evaluation values in order to rank alternatives. Finally a
numerical example demonstrates the computation procedure of the
proposed model.
Abstract: Parallel Prefix addition is a technique for improving
the speed of binary addition. Due to continuing integrating intensity
and the growing needs of portable devices, low-power and highperformance
designs are of prime importance. The classical parallel
prefix adder structures presented in the literature over the years
optimize for logic depth, area, fan-out and interconnect count of logic
circuits. In this paper, a new architecture for performing 8-bit, 16-bit
and 32-bit Parallel Prefix addition is proposed. The proposed prefix
adder structures is compared with several classical adders of same
bit width in terms of power, delay and number of computational
nodes. The results reveal that the proposed structures have the least
power delay product when compared with its peer existing Prefix
adder structures. Tanner EDA tool was used for simulating the adder
designs in the TSMC 180 nm and TSMC 130 nm technologies.
Abstract: The free and forced in-plane vibrations of axially
moving plates are investigated in this work. The plate possesses an
internal damping of which the constitutive relation obeys the
Kelvin-Voigt model, and the excitations are arbitrarily distributed on
two opposite edges. First, the equations of motion and the boundary
conditions of the axially moving plate are derived. Then, the extended
Ritz method is used to obtain discretized system equations. Finally,
numerical results for the natural frequencies and the mode shapes of
the in-plane vibration and the in-plane response of the moving plate
subjected to arbitrary edge excitations are presented. It is observed that
the symmetry class of the mode shapes of the in-plane vibration
disperses gradually as the moving speed gets higher, and the u- and
v-components of the mode shapes belong to different symmetry class.
In addition, large response amplitudes having shapes similar to the
mode shapes of the plate can be excited by the edge excitations at the
resonant frequencies and with the same symmetry class of distribution
as the u-components.
Abstract: There has been gradual progress of late in construction projects, particularly in big-scale megaprojects. Due to the long-term construction period, however, with large-scale budget investment, lack of construction management technologies, and increase in the incomplete elements of project schedule management, a plan to conduct efficient operations and to ensure business safety is required. In particular, as the project management information system (PMIS) is meant for managing a single project centering on the construction phase, there is a limitation in the management of program-scale businesses like megaprojects. Thus, a program management information system (PgMIS) that includes program-level management technologies is needed to manage multiple projects. In this study, a support tool was developed for managing the cost and schedule information occurring in the construction phase, at the program level. In addition, a case study on the developed support tool was conducted to verify the usability of the system. With the use of the developed support tool program, construction managers can monitor the progress of the entire project and of the individual subprojects in real time.
Abstract: A CFD software was employed to analyze the
characteristics of the flat round porous aerostatic bearings. The effects
of gap between the bearing and the guide way and the porosity of the
porous material on the load capacity of the bearing were studied. The
adequacy of the simulation model and the approach was verified. From
the parametric study, it is found that the depth of the flow path does not
influence the load capacity of the bearing; the load capacity of the
bearing will decrease if the thickness of the porous material increases
or the porous material protrudes above the bearing housing; the
variation of the chamfer at the edge of the bearing does not affect the
bearing load capacity. For a bearing with an air gap of 5μm and a
porosity of 0.1, the average load capacity and the pressure distribution
of the bearing are nearly unchanged no matter the bearing moves at a
constant or a varying speed.
Abstract: There are few studies on eggshell of leatherback turtle
which is endangered species in Thailand. This study was focusing on
the ultrastructure and elemental composition of leatherback turtle
eggshells collected from Andaman Sea Shore, Thailand during the
nesting season using scanning electron microscope (SEM). Three
eggshell layers of leatherback turtle; the outer cuticle layer or
calcareous layer, the middle layer or middle multistrata layer and the
inner fibrous layer were recognized. The outer calcareous layer was
thick and porosity which consisted of loose nodular units of various
crystal shapes and sizes. The loose attachment between these units
resulted in numerous spaces and openings. The middle layer was
compact thick with several multistrata and contained numerous
openings connecting to both outer cuticle layer and inner fibrous
layer. The inner fibrous layer was compact and thin, and composed of
numerous reticular fibers. Energy dispersive X-ray microanalysis
detector revealed energy spectrum of X-rays character emitted from
all elements on each layer. The percentages of all elements were
found in the following order: carbon (C) > oxygen (O) > calcium
(Ca) > sulfur (S) > potassium (K) > aluminum (Al) > iodine (I) >
silicon (Si) > chlorine (Cl) > sodium (Na) > fluorine (F) >
phosphorus (P) > magnesium (Mg). Each layer consisted of high
percentage of CaCO3 (approximately 98%) implying that it was
essential for turtle embryonic development. A significant difference
was found in the percentages of Ca and Mo in the 3layers. Moreover,
transition metal, metal and toxic non-metal contaminations were
found in leatherback turtle eggshell samples. These were palladium
(Pd), molybdenum (Mo), copper (Cu), aluminum (Al), lead (Pb), and
bromine (Br). The contamination elements were seen in the outer
layers except for Mo. All elements were readily observed and
mapped using Smiling program. X-ray images which mapped the
location of all elements were showed. Calcium containing in the
eggshell appeared in high contents and was widely distributing in
clusters of the outer cuticle layer to form CaCO3 structure. Moreover,
the accumulation of Na and Cl was observed to form NaCl which was
widely distributing in 3 eggshell layers. The results from this study
would be valuable on assessing the emergent success in this
endangered species.
Abstract: Semiconductor detector arrays are widely used in
high-temperature plasma diagnostics. They have a fast response,
which allows observation of many processes and instabilities in
tokamaks. In this paper, there are reviewed several diagnostics based
on semiconductor arrays as cameras, AXUV photodiodes (referred
often as fast “bolometers") and detectors of both soft X-rays and
visible light installed on the COMPASS tokamak recently. Fresh
results from both spring and summer campaigns in 2012 are
introduced. Examples of the utilization of the detectors are shown on
the plasma shape determination, fast calculation of the radiation
center, two-dimensional plasma radiation tomography in different
spectral ranges, observation of impurity inflow, and also on
investigation of MHD activity in the COMPASS tokamak discharges.
Abstract: The author present PID controller design for
following control of hard disk drive by characteristic ratio assignment
method. The study in this paper concerns design of a PID controller
which sufficiently robust to the disturbances and plant perturbations
on following control of hard disk drive. Characteristic Ratio
Assignment (CRA) is shown to be an efficient control technique to
serve this requirement. The controller design by CRA is based on the
choice of the coefficients of the characteristic polynomial of the
closed loop system according to the convenient performance criteria
such as equivalent time constant and ration of characteristic
coefficient. Hence, in this study, CRA method is applied in PID
controller design for following control of hard disk drive. Matlab
simulation results shown that CRA design is fairly stable and robust
whilst giving the convenience in controller-s parameters adjustment.
Abstract: A series of Ti based shape memory alloys with
composition of Ti50Ni49Cr1, Ti50Ni47Cr3 and Ti50Ni45Cr5 were
developed by vacuum arc-melting under a purified argon atmosphere.
The histometric and corrosion evaluation of Ti-Ni-Cr shape memory
alloys have been considered in this research work. The alloys were
developed by vacuum arc melting and implanted subcutaneously in
rabbits for 4, 8 and 12 weeks. Metallic implants were embedded in
order to determine the outcome of implantation on histometric and
corrosion evaluation of Ti-Ni-Cr metallic strips. Encapsulating
membrane formation around the alloys was minimal in the case of all
materials. After histomorphometric analyses it was possible to
demonstrate that there were no statistically significant differences
between the materials. Corrosion rate was also determined in this
study which is within acceptable range. The results showed the Ti-
Ni-Cr alloy was neither cytotoxic, nor have any systemic reaction on
living system in any of the test performed. Implantation shows good
compatibility and a potential of being used directly in vivo system.
Abstract: The nanofiber sheet of Multiwall Cabon Nanotube
(MWCNTs)/Polyacylonitile (PAN) composites was fabricated from
electrospun nanofiber. Firstly the surface of MWCNTs was
chemically modified, comparing two different techniques consisting
of admicellar polymerization and functionalization to improve the
dispersion and prevent the aggregation in the PAN matrix. The
modified MWCNTs were characterized by the dispersion in
dimethylformamide (DMF) solvent, Laser particle size, and FTRaman.
Lastly, DSC, SEM and mechanical properties of the
nanofiber sheet were examined. The results show that the mechanical
properties of the nanofiber sheet prepared from admicellar
polymerization-modified MWCNTs were higher than those of the
others.