Abstract: Today, cancer remains one of the major diseases that
lead to death. The main obstacle in chemotherapy as a main cancer
treatment is the toxicity to normal cells due to Multidrug Resistance
(MDR) after the use of anticancer drugs. Proposed solution to
overcome this problem is the use of MDR efflux inhibitor of cinchona
alkaloids which is delivered together with anticancer drugs
encapsulated in the form of polymeric nanoparticles. The particles
were prepared by the hydration method. The characterization of
nanoparticles was particle size, zeta potential, entrapment efficiency
and in vitro drug release. Combination nanoparticle size ranged 29-45
nm with a neutral surface charge. Entrapment efficiency was above
87% for the use quinine, quinidine or cinchonidine in combination
with etoposide. The release test results exhibited that the cinchona
alkaloids release released faster than that of etoposide. Collectively,
cinchona alkaloids can be packaged along with etoposide in
nanomicelles for better cancer therapy.
Abstract: In this paper, a nonlinear model predictive swing-up
and stabilizing sliding controller is proposed for an inverted
pendulum-cart system. In the swing up phase, the nonlinear model
predictive control is formulated as a nonlinear programming problem
with energy based objective function. By solving this problem at
each sampling instant, a sequence of control inputs that optimize the
nonlinear objective function subject to various constraints over a
finite horizon are obtained. Then, this control drives the pendulum to
a predefined neighborhood of the upper equilibrium point, at where
sliding mode based model predictive control is used to stabilize the
systems with the specified constraints. It is shown by the simulations
that, due to the way of formulating the problem, short horizon
lengths are sufficient for attaining the swing up goal.
Abstract: In today-s global and competitive market,
manufacturing companies are working hard towards improving their
production system performance. Most companies develop production
systems that can help in cost reduction. Manufacturing systems
consist of different elements including production methods,
machines, processes, control and information systems. Human issues
are an important part of manufacturing systems, yet most companies
do not pay sufficient attention to them. In this paper, a workforce
planning (WP) model is presented. A non-linear programming model
is developed in order to minimize the hiring, firing, training and
overtime costs. The purpose is to determine the number of workers
for each worker type, the number of workers trained, and the number
of overtime hours. Moreover, a decision support system (DSS) based
on the proposed model is introduced using the Excel-Lingo software
interfacing feature. This model will help to improve the interaction
between the workers, managers and the technical systems in
manufacturing.
Abstract: In the present work flow past circular cylinder and
cylinder with rectangular and triangular wake splitter is studied to
improve aerodynamic parameters. The Comparison of drag
coefficient is tabulated for bare cylinder, cylinder with rectangular
and triangular wake splitters. Flow past circular cylinder and cylinder
with triangular and rectangular wake splitter is performed at
Reynoldsnumber 5, 20, 40, 50,80, 100.An incompressible PISO finite
volume code employing a non-staggered grid arrangement is used, a
second order upwind scheme is used for convective terms. The time
discretization is implicit and a Second order Crank-Nicholson scheme
is employed. Length of wake splitter in both configurations is taken
to be equal to diameter of cylinder. Wake length is found to be less
with rectangular wake splitter when compared to bare cylinder and
cylinder with triangular wake splitter. Coefficient of drag is found to
be less for triangular wake splitter when compared to bare cylinder &
cylinder with rectangular wake splitter.
Abstract: Electrocardiogram (ECG) is considered to be the
backbone of cardiology. ECG is composed of P, QRS & T waves and
information related to cardiac diseases can be extracted from the
intervals and amplitudes of these waves. The first step in extracting
ECG features starts from the accurate detection of R peaks in the
QRS complex. We have developed a robust R wave detector using
wavelets. The wavelets used for detection are Daubechies and
Symmetric. The method does not require any preprocessing therefore,
only needs the ECG correct recordings while implementing the
detection. The database has been collected from MIT-BIH arrhythmia
database and the signals from Lead-II have been analyzed. MatLab
7.0 has been used to develop the algorithm. The ECG signal under
test has been decomposed to the required level using the selected
wavelet and the selection of detail coefficient d4 has been done based
on energy, frequency and cross-correlation analysis of decomposition
structure of ECG signal. The robustness of the method is apparent
from the obtained results.
Abstract: This study presents the performance of membrane
bioreactor in treating high phosphate wastewater. The laboratory
scale MBR was operated at permeate flux of 25 L/m2.h with a hollow
fiber membrane (polypropylene, approx. pore size 0.01 - 0.2 μm) at
hydraulic retention time (HRT) of 12 hrs. Scanning electron
microscopy (SEM) and energy diffusive X-ray (EDX) analyzer were
used to characterize the membrane foulants. Results showed that the
removal efficiencies of COD, TSS, NH3-N and PO4
3- were 93, 98, 80
and 30% respectively. On average 91% of influent soluble microbial
products (SMP) were eliminated, with the eliminations of
polysaccharides mostly above 80%. The main fouling resistance was
cake resistance. It should be noted that SMP were found in major
portions of mixed liquor that played a relatively significant role in
membrane fouling. SEM and EDX analyses indicated that the
foulants covering the membrane surfaces comprises not only organic
substances but also inorganic elements including Mg, Ca, Al, K and
P.
Abstract: It is well known that during the developments in the
economic sector and through the financial crises occur everywhere in
the whole world, volatility measurement is the most important
concept in financial time series. Therefore in this paper we discuss
the volatility for Amman stocks market (Jordan) for certain period of
time. Since wavelet transform is one of the most famous filtering
methods and grows up very quickly in the last decade, we compare
this method with the traditional technique, Fast Fourier transform to
decide the best method for analyzing the volatility. The comparison
will be done on some of the statistical properties by using Matlab
program.
Abstract: The world demand for potable water is
increasing every day with growing population. Desalination
using solar energy is suitable for potable water production
from brackish and seawater. In this paper, we present a
theoretical study of solar distillation in a single basin under
the open environmental conditions of Chabahar-Iran. The still
has a base area of 2000mm×500mm with a glass cover
inclined at 25° in order to obtain extra solar energy. We model
the still and conduct its energy balance equations under minor
assumptions. We computed the temperatures of glass cover,
seawater interface, moist air and bottom using numerical
method. The investigation addressed the following: The still
productivity, distilled water salinity and still performance in
terms of the still efficiency. Calculated still productivity in
July was higher than December. So in this paper, we show
that still productivity is directly functioning of solar radiation.
Abstract: Car failure detection is a complicated process and
requires high level of expertise. Any attempt of developing an expert
system dealing with car failure detection has to overcome various
difficulties. This paper describes a proposed knowledge-based
system for car failure detection. The paper explains the need for an
expert system and the some issues on developing knowledge-based
systems, the car failure detection process and the difficulties involved
in developing the system. The system structure and its components
and their functions are described. The system has about 150 rules for
different types of failures and causes. It can detect over 100 types of
failures. The system has been tested and gave promising results.
Abstract: The paper presents the modeling of nonlinear
longitudinal aerodynamics using flight data of Hansa-3 aircraft at
high angles of attack near stall. The Kirchhoff-s quasi-steady stall
model has been used to incorporate nonlinear aerodynamic effects in
the aerodynamic model used to estimate the parameters, thereby,
making the aerodynamic model nonlinear. The Maximum Likelihood
method has been applied to the flight data (at high angles of attack)
for the estimation of parameters (aerodynamic and stall
characteristics) using the nonlinear aerodynamic model. To improve
the accuracy level of the estimates, an approach of fixing the strong
parameters has also been presented.
Abstract: The position and momentum space information entropies
of hydrogen atom are exactly evaluated. Using isospectral
Hamiltonian approach, a family of isospectral potentials is constructed having same energy eigenvalues as that of the original potential. The information entropy content is obtained in position
space as well as in momentum space. It is shown that the information
entropy content in each level can be re-arranged as a function of deformation parameter.
Abstract: An empirical study of web applications that use
software frameworks is presented here. The analysis is based on two
approaches. In the first, developers using such frameworks are
required, based on their experience, to assign weights to parameters
such as database connection. In the second approach, a performance
testing tool, OpenSTA, is used to compute start time and other such
measures. From such an analysis, it is concluded that open source
software is superior to proprietary software. The motivation behind
this research is to examine ways in which a quantitative assessment
can be made of software in general and frameworks in particular.
Concepts such as metrics and architectural styles are discussed along
with previously published research.
Abstract: The hand is one of the essential parts of the body for
carrying out Activities of Daily Living (ADLs). Individuals use their
hands and fingers in everyday activities in the both the workplace
and home. Hand-intensive tasks require diverse and sometimes
extreme levels of exertion, depending on the action, movement or
manipulation involved. The authors have undertaken several studies
looking at grip choice and comfort. It is hoped that in providing
improved understanding of discomfort during ADLs this will aid in
the design of consumer products.
Previous work by the authors outlined a methodology for
calculating pain frequency and pain level for a range of tasks. From
an online survey undertaken by the authors with regards
manipulating objects during everyday tasks, tasks involving
gripping were seen to produce the highest levels of pain and
discomfort. Questioning of the participants showed that cleaning
tasks were seen to be ADL's that produced the highest levels of
discomfort, with women feeling higher levels of discomfort than
men.
This paper looks at the methodology for calculating pain
frequency and pain level with particular regards to gripping
activities. This methodology shows that activities such as mopping,
sweeping and hoovering shows the highest numbers of pain
frequency and pain level at 3112.5 frequency per month while the
pain level per person doing this action was 0.78.The study then uses
thin-film force sensors to analyze the force distribution in the hand
whilst hoovering and compares this for differing grip styles and
genders. Women were seen to have more of their hand under a
higher pressure than men when undertaking hoovering. This
suggests that women may feel greater discomfort than men since
their hand is at a higher pressure more of the time.
Abstract: The most important parameter in transformers life
expectancy is the hot-spot temperature level which accelerates the
rate of aging of the insulation. The aim of this paper is to present
thermal models for transformers loaded at prefabricated MV/LV
transformer substations and outdoor situations. The hot-spot
temperature of transformers is studied using their top-oil temperature
rise models. The thermal models proposed for hot-spot and top-oil
temperatures of different operating situations are compared. Since the
thermal transfer is different for indoor and outdoor transformers
considering their operating conditions, their hot-spot thermal models
differ from each other. The proposed thermal models are verified by
the results obtained from the experiments carried out on a typical
1600 kVA, 30 /0.4 kV, ONAN transformer for both indoor and
outdoor situations.
Abstract: This paper proposed a novel model for short term load
forecast (STLF) in the electricity market. The prior electricity
demand data are treated as time series. The model is composed of
several neural networks whose data are processed using a wavelet
technique. The model is created in the form of a simulation program
written with MATLAB. The load data are treated as time series data.
They are decomposed into several wavelet coefficient series using
the wavelet transform technique known as Non-decimated Wavelet
Transform (NWT). The reason for using this technique is the belief
in the possibility of extracting hidden patterns from the time series
data. The wavelet coefficient series are used to train the neural
networks (NNs) and used as the inputs to the NNs for electricity load
prediction. The Scale Conjugate Gradient (SCG) algorithm is used as
the learning algorithm for the NNs. To get the final forecast data, the
outputs from the NNs are recombined using the same wavelet
technique. The model was evaluated with the electricity load data of
Electronic Engineering Department in Mandalay Technological
University in Myanmar. The simulation results showed that the
model was capable of producing a reasonable forecasting accuracy in
STLF.
Abstract: Subsurface erosion in river banks and its details, in
spite of its occurrence in various parts of the world has rarely been
paid attention by researchers. In this paper, quantitative concept of
the subsurface bank erosion has been investigated for vertical banks.
Vertical banks were simulated experimentally by considering a sandy
erodible layer overlaid by clayey one under uniformly distributed
constant overhead pressure. Results of the experiments are indicated
that rate of sandy layer erosion is decreased by an increase in
overburden; likewise, substituting 20% of coarse (3.5 mm) sand layer
bed material by fine material (1.4 mm) may lead to a decrease in
erosion rate by one-third. This signifies the importance of the bed
material composition effect on sandy layers erosion due to subsurface
erosion in river banks.
Abstract: Reciprocating compressors are flexible to handle wide capacity and condition swings, offer a very efficient method of compressing almost any gas mixture in wide range of pressure, can generate high head independent of density, and have numerous applications and wide power ratings. These make them vital component in various units of industrial plants. In this paper optimum reciprocating compressor configuration regarding interstage pressures, low suction pressure, non-lubricated cylinder, speed of machine, capacity control system, compressor valve, lubrication system, piston rod coating, cylinder liner material, barring device, pressure drops, rod load, pin reversal, discharge temperature, cylinder coolant system, performance, flow, coupling, special tools, condition monitoring (including vibration, thermal and rod drop monitoring), commercial points, delivery and acoustic conditions are presented.
Abstract: This study aims to propose three evaluation methods to
evaluate the Tokyo Cap and Trade Program when emissions trading is
performed virtually among enterprises, focusing on carbon dioxide
(CO2), which is the only emitted greenhouse gas that tends to increase.
The first method clarifies the optimum reduction rate for the highest
cost benefit, the second discusses emissions trading among enterprises
through market trading, and the third verifies long-term emissions
trading during the term of the plan (2010-2019), checking the validity
of emissions trading partly using Geographic Information Systems
(GIS). The findings of this study can be summarized in the following
three points.
1. Since the total cost benefit is the greatest at a 44% reduction rate, it
is possible to set it more highly than that of the Tokyo Cap and
Trade Program to get more total cost benefit.
2. At a 44% reduction rate, among 320 enterprises, 8 purchasing
enterprises and 245 sales enterprises gain profits from emissions
trading, and 67 enterprises perform voluntary reduction without
conducting emissions trading. Therefore, to further promote
emissions trading, it is necessary to increase the sales volumes of
emissions trading in addition to sales enterprises by increasing the
number of purchasing enterprises.
3. Compared to short-term emissions trading, there are few enterprises
which benefit in each year through the long-term emissions trading
of the Tokyo Cap and Trade Program. Only 81 enterprises at the
most can gain profits from emissions trading in FY 2019. Therefore,
by setting the reduction rate more highly, it is necessary to increase
the number of enterprises that participate in emissions trading and
benefit from the restraint of CO2 emissions.
Abstract: The Shanghai Cooperation Organization is one of the successful outcomes of China's foreign policy since the end of the Cold war. The expansion of multilateral ties all over the world by dint of pursuing institutional strategies as SCO, identify China as a more constructive power. SCO became a new model of cooperation that was formed on remains of collapsed Soviet system, and predetermined China's geopolitical role in the region. As the fast developing effective regional mechanism, SCO today has more of external impact on the international system and forms a new type of interaction for promoting China's grand strategy of 'peaceful rise'.
Abstract: Information on weed distribution within the field is necessary to implement spatially variable herbicide application. Since hand labor is costly, an automated weed control system could be feasible. This paper deals with the development of an algorithm for real time specific weed recognition system based on Histogram Maxima with threshold of an image that is used for the weed classification. This algorithm is specifically developed to classify images into broad and narrow class for real-time selective herbicide application. The developed system has been tested on weeds in the lab, which have shown that the system to be very effectiveness in weed identification. Further the results show a very reliable performance on images of weeds taken under varying field conditions. The analysis of the results shows over 95 percent classification accuracy over 140 sample images (broad and narrow) with 70 samples from each category of weeds.