Abstract: A Vehicle-s door wireing harness arrangement structure is provided. In vehicle-s door wiring harness(W/H) system is more toward to arrange a passenger compartment than a hinge and a weatherstrip. This article gives some insight into the dimensioning process, with special focus on large deflection analysis of wiring harness(W/H) in vehicle-s door structures for durability problem. An Finite elements analysis for door wiring harness(W/H) are used for residual stresses and dimensional stability with bending flexible. Durability test data for slim test specimens were compared with the numerical predicted fatigue life for verification. The final lifing of the component combines the effects of these microstructural features with the complex stress state arising from the combined service loading and residual stresses.
Abstract: pH-sensitive drug targeting using nanoparticles for
cancer chemotherapy have been spotlighted in recent decades. Graft
copolymer composed of poly (L-histidine) (PHS) and dextran
(DexPHS) was synthesized and pH-sensitive nanoparticles were
fabricated for pH-responsive drug delivery of doxorubicin (DOX).
Nanoparticles of DexPHS showed pH-sensitive changes in particle
sizes and drug release behavior, i.e. particle sizes and drug release rate
were increased at acidic pH, indicating that DexPHS nanoparticles
have pH-sensitive drug delivery potentials. Antitumor activity of
DOX-incorporated DexPHS nanoparticles were studied using CT26
colorectal carcinoma cells. Results indicated that fluorescence
intensity was higher at acidic pH than basic pH. These results
indicated that DexPHS nanoparticles have pH-responsive drug
targeting.
Abstract: This paper describes a low-voltage and low-power
channel selection analog front end with continuous-time low pass
filters and highly linear programmable gain amplifier (PGA). The
filters were realized as balanced Gm-C biquadratic filters to achieve a
low current consumption. High linearity and a constant wide
bandwidth are achieved by using a new transconductance (Gm) cell.
The PGA has a voltage gain varying from 0 to 65dB, while
maintaining a constant bandwidth. A filter tuning circuit that requires
an accurate time base but no external components is presented.
With a 1-Vrms differential input and output, the filter achieves
-85dB THD and a 78dB signal-to-noise ratio. Both the filter and PGA
were implemented in a 0.18um 1P6M n-well CMOS process. They
consume 3.2mW from a 1.8V power supply and occupy an area of
0.19mm2.
Abstract: Since hyaluronic acid (HA) receptor such as CD44 is
over-expressed at sites of cancer cells, HA can be used as a targeting
vehicles for anti-cancer drugs. The aim of this study is to synthesize
block copolymer composed of hyaluronic acid and
poly(ε-caprolactone) (HAPCL) and to fabricate polymeric micelles for
anticancer drug targeting against CD44 receptor of tumor cells.
Chemical composition of HAPCL was confirmed using 1H NMR
spectroscopy. Doxorubicin (DOX) was incorporated into polymeric
micelles of HAPCL. The diameters of HAPHS polymeric micelles
were changed around 80nm and have spherical shapes. Targeting
potential was investigated using CD44-overexpressing. When
DOX-incorporated polymeric micelles was added to KB cells, they
revealed strong red fluorescence color while blocking of CD44
receptor by pretreatment of free HA resulted in reduced intensity,
indicating that HAPCL polymeric micelles have targetability against
CD44 receptor.
Abstract: Search for a tertiary substructure that geometrically
matches the 3D pattern of the binding site of a well-studied protein provides a solution to predict protein functions. In our previous work,
a web server has been built to predict protein-ligand binding sites
based on automatically extracted templates. However, a drawback of such templates is that the web server was prone to resulting in many
false positive matches. In this study, we present a sequence-order constraint to reduce the false positive matches of using automatically
extracted templates to predict protein-ligand binding sites. The binding site predictor comprises i) an automatically constructed template library and ii) a local structure alignment algorithm for
querying the library. The sequence-order constraint is employed to
identify the inconsistency between the local regions of the query protein and the templates. Experimental results reveal that the sequence-order constraint can largely reduce the false positive matches and is effective for template-based binding site prediction.
Abstract: When cars are released from the factory, strut noises are very small and therefore it is difficult to perceive them. As the use time and travel distance increase, however, strut noises get larger so as to cause users much uneasiness. The noises generated at the field include engine noises and flow noises and therefore it is difficult to clearly discern the noises generated from struts. This study developed a test method which can reproduce field strut noises in the lab. Using the newly developed noise evaluation test, this study analyzed the effects that insulator performance degradation and failure can have on car noises. The study also confirmed that the insulator durability test by the simple back-and-forth motion cannot completely reflect the state of the parts failure in the field. Based on this, the study also confirmed that field noises can be reproduced through a durability test that considers heat aging.
Abstract: Tofurther advance research on immune-related genes
from T. molitor, we constructed acDNA library and analyzed
expressed sequence taq (EST) sequences from 1,056 clones. After
removing vector sequence and quality checkingthrough thePhred
program (trim_alt 0.05 (P-score>20), 1039 sequences were generated.
The average length of insert was 792 bp. In addition, we identified 162
clusters, 167 contigs and 391 contigs after clustering and assembling
process using a TGICL package. EST sequences were searchedagainst
NCBI nr database by local BLAST (blastx, E
Abstract: Reno-pin contact test is a method that is controlled by
DC motor used to characterize electronic chips. This method is used in
electronic and telecommunication devices. A new electric
performance testing system is developed in which the testing method
is controlled by using Piezoelectric Transducer (PZT) instead of DC
motor which reduces vibration and noise. The vertical displacement of
the Reno-pin is very short in the Reno-pin contact testing system. Now
using a flexible guide in the new Reno-pin contact system, the vertical
movement of the Reno-pin is increased many times of the existing
Reno-pin contact testing method using DC motor. Using the present
electric performance testing system with a flexible hinge and PZT
instead of DC motor, manufacturing of electronic chips are able to
characterize chips with low cost and high speed.
Abstract: Electronic seal is an electronic device to check the
authenticity and integrity of freight containers at the point of arrival.
While RFID-based eSeals are gaining more acceptances and there are
also some standardization processes for these devices, a recent
research revealed that the current RFID-based eSeals are vulnerable to
various attacks. In this paper, we provide a feasible solution to
enhance the security of active RFID-based eSeals. Our approach is to
use an authentication and key agreement protocol between eSeal and
reader device, enabling data encryption and integrity check. Our
protocol is based on the use of block cipher AES, which is reasonable
since a block cipher can also be used for many other security purposes
including data encryption and pseudo-random number generation. Our
protocol is very simple, and it is applicable to low-end active RFID
eSeals.
Abstract: Most paddy rice fields in East Asia are small parcels,
and the weather conditions during the growing season are usually
cloudy. FORMOSAT-2 multi-spectral images have an 8-meter
resolution and one-day recurrence, ideal for mapping paddy rice fields
in East Asia. To map rice fields, this study first determined the
transplanting and the most active tillering stages of paddy rice and
then used multi-temporal images to distinguish different growing
characteristics between paddy rice and other ground covers. The
unsupervised ISODATA (iterative self-organizing data analysis
techniques) and supervised maximum likelihood were both used to
discriminate paddy rice fields, with training areas automatically
derived from ten-year cultivation parcels in Taiwan. Besides original
bands in multi-spectral images, we also generated normalized
difference vegetation index and experimented with object-based
pre-classification and post-classification. This paper discusses results
of different image classification methods in an attempt to find a
precise and automatic solution to mapping paddy rice in Taiwan.
Abstract: In recent years, several severe large-scale influenza
outbreaks happened in many countries, such as SARS in 2005 or
H1N1 in 2009. Those influenza Epidemics have greatly impacts not
only on people-s life and health, but medical systems in different
countries. Although severe diseases are more experienced, they are not
fully controlled. Governments have different policies to control the
spreads of diseases. However, those policies have both positive and
negative social or economical influence on people and society.
Therefore, it is necessary and essential to develop an appropriate
model for evaluations of policies. Consequently, a proper measure can
be implemented to confront the diseases. The main goal of this study is
to develop a SIR-based model for the further evaluations of the
candidate policies during the influenza outbreaks.
Abstract: Many well-known interconnection networks, such as kary n-cubes, recursive circulant graphs, generalized recursive circulant graphs, circulant graphs and so on, are shown to belong to the family of cycle composition networks. Recently, various studies about mutually independent hamiltonian cycles, abbreviated as MIHC-s, on interconnection networks are published. In this paper, using an improved construction method, we obtain MIHC-s on cycle composition networks with a much weaker condition than the known result. In fact, we established the existence of MIHC-s in the cycle composition networks and the result is optimal in the sense that the number of MIHC-s we constructed is maximal.
Abstract: Not only is municipal pattern the institution basement of urban management, but it also determines the forms of the management results. There-s a considerable possibility of bankruptcy for China-s current municipal pattern as it-s an overdraft of land deal in fact. Based on the analysis of China-s current municipal pattern, the passage proposed an assumption of a new pattern verified legitimacy by conceptual as well as econometric models. Conclusion is: the added supernumerary value of investment in public goods was not included in China-s current municipal pattern, but hidden in the rising housing prices; we should set housing tax or municipal tax to optimize the municipal pattern, to correct the behavior of local governments and to ensure the regular development of China-s urbanization.
Abstract: This research aims to analyze the regenerative burner and the recuperative burner for the different reheating furnaces in the steel industry. The warm air temperatures of the burners are determined to suit with the sizes of the reheating furnaces by considering the air temperature, the fuel cost and the investment cost. The calculations of the payback period and the net present value are studied to compare the burners for the different reheating furnaces. The energy balance is utilized to calculate and compare the energy used in the different sizes of reheating furnaces for each burner. It is found that the warm air temperature is different if the sizes of reheating furnaces are varied. Based on the considerations of the net present value and the payback period, the regenerative burner is suitable for all plants at the same life of the burner. Finally, the sensitivity analysis of all factors has been discussed in this research.
Abstract: The coalescer process is one of the methods for oily water treatment by increasing the oil droplet size in order to enhance the separating velocity and thus effective separation. However, the presence of surfactants in an oily emulsion can limit the obtained mechanisms due to the small oil size related with stabilized emulsion. In this regard, the purpose of this research is to improve the efficiency of the coalescer process for treating the stabilized emulsion. The effects of bed types, bed height, liquid flow rate and stage coalescer (step-bed) on the treatment efficiencies in term of COD values were studied. Note that the treatment efficiency obtained experimentally was estimated by using the COD values and oil droplet size distribution. The study has shown that the plastic media has more effective to attach with oil particles than the stainless one due to their hydrophobic properties. Furthermore, the suitable bed height (3.5 cm) and step bed (3.5 cm with 2 steps) were necessary in order to well obtain the coalescer performance. The application of step bed coalescer process in reactor has provided the higher treatment efficiencies in term of COD removal than those obtained with classical process. The proposed model for predicting the area under curve and thus treatment efficiency, based on the single collector efficiency (ηT) and the attachment efficiency (α), provides relatively a good coincidence between the experimental and predicted values of treatment efficiencies in this study.
Abstract: In this study, workplace environmental monitoring
systems were established using USN(Ubiquitous Sensor Networks)
and LabVIEW. Although existing direct sampling methods enable
finding accurate values as of the time points of measurement, those
methods are disadvantageous in that continuous management and
supervision are difficult and costs for are high when those methods are
used. Therefore, the efficiency and reliability of workplace
management by supervisors are relatively low when those methods are
used. In this study, systems were established so that information on
workplace environmental factors such as temperatures, humidity and
noises is measured and transmitted to the PC in real time to enable
supervisors to monitor workplaces through LabVIEW on the PC.
When any accidents have occurred in workplaces, supervisors can
immediately respond through the monitoring system and this system
enables integrated workplace management and the prevention of
safety accidents. By introducing these monitoring systems, safety
accidents due to harmful environmental factors in workplaces can be
prevented and these monitoring systems will be also helpful in finding
out the correlation between safety accidents and occupational diseases
by comparing and linking databases established by this monitoring
system with existing statistical data.
Abstract: Fecal sterol has been proposed as a chemical indicator
of human fecal pollution even when fecal coliform populations have
diminished due to water chlorination or toxic effects of industrial
effluents. This paper describes an improved derivatization procedure
for simultaneous determination of four fecal sterols including
coprostanol, epicholestanol, cholesterol and cholestanol using gas
chromatography-mass spectrometry (GC-MS), via optimization study
on silylation procedures using N-O-bis
(trimethylsilyl)-trifluoroacetamide (BSTFA), and
N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide
(MTBSTFA), which lead to the formation of trimethylsilyl (TMS) and
tert-butyldimethylsilyl (TBS) derivatives, respectively. Two
derivatization processes of injection-port derivatization and water bath
derivatization (60 oC, 1h) were inspected and compared. Furthermore,
the methylation procedure at 25 oC for 2h with
trimethylsilydiazomethane (TMSD) for fecal sterols analysis was also
studied. It was found that most of TMS derivatives demonstrated the
highest sensitivities, followed by methylated derivatives. For BSTFA
or MTBSTFA derivatization processes, the simple injection-port
derivatization process could achieve the same efficiency as that in the
tedious water bath derivatization procedure.
Abstract: For this study, this researcher conducted a precision
network adjustment with QOCA, the precision network adjustment
software developed by Jet Propulsion Laboratory, to perform an
integrated network adjustment on the Unified Control Points managed
by the National Geographic Information Institute. Towards this end,
275 Unified Control Points observed in 2008 were selected before a
network adjustment is performed on those 275 Unified Control Points.
The RMSE on the discrepancies of coordinates as compared to the
results of GLOBK was ±6.07mm along the N axis, ±2.68mm along the
E axis and ±6.49mm along the U axis.
Abstract: This paper presents the source extraction system which can extract only target signals with constraints on source localization in on-line systems. The proposed system is a kind of methods for enhancing a target signal and suppressing other interference signals. But, the performance of proposed system is superior to any other methods and the extraction of target source is comparatively complete. The method has a beamforming concept and uses an improved time-frequency (TF) mask-based BSS algorithm to separate a target signal from multiple noise sources. The target sources are assumed to be in front and test data was recorded in a reverberant room. The experimental results of the proposed method was evaluated by the PESQ score of real-recording sentences and showed a noticeable speech enhancement.