Abstract: In this work study the location of interface in a stirred vessel with a Concave impeller by computational fluid dynamic was presented. To modeling rotating the impeller, sliding mesh (SM) technique was used and standard k-ε model was selected for turbulence closure. Mean tangential, radial and axial velocities and also turbulent kinetic energy (k) and turbulent dissipation rate (ε) in various points of tank was investigated. Results show sensitivity of system to location of interface and radius of 7 to 10cm for interface in the vessel with existence characteristics cause to increase the accuracy of simulation.
Abstract: A systems approach model for prostate cancer in prostate duct, as a sub-system of the organism is developed. It is accomplished in two steps. First this research work starts with a nonlinear system of coupled Fokker-Plank equations which models continuous process of the system like motion of cells. Then extended to PDEs that include discontinuous processes like cell mutations, proliferation and deaths. The discontinuous processes is modeled by using intensity poisson processes. The model incorporates the features of the prostate duct. The system of PDEs spatial coordinate is along the proximal distal axis. Its parameters depend on features of the prostate duct. The movement of cells is biased towards distal region and mutations of prostate cancer cells is localized in the proximal region. Numerical solutions of the full system of equations are provided, and are exhibit traveling wave fronts phenomena. This motivates the use of the standard transformation to derive a canonically related system of ODEs for traveling wave solutions. The results obtained show persistence of prostate cancer by showing that the non-negative cone for the traveling wave system is time invariant. The traveling waves have a unique global attractor is proved also. Biologically, the global attractor verifies that evolution of prostate cancer stem cells exhibit the avascular tumor growth. These numerical solutions show that altering prostate stem cell movement or mutation of prostate cancer cells lead to avascular tumor. Conclusion with comments on clinical implications of the model is discussed.
Abstract: The paper presents the optimization problem for the
multi-element synthetic transmit aperture method (MSTA) in
ultrasound imaging applications. The optimal choice of the transmit
aperture size is performed as a trade-off between the lateral
resolution, penetration depth and the frame rate. Results of the
analysis obtained by a developed optimization algorithm are
presented. Maximum penetration depth and the best lateral resolution
at given depths are chosen as the optimization criteria. The
optimization algorithm was tested using synthetic aperture data of
point reflectors simulated by Filed II program for Matlab® for the
case of 5MHz 128-element linear transducer array with 0.48 mm
pitch are presented. The visualization of experimentally obtained
synthetic aperture data of a tissue mimicking phantom and in vitro
measurements of the beef liver are also shown. The data were
obtained using the SonixTOUCH Research systemequipped with a
linear 4MHz 128 element transducerwith 0.3 mm element pitch, 0.28
mm element width and 70% fractional bandwidth was excited by one
sine cycle pulse burst of transducer's center frequency.
Abstract: A current mirror (CM) based on self cascode MOSFETs low voltage analog and mixed mode structures has been proposed. The proposed CM has high output impedance and can operate at 0.5 V. P-Spice simulations confirm the high performance of this CM with a bandwidth of 6.0 GHz at input current of 100 μA.