Abstract: Scarcity of water resources and huge costs of
establishing new hydraulic installations necessitate optimal
exploitation from existing reservoirs. Sustainable management and
efficient exploitation from existing finite water resources are
important factors in water resource management, particularly in the
periods of water insufficiency and in dry regions, and on account of
competitive allocations in the view of exploitation management. This
study aims to minimize reservoir water release from a determined
rate of demand. A numerical model for water optimal exploitation
has been developed using GAMS introduced by the World Bank and
applied to the case of Meijaran dam, northern Iran. The results
indicate that this model can optimize the function of reservoir
exploitation while required water for lower parts of the region will be
supplied. Further, allocating optimal water from reservoir, the
optimal rate of water allocated to any group of the users were
specified to increase benefits in curve dam exploitation.
Abstract: Aim of this work was to compare the efficacy of two
loading methods of proteins onto polymeric nanocarriers: adsorption
and encapsulation methods. Preliminary studies of protein loading
were done using Bovine Serum Albumin (BSA) as model protein.
Nanocarriers were prepared starting from polylactic co-glycolic acid
(PLGA) polymer; production methods used are two different variants
of emulsion evaporation method. Nanoparticles obtained were
analyzed in terms of dimensions by Dynamic Light Scattering and
Loading Efficiency of BSA by Bradford Assay. Loaded
nanoparticles were then submitted to in-vitro protein dissolution test
in order to study the effect of the delivery system on the release rate
of the protein.
Abstract: Fuzzy controllers are potential candidates for the
control of nonlinear, time variant and also complicated systems. Anti
lock brake system (ABS) which is a nonlinear system, may not be
easily controlled by classical control methods. An intelligent Fuzzy
control method is very useful for this kind of nonlinear system. A
typical antilock brake system (ABS) by sensing the wheel lockup,
releases the brakes for a short period of time, and then reapplies again
the brakes when the wheel spins up. In this paper, an intelligent fuzzy
ABS controller is designed to adjust slipping performance for variety
of roads. There are tow major sections in the proposing control
system. First section consists of tow Fuzzy-Logic Controllers (FLC)
providing optimal brake torque for both front and rear wheels.
Second section which is also a FLC provides required amount of slip
and torque references properties for different kind of roads.
Simulation results of our proposed intelligent ABS for three different
kinds of road show more reliable and better performance in compare
with two other break systems.
Abstract: The selection of appropriate requirements for product
releases can make a big difference in a product success. The selection
of requirements is done by different requirements prioritization
techniques. These techniques are based on pre-defined and
systematic steps to calculate the requirements relative weight.
Prioritization is complicated by new development settings, shifting
from traditional co-located development to geographically distributed
development. Stakeholders, connected to a project, are distributed all
over the world. These geographically distributions of stakeholders
make it hard to prioritize requirements as each stakeholder have their
own perception and expectations of the requirements in a software
project. This paper discusses limitations of the Analytical Hierarchy
Process with respect to geographically distributed stakeholders-
(GDS) prioritization of requirements. This paper also provides a
solution, in the form of a modified AHP, in order to prioritize
requirements for GDS. We will conduct two experiments in this
paper and will analyze the results in order to discuss AHP limitations
with respect to GDS. The modified AHP variant is also validated in
this paper.
Abstract: The present study addresses problems and solutions
related to new functional food production. Wheat (Triticum aestivum
L) bran obtained from industrial mill company “Dobeles
dzirnavieks”, was used to investigate them as raw material like
nutrients for Bifidobacterium lactis Bb-12. Enzymatic hydrolysis of
wheat bran starch was carried out by α-amylase from Bacillus
amyloliquefaciens (Sigma Aldrich). The Viscozyme L purchased
from (Sigma Aldrich) were used for reducing released sugar.
Bifidibacterium lactis Bb-12 purchased from (Probio-Tec® CHR
Hansen) was cultivated in enzymatically hydrolysed wheat bran
mash. All procedures ensured the number of active Bifidobacterium
lactis Bb-12 in the final product reached 105 CFUg-1. After enzymatic
and bacterial fermentations sample were freeze dried for analysis of
chemical compounds. All experiments were performed at Faculty of
Food Technology of Latvia University of Agriculture in January-
March 2013. The obtained results show that both types of wheat bran
(enzymatically treated and non-treated) influenced the fermentative
activity and number of Bifidibacterium lactis Bb-12 viable in wheat
bran mash. Amount of acidity strongly increase during the wheat
bran mash fermentation. The main objective of this work was to
create low-energy functional enzymatically and bacterially treated
food from wheat bran using enzymatic hydrolysis of carbohydrates
and following cultivation of Bifidobacterium lactis Bb-12.
Abstract: Three dimensional simulations are carried out to estimate the effect of wind direction, wind speed and geometry on the flow and dispersion of vehicular pollutant in a street canyon. The pollutant sources are motor vehicles passing between the two buildings. Suitable emission factors for petrol and diesel vehicles at varying vehicle speed are used for the estimation of the rate of emission from the streets. The dispersion of automobile pollutant released from the street is simulated by introducing vehicular emission source term as a fixed-flux boundary condition at the ground level over the road. The emission source term is suitably calculated by adopting emission factors from literature for varying conditions of street traffic. It is observed that increase in wind angle disturbs the symmetric pattern of pollution distribution along the street length. The concentration increases in the far end of the street as compared to the near end.
Abstract: The nanosized polymeric micelles release the drug
due to acoustic cavitation, which is enhanced in dual frequency
ultrasonic fields. In this study, adult female Balb/C mice were
transplanted with spontaneous breast adenocarcinoma tumors and
were injected with a dose of 1.3 mg/kg doxorubicin in one of three
forms: free doxorubicin, micellar doxorubicin without sonication and
micellar doxorubicin with sonication. To increase cavitation yield,
the tumor region was sonicated with low level dual frequency of 3
MHz and 28 kHz. The animals were sacrificed 24 h after injection,
and their tumor, heart, spleen, liver, kidneys and plasma were
separated and homogenized. The drug content in their tumor, heart,
spleen, liver, kidneys and plasma was determined using tissue
fluorimetry. The results show that in the group that received micellar
doxorubicin with sonication, the drug concentration in the tumor
tissue was nine and three times higher than in the free doxorubicin
group and the micellar doxorubicin without sonication group,
respectively. In the micellar doxorubicin with sonication group, the
drug concentration in other tissues was lower than other groups
(p
Abstract: Five crystal modifications of water insoluble
artesunate were generated by recrystallizing it from various solvents
with improved physicochemical properties. These generated crystal
forms were characterized to select the most potent and soluble form.
SEM of all the forms showed changes in external shape leading them
to be different morphologically. DSC thermograms of Form III and
Form V showed broad endotherm peaks at 83.04oC and 76.96oC prior
to melting fusion of drug respectively. Calculated weight loss in TGA
revealed that Form III and Form V are methanol and acetone solvates
respectively. However, few additional peaks were appeared in XRPD
pattern in these two solvate forms. All forms exhibit exothermic
behavior in buffer and two solvates display maximum ease of
molecular release from the lattice. Methanol and acetone solvates
were found to be most soluble forms and exhibited higher
antimalarial efficacy showing higher survival rate (83.3%) after 30
days.
Abstract: This study investigated a strategy of blending lead-laden sludge and Al-rich precursors to reduce the release of metals from the stabilized products. Using PbO as the simulated lead-laden sludge to sinter with γ-Al2O3 by Pb:Al molar ratios of 1:2 and 1:12, PbAl2O4 and PbAl12O19 were formed as final products during the sintering process, respectively. By firing the PbO + γ-Al2O3 mixtures with different Pb/Al molar ratios at 600 to 1000 °C, the lead transformation was determined through X-ray diffraction (XRD) data. In Pb/Al molar ratio of 1/2 system, the formation of PbAl2O4 is initiated at 700 °C, but an effective formation was observed above 750 °C. An intermediate phase, Pb9Al8O21, was detected in the temperature range of 800-900 °C. However, different incorporation behavior for sintering PbO with Al-rich precursors at a Pb/Al molar ratio of 1/12 was observed during the formation of PbAl12O19 in this system. In the sintering process, both temperature and time effect on the formation of PbAl2O4 and PbAl12O19 phases were estimated. Finally, a prolonged leaching test modified from the U.S. Environmental Protection Agency-s toxicity characteristic leaching procedure (TCLP) was used to evaluate the durability of PbO, Pb9Al8O21, PbAl2O4 and PbAl12O19 phases. Comparison for the leaching results of the four phases demonstrated the higher intrinsic resistance of PbAl12O19 against acid attack.
Abstract: Triglycerides and their derivatives are considered as viable alternatives for diesel fuels. Rice bran oil is used as diesel fuel. Highly viscous rice bran oil can be reduced by blending it with diesel fuel. The present research is aimed to investigate experimentally the performance, exhaust emission and combustion characteristics of a direct injection (DI) diesel engine, typically used in agricultural sector, over the entire load range when fuelled with rice bran oil and diesel fuel blends, RB10 (10% rice bran oil + 90% diesel fuel) to RB50. The performance, emission and combustion parameters of RB20 were found to be very close to neat diesel fuel (ND). The injector opening pressure (IOP) undoubtedly is of prime importance in diesel engine operation. Performance, emission and combustion characteristics with RB30 at enhanced IOPs are better than ND. Improved premixed heat release rate were noticed with RB30 when the IOP is enhanced.
Abstract: This paper describes Clinical Document Architecture Release Two (CDA R2) standard and a client application for messaging with SAĞLIK-NET project developed by The Ministry of Health of Turkey. CDA R2 , developed by Health Level 7 (HL7) organization and approved by American National Standards Institute (ANSI) in 2004, to standardize medical information to be able to share semantically and syntactically. In this study, a client application compatible with HL7 V3 for a project named SAĞLIKNET, aimed to build a National Health Information System by Turkey. Moreover, CDA conformance of this application will also be evaluated.
Abstract: The dispersion of heavy particles line in an isotropic
and incompressible three-dimensional turbulent flow has been
studied using the Kinematic Simulation techniques to find out the
evolution of the line fractal dimension. In this study, the fractal
dimension of the line is found for different cases of heavy particles
inertia (different Stokes numbers) in the absence of the particle
gravity with a comparison with the fractal dimension obtained in the
diffusion case of material line at the same Reynolds number. It can
be concluded for the dispersion of heavy particles line in turbulent
flow that the particle inertia affect the fractal dimension of a line
released in a turbulent flow for Stokes numbers 0.02 < St < 2. At the
beginning for small times, most of the different cases are not affected
by the inertia until a certain time, the particle response time τa, with
larger time as the particles inertia increases, the fractal dimension of
the line increases owing to the particles becoming more sensitive to
the small scales which cause the change in the line shape during its
journey.
Abstract: Different agricultural waste peels were assessed for
their suitability to be used as primary substrates for the
bioremediation of free cyanide (CN-) by a cyanide-degrading fungus
Aspergillus awamori isolated from cyanide containing wastewater.
The bioremediated CN- concentration were in the range of 36 to 110
mg CN-/L, with Orange (C. sinensis) > Carrot (D. carota) > Onion
(A. cepa) > Apple (M. pumila), being chosen as suitable substrates
for large scale CN- degradation processes due to: 1) the high
concentration of bioremediated CN-, 2) total reduced sugars released
into solution to sustain the biocatalyst, and 3) minimal residual NH4-
N concentration after fermentation. The bioremediation rate constants
(k) were 0.017h-1 (0h < t < 24h), with improved bioremediation rates
(0.02189h-1) observed after 24h. The averaged nitrilase activity was
~10 U/L.
Abstract: Female breast cancer is the second in frequency after cervical cancer. Surgery is the most common treatment for breast cancer, followed by chemotherapy as a treatment of choice. Although effective, it causes serious side effects. Controlled-release drug delivery is an alternative method to improve the efficacy and safety of the treatment. It can release the dosage of drug between the minimum effect concentration (MEC) and minimum toxic concentration (MTC) within tumor tissue and reduce the damage of normal tissue and the side effect. Because an in vivo experiment of this system can be time-consuming and labor-intensive, a mathematical model is desired to study the effects of important parameters before the experiments are performed. Here, we describe a 3D mathematical model to predict the release of doxorubicin from pluronic gel to treat human breast cancer. This model can, ultimately, be used to effectively design the in vivo experiments.
Abstract: Fly ash is one of the residues generated in
combustion, and comprises the fine particles that rise with the flue
gases. Ash which does not rise is termed bottom ash [1]. In our
country, it is expected that will be occurred 50 million tons of waste
ash per year until 2020. Released waste from the thermal power
plants is caused very significant problems as known. The fly ashes
can be evaluated by using as adsorbent material.
The purpose of this study is to investigate the possibility of use of
Tuncbilek fly ash like low-cost adsorbents for heavy metal
adsorption. First of all, Tuncbilek fly ash was characterized. For this
purpose; analysis such as sieve analysis, XRD, XRF, SEM and FT-IR
were performed.
Abstract: System testing is actually done to the entire system
against the Functional Requirement Specification and/or the System
Requirement Specification. Moreover, it is an investigatory testing
phase, where the focus is to have almost a destructive attitude and
test not only the design, but also the behavior and even the believed
expectations of the customer. It is also intended to test up to and
beyond the bounds defined in the software/hardware requirements
specifications. In Motorola®, Automated Testing is one of the testing
methodologies uses by GSG-iSGT (Global Software Group - iDEN
TM
Subcriber Group-Test) to increase the testing volume, productivity
and reduce test cycle-time in iDEN
TM
phones testing. Testing is able
to produce more robust products before release to the market. In this
paper, iHopper is proposed as a tool to perform stress test on iDEN
TM
phonse. We will discuss the value that automation has brought to
iDEN
TM
Phone testing such as improving software quality in the
iDEN
TM
phone together with some metrics. We will also look into
the advantages of the proposed system and some discussion of the
future work as well.
Abstract: We evaluated the effect of sensory (direct current
(DC), 600μA) and motor (monophasic current, pulse duration 300μs,
100 Hz, 2.5-3mA) intensities of cathodal electrical stimulation (ES)
current to release VEGF and biomechanical properties of wound. 54
male Sprague-dawley rats were randomly assigned into one control
and two experimental groups. A full thickness skin incision was
made on animals- dorsal region. The experimental groups received
ES for 1h/day and every other day. VEGF expression was measured
in skin on the 7th day after surgical incision and tensile strength was
measured on 21st day. On the 7th day, the values of skin VEGF in the
sensory group were significantly greater than those of the other
groups (p < 0.05). Sensory and Motor intensity stimulation, can not
improve the biomechanical properties of the repaired wounds.
It seems the mechanical environment induced by sensory and
motor intensity of electrical stimulation, could not simulate the role
of normal daily stress and strain to maturation of collagen fibers and
their cross links. Further work is needed to determine the relationship
between VEGF expression after ES and its effect on tensile strength
of healed wound.
Abstract: Long Term Evolution (LTE) is a 4G wireless
broadband technology developed by the Third Generation
Partnership Project (3GPP) release 8, and it's represent the
competitiveness of Universal Mobile Telecommunications System
(UMTS) for the next 10 years and beyond. The concepts for LTE
systems have been introduced in 3GPP release 8, with objective of
high-data-rate, low-latency and packet-optimized radio access
technology. In this paper, performance of different TCP variants
during LTE network investigated. The performance of TCP over
LTE is affected mostly by the links of the wired network and total
bandwidth available at the serving base station. This paper describes
an NS-2 based simulation analysis of TCP-Vegas, TCP-Tahoe, TCPReno,
TCP-Newreno, TCP-SACK, and TCP-FACK, with full
modeling of all traffics of LTE system. The Evaluation of the
network performance with all TCP variants is mainly based on
throughput, average delay and lost packet. The analysis of TCP
performance over LTE ensures that all TCP's have a similar
throughput and the best performance return to TCP-Vegas than other
variants.
Abstract: In this paper delamination phenomenon in
Carbon-Epoxy laminated composite material is investigated
numerically. Arcan apparatus and specimen is modeled in ABAQUS
finite element software for different loading conditions and crack
geometries. The influence of variation of crack geometry on
interlaminar fracture stress intensity factor and energy release rate for
various mixed mode ratios and pure mode I and II was studied. Also,
correction factors for this specimen for different crack length ratios
were calculated. The finite element results indicate that for loading
angles close to pure mode-II loading, a high ratio of mode-II to
mode-I fracture is dominant and there is an opposite trend for loading
angles close to pure mode-I loading. It confirms that by varying the
loading angle of Arcan specimen pure mode-I, pure mode-II and a
wide range of mixed-mode loading conditions can be created and
tested. Also, numerical results confirm that the increase of the mode-
II loading contribution leads to an increase of fracture resistance in
the CF/PEI composite (i.e., a reduction in the total strain energy
release rate) and the increase of the crack length leads to a reduction
of interlaminar fracture resistance in the CF/PEI composite (i.e., an
increase in the total interlaminar strain energy release rate).
Abstract: The current paper conceptualizes the technique of
release consistency indispensable with the concept of
synchronization that is user-defined. Programming model concreted
with object and class is illustrated and demonstrated. The essence of
the paper is phases, events and parallel computing execution .The
technique by which the values are visible on shared variables is
implemented. The second part of the paper consist of user defined
high level synchronization primitives implementation and system
architecture with memory protocols. There is a proposition of
techniques which are core in deciding the validating and invalidating
a stall page .