Abstract: The paper presents a plastic analysis procedure based
on the energy balance concept for performance based seismic retrofit
of multi-story multi-bay masonry infilled reinforced concrete (R/C)
frames with a ‘soft’ ground story using passive energy dissipation
(PED) devices with the objective of achieving a target performance
level of the retrofitted R/C frame for a given seismic hazard level at
the building site. The proposed energy based plastic analysis
procedure was employed for developing performance based design
(PBD) formulations for PED devices for a simulated application in
seismic retrofit of existing frame structures designed in compliance
with the prevalent standard codes of practice. The PBD formulations
developed for PED devices were implemented for simulated seismic
retrofit of a representative code-compliant masonry infilled R/C
frame with a ‘soft’ ground story using friction dampers as the PED
device. Non-linear dynamic analyses of the retrofitted masonry
infilled R/C frames is performed to investigate the efficacy and
accuracy of the proposed energy based plastic analysis procedure in
achieving the target performance level under design level
earthquakes. Results of non-linear dynamic analyses demonstrate that
the maximum inter-story drifts in the masonry infilled R/C frames
with a ‘soft’ ground story that is retrofitted with the friction dampers
designed using the proposed PBD formulations are controlled within
the target drifts under near-field as well far-field earthquakes.
Abstract: The main purpose of this work was verify the
influence of the accelerated carbonation in the physical and
mechanical properties of the hybrid composites, reinforced with
micro and nanofibers and composites with microfibers. The
composites were produced by the slurry vacuum dewatering method,
followed by pressing. It was produced using two formulations: 8% of
eucalyptus pulp + 1% of the nanofibrillated cellulose and 9% of
eucalyptus pulp, both were subjected to accelerated carbonation. The
results showed that the accelerated carbonation contributed to
improve the physical and mechanical properties of the hybrid
composites and of the composites reinforced with microfibers
(eucalyptus pulp).
Abstract: In this paper, the formulation of a new group explicit
method with a fourth order accuracy is described in solving the two
dimensional Helmholtz equation. The formulation is based on the
nine-point fourth order compact finite difference approximation
formula. The complexity analysis of the developed scheme is also
presented. Several numerical experiments were conducted to test the
feasibility of the developed scheme. Comparisons with other existing
schemes will be reported and discussed. Preliminary results indicate
that this method is a viable alternative high accuracy solver to the
Helmholtz equation.
Abstract: Present study is aimed on the cutting process of circular
cross-section rods where the fracture is used to separate one rod
into two pieces. Incorporating the phenomenological ductile fracture
model into the explicit formulation of finite element method, the
process can be analyzed without the necessity of realizing too many
real experiments which could be expensive in case of repetitive
testing in different conditions. In the present paper, the steel AISI
1045 was examined and the tensile tests of smooth and notched
cylindrical bars were conducted together with biaxial testing of the
notched tube specimens to calibrate material constants of selected
phenomenological ductile fracture models. These were implemented
into the Abaqus/Explicit through user subroutine VUMAT and used
for cutting process simulation. As the calibration process is based
on variables which cannot be obtained directly from experiments,
numerical simulations of fracture tests are inevitable part of the
calibration. Finally, experiments regarding the cutting process were
carried out and predictive capability of selected fracture models is
discussed. Concluding remarks then make the summary of gained
experience both with the calibration and application of particular
ductile fracture criteria.
Abstract: In the present work, the finite element formulation for
the investigation of the effects of a localized interfacial degeneration
on the dynamic behavior of the [90°/0°] laminated composite plate
employing the state-space technique is performed. The stiffness of
the laminate is determined by assembling the stiffnesses of subelements.
This includes an introduction of an interface layer adopting
the virtually zero-thickness formulation to model the interfacial
degeneration. Also, the kinematically consistent mass matrix and
proportional damping have been formulated to complete the free
vibration governing expression. To simulate the interfacial
degeneration of the laminate, the degenerated areas are defined from
the center propagating outwards in a localized manner. It is found
that the natural frequency, damped frequency and damping ratio of
the plate decreases as the degenerated area of the interface increases.
On the contrary, the loss factor increases correspondingly.
Abstract: Due to the large amount of information in the World
Wide Web (WWW, web) and the lengthy and usually linearly
ordered result lists of web search engines that do not indicate
semantic relationships between their entries, the search for topically
similar and related documents can become a tedious task. Especially,
the process of formulating queries with proper terms representing
specific information needs requires much effort from the user. This
problem gets even bigger when the user's knowledge on a subject and
its technical terms is not sufficient enough to do so. This article
presents the new and interactive search application DocAnalyser that
addresses this problem by enabling users to find similar and related
web documents based on automatic query formulation and state-ofthe-
art search word extraction. Additionally, this tool can be used to
track topics across semantically connected web documents.
Abstract: Folic acid (FA) is known to be an important
supplement to prevent neural tube defect (NTD) in pregnant women.
Similar to some commercial formulations, sodium bicarbonate
solution is used as a solvent for FA. This work uses the antisolvent
vapour precipitation (AVP), incorporating ethanol vapour as the
convective drying medium in place of air to produce branch-like
micro-structure FA particles. Interestingly, the dissolution rate of the
resultant particle is 2-3 times better than the particle produce from
conventional air drying due to the higher surface area of particles
produced. The higher dissolution rate could possibly improve the
delivery and absorption of FA in human body. This application could
potentially be extended to other commercial products, particularly in
less soluble drugs to improve its solubility.
Abstract: Mass flow measurement is the basis of most technoeconomic
formulations in the chemical industry. This calls for
reliable and accurate detection of mass flow. Flow measurement
laboratory experiments were conducted using various instruments.
These consisted of orifice plates, various sized rotameters, wet gas
meter and soap bubble meter. This work was aimed at evaluating
appropriate operating conditions and accuracy of the aforementioned
devices. The experimental data collected were compared to
theoretical predictions from Bernoulli’s equation and calibration
curves supplied by the instrument’s manufacturers. The results
obtained showed that rotameters were more reliable for measuring
high and low flow rates; while soap-bubble meters and wet-gas
meters were found to be suitable for measuring low flow rates. The
laboratory procedures and findings of the actual work can assist
engineering students and professionals in conducting their flow
measurement laboratory test work.
Abstract: A simple, accurate and precise direct spectrophotometric method has been developed for the determination of cefixime in tablets and capsules. The method is based on the reaction of cefixime with a mixture of potassium iodide and potassium iodate to form yellow coloured product in ethanol-distilled water medium at room temperature which absorbed maximally at 352 nm. The factors affecting the reaction product were carefully studied and optimized. The validation parameters based on International Conference on Harmonisation (ICH, USA) guidelines were followed. The effect of common excipients used as additives has been tested and the tolerance limit was calculated for the determination of cefixime. Beer’s law is obeyed in the concentration range of 4 – 24 ug mL-1 with apparent molar absorptivity of 1.52 × 104 L mol-1cm-1 and Sandell’s sensitivity of 0.033 ug/cm2/ 0.001 absorbance unit. The limits of detection and quantitation for the proposed method are 0.32 and 1.06 ug mL-1, respectively. The proposed method has been successfully applied for the determination of cefixime in pharmaceutical formulations. The results obtained by the proposed method were statistically compared with the reference method using t- and F- values and found no significant difference between the two methods. The proposed method can be used as an alternate method for routine quality control analysis of cefixime in pharmaceutical formulations.
Abstract: A generalized vortex lattice method for complex
lifting surfaces with flap and aileron deflection is formulated. The
method is not restricted by the linearized theory assumption and
accounts for all standard geometric lifting surface parameters:
camber, taper, sweep, washout, dihedral, in addition to flap and
aileron deflection. Thickness is not accounted for since the physical
lifting body is replaced by a lattice of panels located on the mean
camber surface. This panel lattice setup and the treatment of different
wake geometries is what distinguish the present work form the
overwhelming majority of previous solutions based on the vortex
lattice method. A MATLAB code implementing the proposed
formulation is developed and validated by comparing our results to
existing experimental and numerical ones and good agreement is
demonstrated. It is then used to study the accuracy of the widely used
classical vortex-lattice method. It is shown that the classical approach
gives good agreement in the clean configuration but is off by as much
as 30% when a flap or aileron deflection of 30° is imposed. This
discrepancy is mainly due the linearized theory assumption
associated with the conventional method. A comparison of the effect
of four different wake geometries on the values of aerodynamic
coefficients was also carried out and it is found that the choice of the
wake shape had very little effect on the results.
Abstract: Fluid rheology may have essential impact on sound propagation in a liquid-filled pipe, especially, in a low frequency range. Rheological parameters of liquid are temperature-sensitive, which ultimately results in a temperature dependence of the wave speed and attenuation in the waveguide. The study is devoted to modeling of this effect at sound propagation in an elastic pipe with polymeric liquid, described by generalized Maxwell model with non-zero high-frequency viscosity. It is assumed that relaxation spectrum is distributed according to the Spriggs law; temperature impact on the liquid rheology is described on the basis of the temperature-superposition principle and activation theory. The dispersion equation for the waveguide, considered as a thin-walled tube with polymeric solution, is obtained within a quasi-one-dimensional formulation. Results of the study illustrate the influence of temperature on sound propagation in the system.
Abstract: Analytical expressions of the current and angular errors, as well as the frequency characteristics of an induction converter describing the relation with its structural parameters, the core and winding characteristics are obtained. Based on estimation of the dependences obtained, a mathematical problem of parametric optimization is formulated which can successfully be used for investigating and diagnosing an induction converter.
Abstract: In recent years many finite elements have been
developed for plate bending analysis. The formulated elements are
based on the strain based approach. This approach leads to the
representation of the displacements by higher order polynomial terms
without the need for the introduction of additional internal and
unnecessary degrees of freedom. Good convergence can also be
obtained when the results are compared with those obtained from the
corresponding displacement based elements, having the same total
number of degrees of freedom. Furthermore, the plate bending
elements are free from any shear locking since they converge to the
Kirchhoff solution for thin plates contrarily for the corresponding
displacement based elements. In this paper the efficiency of the strain
based approach compared to well known displacement formulation is
presented. The results obtained by a new formulated plate bending
element based on the strain approach and Kirchhoff theory are
compared with some others elements. The good convergence of the
new formulated element is confirmed.
Abstract: The analysis and design of thin shell structures is a topic of interest in a variety of engineering applications. In structural mechanics problems the analyst seeks to determine the distribution of stresses throughout the structure to be designed. It is also necessary to calculate the displacements of certain points of the structure to ensure that specified allowable values are not exceeded. In this paper a comparative study between displacement and strain based finite elements applied to the analysis of some thin shell structures is presented. The results obtained from some examples show the efficiency and the performance of the strain based approach compared to the well known displacement formulation.
Abstract: Solid lipid nanoparticles (SLNs) have gained great attention for the topical treatment of skin associated fungal infection as they facilitate the skin penetration of loaded drugs. Our work deals with the preparation of nystatin loaded solid lipid nanoparticles (NystSLNs) using the hot homogenization and ultrasonication method. The prepared NystSLNs were characterized in terms of entrapment efficiency, particle size, zeta potential, transmission electron microscopy, differential scanning calorimetry, rheological behavior and in vitro drug release. A stability study for 6 months was performed. A microbiological study was conducted in male rats infected with Candida albicans, by counting the colonies and examining the histopathological changes induced on the skin of infected rats. The results showed that SLNs dispersions are spherical in shape with particle size ranging from 83.26±11.33 to 955.04±1.09 nm. The entrapment efficiencies are ranging from 19.73±1.21 to 72.46±0.66% with zeta potential ranging from -18.9 to -38.8 mV and shear-thinning rheological Behavior. The stability studies done for 6 months showed that nystatin (Nyst) is a good candidate for topical SLN formulations. A least number of colony forming unit/ ml (cfu/ml) was recorded for the selected NystSLN compared to the drug solution and the commercial Nystatin® cream present in the market. It can be fulfilled from this work that SLNs provide a good skin targeting effect and may represent promising carrier for topical delivery of Nyst offering the sustained release and maintaining the localized effect, resulting in an effective treatment of cutaneous fungal infection.
Abstract: Nanoscale thermites such as the composite mixture of
nano-sized aluminum and molybdenum trioxide powders possess
several technical advantages such as much higher reaction rate and
shorter ignition delay, when compared to the conventional energetic
formulations made of micron-sized metal and oxidizer particles. In this
study, the self-propagation of combustion wave in compacted pellets
of nanoscale thermite composites is modeled and computationally
investigated by utilizing the activation energy reduction of aluminum
particles due to nanoscale particle sizes. The present computational
model predicts the speed of combustion wave propagation which is
good agreement with the corresponding experiments of thermite
reaction. Also, several characteristics of thermite reaction in nanoscale
composites are discussed including the ignition delay and combustion
wave structures.
Abstract: The optimization of biological systems, which is a branch of metabolic engineering, has generated a lot of industrial and academic interest for a long time. In the last decade, metabolic engineering approaches based on mathematical optimizations have been used extensively for the analysis and manipulation of metabolic networks. In practical optimization of metabolic reaction networks, designers have to manage the nature of uncertainty resulting from qualitative characters of metabolic reactions, e.g., the possibility of enzyme effects. A deterministic approach does not give an adequate representation for metabolic reaction networks with uncertain characters. Fuzzy optimization formulations can be applied to cope with this problem. A fuzzy multi-objective optimization problem can be introduced for finding the optimal engineering interventions on metabolic network systems considering the resilience phenomenon and cell viability constraints. The accuracy of optimization results depends heavily on the development of essential kinetic models of metabolic networks. Kinetic models can quantitatively capture the experimentally observed regulation data of metabolic systems and are often used to find the optimal manipulation of external inputs. To address the issues of optimizing the regulatory structure of metabolic networks, it is necessary to consider qualitative effects, e.g., the resilience phenomena and cell viability constraints. Combining the qualitative and quantitative descriptions for metabolic networks makes it possible to design a viable strain and accurately predict the maximum possible flux rates of desired products. Considering the resilience phenomena in metabolic networks can improve the predictions of gene intervention and maximum synthesis rates in metabolic engineering. Two case studies will present in the conference to illustrate the phenomena.
Abstract: Perfectly suited for natural or man-made emergency and disaster management situations such as flood, earthquakes, tornadoes, or tsunami, multi-target search path planning for a team of rescue agents is known to be computationally hard, and most techniques developed so far come short to successfully estimate optimality gap. A novel mixed-integer linear programming (MIP) formulation is proposed to optimally solve the multi-target multi-agent discrete search and rescue (SAR) path planning problem. Aimed at maximizing cumulative probability of successful target detection, it captures anticipated feedback information associated with possible observation outcomes resulting from projected path execution, while modeling agent discrete actions over all possible moving directions. Problem modeling further takes advantage of network representation to encompass decision variables, expedite compact constraint specification, and lead to substantial problem-solving speed-up. The proposed MIP approach uses CPLEX optimization machinery, efficiently computing near-optimal solutions for practical size problems, while giving a robust upper bound obtained from Lagrangean integrality constraint relaxation. Should eventually a target be positively detected during plan execution, a new problem instance would simply be reformulated from the current state, and then solved over the next decision cycle. A computational experiment shows the feasibility and the value of the proposed approach.
Abstract: In this work we describe the preparation of NanoSilver/methylcellulose hydrogel containing silver nanoparticles (NPs) for topical bactericidal applications. Highly concentrated dispersion of silver NPs as high as of 5g/L of silver with diameter of 10nm was prepared by reduction of AgNO3 via strong reducing agent NaBH4. Silver NPs were stabilized by addition of sodium polyacrylate in order to prevent their aggregation at such high concentration. This way synthesized silver NPs were subsequently incorporated into methylcellulose suspension at elevated temperature resulting in formation of NanoSilver/methylcellulose hydrogel when temperature cooled down to laboratory conditions. In vitro antibacterial activity assay proved high bactericidal and fungicidal efficiency of silver NPs alone in the form of dispersion as well as in the form of hydrogel against broad spectrum of bacteria and yeasts including highly multiresistant strains such as methicillin-resistant Staphylococcus aureus. A very low concentrations of silver as low as 0.84mg/L Ag in as-prepared dispersion gave antibacterial performance. NanoSilver/methylcellulose hydrogel showed antibacterial action at the lowest used silver concentration equal to 25mg/L. Such prepared NanoSilver/methylcellulose hydrogel represent promising topical antimicrobial formulation for treatment of burns and wounds.
Abstract: The article describes an approach to build competence in research of Bachelor and Master, which is now an important feature of modern specialist in the field of engineering. We provide an example of methodical teaching methods with the research aspect, including the formulation of the problem, the method of conducting experiments, analysis of the results. Implementation of methods allows the student to better consolidate their knowledge and skills at the same time to get research. Knowledge on the part of the media requires some training in the subject area and teaching methods.