Abstract: Cisplatin (CIS) is one of the most effective an anticancer drug and also toxic to cells by activating oxidative stress. Oleuropein (OLE) has key role against oxidative stress in mammalian cells, but the role of this antioxidant in the toxicity of CIS remains unknown. The aim of the present study was to investigate the efficacy of OLE on CIS-induced liver damages in male rats. With this aim, male Sprague Dawley rats were randomly assigned to one of eight groups: Control group; the group treated with 7 mg/kg/day CIS; the groups treated with 50, 100 and 200 mg/kg/day OLE (i.p.); and the groups treated with OLE for three days starting at 24 h following CIS injection. After 4 days of injections, serum was provided to assess the blood AST, ALT and LDH values. The liver tissues were removed for histological, biochemical (TAC, TOS and MDA) and genotoxic evaluations. In the CIS treated group, the whole liver tissue showed significant histological changes. Also, CIS significantly increased both the incidence of oxidative stress and the induction of 8-hydroxy-deoxyguanosine (8-OH-dG). Moreover, the rats taking CIS have abnormal results on liver function tests. However, these parameters reached to the normal range after administration of OLE for 3 days. Finally, OLE demonstrated an acceptable high potential and was effective in attenuating CIS-induced liver injury. In this trial, the 200 mg/kg dose of OLE firstly appeared to induce the most optimal protective response.
Abstract: This paper treats a design of combined control of a
single phase power factor correction (PFC). The strategy of the
proposed control is based on two parts, the first, for the outer loop
(DC output regulated voltage), and the second govern the input
current of the converter in order to achieve a sinusoidal form in phase
with the grid voltage. Two kinds of regulators are used, Fuzzy
controller for the outer loop and predictive controller for the inner
loop. The controllers are verified and discussed through simulation
under MATLAB/Simulink platform. Also an experimental
confirmation is applied. Results present a high dynamic performance
under various parameters changes.
Abstract: This paper presents the findings of successful implementation of Business Process Reengineering (BPR) of cement dispatch activities in a cement manufacturing plant located in India. Simulation model was developed for the purpose of identifying and analyzing the areas for improvement. The company was facing a problem of low throughput rate and subsequent forced stoppages of the plant leading to a high production loss of 15000MT per month. It was found from the study that the present systems and procedures related to the in-plant logistics plant required significant changes. The major recommendations included process improvement at the entry gate, reducing the cycle time at the security gate and installation of an additional weigh bridge. This paper demonstrates how BPR can be implemented for improving the in-plant logistics process. Various recommendations helped the plant to increase its throughput by 14%.
Abstract: We assume an IoT-based smart-home environment where the on-off status of each of the electrical appliances including the room lights can be recognized in a real time by monitoring and analyzing the smart meter data. At any moment in such an environment, we can recognize what the household or the user is doing by referring to the status data of the appliances. In this paper, we focus on a smart-home service that is to activate a robot vacuum cleaner at right time by recognizing the user situation, which requires a situation-aware model that can distinguish the situations that allow vacuum cleaning (Yes) from those that do not (No). We learn as our candidate models a few classifiers such as naïve Bayes, decision tree, and logistic regression that can map the appliance-status data into Yes and No situations. Our training and test data are obtained from simulations of user behaviors, in which a sequence of user situations such as cooking, eating, dish washing, and so on is generated with the status of the relevant appliances changed in accordance with the situation changes. During the simulation, both the situation transition and the resulting appliance status are determined stochastically. To compare the performances of the aforementioned classifiers we obtain their learning curves for different types of users through simulations. The result of our empirical study reveals that naïve Bayes achieves a slightly better classification accuracy than the other compared classifiers.
Abstract: The aim of this article is to identify the measures
companies undertake in order to adapt to the environment as well as
discussing their diversity and effectiveness. The research methods
used in the study include an in-depth analysis of the literature and a
case study, which helps to illustrate the issue in question. Referring to
the concept of agility, which is firmly embedded in the theory of
strategic management and has been developed with the aim of
adapting to the environment and its changes, the paper first examines
different types of adaptation measures for companies. Then the issue
under discussion is illustrated with the example of the company
Hortimex. This company is an eminent representative of the world’s
leading manufacturers of food additives and ingredients. The
company was established in 1988 and is a family business, which in
practice means that it conducts business in a responsible manner,
observing the law and respecting the interests of society and the
environment. The company’s mission is to develop a market in
Poland for the products and solutions offered by their partners and to
share their knowledge of additives in food production and
consumption.
Abstract: This article considers the problems of economic growth
and Russian energy strategy. Also in this paper, the issues related to
the economic growth prospects of Russian were discussed. Russian
energy strategy without standing Russia`s stature in global energy
markets, at the current production and extraction rates, will not be able
to sustain its own production as well as fulfil its energy strategy.
Indeed, Russia’s energy sector suffers from a chronic lack of
investments which are necessary to modernize its energy supply
system. In recent years, especially since the international financial
crisis, Russia-EU energy cooperation has made substantive progress.
Recently the break-through progress has been made, resulting mainly
from long-term contributing factors between the countries and recent
international economic and political situation changes. Analytical
material presented in the article is intended for a more detailed or
substantive analysis related to foreign economic relations of the
countries and Russia as well.
Abstract: The power buck converter is the most widely used
DC/DC converter topology. They have a very large application area
such as DC motor drives, photovoltaic power system which require
fast transient responses and high efficiency over a wide range of load
current. This work proposes, the modelling of DC/DC power buck
converter using state-space averaging method and the current-mode
control using a proportional-integral controller. The efficiency of the
proposed model and control loop are evaluated with operating point
changes. The simulation results proved the effectiveness of the linear
model of DC/DC power buck converter.
Abstract: The rising demand for format-flexible packaging
machines is caused by current market changes. Increasing the formatflexibility
is a new goal for the packaging machine manufacturers’
product development process. There are no methodical or designorientated
tools for a comprehensive consideration of this target. This
paper defines the term format-flexibility in the context of packaging
machines and shows the state-of-the-art for improving the
changeover of production machines. The requirements for a new
approach and the concept itself will be introduced, and the method
elements will be explained. Finally, the use of the concept and the
result of the development of a format-flexible packaging machine
will be shown.
Abstract: Electro-osmosis in clayey soils and sediments, for
purposes of clay consolidation, dewatering, or cleanup, and electro
injection in porous media is widespread recent decades. It is
experimentally found that the chemical properties of porous media
especially PH change the characteristics of media. Electro-osmotic
conductivity is a function of soil and grout material chemistry,
altering with time. Many numerical approaches exist to simulate the
of electro kinetic flow rate considering chemical changes. This paper
presents a simplified analytical solution for constant flow rate based
on varying electro osmotic conductivity and time dependent viscosity
for injection of colloidal silica.
Abstract: Background modeling and subtraction in video
analysis has been widely used as an effective method for moving
objects detection in many computer vision applications. Recently, a
large number of approaches have been developed to tackle different
types of challenges in this field. However, the dynamic background
and illumination variations are the most frequently occurred problems
in the practical situation. This paper presents a favorable two-layer
model based on codebook algorithm incorporated with local binary
pattern (LBP) texture measure, targeted for handling dynamic
background and illumination variation problems. More specifically,
the first layer is designed by block-based codebook combining with
LBP histogram and mean value of each RGB color channel. Because
of the invariance of the LBP features with respect to monotonic
gray-scale changes, this layer can produce block wise detection results
with considerable tolerance of illumination variations. The pixel-based
codebook is employed to reinforce the precision from the output of the
first layer which is to eliminate false positives further. As a result, the
proposed approach can greatly promote the accuracy under the
circumstances of dynamic background and illumination changes.
Experimental results on several popular background subtraction
datasets demonstrate very competitive performance compared to
previous models.
Abstract: The change of conditions for production companies in
high-wage countries is characterized by the globalization of
competition and the transition of a supplier´s to a buyer´s market. The
companies need to face the challenges of reacting flexibly to these
changes. Due to the significant and increasing degree of automation,
assembly has become the most expensive production process.
Regarding the reduction of production cost, assembly consequently
offers a considerable rationalizing potential. Therefore, an
aerodynamic feeding system has been developed at the Institute of
Production Systems and Logistics (IFA), Leibniz Universitaet
Hannover. This system has been enabled to adjust itself by using a
genetic algorithm. The longer this genetic algorithm is executed the
better is the feeding quality. In this paper, the relation between the
system´s setting time and the feeding quality is observed and a
function which enables the user to achieve the minimum of the total
feeding time is presented.
Abstract: Broiler slaughter waste has become a major source of
pollution throughout the world. Utilization of broiler slaughter waste
by dry rendering process produced Rendered Chicken Oil (RCO), a
cheap raw material for biodiesel production and Carcass Meal a feed
ingredient for pets and fishes. Conversion of RCO into biodiesel may
open new vistas for generating wealth from waste besides controlling
the major havoc of environmental pollution. A two-step process to
convert RCO to good quality Biodiesel was invented. Acid catalysed
esterification of FFA followed by base catalysed transesterification of
triglycerides was carried out after meticulously standardizing the
methanol molar ratio, catalyst concentration, reaction temperature,
and reaction time to obtain the maximum biodiesel yield of 97.62%
and lowest glycerol yield of 6.96%. RCO biodiesel blend was tested
in a CRDI diesel engine. The results revealed that the blending of
commercial diesel with 20% RCO biodiesel (B20) lead to less engine
wear, a quieter engine and better fuel economy. The better lubricating
qualities of RCO B20 prevented over heating of engine, which
prolongs the engine life. RCO B20 can reduce the import of crude oil
and substantially reduce the engine emissions as proved by
significantly lower smoke levels, thus mitigating climatic changes.
Abstract: The education sector is constantly faced with rapid
changes in technologies in terms of ensuring that the curriculum is up
to date and in terms of making sure that students are aware of these
technological changes. This challenge can be seen as the motivation
for this study, which is to examine the factors affecting computing
students’ awareness of the latest Information Technologies (ICTs).
The aim of this study is divided into two sub-objectives which are:
the selection of relevant theories and the design of a conceptual
model to support it as well as the empirical testing of the designed
model. The first objective is achieved by a review of existing
literature on technology adoption theories and models. The second
objective is achieved using a survey of computing students in the four
universities of the KwaZulu-Natal province of South Africa. Data
collected from this survey is analyzed using Statistical package for
the Social Science (SPSS) using descriptive statistics, ANOVA and
Pearson correlations. The main hypothesis of this study is that there is
a relationship between the demographics and the prior conditions of
the computing students and their awareness of general ICT trends and
of Digital Switch Over (DSO) a new technology which involves the
change from analog to digital television broadcasting in order to
achieve improved spectrum efficiency. The prior conditions of the
computing students that were considered in this study are students’
perceived exposure to career guidance and students’ perceived
curriculum currency. The results of this study confirm that gender,
ethnicity, and high school computing course affect students’
perceived curriculum currency while high school location affects
students’ awareness of DSO. The results of this study also confirm
that there is a relationship between students prior conditions and their
awareness of general ICT trends and DSO in particular.
Abstract: Recent investigations have demonstrated the global
sea level rise due to climate change impacts. In this study, climate
changes study the effects of increasing water level in the strait of
Hormuz. The probable changes of sea level rise should be
investigated to employ the adaption strategies. The climatic output
data of a GCM (General Circulation Model) named CGCM3 under
climate change scenario of A1b and A2 were used. Among different
variables simulated by this model, those of maximum correlation
with sea level changes in the study region and least redundancy
among themselves were selected for sea level rise prediction by using
stepwise regression. One of models (Discrete Wavelet artificial
Neural Network) was developed to explore the relationship between
climatic variables and sea level changes. In these models, wavelet
was used to disaggregate the time series of input and output data into
different components and then ANN was used to relate the
disaggregated components of predictors and input parameters to each
other. The results showed in the Shahid Rajae Station for scenario
A1B sea level rise is among 64 to 75 cm and for the A2 Scenario sea
level rise is among 90 t0 105 cm. Furthermore, the result showed a
significant increase of sea level at the study region under climate
change impacts, which should be incorporated in coastal areas
management.
Abstract: This study was carried out for an underground subway station at Seoul Metro, Korea. The optimal set-points of the ventilation control system are determined every 3 hours, then, the ventilation controller adjusts the ventilation fan speed according to the optimal set-point changes. Compared to manual ventilation system which is operated irrespective of the OAQ, the IDP-based ventilation control system saves 3.7% of the energy consumption. Compared to the fixed set-point controller which is operated irrespective of the IAQ diurnal variation, the IDP-based controller shows better performance with a 2% decrease in energy consumption, maintaining the comfortable IAQ range inside the station.
Abstract: Latin America is probably the region with greater
social inequality, contrary to the amount of rights enshrined in their
constitutions. In the last decade of the twentieth century, the area
resulted in significant changes to democratization and constitutional
changes. Through low-key public policy, political leaders activated
participation in the culture of human rights. The struggle for social
rights in Latin America has been a constant regulation. His
consecration at the constitutional level has chained search
application. The constitutionalization and judicial protection of these
rights have been crucial in countries like Argentina, Venezuela, Peru
and Colombia. This paper presents an analytical view on the
constitutionalization of social rights in the Latin American context
and its justiciability.
Abstract: The purpose of this project is to propose a quick and
environmentally friendly alternative to measure the quality of oils
used in food industry. There is evidence that repeated and
indiscriminate use of oils in food processing cause physicochemical
changes with formation of potentially toxic compounds that can
affect the health of consumers and cause organoleptic changes. In
order to assess the quality of oils, non-destructive optical techniques
such as Interferometry offer a rapid alternative to the use of reagents,
using only the interaction of light on the oil. Through this project, we
used interferograms of samples of oil placed under different heating
conditions to establish the changes in their quality. These
interferograms were obtained by means of a Mach-Zehnder
Interferometer using a beam of light from a HeNe laser of 10mW at
632.8nm. Each interferogram was captured, analyzed and measured
full width at half-maximum (FWHM) using the software from
Amcap and ImageJ. The total of FWHMs was organized in three
groups. It was observed that the average obtained from each of the
FWHMs of group A shows a behavior that is almost linear, therefore
it is probable that the exposure time is not relevant when the oil is
kept under constant temperature. Group B exhibits a slight
exponential model when temperature raises between 373 K and 393
K. Results of the t-Student show a probability of 95% (0.05) of the
existence of variation in the molecular composition of both samples.
Furthermore, we found a correlation between the Iodine Indexes
(Physicochemical Analysis) and the Interferograms (Optical
Analysis) of group C. Based on these results, this project highlights
the importance of the quality of the oils used in food industry and
shows how Interferometry can be a useful tool for this purpose.
Abstract: Nowadays, the use of renewable energy sources has been increasingly great because of the cost increase and public demand for clean energy sources. One of the fastest growing sources is wind energy. In this paper, Wind Diesel Hybrid System (WDHS) comprising a Diesel Generator (DG), a Wind Turbine Generator (WTG), the Consumer Load, a Battery-based Energy Storage System (BESS), and a Dump Load (DL) is used. Voltage is controlled by Diesel Generator; the frequency is controlled by BESS and DL. The BESS elimination is an efficient way to reduce maintenance cost and increase the dynamic response. Simulation results with graphs for the frequency of Power System, active power, and the battery power are presented for load changes. The controlling parameters are optimized by using Imperialist Competitive Algorithm (ICA). The simulation results for the BESS/no BESS cases are compared. Results show that in no BESS case, the frequency control is more optimal than the BESS case by using ICA.
Abstract: The objective of this paper is to present the process of
change in management accounting in Romania, a former communist
country from Eastern Europe. In order to explain this process, we used
the contingency and institutional theories. We focused on the
following directions: the presentation of the scientific context and
motivation of this research and the case study. We presented the state
of the art in the process of change in the management accounting from
the international and national perspective. We also described the
evolution of management accounting in Romania in the context of
economic and political changes. An important moment was the fall of
communism in 1989. This represents a starting point for a new
economic environment and for new management accounting.
Accordingly, we developed a case study which presented this
evolution. The conclusion of our research was that the changes in the
management accounting system of the company analysed occurred in
the same time with the institutionalisation of some elements (e.g.
degree of competition, training and competencies in management
accounting). The management accounting system was modelled by the
contingencies specific to this company (e.g. environment, industry,
strategy).
Abstract: This study presented to reduce earthquake damage and
emergency rehabilitation of critical structures such as schools, hightech
factories, and hospitals due to strong ground motions associated
with climate changes. Regarding recent trend, a strong earthquake
causes serious damage to critical structures and then the critical
structure might be influenced by sequence aftershocks (or tsunami)
due to fault plane adjustments. Therefore, in order to improve seismic
performance of critical structures, retrofitted or strengthening study
of the structures under aftershocks sequence after emergency
rehabilitation of the structures subjected to strong earthquakes is
widely carried out. Consequently, this study used composite material
for emergency rehabilitation of the structure rather than concrete and
steel materials because of high strength and stiffness, lightweight,
rapid manufacturing, and dynamic performance. Also, this study was
to develop or improve the seismic performance or seismic retrofit of
critical structures subjected to strong ground motions and earthquake
aftershocks, by utilizing GFRP-Corrugated Infill Panels (GCIP).