Abstract: The Standard Penetration Test (SPT) is the most
common in situ test for soil investigations. On the other hand, the
Cone Penetration Test (CPT) is considered one of the best
investigation tools. Due to the fast and accurate results that can be
obtained it complaints the SPT in many applications like field
explorations, design parameters, and quality control assessments.
Many soil index and engineering properties have been correlated to
both of SPT and CPT. Various foundation design methods were
developed based on the outcome of these tests. Therefore it is vital to
correlate these tests to each other so that either one of the tests can be
used in the absence of the other, especially for preliminary evaluation
and design purposes.
The primary purpose of this study was to investigate the
relationships between the SPT and CPT for different type of sandy
soils in Florida. Data for this research were collected from number of
projects sponsored by the Florida Department of Transportation
(FDOT), six sites served as the subject of SPT-CPT correlations. The
correlations were established between the cone resistance (qc), sleeve
friction (fs) and the uncorrected SPT blow counts (N) for various
soils.
A positive linear relationship was found between qc, fs and N for
various sandy soils. In general, qc versus N showed higher
correlation coefficients than fs versus N. qc/N ratios were developed
for different soil types and compared to literature values, the results
of this research revealed higher ratios than literature values.
Abstract: Maturity models, used descriptively to explain
changes in reality or normatively to guide managers to make
interventions to make organizations more effective and efficient, are
based on the principles of statistical quality control and PDCA
continuous improvement (Plan, Do, Check, Act). Some frameworks
developed over the concept of maturity models include COBIT,
CMM, and ITIL.
This paper presents some limitations of traditional maturity
models, most of them related to the mechanistic and reductionist
principles over which those models are built. As systems theory helps
the understanding of the dynamics of organizations and
organizational change, the development of a systemic maturity model
can help to overcome some of those limitations.
This document proposes a systemic maturity model, based on a
systemic conceptualization of organizations, focused on the study of
the functioning of the parties, the relationships among them, and their
behavior as a whole. The concept of maturity from the system theory
perspective is conceptually defined as an emergent property of the
organization, which arises as a result of the degree of alignment and
integration of their processes. This concept is operationalized through
a systemic function that measures the maturity of organizations, and
finally validated by the measuring of maturity in some organizations.
For its operationalization and validation, the model was applied to
measure the maturity of organizational Governance, Risk and
Compliance (GRC) processes.
Abstract: Quality control helps industries in improvements of its
product quality and productivity. Statistical Process Control (SPC) is
one of the tools to control the quality of products that turning practice
in bringing a department of industrial engineering process under
control. In this research, the process control of a turning
manufactured at workshops machines. The varying measurements
have been recorded for a number of samples of a rice polished
cylinder obtained from a number of trials with the turning practice.
SPC technique has been adopted by the process is finally brought
under control and process capability is improved.
Abstract: A simple, accurate and precise direct spectrophotometric method has been developed for the determination of cefixime in tablets and capsules. The method is based on the reaction of cefixime with a mixture of potassium iodide and potassium iodate to form yellow coloured product in ethanol-distilled water medium at room temperature which absorbed maximally at 352 nm. The factors affecting the reaction product were carefully studied and optimized. The validation parameters based on International Conference on Harmonisation (ICH, USA) guidelines were followed. The effect of common excipients used as additives has been tested and the tolerance limit was calculated for the determination of cefixime. Beer’s law is obeyed in the concentration range of 4 – 24 ug mL-1 with apparent molar absorptivity of 1.52 × 104 L mol-1cm-1 and Sandell’s sensitivity of 0.033 ug/cm2/ 0.001 absorbance unit. The limits of detection and quantitation for the proposed method are 0.32 and 1.06 ug mL-1, respectively. The proposed method has been successfully applied for the determination of cefixime in pharmaceutical formulations. The results obtained by the proposed method were statistically compared with the reference method using t- and F- values and found no significant difference between the two methods. The proposed method can be used as an alternate method for routine quality control analysis of cefixime in pharmaceutical formulations.
Abstract: Biopharmaceuticals manufacturing is one of the major economic activities worldwide. Ninety-three percent of the workforce in a biomanufacturing environment concentrates in production-related areas. As a result, strategic collaborations between industry and academia are crucial to ensure the availability of knowledgeable workforce needed in an economic region to become competitive in biomanufacturing. In the past decade, our institution has been a key strategic partner with multinational biotechnology companies in supplying science and engineering graduates in the field of industrial biotechnology. Initiatives addressing all levels of the educational pipeline, from K-12 to college to continued education for company employees have been established along a ten-year span. The Amgen BioTalents Program was designed to provide undergraduate science and engineering students with training in biomanufacturing. The areas targeted by this educational program enhance their academic development, since these topics are not part of their traditional science and engineering curricula. The educational curriculum involved the process of producing a biomolecule from the genetic engineering of cells to the production of an especially targeted polypeptide, protein expression and purification, to quality control, and validation. This paper will report and describe the implementation details and outcomes of the first sessions of the program.
Abstract: Building code-related literature provides
recommendations on normalizing approaches to the calculation of
the dynamic properties of structures. Most building codes make a
distinction among types of structural systems, construction material,
and configuration through a numerical coefficient in the
expression for the fundamental period. The period is then used in
normalized response spectra to compute base shear. The typical
parameter used in simplified code formulas for the fundamental
period is overall building height raised to a power determined from
analytical and experimental results. However, reinforced concrete
buildings which constitute the majority of built space in less
developed countries pose additional challenges to the ones built with
homogeneous material such as steel, or with concrete under stricter
quality control. In the present paper, the particularities of reinforced
concrete buildings are explored and related to current methods of
equivalent static analysis. A comparative study is presented between
the Uniform Building Code, commonly used for buildings within
and outside the USA, and data from the Middle East used to model
151 reinforced concrete buildings of varying number of bays, number
of floors, overall building height, and individual story height. The
fundamental period was calculated using eigenvalue matrix
computation. The results were also used in a separate regression
analysis where the computed period serves as dependent variable,
while five building properties serve as independent variables. The
statistical analysis shed light on important parameters that simplified
code formulas need to account for including individual story height,
overall building height, floor plan, number of bays, and concrete
properties. Such inclusions are important for reinforced concrete
buildings of special conditions due to the level of concrete damage,
aging, or materials quality control during construction.
Overall results of the present analysis show that simplified code
formulas for fundamental period and base shear may be applied but
they require revisions to account for multiple parameters. The
conclusion above is confirmed by the analytical model where
fundamental periods were computed using numerical techniques and
eigenvalue solutions. This recommendation is particularly relevant
to code upgrades in less developed countries where it is customary to
adopt, and mildly adapt international codes.
We also note the necessity of further research using empirical data
from buildings in Lebanon that were subjected to severe damage due
to impulse loading or accelerated aging. However, we excluded this
study from the present paper and left it for future research as it has its
own peculiarities and requires a different type of analysis.
Abstract: In this paper, a low cost duty-cycle modulation scheme is studied in depth and compared to the standard pulse width modulation technique. Using a mix of analytical reasoning and electronics simulation tools, it is shown that under the same operating conditions, most characteristics of the proposed duty-cycle modulation scheme are better than those provided by a standard pulse width modulation technique. The simulation results obtained when testing both modulation control policies on prototyping systems, indicate that the proposed duty-cycle modulation approach, appears to be a high quality control policy in a wide variety of application areas, including A/D and D/A conversion, signal transmission and switching control in power electronics.
Abstract: The aim of the present study was to develop a rapid method for electronic nose for online quality control of oat milk. Analysis by electronic nose and bacteriological measurements were performed to analyze spoilage kinetics of oat milk samples stored at room temperature and refrigerated conditions for up to 15 days. Principal component analysis (PCA), Discriminant Factorial Analysis (DFA) and Soft Independent Modelling by Class Analogy (SIMCA) classification techniques were used to differentiate the samples of oat milk at different days. The total plate count (bacteriological method) was selected as the reference method to consistently train the electronic nose system. The e-nose was able to differentiate between the oat milk samples of varying microbial load. The results obtained by the bacteria total viable countsshowed that the shelf-life of oat milk stored at room temperature and refrigerated conditions were 20hrs and 13 days, respectively. The models built classified oat milk samples based on the total microbial population into “unspoiled” and “spoiled”.
Abstract: Pasta is one of the most widely consumed food products around the world. Rapid determination of the moisture content in pasta will assist food processors to provide online quality control of pasta during large scale production. Rapid Fourier transform near-infrared method (FT-NIR) was developed for determining moisture content in pasta. A calibration set of 150 samples, a validation set of 30 samples and a prediction set of 25 samples of pasta were used. The diffuse reflection spectra of different types of pastas were measured by FT-NIR analyzer in the 4,000-12,000cm-1 spectral range. Calibration and validation sets were designed for the conception and evaluation of the method adequacy in the range of moisture content 10 to 15 percent (w.b) of the pasta. The prediction models based on partial least squares (PLS) regression, were developed in the near-infrared. Conventional criteria such as the R2, the root mean square errors of cross validation (RMSECV), root mean square errors of estimation (RMSEE) as well as the number of PLS factors were considered for the selection of three pre-processing (vector normalization, minimum-maximum normalization and multiplicative scatter correction) methods. Spectra of pasta sample were treated with different mathematic pre-treatments before being used to build models between the spectral information and moisture content. The moisture content in pasta predicted by FT-NIR methods had very good correlation with their values determined via traditional methods (R2 = 0.983), which clearly indicated that FT-NIR methods could be used as an effective tool for rapid determination of moisture content in pasta. The best calibration model was developed with min-max normalization (MMN) spectral pre-processing (R2 = 0.9775). The MMN pre-processing method was found most suitable and the maximum coefficient of determination (R2) value of 0.9875 was obtained for the calibration model developed.
Abstract: One of the Best Management Practices (BMPs) promoted in Urban Stormwater Management Manual for Malaysia (MSMA) published by the Department of Irrigation and Drainage (DID) in 2001 is through the construction of wet ponds in new development projects for water quantity and quality control. Therefore, this paper aims to demonstrate a case study on evaluation of a constructed mini wet pond located at Sekolah Rendah Kebangsaan Seksyen 2, Puchong, Selangor, Malaysia in both stormwater quantity and quality aspect particularly to reduce the peak discharge by temporary storing and gradual release of stormwater runoff from an outlet structure or other release mechanism. The evaluation technique will be using InfoWorks Collection System (CS) as the numerical modeling approach for water quantity aspect. Statistical test by comparing the correlation coefficient (R2), mean error (ME), mean absolute error (MAE) and root mean square error (RMSE) were used to evaluate the model in simulating the peak discharge changes. Results demonstrated that there will be a reduction in peak flow at 11 % to 15% and time to peak flow is slower by 5 minutes through a wet pond. For water quality aspect, a survey on biological indicator of water quality carried out depicts that the pond is within the range of rather clean to clean water with the score of 5.3. This study indicates that a constructed wet pond with wetland facilities is able to help in managing water quantity and stormwater generated pollution at source, towards achieving ecologically sustainable development in urban areas.
Abstract: In Pharmaceutical industries, it is very important to remove drug residues from the equipment and areas used. The cleaning procedure must be validated, so special attention must be devoted to the methods used for analysis of trace amounts of drugs. A rapid, sensitive and specific reverse phase ultra performance liquid chromatographic (UPLC) method was developed for the quantitative determination of Albendazole in cleaning validation swab samples. The method was validated using an ACQUITY HSS C18, 50 x 2.1mm, 1.8μ column with a isocratic mobile phase containing a mixture of 1.36g of Potassium dihydrogenphosphate in 1000mL MilliQ water, 2mL of triethylamine and pH adjusted to 2.3 ± 0.05 with ortho-phosphoric acid, Acetonitrile and Methanol (50:40:10 v/v). The flow rate of the mobile phase was 0.5 mL min-1 with a column temperature of 350C and detection wavelength at 254nm using PDA detector. The injection volume was 2µl. Cotton swabs, moisten with acetonitrile were used to remove any residue of drug from stainless steel, teflon, rubber and silicon plates which mimic the production equipment surface and the mean extraction-recovery was found to be 91.8. The selected chromatographic condition was found to effectively elute Albendazole with retention time of 0.67min. The proposed method was found to be linear over the range of 0.2 to 150µg/mL and correlation coefficient obtained is 0.9992. The proposed method was found to be accurate, precise, reproducible and specific and it can also be used for routine quality control analysis of these drugs in biological samples either alone or in combined pharmaceutical dosage forms.
Abstract: Customer audits are generally used to ensure customer
that supplier is continuously able to meet his requirements while
supplying him required products and services. However, customer
audits can be considered as a very useful quality control tool for
suppliers as well. In our paper, we analyzed the process of customer
audits realized in Czech companies from both perspectives: a
supplier´s viewpoint and customer´s viewpoint. At the end, we tried
to emphasize some areas that should not be omitted during the audit
process.
Abstract: A new and cost effective RP-HPLC method was
developed and validated for simultaneous analysis of non steroidal
anti inflammatory dugs Diclofenac sodium (DFS), Flurbiprofen
(FLP) and an opioid analgesic Tramadol (TMD) in advanced drug
delivery systems (Liposome and Microcapsules), marketed brands
and human plasma. Isocratic system was employed for the flow of
mobile phase consisting of 10 mM sodium dihydrogen phosphate
buffer and acetonitrile in molar ratio of 67: 33 with adjusted pH of
3.2. The stationary phase was hypersil ODS column (C18, 250×4.6
mm i.d., 5 μm) with controlled temperature of 30 C°. DFS in
liposomes, microcapsules and marketed drug products was
determined in range of 99.76-99.84%. FLP and TMD in
microcapsules and brands formulation were 99.78 - 99.94 % and
99.80 - 99.82 %, respectively. Single step liquid-liquid extraction
procedure using combination of acetonitrile and trichloroacetic acid
(TCA) as protein precipitating agent was employed. The detection
limits (at S/N ratio 3) of quality control solutions and plasma samples
were 10, 20, and 20 ng/ml for DFS, FLP and TMD, respectively.
The Assay was acceptable in linear dynamic range. All other
validation parameters were found in limits of FDA and ICH method
validation guidelines. The proposed method is sensitive, accurate and
precise and could be applicable for routine analysis in
pharmaceutical industry as well as in human plasma samples for
bioequivalence and pharmacokinetics studies.
Abstract: Metrics is the process by which numbers or symbols
are assigned to attributes of entities in the real world in such a way as
to describe them according to clearly defined rules. Software metrics
are instruments or ways to measuring all the aspect of software
product. These metrics are used throughout a software project to
assist in estimation, quality control, productivity assessment, and
project control. Object oriented software metrics focus on
measurements that are applied to the class and other characteristics.
These measurements convey the software engineer to the behavior of
the software and how changes can be made that will reduce
complexity and improve the continuing capability of the software.
Object oriented software metric can be classified in two types static
and dynamic. Static metrics are concerned with all the aspects of
measuring by static analysis of software and dynamic metrics are
concerned with all the measuring aspect of the software at run time.
Major work done before, was focusing on static metric. Also some
work has been done in the field of dynamic nature of the software
measurements. But research in this area is demanding for more work.
In this paper we give a set of dynamic metrics specifically for
polymorphism in object oriented system.
Abstract: Over the years, there is a growing trend towards
quality-based specifications in highway construction. In many
Quality Control/Quality Assurance (QC/QA) specifications, the
contractor is primarily responsible for quality control of the process,
whereas the highway agency is responsible for testing the acceptance
of the product. A cooperative investigation was conducted in Illinois
over several years to develop a prototype End-Result Specification
(ERS) for asphalt pavement construction. The final characteristics of
the product are stipulated in the ERS and the contractor is given
considerable freedom in achieving those characteristics. The risk for
the contractor or agency depends on how the acceptance limits and
processes are specified. Stochastic simulation models are very useful
in estimating and analyzing payment risk in ERS systems and these
form an integral part of the Illinois-s prototype ERS system. This
paper describes the development of an innovative methodology to
estimate the variability components in in-situ density, air voids and
asphalt content data from ERS projects. The information gained from
this would be crucial in simulating these ERS projects for estimation
and analysis of payment risks associated with asphalt pavement
construction. However, these methods require at least two parties to
conduct tests on all the split samples obtained according to the
sampling scheme prescribed in present ERS implemented in Illinois.
Abstract: Quality control in ceramic tile manufacturing is hard, labor intensive and it is performed in a harsh industrial environment with noise, extreme temperature and humidity. It can be divided into color analysis, dimension verification, and surface defect detection, which is the main purpose of our work. Defects detection is still based on the judgment of human operators while most of the other manufacturing activities are automated so, our work is a quality control enhancement by integrating a visual control stage using image processing and morphological operation techniques before the packing operation to improve the homogeneity of batches received by final users.
Abstract: This purpose of this paper is to present the acceptance single sampling plan when the fraction of nonconforming items is a fuzzy number and being modeled based on the fuzzy Poisson distribution. We have shown that the operating characteristic (oc) curves of the plan is like a band having a high and low bounds whose width depends on the ambiguity proportion parameter in the lot when that sample size and acceptance numbers is fixed. Finally we completed discuss opinion by a numerical example. And then we compared the oc bands of using of binomial with the oc bands of using of Poisson distribution.
Abstract: The objective this study was to characterize and
develop anthropomorphic liver phantoms in tomography hepatic
procedures for quality control and improvement professionals in
nuclear medicine. For the conformation of the anthropomorphic
phantom was used in plaster and acrylic. We constructed three
phantoms representing processes with liver cirrhosis. The phantoms
were filled with 99mTc diluted with water to obtain the scintigraphic
images. Tomography images were analyzed anterior and posterior
phantom representing a body with a greater degree cirrhotic. It was
noted that the phantoms allow the acquisition of images similar to
real liver with cirrhosis. Simulations of hemangiomas may contribute
to continued professional education of nuclear medicine, on the
question of image acquisition, allowing of the study parameters such
of the matrix, energy window and count statistics.
Abstract: In this paper a novel method was presented for
evaluating the fabric pills using digital image processing techniques. This work provides a novel technique for
detecting pills and also measuring their heights, surfaces and
volumes. Surely, measuring the intensity of defects by human vision is an inaccurate method for quality control; as a result, this problem became a motivation for employing digital image processing techniques for detection of defects of fabric
surface. In the former works, the systems were just limited to measuring of the surface of defects, but in the presented
method the height and the volume of defects were also
measured, which leads to a more accurate quality control. An algorithm was developed to first, find pills and then measure their average intensity by using three criteria of height, surface
and volume. The results showed a meaningful relation
between the number of rotations and the quality of pilled fabrics.
Abstract: Since the beginning of human history, human
activities have caused many changes in the environment. Today, a
particular attention should be paid to gaining knowledge about water
quality of wetlands which are pristine natural environments rich in
genetic reserves. If qualitative conditions of industrial areas (in terms
of both physicochemical and biological conditions) are not addressed
properly, they could cause disruption in natural ecosystems,
especially in rivers. With regards to the quality of water resources,
determination of pollutant sources plays a pivotal role in engineering
projects as well as designing water quality control systems. Thus,
using different methods such as flow duration curves, dischargepollution
load model and frequency analysis by HYFA software
package, risk of various industrial pollutants in international and
ecologically important Gavkhoni wetland is analyzed. In this study, a
station located at Varzaneh City is used as the last station on
Zayanderud River, from where the river water is discharged into the
wetland. Results showed that elements- concentrations often
exceeded the allowed level and river water can endanger regional
ecosystem. In addition, if the river discharge is managed on Q25
basis, this basis can lower concentrations of elements, keeping them
within the normal level.