Abstract: Mobility, for many people, is an important factor in the satisfaction of daily needs and many people are dependent on public transport. In rural areas with a low population density, it is difficult to provide public transportation with sufficient coverage and frequency. Therefore, the available public transport is unattractive. As a result, people use their own car, which is not desirable from a sustainable point of view and not possible for children and elderly people. Sometimes people organize themselves and volunteer transport services are created. These services are similar to demand-oriented taxis. However, these transport services are usually independent from each other and from the available line-based public transport, limiting both their usability and sustainability. We have developed a platform to improve usability and sustainability by connecting the different demand-oriented transport offerings with the line-based public transport. The system was implemented and tested in a rural area in Germany, but the SARS-CoV-2 pandemic limited real live operation.
Abstract: Air transport links markets and individuals, promoting social and economic development. The review of management direction towards social responsibility and especially for the enhancement of passengers with autism is the key objective of this paper. According to a top-down approach, the key dimensions that affect the basic principles and directions of airport enterprises management towards social responsibility for the case of passengers with autism are presented. Conventional wisdom is to present actions undertaken in improving accessibility for special population groups and highlight the social dimension in the management of transport hubs. The target is to focus on transport hubs serving special groups of passengers such as passengers with autism and highlight good practices and motivate transport infrastructure management authorities and decision makers to promote the social footprint of transport. The highlights and key findings are essential for managers and decision makers to support actions and plans towards management of airport enterprises towards social responsibility, focusing on the case of passengers traveling with Autism Spectrum Disorder (ASD).
Abstract: Local generated and distributed system for thermal and electrical energy is sighted in the near future to reduce transmission losses instead of the centralized system. Distributed Energy Resources (DER) is designed at different sizes (small and medium) and it is incorporated in energy distribution between the hubs. The energy generated from each technology at each hub should meet the local energy demands. Economic and environmental enhancement can be achieved when there are interaction and energy exchange between the hubs. Network energy system and CO2 optimization between different six hubs presented Canadian community level are investigated in this study. Three different scenarios of technology systems are studied to meet both thermal and electrical demand loads for the six hubs. The conventional system is used as the first technology system and a reference case study. The conventional system includes boiler to provide the thermal energy, but the electrical energy is imported from the utility grid. The second technology system includes combined heat and power (CHP) system to meet the thermal demand loads and part of the electrical demand load. The third scenario has integration systems of CHP and Organic Rankine Cycle (ORC) where the thermal waste energy from the CHP system is used by ORC to generate electricity. General Algebraic Modeling System (GAMS) is used to model DER system optimization based on energy economics and CO2 emission analyses. The results are compared with the conventional energy system. The results show that scenarios 2 and 3 provide an annual total cost saving of 21.3% and 32.3 %, respectively compared to the conventional system (scenario 1). Additionally, Scenario 3 (CHP & ORC systems) provides 32.5% saving in CO2 emission compared to conventional system subsequent case 2 (CHP system) with a value of 9.3%.
Abstract: The brain’s functional connectivity while temporally non-stationary does express consistency at a macro spatial level. The study of stable resting state connectivity patterns hence provides opportunities for identification of diseases if such stability is severely perturbed. A mathematical model replicating the brain’s spatial connections will be useful for understanding brain’s representative geometry and complements the empirical model where it falls short. Empirical computations tend to involve large matrices and become infeasible with fine parcellation. However, the proposed analytical model has no such computational problems. To improve replicability, 92 subject data are obtained from two open sources. The proposed methodology, inspired by financial theory, uses multivariate regression to find relationships of every cortical region of interest (ROI) with some pre-identified hubs. These hubs acted as representatives for the entire cortical surface. A variance-covariance framework of all ROIs is then built based on these relationships to link up all the ROIs. The result is a high level of match between model and empirical correlations in the range of 0.59 to 0.66 after adjusting for sample size; an increase of almost forty percent. More significantly, the model framework provides an intuitive way to delineate between systemic drivers and idiosyncratic noise while reducing dimensions by more than 30 folds, hence, providing a way to conduct attribution analysis. Due to its analytical nature and simple structure, the model is useful as a standalone toolkit for network dependency analysis or as a module for other mathematical models.
Abstract: The wide-spread adoption of the Smart City concept has introduced a new era of computing paradigm with opportunities for city administrators and stakeholders in various sectors to re-think the concept of urbanization and development of healthy cities. With the world population rapidly becoming urban-centric especially amongst the emerging economies, social innovation will assist greatly in deploying emerging technologies to address the development challenges in core sectors of the future cities. In this context, sustainable health-care delivery and improved quality of life of the people is considered at the heart of the healthy city agenda. This paper examines the Boston innovation landscape from the perspective of smart services and innovation ecosystem for sustainable development, especially in transportation and healthcare. It investigates the policy implementation process of the Healthy City agenda and eHealth economy innovation based on the experience of Massachusetts’s City of Boston initiatives. For this purpose, three emerging areas are emphasized, namely the eHealth concept, the innovation hubs, and the emerging technologies that drive innovation. This was carried out through empirical analysis on results of public sector and industry-wide interviews/survey about Boston’s current initiatives and the enabling environment. The paper highlights few potential research directions for service integration and social innovation for deploying emerging technologies in the healthy city agenda. The study therefore suggests the need to prioritize social innovation as an overarching strategy to build sustainable Smart Cities in order to avoid technology lock-in. Finally, it concludes that the Boston example of innovation economy is unique in view of the existing platforms for innovation and proper understanding of its dynamics, which is imperative in building smart and healthy cities where quality of life of the citizenry can be improved.
Abstract: Wireless sensor networks can be tiny, low cost, intelligent sensors connected with advanced communication systems. WSNs have pulled in significant consideration as a matter of fact that, industrial as well as medical solicitations employ these in monitoring targets, conservational observation, obstacle exposure, movement regulator etc. In these applications, sensor hubs are thickly sent in the unattended environment with little non-rechargeable batteries. This constraint requires energy-efficient systems to drag out the system lifetime. There are redundancies in data sent over the network. To overcome this, multiple virtual spine scheduling has been presented. Such networks problems are called Maximum Lifetime Backbone Scheduling (MLBS) problems. Though this sleep wake cycle reduces radio usage, improvement can be made in the path in which the group heads stay selected. Cluster head selection with emphasis on geometrical relation of the system will enhance the load sharing among the nodes. Also the data are analyzed to reduce redundant transmission. Multi-hop communication will facilitate lighter loads on the network.
Abstract: Metabolomics has become a rising field of research
for various diseases, particularly cancer. Increases or decreases in
metabolite concentrations in the human body are indicative of various
cancers. Further elucidation of metabolic pathways and their
significance in cancer research may greatly spur medicinal discovery.
We analyzed the metabolomics profiles of lung cancer. Thirty-three
metabolites were selected as significant. These metabolites are
involved in 37 metabolic pathways delivered by MetaboAnalyst
software. The top pathways are glyoxylate and dicarboxylate
pathway (its hubs are formic acid and glyoxylic acid) along with
Citrate cycle pathway followed by Taurine and hypotaurine pathway
(the hubs in the latter are taurine and sulfoacetaldehyde) and Glycine,
serine, and threonine pathway (the hubs are glycine and L-serine). We
studied interactions of the metabolites with the proteins involved in
cancer-related signaling networks, and developed an approach to
metabolomics biomarker use in cancer diagnostics. Our analysis
showed that a significant part of lung-cancer-related metabolites
interacts with main cancer-related signaling pathways present in this
network: PI3K–mTOR–AKT pathway, RAS–RAF–ERK1/2 pathway,
and NFKB pathway. These results can be employed for use of
metabolomics profiles in elucidation of the related cancer proteins
signaling networks.
Abstract: Planning of infrastructure and processes in logistic
center within the frame of various kinds of logistic hubs and
technological activities in them represent quite complex problem.
The main goal is to design appropriate layout, which enables to
realize expected operation on the desired levels. The simulation
software represents progressive contemporary experimental
technique, which can support complex processes of infrastructure
planning and all of activities on it. It means that simulation
experiments, reflecting various planned infrastructure variants,
investigate and verify their eligibilities in relation with corresponding
expected operation. The inducted approach enables to make qualified
decisions about infrastructure investments or measures, which derive
benefit from simulation-based verifications. The paper represents
simulation software for simulation infrastructural layout and
technological activities in marshalling yard, intermodal terminal,
warehouse and combination between them as the parts of logistic
center.
Abstract: Web-based Cognitive Writing Instruction (WeCWI)’s
contribution towards language development can be divided into
linguistic and non-linguistic perspectives. In linguistic perspective,
WeCWI focuses on the literacy and language discoveries, while the
cognitive and psychological discoveries are the hubs in non-linguistic
perspective. In linguistic perspective, WeCWI draws attention to free
reading and enterprises, which are supported by the language
acquisition theories. Besides, the adoption of process genre approach
as a hybrid guided writing approach fosters literacy development.
Literacy and language developments are interconnected in the
communication process; hence, WeCWI encourages meaningful
discussion based on the interactionist theory that involves input,
negotiation, output, and interactional feedback. Rooted in the elearning
interaction-based model, WeCWI promotes online
discussion via synchronous and asynchronous communications,
which allows interactions happened among the learners, instructor,
and digital content. In non-linguistic perspective, WeCWI highlights
on the contribution of reading, discussion, and writing towards
cognitive development. Based on the inquiry models, learners’
critical thinking is fostered during information exploration process
through interaction and questioning. Lastly, to lower writing anxiety,
WeCWI develops the instructional tool with supportive features to
facilitate the writing process. To bring a positive user experience to
the learner, WeCWI aims to create the instructional tool with
different interface designs based on two different types of perceptual
learning style.
Abstract: We report a computational study of the spreading
dynamics of a viral infection in a complex (scale-free) network. The
final epidemic size distribution (FESD) was found to be unimodal or
bimodal depending on the value of the basic reproductive
number R0 . The FESDs occurred on time-scales long enough for
intermediate-time epidemic size distributions (IESDs) to be important
for control measures. The usefulness of R0 for deciding on the
timeliness and intensity of control measures was found to be limited
by the multimodal nature of the IESDs and by its inability to inform
on the speed at which the infection spreads through the population. A
reduction of the transmission probability at the hubs of the scale-free
network decreased the occurrence of the larger-sized epidemic events
of the multimodal distributions. For effective epidemic control, an
early reduction in transmission at the index cell and its neighbors was
essential.
Abstract: Environment both endowed and built are essential for
tourism. However tourism and environment maintains a complex
relationship, where in most cases environment is at the receiving end.
Many tourism development activities have adverse environmental
effects, mainly emanating from construction of general infrastructure
and tourism facilities. These negative impacts of tourism can lead to
the destruction of precious natural resources on which it depends.
These effects vary between locations; and its effect on a hill
destination is highly critical. This study aims at developing a
Sustainable Tourism Planning Model for an environmentally
sensitive tourism destination in Kerala, India. Being part of the
Nilgiri mountain ranges, Munnar falls in the Western Ghats, one of
the biological hotspots in the world. Endowed with a unique high
altitude environment Munnar inherits highly significant ecological
wealth. Giving prime importance to the protection of this ecological
heritage, the study proposes a tourism planning model with resource
conservation and sustainability as the paramount focus. Conceiving a
novel approach towards sustainable tourism planning, the study
proposes to assess tourism attractions using Ecological Sensitivity
Index (ESI) and Tourism Attractiveness Index (TAI). Integration of
these two indices will form the Ecology – Tourism Matrix (ETM),
outlining the base for tourism planning in an environmentally
sensitive destination. The ETM Matrix leads to a classification of
tourism nodes according to its Conservation Significance and
Tourism Significance. The spatial integration of such nodes based on
the Hub & Spoke Principle constitutes sub – regions within the STZ.
Ensuing analyses lead to specific guidelines for the STZ as a whole,
specific tourism nodes, hubs and sub-regions. The study results in a
multi – dimensional output, viz., (1) Classification system for tourism
nodes in an environmentally sensitive region/ destination (2)
Conservation / Tourism Development Strategies and Guidelines for
the micro and macro regions and (3) A Sustainable Tourism Planning
Tool particularly for Ecologically Sensitive Destinations, which can
be adapted for other destinations as well.
Abstract: Earlier studies in kinship networks have primarily
focused on observing the social relationships existing between family
relatives. In this study, we pre-identified hubs in the network to
investigate if they could play a catalyst role in the transfer of physical
information. We conducted a case study of a ceremony performed in
one of the families of a small Hindu community – the Uttar Rarhi
Kayasthas. Individuals (n = 168) who resided in 11 geographically
dispersed regions were contacted through our hub-based
representation. We found that using this representation, over 98% of
the individuals were successfully contacted within the stipulated
period. The network also demonstrated a small-world property, with
an average geodesic distance of 3.56.