Abstract: Topical photodynamic therapy (PDT) with
5-aminolevulinic acid (ALA) is an alternative therapy for treating
superficial cancer, especially for skin or oral cancer. ALA, a precursor
of the photosensitizer protoporphyrin IX (PpIX), is present as
zwitterions and hydrophilic property which make the low permeability
through the cell membrane. Collagen is a traditional carrier; its
molecular composed various amino acids which bear positive charge
and negative charge. In order to utilize the ion-pairs with ALA and
collagen, the study employed various pH values adjusting the net
charge. The aim of this study was to compare a series collagen form,
including solution, gel and sponge to investigate the topical delivery
behavior of ALA. The in vivo confocal laser scanning microscopy
(CLSM) study demonstrated that PpIX generation ability was different
pattern after apply for 6 h. Gel type could generate high PpIX, and
archived more deep of skin depth.
Abstract: Multi-agent system is composed by several agents
capable of reaching the goal cooperatively. The system needs an agent
platform for efficient and stable interaction between intelligent agents.
In this paper we propose a flexible and scalable agent platform by
composing the containers with multiple hierarchical agent groups. It
also allows efficient implementation of multiple domain presentations
of the agents unlike JADE. The proposed platform provides both
group management and individual management of agents for
efficiency. The platform has been implemented and tested, and it can
be used as a flexible foundation of the dynamic multi-agent system
targeting seamless delivery of ubiquitous services.
Abstract: Herein, we report the different types of surface morphology due to the interaction between the pure protein Insulin (INS) and catanionic surfactant mixture of Sodium Dodecyl Sulfate (SDS) and Cetyl Trimethyl Ammonium Bromide (CTAB) at air/water interface obtained by the Langmuir-Blodgett (LB) technique. We characterized the aggregations by Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM) and Fourier transform infrared spectroscopy (FTIR) in LB films. We found that the INS adsorption increased in presence of catanionic surfactant at air/water interface. The presence of small amount of surfactant induces two-stage growth kinetics due to the pure protein absorption and protein-catanionic surface micelle interaction. The protein remains in native state in presence of small amount of surfactant mixture. Smaller amount of surfactant mixture with INS is producing surface micelle type structure. This may be considered for drug delivery system. On the other hand, INS becomes unfolded and fibrillated in presence of higher amount of surfactant mixture. In both the cases, the protein was successfully immobilized on a glass substrate by the LB technique. These results may find applications in the fundamental science of the physical chemistry of surfactant systems, as well as in the preparation of drug-delivery system.
Abstract: Perth will run out of available sustainable natural
water resources by 2015 if nothing is done to slow usage rates,
according to a Western Australian study [1]. Alternative water
technology options need to be considered for the long-term
guaranteed supply of water for agricultural, commercial, domestic
and industrial purposes. Seawater is an alternative source of water for
human consumption, because seawater can be desalinated and
supplied in large quantities to a very high quality.
While seawater desalination is a promising option, the technology
requires a large amount of energy which is typically generated from
fossil fuels. The combustion of fossil fuels emits greenhouse gases
(GHG) and, is implicated in climate change. In addition to
environmental emissions from electricity generation for desalination,
greenhouse gases are emitted in the production of chemicals and
membranes for water treatment. Since Australia is a signatory to the
Kyoto Protocol, it is important to quantify greenhouse gas emissions
from desalinated water production.
A life cycle assessment (LCA) has been carried out to determine
the greenhouse gas emissions from the production of 1 gigalitre (GL)
of water from the new plant. In this LCA analysis, a new desalination
plant that will be installed in Bunbury, Western Australia, and known
as Southern Seawater Desalinization Plant (SSDP), was taken as a
case study. The system boundary of the LCA mainly consists of three
stages: seawater extraction, treatment and delivery. The analysis
found that the equivalent of 3,890 tonnes of CO2 could be emitted
from the production of 1 GL of desalinated water. This LCA analysis
has also identified that the reverse osmosis process would cause the
most significant greenhouse emissions as a result of the electricity
used if this is generated from fossil fuels
Abstract: Recent advances in wireless sensor networks have led
to many routing methods designed for energy-efficiency in wireless
sensor networks. Despite that many routing methods have been
proposed in USN, a single routing method cannot be energy-efficient
if the environment of the ubiquitous sensor network varies. We present
the controlling network access to various hosts and the services they
offer, rather than on securing them one by one with a network security
model. When ubiquitous sensor networks are deployed in hostile
environments, an adversary may compromise some sensor nodes and
use them to inject false sensing reports. False reports can lead to not
only false alarms but also the depletion of limited energy resource in
battery powered networks. The interleaved hop-by-hop authentication
scheme detects such false reports through interleaved authentication.
This paper presents a LMDD (Low energy method for data delivery)
algorithm that provides energy-efficiency by dynamically changing
protocols installed at the sensor nodes. The algorithm changes
protocols based on the output of the fuzzy logic which is the fitness
level of the protocols for the environment.
Abstract: Carbon nanotubes (CNTs) with their high mechanical,
electrical, thermal and chemical properties are regarded as promising
materials for many different potential applications. Having unique
properties they can be used in a wide range of fields such as
electronic devices, electrodes, drug delivery systems, hydrogen
storage, textile etc. Catalytic chemical vapor deposition (CCVD) is a
common method for CNT production especially for mass production.
Catalysts impregnated on a suitable substrate are important for
production with chemical vapor deposition (CVD) method. Iron
catalyst and MgO substrate is one of most common catalyst-substrate
combination used for CNT. In this study, CNTs were produced by
CCVD of acetylene (C2H2) on magnesium oxide (MgO) powder
substrate impregnated by iron nitrate (Fe(NO3)3•9H2O) solution. The
CNT synthesis conditions were as follows: at synthesis temperatures
of 500 and 800°C multiwall and single wall CNTs were produced
respectively. Iron (Fe) catalysts were prepared by with Fe:MgO ratio
of 1:100, 5:100 and 10:100. The duration of syntheses were 30 and
60 minutes for all temperatures and catalyst percentages. The
synthesized materials were characterized by thermal gravimetric
analysis (TGA), transmission electron microscopy (TEM) and Raman
spectroscopy.
Abstract: This paper describes the results and implications of a correlational study of learning styles and learner satisfaction. The relationship of these empirical concepts was examined in the context of traditional versus e-blended modes of course delivery in an introductory graduate research course. Significant results indicated that the visual side of the visual-verbal dimension of students- learning style(s) was positively correlated to satisfaction with themselves as learners in an e-blended course delivery mode and negatively correlated to satisfaction with the classroom environment in the context of a traditional classroom course delivery mode.
Abstract: In Algeria, liberalization reforms undertaken since the 1990s have resulted in negative effects on the development and management of irrigation schemes, as well as on the conditions of farmers. Reforms have been undertaken to improve the performance of irrigation schemes, such as the national plan of agricultural development (PNDA) in 2000 and the water pricing policy of 2005. However, after implementation of these policies, questions have arisen with regard to irrigation performance and its suitability for agricultural development. Hence, the aim of this paper is to provide insight into the profitability of irrigation during the transition period under current irrigation agricultural policies in Algeria. By using the method of farm crop budget analysis in the East Mitidja irrigation scheme, the returns from using surface water resources based on farm typology were found to vary among crops and farmers- groups within the scheme. Irrigation under the current situation is profitable for all farmers, including both those who benefit from subsidies and those who do not. However, the returns to water were found to be very sensitive to crop price fluctuations, particularly for non-subsidized groups and less so for those whose farming is based on orchards. Moreover, the socio-economic environment of the farmers contributed to less significant impacts of the PNDA policy. In fact, the limiting factor is not only the water, but also the lack of land ownership title. Market access constraints led to less agricultural investment and therefore to low intensification and low water productivity. It is financially feasible to recover the annual O&M costs in the irrigation scheme. By comparing the irrigation water price, returns to water, and O&M costs of water delivery, it is clear that irrigation can be profitable in the future. However, water productivity must be improved by enhancing farmers- income through farming investment, improving assets access, and the allocation of activities and crops which bring high returns to water; this could allow the farmers to pay more for water and allow cost recovery for water systems.
Abstract: The paper proposes a new concept in developing
collaborative design system. The concept framework involves
applying simulation of supply chain management to collaborative
design called – 'SCM–Based Design Tool'. The system is developed
particularly to support design activities and to integrate all facilities
together. The system is aimed to increase design productivity and
creativity. Therefore, designers and customers can collaborate by the
system since conceptual design. JAG: Jewelry Art Generator based
on artificial intelligence techniques is integrated into the system.
Moreover, the proposed system can support users as decision tool
and data propagation. The system covers since raw material supply
until product delivery. Data management and sharing information are
visually supported to designers and customers via user interface. The
system is developed on Web–assisted product development
environment. The prototype system is presented for Thai jewelry
industry as a system prototype demonstration, but applicable for
other industry.
Abstract: Mobile IP has been developed to provide the
continuous information network access to mobile users. In IP-based
mobile networks, location management is an important component of
mobility management. This management enables the system to track
the location of mobile node between consecutive communications. It
includes two important tasks- location update and call delivery.
Location update is associated with signaling load. Frequent updates
lead to degradation in the overall performance of the network and the
underutilization of the resources. It is, therefore, required to devise
the mechanism to minimize the update rate. Mobile IPv6 (MIPv6)
and Hierarchical MIPv6 (HMIPv6) have been the potential
candidates for deployments in mobile IP networks for mobility
management. HMIPv6 through studies has been shown with better
performance as compared to MIPv6. It reduces the signaling
overhead traffic by making registration process local. In this paper,
we present performance analysis of MIPv6 and HMIPv6 using an
analytical model. Location update cost function is formulated based
on fluid flow mobility model. The impact of cell residence time, cell
residence probability and user-s mobility is investigated. Numerical
results are obtained and presented in graphical form. It is shown that
HMIPv6 outperforms MIPv6 for high mobility users only and for low
mobility users; performance of both the schemes is almost equivalent
to each other.
Abstract: Routing security is a major concerned in Wireless
Sensor Network since a large scale of unattended nodes is deployed
in ad hoc fashion with no possibility of a global addressing due to a
limitation of node-s memory and the node have to be self organizing
when the systems require a connection with the other nodes. It
becomes more challenging when the nodes have to act as the router
and tightly constrained on energy and computational capabilities
where any existing security mechanisms are not allowed to be fitted
directly. These reasons thus increasing vulnerabilities to the network
layer particularly and to the whole network, generally. In this paper,
a Dynamic Window Secured Implicit Geographic Forwarding
(DWSIGF) routing is presented where a dynamic time is used for
collection window to collect Clear to Send (CTS) control packet in
order to find an appropriate hoping node. The DWIGF is expected to
minimize a chance to select an attacker as the hoping node that
caused by a blackhole attack that happen because of the CTS rushing
attack, which promise a good network performance with high packet
delivery ratios.
Abstract: This paper demonstrates how the soft systems
methodology can be used to improve the delivery of a module in data warehousing for fourth year information technology students.
Graduates in information technology needs to have academic skills
but also needs to have good practical skills to meet the skills requirements of the information technology industry. In developing
and improving current data warehousing education modules one has to find a balance in meeting the expectations of various role players such as the students themselves, industry and academia. The soft
systems methodology, developed by Peter Checkland, provides a
methodology for facilitating problem understanding from different world views. In this paper it is demonstrated how the soft systems methodology can be used to plan the improvement of data
warehousing education for fourth year information technology students.
Abstract: Access to information is the key to the empowerment of everybody despite where they are living. This research is to be carried out in respect of the people living in developing countries, considering their plight and complex geographical, demographic, social-economic conditions surrounding the areas they live, which hinder access to information and of professionals providing services such as medical workers, which has led to high death rates and development stagnation. Research on Unified Communications and Integrated Collaborations (UCIC) system in the health sector of developing countries comes in to create a possible solution of bridging the digital canyon among the communities. The aim is to deliver services in a seamless manner to assist health workers situated anywhere to be accessed easily and access information which will help in service delivery. The proposed UCIC provides the most immersive Telepresence experience for one-to-one or many-tomany meetings. Extending to locations anywhere in the world, the transformative platform delivers Ultra-low operating costs through the use of general purpose networks and using special lenses and track systems.
Abstract: Oxidative stress makes up common incidents in
eukaryotic metabolism. The presence of diverse components
disturbing the equilibrium during oxygen metabolism increases
oxidative damage unspecifically in living cells. Body´s own
ubiquinone (Q10) seems to be a promising drug in defending the
heightened appearance of reactive oxygen species (ROS). Though, its
lipophilic properties require a new strategy in drug formulation to
overcome their low bioavailability. Consequently, the manufacture of
heterogeneous nanodispersions is in focus for medical applications.
The composition of conventional nanodispersions is made up of a
drug-consisting core and a surfactive agent, also named as surfactant.
Long-termed encapsulation of the surfactive components into tissues
might be the consequence of the use during medical therapeutics. The
potential of provoking side-effects is given by their nonbiodegradable
properties. Further improvements during fabrication
process use the incorporation of biodegradable components such as
modified γ-polyglutamic acid which decreases the potential of
prospective side-effects.
Abstract: Many companies have switched their processes to project-oriented in the last years. This brings new possibilities and effectiveness not only in the field of external processes connected with the product delivery but also the internal processes as well. However centralized project organization which is based on the role of project manager in the team has proved insufficient in some cases. Agile methods of project organization are trying to solve this problem by bringing new view on the project organization, roles, processes and competences. Scrum is one of these methods which builds on the principles of knowledge management to drive the project to effectiveness from all view angles. Using this method to organize internal and delivery projects helps the organization to create and share knowledge throughout the company. It also supports forming unique competences of individuals and project teams and drives innovations in the company.
Abstract: The client server systems using mobile
communications networks for data transmission became very
attractive for many economic agents, in the purpose of promoting and
offering electronic services to their clients. E-services are suitable for
business developing and financial benefits increasing. The products
or services can be efficiently delivered to a large number of clients,
using mobile Internet access technologies. The clients can have
access to e-services, anywhere and anytime, with the support of 3G,
GPRS, WLAN, etc., channels bandwidth, data services and protocols.
Based on the mobile communications networks evolution and
development, a convergence of technological and financial interests
of mobile operators, software developers, mobile terminals producers
and e-content providers is established. These will lead to a high level
of integration of IT&C resources and will facilitate the value added
services delivery through the mobile communications networks. In
this paper it is presented a client server system, for e-services access,
with Smartphones and PDA-s mobile software applications, installed
on Symbian and Windows Mobile operating systems.
Abstract: Delay-Tolerant Networks (DTNs) are sparse, wireless
networks where disconnections are common due to host mobility and
low node density. The Message Ferrying (MF) scheme is a mobilityassisted
paradigm to improve connectivity in DTN-like networks. A
ferry or message ferry is a special node in the network which has
a per-determined route in the deployed area and relays messages
between mobile hosts (MHs) which are intermittently connected.
Increased contact opportunities among mobile hosts and the ferry
improve the performance of the network, both in terms of message
delivery ratio and average end-end delay. However, due to the inherent
mobility of mobile hosts and pre-determined periodicity of the
message ferry, mobile hosts may often -miss- contact opportunities
with a ferry. In this paper, we propose the combination of stationary
ferry access points (FAPs) with MF routing to increase contact
opportunities between mobile hosts and the MF and consequently
improve the performance of the DTN. We also propose several
placement models for deploying FAPs on MF routes. We evaluate the
performance of the FAP placement models through comprehensive
simulation. Our findings show that FAPs do improve the performance
of MF-assisted DTNs and symmetric placement of FAPs outperforms
other placement strategies.
Abstract: The paper proposes a new concept in developing
collaborative design system. The concept framework involves
applying simulation of supply chain management to collaborative
design called – 'SCM–Based Design Tool'. The system is developed
particularly to support design activities and to integrate all facilities
together. The system is aimed to increase design productivity and
creativity. Therefore, designers and customers can collaborate by the
system since conceptual design. JAG: Jewelry Art Generator based
on artificial intelligence techniques is integrated into the system.
Moreover, the proposed system can support users as decision tool
and data propagation. The system covers since raw material supply
until product delivery. Data management and sharing information are
visually supported to designers and customers via user interface. The
system is developed on Web–assisted product development
environment. The prototype system is presented for Thai jewelry
industry as a system prototype demonstration, but applicable for
other industry.
Abstract: Nowadays, power systems, energy generation by wind
has been very important. Noting that the production of electrical
energy by wind turbines on site to several factors (such as wind speed
and profile site for the turbines, especially off the wind input speed,
wind rated speed and wind output speed disconnect) is dependent. On
the other hand, several different types of turbines in the market there.
Therefore, selecting a turbine that its capacity could also answer the
need for electric consumers the efficiency is high something is
important and necessary. In this context, calculating the amount of
wind power to help optimize overall network, system operation, in
determining the parameters of wind power is very important.
In this article, to help calculate the amount of wind power plant,
connected to the national network in the region Manjil wind,
selecting the best type of turbine and power delivery profile
appropriate to the network using Monte Carlo method has been.
In this paper, wind speed data from the wind site in Manjil, as minute
and during the year has been. Necessary simulations based on
Random Numbers Simulation method and repeat, using the software
MATLAB and Excel has been done.
Abstract: Lean, which was initially developed by Toyota, is
widely implemented in other companies to improve competitiveness.
This research is an attempt to identify the adoption of lean in the
production system of Malaysian car manufacturer, Proton using case
study approach. To gain the in-depth information regarding lean
implementation, an activity on the assembly line called Set Parts
Supply (SPS) was studied. The result indicates that by using lean
principles, tools and techniques in the implementation of SPS enabled
to achieve the goals on safety, quality, cost, delivery and morale. The
implementation increased the size of the workspace, improved the
quality of assembly and the delivery of parts supply, reduced the
manpower, achieved cost savings on electricity and also increased the
motivation of manpower in respect of attendance at work. A
framework of SPS implementation is suggested as a contribution for
lean practices in production system.