Abstract: The present study explains the effect of aggregate
gradation on moisture damage in bituminous mixes. Three types of
aggregate gradation and two types of binder; VG-30 and Polymer
modified bitumen (PMB-40) are used. Moisture susceptibility tests
like retained stability and tensile strength ratio (TSR) and static creep
test are conducted on Marshall specimens. The creep test was also
conducted for conditioned and unconditioned specimens to observe
the effect of moisture on creep behaviour. The results indicate that
Marshall stability value is higher in PMB-40 mix than VG-30 mixes.
Moisture susceptibility of PMB-40 mixes is low when compared with
mix using VG-30. The reduction in retained stability, and indirect
tensile strength and increase in creep are evaluated for finer, coarser
and normal gradation of aggregate to observe the effect of gradation
on moisture susceptibility of mixes. The retained stability is least
affected when compared with other moisture susceptibility
parameters
Abstract: It is believed that DNA damaging toxic metabolites contributes to the development of different pathological conditions. To prevent harmful influence of toxic agents, cells developed number of protecting mechanisms, such as enzymatic reaction of detoxification of reactive metabolites and repair of DNA damage. The aim of the study was to examine the association between polymorphism of GSTT1/GSTM1 and XRCC1/3 genes and coronary artery disease (CAD) incidence. To examine a polymorphism of these genes in CAD susceptibility in patients and controls, PCR based genotyping assay was performed. For GST genes, frequency of GSTM1 null genotype among CAD affected group was significantly increased than in control group (P0.1). We found that neither XRCC1 Arg399Gln nor XRCC3 Thr241Met were associated with CAD risk. Obtained data suggests that GSTM1 null genotype carriers are more susceptible to CAD development.
Abstract: Finite element method was applied to model damage
development in the femoral neck during a sideways fall. The femoral
failure was simulated using the maximum principal strain criterion.
The evolution of damage was consistent with previous studies. It was
initiated by compressive failure at the junction of the superior aspect
of the femoral neck and the greater trochanter. It was followed by
tensile failure that occurred at the inferior aspect of the femoral neck
before a complete transcervical fracture was observed. The estimated
failure line was less than 50° from the horizontal plane (Pauwels type
II).
Abstract: The p53 tumor suppressor gene plays two important
roles in genomic stability: blocking cell proliferation after DNA
damage until it has been repaired, and starting apoptosis if the
damage is too critical. Codon 72 exon4 polymorphism (Arg72Pro) of
the P53 gene has been implicated in cancer risk. Various studies have
been done to investigate the status of p53 at codon 72 for arginine
(Arg) and proline (Pro) alleles in different populations and also the
association of this codon 72 polymorphism with various tumors. Our
objective was to investigate the possible association between P53
Arg72Pro polymorphism and susceptibility to colorectal cancer
among Isfahan and Chaharmahal Va Bakhtiari (a part of south west
of Iran) population. We investigated the status of p53 at codon 72 for
Arg/Arg, Arg/Pro and Pro/Pro allele polymorphisms in blood
samples from 145 colorectal cancer patients and 140 controls by
Nested-PCR of p53 exon 4 and digestion with BstUI restriction
enzyme and the DNA fragments were then resolved by
electrophoresis in 2% agarose gel. The Pro allele was 279 bp, while
the Arg allele was restricted into two fragments of 160 and 119 bp.
Among the 145 colorectal cancer cases 49 cases (33.79%) were
homozygous for the Arg72 allele (Arg/Arg), 18 cases (12.41%) were
homozygous for the Pro72 allele (Pro/Pro) and 78 cases (53.8%)
found in heterozygous (Arg/Pro).
In conclusion, it can be said that p53Arg/Arg genotype may be
correlated with possible increased risk of this kind of cancers in south
west of Iran.
Abstract: In the present article, effect of non-uniform excitation
of reservoir bottom on nonlinear response of concrete gravity dams is
considered. Anisotropic damage mechanics approach is used to model nonlinear behavior of mass concrete in 2D space. The tallest
monolith of Pine Flat dam is selected as a case study. The horizontal
and vertical components of 1967 Koyna earthquake is used to excite
the system. It is found that crest response and stresses within the dam body decrease significantly when the reservoir is excited nonuniformly. In addition, the crack profiles within the dam body and in vicinity of the neck decreases.
Abstract: The CMLP building was developed to be a model for
sustainability with strategies to reduce water, energy and pollution,
and to provide a healthy environment for the building occupants. The
aim of this paper is to investigate the environmental effects of energy
used by this building. A LCA (life cycle analysis) was led to measure
the real environmental effects produced by the use of energy. The
impact categories most affected by the energy use were found to be
the human health effects, as well as ecotoxicity. Natural gas
extraction, uranium milling for nuclear energy production, and the
blasting for mining and infrastructure construction are the processes
contributing the most to emissions in the human health effect. Data
comparing LCA results of CMLP building with a conventional
building results showed that energy used by the CMLP building has
less damage for the environment and human health than a
conventional building.
Abstract: Steel made pipelines with different diameters are used
for transmitting oil and gas which in many cases are buried in soil
under the sea bed or immersed in sea water. External corrosion of
pipes is an important form of deterioration due to the aggressive
environment of sea water. Corrosion normally results in pits. Hence,
using the finite element method, namely ABAQUS software, this
paper estimates the amount of pressure capacity reduction of a pipecontaining
a semi-elliptical pitting corrosion and the rate of corrosion
during the pipeline life of 25 years.
Abstract: The objective of this work is to present a expertise on
flooding hazard analysis and how to reduce the risk. The analysis
concerns the disaster induced by the flood on November 10/11, 2001
in the Bab El Oued district of the city of Algiers.The study begins by
an expertise of damages in related with the urban environment and
the history of the urban growth of the site. After this phase, the work
is focalized on the identification of the existing correlations between
the development of the town and its vulnerability. The final step
consists to elaborate the interpretations on the interactions between
the urban growth, the sewerage network and the vulnerability of the
urban system.In conclusion, several recommendations are formulated
permitting the mitigation of the risk in the future. The principal
recommendations concern the new urban operations and the existing
urbanized sites.
Abstract: Insect pests are the major source of crop
damage, yield and quality reduction in Pakistan and else
where in the world. Cotton crop is the most hit crop in
Pakistan followed by rice and the second most important
foreign exchange earning crop. A wide variety of staple,
horticultural and cash crops grown, reflect serious problems of
many types of insect pests. To overcome the insect pest
problem, pesticide use in Pakistan has increased substantially
which has now been further intensified. Pesticides worth more
than billions of rupees are imported every year. This paper
reviews the over all pesticide use in Pakistan in relation to
pesticide prices, support price of cotton and rice, pesticide use
in different provinces of Pakistan on different crops and their
impact on crop productivity. The environmental pollution
caused by the use of pesticides, contamination of soil and
water resources and the danger associated with the disposal of
their empty containers is also discussed in detail.
Abstract: Engineered nanoparticles’ usage rapidly increased in
various applications in the last decade due to their unusual properties.
However, there is an ever increasing concern to understand their
toxicological effect in human health. Particularly, metal and metal
oxide nanoparticles have been used in various sectors including
biomedical, food and agriculture. But their impact on human health is
yet to be fully understood. In this present investigation, we assessed
the toxic effect of engineered nanoparticles (ENPs) including Ag,
MgO and Co3O4 nanoparticles (NPs) on human mesenchymal stem
cells (hMSC) adopting cell viability and cellular morphological
changes as tools The results suggested that silver NPs are more toxic
than MgO and Co3O4NPs. The ENPs induced cytotoxicity and
nuclear morphological changes in hMSC depending on dose. The cell
viability decreases with increase in concentration of ENPs. The
cellular morphology studies revealed that ENPs damaged the cells.
These preliminary findings have implications for the use of these
nanoparticles in food industry with systematic regulations.
Abstract: The distressing flood scenarios that occur in
recent years at the surrounding areas of Sarawak River have
left damages of properties and indirectly caused disruptions of
productive activities. This study is meant to reconstruct a 100-year
flood event that took place in this river basin. Sarawak River Subbasin
was chosen and modeled using the one-dimensional
hydrodynamic modeling approach using InfoWorks River Simulation
(RS), in combination with Geographical Information System (GIS).
This produces the hydraulic response of the river and its floodplains
in extreme flooding conditions. With different parameters introduced
to the model, correlations of observed and simulated data are
between 79% – 87%. Using the best calibrated model, flood
mitigation structures are imposed along the sub-basin. Analysis is
done based on the model simulation results. Result shows that the
proposed retention ponds constructed along the sub-basin provide the
most efficient reduction of flood by 34.18%.
Abstract: In areas of low to moderate seismicity many building contents and equipment are not positively fixed to the floor or tied to adjacent walls. Under seismic induced horizontal vibration, such contents and equipment can suffer from damage by either overturning or impact associated with rocking. This paper focuses on the estimation of shock on typical contents and equipment due to rocking. A simplified analytical model is outlined that can be used to estimate the maximum acceleration on a rocking object given its basic geometric and mechanical properties. The developed model was validated against experimental results. The experimental results revealed that the maximum shock acceleration can be underestimated if the static stiffness of the materials at the interface between the rocking object and floor is used rather than the dynamic stiffness. Excellent agreement between the model and experimental results was found when the dynamic stiffness for the interface material was used, which was found to be generally much higher than corresponding static stiffness under different investigated boundary conditions of the cushion. The proposed model can be a beneficial tool in performing a rapid assessment of shock sensitive components considered for possible seismic rectification.
Abstract: In order to upgrade the seismic resistibility of structures and enhance the functionality of an isolator, a new base isolator called the multiple trench friction pendulum system (MTFPS) is proposed in this study. The proposed MTFPS isolator is composed of a trench concave surface and several intermediate sliding plates in two orthogonal directions. Mathematical formulations have been derived to examine the characteristics of the proposed MTFPS isolator possessing multiple intermediate sliding plates. By means of mathematical formulations, it can be inferred that the natural period and damping effect of the MTFPS isolator with several intermediate sliding plates can be altered continually and controllably during earthquakes. Furthermore, results obtained from shaking table tests demonstrate that the proposed isolator provides good protection to structures for prevention of damage from strong earthquakes.
Abstract: Irradiated material is a typical example of a complex
system with nonlinear coupling between its elements. During
irradiation the radiation damage is developed and this development
has bifurcations and qualitatively different kinds of behavior.
The accumulation of primary defects in irradiated crystals is
considered in frame work of nonlinear evolution of complex system.
The thermo-concentration nonlinear feedback is carried out as a
mechanism of self-oscillation development.
It is shown that there are two ways of the defect density evolution
under stationary irradiation. The first is the accumulation of defects;
defect density monotonically grows and tends to its stationary state
for some system parameters. Another way that takes place for
opportune parameters is the development of self-oscillations of the
defect density.
The stationary state, its stability and type are found. The
bifurcation values of parameters (environment temperature, defect
generation rate, etc.) are obtained. The frequency of the selfoscillation
and the conditions of their development is found and
rated. It is shown that defect density, heat fluxes and temperature
during self-oscillations can reach much higher values than the
expected steady-state values. It can lead to a change of typical
operation and an accident, e.g. for nuclear equipment.
Abstract: This work deals with the initial applications and formulation of an anisotropic plastic-damage constitutive model proposed for non-linear analysis of reinforced concrete structures submitted to a loading with change of the sign. The original constitutive model is based on the fundamental hypothesis of energy equivalence between real and continuous medium following the concepts of the Continuum Damage Mechanics. The concrete is assumed as an initial elastic isotropic medium presenting anisotropy, permanent strains and bimodularity (distinct elastic responses whether traction or compression stress states prevail) induced by damage evolution. In order to take into account the bimodularity, two damage tensors governing the rigidity in tension or compression regimes are introduced. Then, some conditions are introduced in the original version of the model in order to simulate the damage unilateral effect. The three-dimensional version of the proposed model is analyzed in order to validate its formulation when compared to micromechanical theory. The one-dimensional version of the model is applied in the analyses of a reinforced concrete beam submitted to a loading with change of the sign. Despite the parametric identification problems, the initial applications show the good performance of the model.
Abstract: Prickly pear fruit (Opuntia ficus indica L. Miller) belongs to the Cactaceae family. This species is very sensitive to low storage temperatures (< 5°C) which cause damages. The fruits can be peeled, suitably packaged and successfully commercialized as a ready-to-eat product. The main limit to the extension of the shelf life is the production of off-flavors due to different factors, the growth of microorganisms and the action of endogenous enzymes. Lipoxygenase (LOX) and Pectinesterase (PE) are involved in fruit degradation. In particular, LOX pathway is directly responsible for lipid oxidation, and the subsequent production of off-flavours, while PE causes the softening of fruit during maturation. They act on the texture and shelf-life of post-harvest, packaged fruits, as a function of the the grown of microorganisms and packaging technologies used. The aim of this work is to compare the effect of different packaging technologies on the shelf life extension of ready-to-eat prickly pear fruits with regards for the enzymes activities.
Abstract: Environmental impact assessment (EIA) is a procedure tool of environmental management for identifying, predicting, evaluating and mitigating the adverse effects of development proposals. EIA reports usually analyze how the amounts or concentrations of pollutants obey the relevant standards. Actually, many analytical tools can deepen the analysis of environmental impacts in EIA reports, such as life cycle assessment (LCA) and environmental risk assessment (ERA). Life cycle impact assessment (LCIA) is one of steps in LCA to introduce the causal relationships among environmental hazards and damage. Incorporating the LCIA concept into ERA as an integrated tool for EIA can extend the focus of the regulatory compliance of environmental impacts to determine of the significance of environmental impacts. Sometimes, when using integrated tools, it is necessary to consider fuzzy situations due to insufficient information; therefore, ERA should be generalized to fuzzy risk assessment (FRA). Finally, the use of the proposed methodology is demonstrated through the study case of the expansion plan of the world-s largest plastics processing factory.
Abstract: This paper describes a prototype aircraft that can fly
slowly, safely and transmit wireless video for tasks like reconnaissance,
surveillance and target acquisition. The aircraft is designed to
fly in closed quarters like forests, buildings, caves and tunnels which
are often spacious but GPS reception is poor. Envisioned is that a
small, safe and slow flying vehicle can assist in performing dull,
dangerous and dirty tasks like disaster mitigation, search-and-rescue
and structural damage assessment.
Abstract: Drought is one of the most important natural disasters which is probable to occur in all regions with completely different climates and in addition to causing death. It results in many economic losses and social consequences. For this reason. Studying the effects and losses caused by drought which include limitation or shortage of agricultural and drinking water resources. Decreased rainfall and increased evapotranspiration. Limited plant growth and decreased agricultural products. Especially those of dry-farming. Lower levels of surface and ground waters and increased immigrations. Etc. in the country is statistical period (1988-2007) for six stations in Roudbar town were used for statistical analysis and calculating humid and dry years. The dependable rainfall index (DRI) was the main method used in this research. Results showed that during the said statistical period and also during the years 1996-1998 and 2007. more than half of the stations had faced drought. With consideration of the conducted studies. Drawing diagrams and comparing the available data with those of dry and humid years it was found that drought affected agricultural products (e.g.olive) in a way that during the year 1996 1996 drought. Olive groves of Roudbar suffered the greatest damages. Whereupon about 70% of the crops were lost.
Abstract: This paper presents the results of preliminary
assessment of water quality along the coastal areas in the vicinity of
Left Bank Outfall Drainage (LBOD) and Tidal Link Drain (TLD) in
Sindh province after the cyclone 2A occurred in 1999. The water
samples were collected from various RDs of Tidal Link Drain and
lakes during September 2001 to April 2002 and were analysed for
salinity, nitrite, phosphate, ammonia, silicate and suspended material
in water. The results of the study showed considerable variations in
water quality depending upon the location along the coast in the
vicinity of LBOD and RDs. The salinity ranged between 4.39–65.25
ppt in Tidal Link Drain samples whereas 2.4–38.05 ppt in samples
collected from lakes. The values of suspended material at various
RDs of Tidal Link Drain ranged between 56.6–2134 ppm and at the
lakes between 68–297 ppm. The data of continuous monitoring at
RD–93 showed the range of PO4 (8.6–25.2 μg/l), SiO3 (554.96–1462
μg/l), NO2 (0.557.2–25.2 μg/l) and NH3 (9.38–23.62 μg/l). The
concentration of nutrients in water samples collected from different
RDs was found in the range of PO4 (10.85 to 11.47 μg/l), SiO3 (1624
to 2635.08 μg/l), NO2 (20.38 to 44.8 μg/l) and NH3 (24.08 to 26.6
μg/l). Sindh coastal areas which situated at the north-western
boundary the Arabian Sea are highly vulnerable to flood damages
due to flash floods during SW monsoon or impact of sea level rise
and storm surges coupled with cyclones passing through Arabian Sea
along Pakistan coast. It is hoped that the obtained data in this study
would act as a database for future investigations and monitoring of
LBOD and Tidal Link Drain coastal waters.