Abstract: Mushrooms are a group of fleshy macroscopic fungi.
They have been valued throughout the world as both edible and
medicine. They are highly nutritious with good amount of quality
proteins, vitamins and minerals. An edible mushroom, Calocybe
indica was selected to validate its nutritional and medicinal
properties. Since tissue damage in hyperglycemia has been related to
oxidative stress, we evaluated the enzymatic and non-enzymatic
antioxidant status in the serum, liver and kidney since they are the
target organs in diabetic complications. From the results, increased
oxidative stress and decreased antioxidants might be related to the
causation of diabetes mellitus. The treatment in the diabetic rats with
the Calocybe indica showed an increase in the antioxidant system
and decrease in the production of free radicals. The mushrooms
which contain antioxidant phytochemicals has potential free radical
scavenging capacity and hence can induce the antioxidant system in
the body significantly reduces the generated free radicals thereby
maintaining the normal levels of the antioxidants
Abstract: There is a growing interest in the food industry and in preventive health care for the development and evaluation of natural antioxidants from medicinal plant materials. In the present work, extracts of three medicinal plants (Tilia argentea, Crataegi folium leaves and Polygonum bistorta roots) used in Turkish phytotheraphy were screened for their phenolic profiles and antioxidant properties. Crude extracts were obtained from different parts of plants, by solidliquid extraction with pure water, 70% acetone and 70% methanol aqueous solvents. The antioxidant activity of the extracts was determined by ABTS.+ radical cation scavenging activity. The Folin Ciocalteu procedure was used to assess the total phenolic concentrations of the extracts as gallic acid equivalents. A modified liquid chromatography-electro spray ionization-mass spectrometry (LC-ESI-MS) was used to obtain chromatographic profiles of the phenolic compounds in the medicinal plants. The predominant phenolic compounds detected in different extracts of the plants were catechin, protocatechuic and chlorogenic acids. The highest phenolic contents were obtained by using 70% acetone as aqueous solvent, whereas the lowest phenolic contents were obtained by water extraction due to Folin Ciocalteu results. The results indicate that acetone extracts of Tilia argentea had the highest antioxidant capacity as free ABTS radical scavengers. The lowest phenolic contents and antioxidant capacities were obtained from Polygonum bistorta root extracts.
Abstract: In this paper we investigate numerically positive solutions of the equation -Δu = λuq+up with Dirichlet boundary condition in a boundary domain ╬® for λ > 0 and 0 < q < 1 < p < 2*, we will compute and visualize the range of λ, this problem achieves a numerical solution.
Abstract: This paper presents a novel algorithm for path planning of mobile robots in known 3D environments using Binary Integer Programming (BIP). In this approach the problem of path planning is formulated as a BIP with variables taken from 3D Delaunay Triangulation of the Free Configuration Space and solved to obtain an optimal channel made of connected tetrahedrons. The 3D channel is then partitioned into convex fragments which are used to build safe and short paths within from Start to Goal. The algorithm is simple, complete, does not suffer from local minima, and is applicable to different workspaces with convex and concave polyhedral obstacles. The noticeable feature of this algorithm is that it is simply extendable to n-D Configuration spaces.
Abstract: Dill contains range of phytochemicals, such as vitamin C and polyphenols, which significantly contribute to their total antioxidant activity. The aim of the current research was to determine the best blanching method for processing of dill prior to microwave vacuum drying based on the content of phenolic compounds, vitamin C and free radical scavenging activity. Two blanching mediums were used – water and steam, and for part of the samples microwave pretreatment was additionally used. Evaluation of vitamin C, phenolic contents and scavenging of DPPH˙ radical in dried dill was performed. Blanching had an effect on all tested parameters and the blanching conditions are very important. After evaluation of the results, as the best method for dill pretreatment was established blanching at 90 °C for 30 seconds.
Abstract: Horseradish (Armoracia rusticana) is a perennial herb belonging to the Brassicaceae family and contains biologically active substances. The aim of the current research was to determine best method for extraction of phenolic compounds from horseradish roots showing high antiradical activity. Three genotypes (No. 105; No. 106 and variety ‘Turku’) of horseradish roots were extracted with eight different solvents: n-hexane, ethyl acetate, diethyl ether, 2-propanol, acetone, ethanol (95%), ethanol / water / acetic acid (80/20/1 v/v/v) and ethanol / water (80/20 by volume) using two extraction methods (conventional and Soxhlet). As the best solvents ethanol and ethanol / water solutions can be chosen. Although in Soxhlet extracts TPC was higher, scavenging activity of DPPH˙ radicals did not increase. It can be concluded that using Soxhlet extraction method more compounds that are not effective antioxidants.
Abstract: Antioxidant activities of ethanolic extracts of Ardisia
japonica Blume., Ageartum conyzoides Linn., and Cocculus hirsutus
Linn Diels. leaves was determined qualitatively and quantitatively in
this research. 1, 1-diphenyl-2-picrylhydrazyl (DPPH) free radical
solution was used to investigate free radical scavenging activity of
these leaves extracts. Ascorbic acid (Vitamin C) was used as the
standard. In the present investigation, it is found that all of these
extracts have remarkable antioxidant activities. The EC50 values of
these ethanolic extracts were 12.72 μg/ml for A. japonica, 15.19
μg/ml for A. conyzoides, 10.68 μg/ml for C. hirsutus respectively.
Among these Myanmar medicinal plants, C. hirsutus showed higher
antioxidant activities as well as free radical scavenging activity than
black tea (Camellia sinensis), the famous antioxidant, and A.
japonica and A. conyzoides showed a rather lower antioxidant
activity than tea extracts. According to results from bioassay with
carrot discs infected with Agrobacterium tumefaciens, all extracts
showed anti-tumor activity after 3 weeks of incubation. No gall was
detected in carrot disks treated with C. hirsutus and A. japonica
extracts in the dose of 100ppm and in carrot discs treated with A.
conyzoides extract in the dose of 1000 ppm. Therefore, the research
clearly indicates that these weedy plants of dry farm land are
exceptionally advantageous for human health.
Abstract: This paper addresses issues of integral steering of
vehicles with two steering axles, where the rear wheels are pivoted in
the direction of the front wheels, but also in the opposite direction.
The steering box of the rear axle is presented with simple linkages
(single contour) that correlate the pivoting of the rear wheels
according to the direction of the front wheels, respectively to the
rotation angle of the steering wheel. The functionality of the system
is analyzed – the extent to which the requirements of the integral
steering are met by the considered/proposed mechanisms. The paper
highlights the quality of the single contour linkages, with two driving
elements for meeting these requirements, emphasizing diagrams of
mechanisms with 2 driving elements. Cam variants are analyzed and
proposed for the rear axle steering box. Cam profiles are determined
by various factors.
Abstract: This paper describes a computer-aided design for
design of the concave globoidal cam with cylindrical rollers and
swinging follower. Four models with different modeling methods are
made from the same input data. The input data are angular input and
output displacements of the cam and the follower and some other
geometrical parameters of the globoidal cam mechanism. The best
cam model is the cam which has no interference with the rollers
when their motions are simulated in assembly conditions. The
angular output displacement of the follower for the best cam is also
compared with that of in the input data to check errors. In this study,
Pro/ENGINEER® Wildfire 2.0 is used for modeling the cam,
simulating motions and checking interference and errors of the
system.
Abstract: The bioassay-guided isolation and purification of an
ethyl acetate extract of Aspergillus terreus MC751 led to the
characterization of butyrolactone I as an antidiabetic and antioxidant.
The antidiabetic activity of butyrolactone I was evaluated by α-
glucosidase and α-amylase inhibition assays. Butyrolactone I
demonstrated significant concentration-dependent, mixed-type
inhibitory activity against yeast α-glucosidase with an IC50 of 54μM.
However, the compound exhibited less activity against rat intestinal
α-glucosidase and α-amylase. This is the first report on α-glucosidase
inhibitory activity of butyrolactone I. The antioxidative activity of
butyrolactone I was evaluated based on scavenging effects on 1,1-
diphenyl-2-picrylhydrazyl (DPPH) (IC50 =51 μM) and hydrogen
peroxide (IC50= 141 μM) radicals as well as a reducing power assay.
The results suggest that butyrolactone I is a promising antidiabetic as
well as antioxidant and should be considered for clinical trials.
Abstract: Type 2 diabetes mellitus (T2DM) is a complex
metabolic disorder that characterized by the presence of high glucose
in blood that cause from insulin resistance and insufficiency due to
deterioration β-cell Langerhans functions. T2DM is commonly
caused by the combination of inherited genetic variations as well as
our own lifestyle. Metallothionein (MT) is a known cysteine-rich
protein responsible in helping zinc homeostasis which is important in
insulin signaling and secretion as well as protection our body from
reactive oxygen species (ROS). MT scavenged ROS and free
radicals in our body happen to be one of the reasons of T2DM and its
complications. The objective of this study was to investigate the
association of MT1A and MT2A polymorphisms between T2DM and
control subjects among Malay populations. This study involved 150
T2DM and 120 Healthy individuals of Malay ethnic with mixed
genders. The genomic DNA was extracted from buccal cells and
amplified for MT1A and MT2A loci; the 347bp and 238bp banding
patterns were respectively produced by mean of the Polymerase
Chain Reaction (PCR). The PCR products were digested with Mlucl
and Tsp451 restriction enzymes respectively and producing
fragments lengths of (158/189/347bp) and (103/135/238bp)
respectively. The ANOVA test was conducted and it shown that there
was a significant difference between diabetic and control subjects for
age, BMI, WHR, SBP, FPG, HBA1C, LDL, TG, TC and family
history with (P0.05). The genotype
frequency for AA, AG and GG of MT1A polymorphisms was 72.7%,
22.7% and 4.7% in cases and 15%, 55% and 30% in control
respectively. As for MT2A, genotype frequency of GG, GC and CC
was 42.7%, 27.3% and 30% in case and 5%, 40% and 55% for
control respectively. Both polymorphisms show significant difference
between two investigated groups with (P=0.000). The Post hoc test
was conducted and shows a significant difference between the
genotypes within each polymorphism (P=0. 000). The MT1A and
MT2A polymorphisms were believed to be the reliable molecular
markers to distinguish the T2DM subjects from healthy individuals in
Malay populations.
Abstract: This paper proposes the authentication method using
ESA algorithm instead of using CAVE algorithm in the CDMA
mobile communication systems including IS-95 and CDMA2000 1x.
And, we analyze to apply ESA mechanism on behalf of CAVE
mechanism without the change of message format and air interface in
the existing CDMA systems. If ESA algorithm can be used as the
substitution of CAVE algorithm, security strength of authentication
algorithm is intensified without protocol change. An algorithm
replacement proposed in this paper is not to change an authentication
mechanism, but to configure input of ESA algorithm and to produce
output. Therefore, our proposal can be the compatible to the existing
systems.
Abstract: Existing underground pipe jacking methods use a
reinforcing rod in a steel tube to obtain structural stiffness. However,
some problems such as inconvenience of works and expensive
materials resulted from limited working space and reinforcing works
are existed. To resolve these problems, a new pipe jacking method,
namely PST (Prestressed Segment Tunnel) method, was developed
which used joint to connect the steel segment and form erection
structure. For evaluating the flexural capacity of the PST method
structure, a experimental test was conducted. The parameters
considered in the test were span-to-depth ratio of segment, diameter of
steel tube at the corner, prestressing force, and welding of joint. The
flexural behaviours with the effect of load capacity in serviceability
state according to different parameters were examined.. The frame
with long segments could increase flexural stiffness and the specimen
with large diameter of concave corner showed excellent resistance
ability to the negative moment. In addition, welding of joints increased
the flexural capacity.
Abstract: Aloe vera has been used worldwide both for
pharmaceutical, food, and cosmetic industries due to the plethora of
biological activities of some of its metabolites. The aim of this study
was to evaluate the antifungal and antioxidant activities of the leaf
extract. The antifungal activity was determined by the agar-well
diffusion method against plant and human fungal pathogens. The
methanol and ethanol portions of the extracts studied were more
bioactive than ethyl acetate portion. It was also observed that the
activity was more pronounced on plant pathogen than human
pathogen except Candida albicans. This is an indication that the
extract has the potential to treat plant fungal infections. The Aloe
extract showed the significant antioxidant activity by the DPPH
radical scavenging method. Therefore, the Aloe extract provided as
natural antioxidant has been used in health foods for medical and
preservative purposes.
Abstract: The purpose of the present study is to analyze the
effect of the target plate-s curvature on the heat transfer in laminar
confined impinging jet flows. Numerical results from two
dimensional compressible finite volume solver are compared
between three different shapes of impinging plates: Flat, Concave
and Convex plates. The remarkable result of this study proves that
the stagnation Nusselt number in laminar range of Reynolds number
based on the slot width is maximum in convex surface and is
minimum in concave plate. These results refuse the previous data in
literature stating the amount of the stagnation Nusselt number is
greater in concave surface related to flat plate configuration.
Abstract: In order to upgrade the seismic resistibility of structures and enhance the functionality of an isolator, a new base isolator called the multiple trench friction pendulum system (MTFPS) is proposed in this study. The proposed MTFPS isolator is composed of a trench concave surface and several intermediate sliding plates in two orthogonal directions. Mathematical formulations have been derived to examine the characteristics of the proposed MTFPS isolator possessing multiple intermediate sliding plates. By means of mathematical formulations, it can be inferred that the natural period and damping effect of the MTFPS isolator with several intermediate sliding plates can be altered continually and controllably during earthquakes. Furthermore, results obtained from shaking table tests demonstrate that the proposed isolator provides good protection to structures for prevention of damage from strong earthquakes.
Abstract: We developed a vision interface immersive projection system, CAVE in virtual rea using hand gesture recognition with computer vis background image was subtracted from current webcam and we convert the color space of the imag Then we mask skin regions using skin color range t a noise reduction operation. We made blobs fro gestures were recognized using these blobs. Using recognition, we could implement an effective bothering devices for CAVE. e framework for an reality research field vision techniques. ent image frame age into HSV space. e threshold and apply from the image and ing our hand gesture e interface without
Abstract: This paper describes a prototype aircraft that can fly
slowly, safely and transmit wireless video for tasks like reconnaissance,
surveillance and target acquisition. The aircraft is designed to
fly in closed quarters like forests, buildings, caves and tunnels which
are often spacious but GPS reception is poor. Envisioned is that a
small, safe and slow flying vehicle can assist in performing dull,
dangerous and dirty tasks like disaster mitigation, search-and-rescue
and structural damage assessment.
Abstract: Chitosan is a biopolymer composed of glucosamine
and N-acetyl glucosamine. Solubility and viscosity pose problems in
some applications. These problems can be overcome with unique
modifications. In this study, firstly, chitosan was modified by caffeic
acid and thioglycolic acid, separately. Then, growing effects of these
modified polymers was observed in U937 cell line. Caffeic acid is a
phenolic compound and its modifications act carcinogenic inhibitors
in drugs. Thiolated chitosans are commonly being used for drugdelivery
systems in various routes, because of enhancing
mucoadhesiveness property. U937 cell line was used model cell for
leukaemia. Modifications were achieved by 1 – 15 % binding range.
Increasing binding ratios showed higher radical-scavenging activity
and reducing cell growth, in compared to native chitosan. Caffeic
acid modifications showed higher radical-scavenging activity than
thiolated chitosans at the same concentrations. Caffeic acid and
thioglycolic acid modifications inhibited growth of U937, effectively.
Abstract: Nigella sativa L. is an aromatic plant belonging to the
family Ranunculaceae. It has been used traditionally, especially in the
middle East and India, for the treatment of asthma, cough, bronchitis,
headache, rheumatism, fever, influenza and eczema. Several
biological activities have been reported in Nigella sativa seeds,
including antioxidant. In this context we tried to estimate the
antioxidant activity of various extracts prepared from Nigella sativa
seeds, methanolic extract (ME), chloroformic extract (CE), hexanic
extract (HE : fixed oil), ethyl acetate extract (EAE) water extract
(WE). The Folin-Ciocalteu assay showed that CE and EAE contained
high level of phenolic compounds 81.31 and 72.43μg GAE/mg of
extract respectively. Similarly, the CE and EAE exhibited the highest
DPPH radical scavenging activity, with IC50 values of 106.56μg/ml
and 121.62μg/ml respectively. In addition, CE and HE showed the
most scavenging activity against superoxide radical generated in the
PMS-NADH-NBT system with respective IC50 values of 361.86
μg/ml and 371.80 μg/ml, which is comparable to the activity of the
standard antioxidant BHT (344.59 μg/ml). Ferrous ion chelating
capacity assay showed that WE, EAE and ME are the most active
with 40.57, 39.70 and 22.02 mg EDTA-E/g of extract. The inhibition
of linoleic acid/ß-carotene coupled oxidation was estimated by ßcarotene
bleaching assay, this showed a highest relative antioxidant
activity with CE and EAE (69.82% of inhibition). The antioxidant
activities of the methanolic extract and the fixed oil are confirmed by
an in vivo assay in mice, the daily oral administration of methanolic
extract (500 and 800 mg/kg/day) and fixed oil (2 and 4 ml/kg/day)
during 21 days, resulted in a significant enhancement of the blood
total antioxidant capacity (measured by KRL test) and the plasmatic
antioxidant capacity towards DPPH radical.