Abstract: The PAX6, a transcription factor, is essential for the morphogenesis of the eyes, brain, pituitary and pancreatic islets. In rodents, the loss of Pax6 function leads to central nervous system defects, anophthalmia, and nasal hypoplasia. The haplo-insufficiency of Pax6 causes microphthalmia, aggression and other behavioral abnormalities. It is also required in brain patterning and neuronal plasticity. In human, heterozygous mutation of Pax6 causes loss of iris [aniridia], mental retardation and glucose intolerance. The 3- deletion in Pax6 leads to autism and aniridia. The phenotypes are variable in peneterance and expressivity. However, mechanism of function and interaction of PAX6 with other proteins during development and associated disease are not clear. It is intended to explore interactors of PAX6 to elucidated biology of PAX6 function in the tissues where it is expressed and also in the central regulatory pathway. This report describes In-silico approaches to explore interacting proteins of PAX6. The models show several possible proteins interacting with PAX6 like MITF, SIX3, SOX2, SOX3, IPO13, TRIM, and OGT. Since the Pax6 is a critical transcriptional regulator and master control gene of eye and brain development it might be interacting with other protein involved in morphogenesis [TGIF, TGF, Ras etc]. It is also presumed that matricelluar proteins [SPARC, thrombospondin-1 and osteonectin etc] are likely to interact during transport and processing of PAX6 and are somewhere its cascade. The proteins involved in cell survival and cell proliferation can also not be ignored.
Abstract: Natural disasters, including earthquake, kill many people around the world every year. Society rescue actions, which start after the earthquake and are called LAST in abbreviation, include locating, access, stabilization and transportation. In the present article, we have studied the process of local accessibility to the injured and transporting them to health care centers. With regard the heavy traffic load due to earthquake, the destruction of connecting roads and bridges and the heavy debris in alleys and street, which put the lives of the injured and the people buried under the debris in danger, accelerating the rescue actions and facilitating the accessibilities are of great importance, obviously. Tehran, the capital of Iran, is among the crowded cities in the world and is the center of extensive economic, political, cultural and social activities. Tehran has a population of about 9.5 millions and because of the immigration of people from the surrounding cities. Furthermore, considering the fact that Tehran is located on two important and large faults, a 6 Richter magnitude earthquake in this city could lead to the greatest catastrophe during the entire human history. The present study is a kind of review and a major part of the required information for it, has been obtained from libraries all of the rescue vehicles around the world, including rescue helicopters, ambulances, fire fighting vehicles and rescue boats, and their applied technology, and also the robots specifically designed for the rescue system and the advantages and disadvantages of them, have been investigated. The studies show that there is a significant relationship between the rescue team-s arrival time at the incident zone and the number of saved people; so that, if the duration of burial under debris 30 minutes, the probability of survival is %99.3, after a day is %81, after 2days is %19 and after 5days is %7.4. The exiting transport systems all have some defects. If these defects are removed, more people could be saved each hour and the preparedness against natural disasters is increased. In this study, transport system has been designed for the rescue team and the injured; which could carry the rescue team to the incident zone and the injured to the health care centers. In addition, this system is able to fly in the air and move on the earth as well; so that the destruction of roads and the heavy traffic load could not prevent the rescue team from arriving early at the incident zone. The system also has the equipment required firebird for debris removing, optimum transport of the injured and first aid.
Abstract: In this paper, two very different optimization
algorithms, Genetic and DIRECT algorithms, are used to history
match a bottomhole pressure response for a reservoir with wellbore
storage and skin with the best possible analytical model. No initial
guesses are available for reservoir parameters. The results show that
the matching process is much faster and more accurate for DIRECT
method in comparison with Genetic algorithm. It is furthermore
concluded that the DIRECT algorithm does not need any initial
guesses, whereas Genetic algorithm needs to be tuned according to
initial guesses.
Abstract: Recently, neural networks have shown good
results for detection of a certain pattern in a given image. In
our previous papers [1-5], a fast algorithm for pattern
detection using neural networks was presented. Such
algorithm was designed based on cross correlation in the
frequency domain between the input image and the weights
of neural networks. Image conversion into symmetric shape
was established so that fast neural networks can give the
same results as conventional neural networks. Another
configuration of symmetry was suggested in [3,4] to improve
the speed up ratio. In this paper, our previous algorithm for
fast neural networks is developed. The frequency domain
cross correlation is modified in order to compensate for the
symmetric condition which is required by the input image.
Two new ideas are introduced to modify the cross correlation
algorithm. Both methods accelerate the speed of the fast
neural networks as there is no need for converting the input
image into symmetric one as previous. Theoretical and
practical results show that both approaches provide faster
speed up ratio than the previous algorithm.
Abstract: A zero-field ferromagnetic Ising model is utilized to
simulate the propagation of infection in a population that assumes a
square lattice structure. The rate of infection increases with
temperature. The disease spreads faster among individuals with low J
values. Such effect, however, diminishes at higher temperatures.
Abstract: In the past many uneconomic solutions for limitation
and interruption of short-circuit currents in low power applications
have been introduced, especially polymer switch based on the
positive temperature coefficient of resistance (PCTR) concept.
However there are many limitations in the active material, which
consists of conductive fillers. This paper presents a significantly
improved and simplified approach that replaces the existing current
limiters with faster switching elements. Its elegance lies in the
remarkable simplicity and low-cost processes of producing the device
using polyaniline (PANI) doped with methane-sulfonic acid (MSA).
Samples characterized as lying in the metallic and critical regimes of
metal insulator transition have been studied by means of electrical
performance in the voltage range from 1V to 5 V under different
environmental conditions. Moisture presence is shown to increase the
resistivity and also improved its current limiting performance.
Additionally, the device has also been studied for electrical resistivity
in the temperature range 77 K-300 K. The temperature dependence of
the electrical conductivity gives evidence for a transport mechanism
based on variable range hopping in three dimensions.
Abstract: Modular multiplication is the basic operation
in most public key cryptosystems, such as RSA, DSA, ECC,
and DH key exchange. Unfortunately, very large operands
(in order of 1024 or 2048 bits) must be used to provide
sufficient security strength. The use of such big numbers
dramatically slows down the whole cipher system, especially
when running on embedded processors.
So far, customized hardware accelerators - developed on
FPGAs or ASICs - were the best choice for accelerating
modular multiplication in embedded environments. On the
other hand, many algorithms have been developed to speed
up such operations. Examples are the Montgomery modular
multiplication and the interleaved modular multiplication
algorithms. Combining both customized hardware with
an efficient algorithm is expected to provide a much faster
cipher system.
This paper introduces an enhanced architecture for computing
the modular multiplication of two large numbers X
and Y modulo a given modulus M. The proposed design is
compared with three previous architectures depending on
carry save adders and look up tables. Look up tables should
be loaded with a set of pre-computed values. Our proposed
architecture uses the same carry save addition, but replaces
both look up tables and pre-computations with an enhanced
version of sign detection techniques. The proposed architecture
supports higher frequencies than other architectures.
It also has a better overall absolute time for a single operation.
Abstract: System is using multiple processors for computing and information processing, is increasing rapidly speed operation of these systems compared with single processor systems, very significant impact on system performance is increased .important differences to yield a single multi-processor cpu, the scheduling policies, to reduce the implementation time of all processes. Notwithstanding the famous algorithms such as SPT, LPT, LSPT and RLPT for scheduling and there, but none led to the answer are not optimal.In this paper scheduling using genetic algorithms and innovative way to finish the whole process faster that we do and the result compared with three algorithms we mentioned.
Abstract: Flood zoning studies have become more efficient in
recent years because of the availability of advanced computational
facilities and use of Geographic Information Systems (GIS). In the
present study, flood inundated areas were mapped using GIS for the
Dikrong river basin of Arunachal Pradesh, India, corresponding to
different return periods (2, 5, 25, 50, and 100 years). Further, the developed inundation maps corresponding to 25, 50, and 100 year return period floods were compared to corresponding maps
developed by conventional methods as reported in the Brahmaputra Board Master Plan for Dikrong basin. It was found that, the average
deviation of modelled flood inundation areas from reported map
inundation areas is below 5% (4.52%). Therefore, it can be said that
the modelled flood inundation areas matched satisfactorily with
reported map inundation areas. Hence, GIS techniques were proved to be successful in extracting the flood inundation extent in a time and cost effective manner for the remotely located hilly basin of Dikrong, where conducting conventional surveys is very difficult.
Abstract: Background noise is particularly damaging to speech
intelligibility for people with hearing loss especially for sensorineural
loss patients. Several investigations on speech intelligibility have
demonstrated sensorineural loss patients need 5-15 dB higher SNR
than the normal hearing subjects. This paper describes Discrete
Cosine Transform Power Normalized Least Mean Square algorithm
to improve the SNR and to reduce the convergence rate of the LMS
for Sensory neural loss patients. Since it requires only real arithmetic,
it establishes the faster convergence rate as compare to time domain
LMS and also this transformation improves the eigenvalue
distribution of the input autocorrelation matrix of the LMS filter.
The DCT has good ortho-normal, separable, and energy compaction
property. Although the DCT does not separate frequencies, it is a
powerful signal decorrelator. It is a real valued function and thus
can be effectively used in real-time operation. The advantages of
DCT-LMS as compared to standard LMS algorithm are shown via
SNR and eigenvalue ratio computations. . Exploiting the symmetry
of the basis functions, the DCT transform matrix [AN] can be
factored into a series of ±1 butterflies and rotation angles. This
factorization results in one of the fastest DCT implementation. There
are different ways to obtain factorizations. This work uses the fast
factored DCT algorithm developed by Chen and company. The
computer simulations results show superior convergence
characteristics of the proposed algorithm by improving the SNR at
least 10 dB for input SNR less than and equal to 0 dB, faster
convergence speed and better time and frequency characteristics.
Abstract: This paper describes a research project on Year 3 primary school students in Malaysia in their use of computer-based video game to enhance learning of multiplication facts (tables) in the Mathematics subject. This study attempts to investigate whether video games could actually contribute to positive effect on children-s learning or otherwise. In conducting this study, the researchers assume a neutral stand in the investigation as an unbiased outcome of the study would render reliable response to the impact of video games in education which would contribute to the literature of technology-based education as well as impact to the pedagogical aspect of formal education. In order to conduct the study, a subject (Mathematics) with a specific topic area in the subject (multiplication facts) is chosen. The study adopts a causal-comparative research to investigate the impact of the inclusion of a computer-based video game designed to teach multiplication facts to primary level students. Sample size is 100 students divided into two i.e., A: conventional group and B conventional group aided by video games. The conventional group (A) would be taught multiplication facts (timetables) and skills conventionally. The other group (B) underwent the same lessons but with supplementary activity: a computer-based video game on multiplication which is called Timez-Attack. Analysis of marks accrued from pre-test will be compared to post- test using comparisons of means, t tests, and ANOVA tests to investigate the impact of computer games as an added learning activity. The findings revealed that video games as a supplementary activity to classroom learning brings significant and positive effect on students- retention and mastery of multiplication tables as compared to students who rely only upon formal classroom instructions.
Abstract: Teaching and learning about sustainability is a pedagogical endeavour with various innate difficulties and increased demands. Higher education has a dual role to play in addressing this challenge: to identify and explore innovative approaches and tools for addressing the complex and value-laden nature of sustainability in more meaningful ways, and to help teachers to integrate these approaches into their practice through appropriate professional development programs. The study reported here was designed and carried out within the context of a Masters course in Environmental Education. Eight teachers were collaboratively engaged in reconstructing a digital game microworld which was deliberately designed by the researchers to be questioned and evoke critical discussion on the idea of ‘sustainable city’. The study was based on the design-based research method. The findings indicate that the teachers’ involvement in processes of co-constructing the microworld initiated discussion and reflection upon the concepts of sustainability and sustainable lifestyles.
Abstract: The objective of this work is to present a expertise on
flooding hazard analysis and how to reduce the risk. The analysis
concerns the disaster induced by the flood on November 10/11, 2001
in the Bab El Oued district of the city of Algiers.The study begins by
an expertise of damages in related with the urban environment and
the history of the urban growth of the site. After this phase, the work
is focalized on the identification of the existing correlations between
the development of the town and its vulnerability. The final step
consists to elaborate the interpretations on the interactions between
the urban growth, the sewerage network and the vulnerability of the
urban system.In conclusion, several recommendations are formulated
permitting the mitigation of the risk in the future. The principal
recommendations concern the new urban operations and the existing
urbanized sites.
Abstract: Animation is simply defined as the sequencing of a
series of static images to generate the illusion of movement. Most
people believe that actual drawings or creation of the individual
images is the animation, when in actuality it is the arrangement of
those static images that conveys the motion. To become an animator,
it is often assumed that needed the ability to quickly design
masterpiece after masterpiece. Although some semblance of artistic
skill is a necessity for the job, the real key to becoming a great
animator is in the comprehension of timing. This paper will use a
combination of sprite animation, frame animation, and some other
techniques to cause a group of multi-colored static images to slither
around in the bounded area. In addition to slithering, the images
will also change the color of different parts of their body, much like
the real world creatures that have this amazing ability to change the
colors on their bodies do. This paper was implemented by using
Java 2 Standard Edition (J2SE).
It is both time-consuming and expensive to create animations,
regardless if they are created by hand or by using motion-capture
equipment. If the animators could reuse old animations and even
blend different animations together, a lot of work would be saved in
the process. The main objective of this paper is to examine a method
for blending several animations together in real time. This paper
presents and analyses a solution using Weighted Skeleton
Animation (WSA) resulting in limited CPU time and memory waste
as well as saving time for the animators. The idea presented is
described in detail and implemented. In this paper, text animation,
vertex animation, sprite part animation and whole sprite animation
were tested.
In this research paper, the resolution, smoothness and movement
of animated images will be carried out from the parameters, which
will be obtained from the experimental research of implementing
this paper.
Abstract: In this paper, an extended study is performed on the
effect of different factors on the quality of vector data based on a
previous study. In the noise factor, one kind of noise that appears in
document images namely Gaussian noise is studied while the previous
study involved only salt-and-pepper noise. High and low levels of
noise are studied. For the noise cleaning methods, algorithms that were
not covered in the previous study are used namely Median filters and
its variants. For the vectorization factor, one of the best available
commercial raster to vector software namely VPstudio is used to
convert raster images into vector format. The performance of line
detection will be judged based on objective performance evaluation
method. The output of the performance evaluation is then analyzed
statistically to highlight the factors that affect vector quality.
Abstract: Local Linear Neuro-Fuzzy Models (LLNFM) like other neuro- fuzzy systems are adaptive networks and provide robust learning capabilities and are widely utilized in various applications such as pattern recognition, system identification, image processing and prediction. Local linear model tree (LOLIMOT) is a type of Takagi-Sugeno-Kang neuro fuzzy algorithm which has proven its efficiency compared with other neuro fuzzy networks in learning the nonlinear systems and pattern recognition. In this paper, a dedicated reconfigurable and parallel processing hardware for LOLIMOT algorithm and its applications are presented. This hardware realizes on-chip learning which gives it the capability to work as a standalone device in a system. The synthesis results on FPGA platforms show its potential to improve the speed at least 250 of times faster than software implemented algorithms.
Abstract: This paper highlights the importance of integrating social and technical approach (which is so called a “hybrid socio-technical approach") as one innovative and strategic program to support the social development in geodisaster prone area in Indonesia. Such program mainly based on public education and community participation as a partnership program by the University, local government and may also with the private company and/ or local NGO. The indigenous, simple and low cost technology has also been introduced and developed as a part of the hybrid sociotechnical system, in order to ensure the life and environmental protection, with respect to the sustainable human and social development.
Abstract: Thermal load calculations have been performed for
multi-layered walls that are composed of three different parts; a
common (sand and cement) plaster, and two types of locally
produced soft and hard bricks. The masonry construction of these
layered walls was based on concrete-backed stone masonry made of
limestone bricks joined by mortar. These multilayered walls are
forming the outer walls of the building envelope of a typical Libyan
house. Based on the periodic seasonal weather conditions, within the
Libyan cost region during summer and winter, measured thermal
conductivity values were used to implement such seasonal variation
of heat flow and the temperature variations through the walls. The
experimental measured thermal conductivity values were obtained
using the Hot Disk technique. The estimation of the thermal
resistance of the wall layers ( R-values) is based on measurements
and calculations. The numerical calculations were done using a
simplified analytical model that considers two different wall
constructions which are characteristics of such houses. According to
the obtained results, the R-values were quite low and therefore,
several suggestions have been proposed to improve the thermal
loading performance that will lead to a reasonable human comfort
and reduce energy consumption.
Abstract: This paper tries to shed light on the existence of a bank lending channel (BLC) in South Eastern European countries (SEE). Based on a VAR framework we test the responsiveness of credit supply to monetary policy shocks. By compiling a new data set and using the reserve requirement ratio, among others, as the policy instrument we measure the effectiveness of the BLC and the buffering effect of the banks in the SEE countries. The results indicate that loan supply is significantly affected by shifts in monetary policy, when demand factors are controlled. Furthermore, by analyzing the effect of the Greek banks in the region we conclude that Greek banks do buffer the negative effects of monetary policy transmission. By having a significant market share of the SEE-s banking markets we argue that Greek banks influence positively the economic growth of SEE countries.
Abstract: This study carried out to determine the effect of plant
densities on some agronomic characteristics of four safflower cultivars in spring planting. The experiment was conducted at Yazd,
Iran- using a factorial in a randomized complete block design with four replications. Cultivars were including Arak, IL, Asteria and Local and plant densities were 10, 13.3, 20 and 40 plant/m2. Number
of seeds/head, number of heads/plant, HI, 1000-seed weight and seed yield significantly decreased as planting density increased. With increasing planting density, LAI, plant height, first branch height and
biological yield increased. The highest seed yield was obtained in 13.3 plant/m2 (2167 kg/ha). There were significant differences
between cultivars. Local cv. had higher seed yield than the other cultivars mainly due to higher heads/plant and seeds/head.