Abstract: This study presents a mathematical modeling approach to the planning of HIV therapies on an individual basis. The model replicates clinical data from typical-progressors to AIDS for all stages of the disease with good agreement. Clinical data from rapid-progressors and long-term non-progressors is also matched by estimation of immune system parameters only. The ability of the model to reproduce these phenomena validates the formulation, a fact which is exploited in the investigation of effective therapies. The therapy investigation suggests that, unlike continuous therapy, structured treatment interruptions (STIs) are able to control the increase in both the drug-sensitive and drug-resistant virus population and, hence, prevent the ultimate progression from HIV to AIDS. The optimization results further suggest that even patients characterised by the same progression type can respond very differently to the same treatment and that the latter should be designed on a case-by-case basis. Such a methodology is presented here.
Abstract: Testing is an activity that is required both in the
development and maintenance of the software development life cycle
in which Integration Testing is an important activity. Integration
testing is based on the specification and functionality of the software
and thus could be called black-box testing technique. The purpose of
integration testing is testing integration between software
components. In function or system testing, the concern is with overall
behavior and whether the software meets its functional specifications
or performance characteristics or how well the software and
hardware work together. This explains the importance and necessity
of IT for which the emphasis is on interactions between modules and
their interfaces. Software errors should be discovered early during
IT to reduce the costs of correction. This paper introduces a new type
of integration error, presenting an overview of Integration Testing
techniques with comparison of each technique and also identifying
which technique detects what type of error.
Abstract: In this study, an investigation over digestive diseases has been done in which the sound acts as a detector medium. Pursue to the preprocessing the extracted signal in cepstrum domain is registered. After classification of digestive diseases, the system selects random samples based on their features and generates the interest nonstationary, long-term signals via inverse transform in cepstral domain which is presented in digital and sonic form as the output. This structure is updatable or on the other word, by receiving a new signal the corresponding disease classification is updated in the feature domain.
Abstract: In this paper, we investigate the appearance of the giant component in random subgraphs G(p) of a given large finite graph family Gn = (Vn, En) in which each edge is present independently with probability p. We show that if the graph Gn satisfies a weak isoperimetric inequality and has bounded degree, then the probability p under which G(p) has a giant component of linear order with some constant probability is bounded away from zero and one. In addition, we prove the probability of abnormally large order of the giant component decays exponentially. When a contact graph is modeled as Gn, our result is of special interest in the study of the spread of infectious diseases or the identification of community in various social networks.
Abstract: Much time series data is generally from continuous dynamic system. Firstly, this paper studies the detection of the nonlinearity of time series from continuous dynamics systems by applying the Phase-randomized surrogate algorithm. Then, the Delay Vector Variance (DVV) method is introduced into nonlinearity test. The results show that under the different sampling conditions, the opposite detection of nonlinearity is obtained via using traditional test statistics methods, which include the third-order autocovariance and the asymmetry due to time reversal. Whereas the DVV method can perform well on determining nonlinear of Lorenz signal. It indicates that the proposed method can describe the continuous dynamics signal effectively.
Abstract: Rapid advancement in computing technology brings
computers and humans to be seamlessly integrated in future. The
emergence of smartphone has driven computing era towards
ubiquitous and pervasive computing. Recognizing human activity has
garnered a lot of interest and has raised significant researches-
concerns in identifying contextual information useful to human
activity recognition. Not only unobtrusive to users in daily life,
smartphone has embedded built-in sensors that capable to sense
contextual information of its users supported with wide range
capability of network connections. In this paper, we will discuss the
classification algorithms used in smartphone-based human activity.
Existing technologies pertaining to smartphone-based researches in
human activity recognition will be highlighted and discussed. Our
paper will also present our findings and opinions to formulate
improvement ideas in current researches- trends. Understanding
research trends will enable researchers to have clearer research
direction and common vision on latest smartphone-based human
activity recognition area.
Abstract: The aerodynamic noise radiation from a side view mirror (SVM) in the high-speed airflow is calculated by the combination of unsteady incompressible fluid flow analysis and acoustic analysis. The transient flow past the generic SVM is simulated with variable turbulence model, namely DES Detached Eddy Simulation and LES (Large Eddy Simulation). Detailed velocity vectors and contour plots of the time-varying velocity and pressure fields are presented along cut planes in the flow-field. Mean and transient pressure are also monitored at several points in the flow field and compared to corresponding experimentally data published in literature. The acoustic predictions made using the Ffowcs-Williams-Hawkins acoustic analogy (FW-H) and the boundary element (BEM).
Abstract: This paper considers the development of a two-point
predictor-corrector block method for solving delay differential
equations. The formulae are represented in divided difference form
and the algorithm is implemented in variable stepsize variable order
technique. The block method produces two new values at a single
integration step. Numerical results are compared with existing
methods and it is evident that the block method performs very well.
Stability regions of the block method are also investigated.
Abstract: This study examined the effects of eight weeks of
whole-body vibration training (WBVT) on vertical and decuple jump
performance in handball athletes. Sixteen collegiate Level I handball
athletes volunteered for this study. They were divided equally as
control group and experimental group (EG). During the period of the
study, all athletes underwent the same handball specific training, but
the EG received additional WBVT (amplitude: 2 mm, frequency: 20 -
40 Hz) three time per week for eight consecutive weeks. The vertical
jump performance was evaluated according to the maximum height of
squat jump (SJ) and countermovement jump (CMJ). Single factor
ANCOVA was used to examine the differences in each parameter
between the groups after training with the pretest values as a covariate.
The statistic significance was set at p < .05. After 8 weeks WBVT, the
EG had significantly improved the maximal height of SJ (40.92 ± 2.96
cm vs. 48.40 ± 4.70 cm, F = 5.14, p < .05) and the maximal height
CMJ (47.25 ± 7.48 cm vs. 52.20 ± 6.25 cm, F = 5.31, p < .05). 8 weeks
of additional WBVT could improve the vertical and decuple jump
performance in handball athletes. Enhanced motor unit
synchronization and firing rates, facilitated muscular contraction
stretch-shortening cycle, and improved lower extremity
neuromuscular coordination could account for these enhancements.
Abstract: Tensile armour wires provide a flexible pipe's
resistance to longitudinal stresses. Flexible pipe manufacturers need
to know the effect of defects such as scratches and cracks, with
dimensions less than 0.2mm which is the limit of the current nondestructive
detection technology, on the fracture stress and fracture
strain of the wire for quality assurance purposes. Recent research
involving the determination of the fracture strength of cracked wires
employed laboratory testing and classical fracture mechanics
approach using non-standardised fracture mechanics specimens
because standard test specimens could not be manufactured from the
wires owing to their sizes. In this work, the effect of miniature
cracks on the fracture properties of tensile armour wires was
investigated using laboratory and finite element tensile testing
simulations with the phenomenological shear fracture model. The
investigation revealed that the presence of cracks shallower than
0.2mm is worse on the fracture strain of the wire.
Abstract: Information and Communication Technologies (ICT) in mathematical education is a very active field of research and innovation, where learning is understood to be meaningful and grasping multiple linked representation rather than rote memorization, a great amount of literature offering a wide range of theories, learning approaches, methodologies and interpretations, are generally stressing the potentialities for teaching and learning using ICT. Despite the utilization of new learning approaches with ICT, students experience difficulties in learning concepts relevant to understanding mathematics, much remains unclear about the relationship between the computer environment, the activities it might support, and the knowledge that might emerge from such activities. Many questions that might arise in this regard: to what extent does the use of ICT help students in the process of understanding and solving tasks or problems? Is it possible to identify what aspects or features of students' mathematical learning can be enhanced by the use of technology? This paper will highlight the interest of the integration of information and communication technologies (ICT) into the teaching and learning of mathematics (quadratic functions), it aims to investigate the effect of four instructional methods on students- mathematical understanding and problem solving. Quantitative and qualitative methods are used to report about 43 students in middle school. Results showed that mathematical thinking and problem solving evolves as students engage with ICT activities and learn cooperatively.
Abstract: This paper presents a generalization kernel for gravitational
potential determination by harmonic splines. It was shown
in [10] that the gravitational potential can be approximated using a
kernel represented as a Newton integral over the real Earth body. On
the other side, the theory of geopotential approximation by harmonic
splines uses spherically oriented kernels. The purpose of this paper
is to show that in the spherical case both kernels have the same type
of representation, which leads us to conclusion that it is possible
to consider the kernel represented as a Newton integral over the real
Earth body as a kind of generalization of spherically harmonic kernels
to real geometries.
Abstract: It is observed that the Weighted least-square (WLS)
technique, including the modifications, results in equiripple error
curve. The resultant error as a percent of the ideal value is highly
non-uniformly distributed over the range of frequencies for which the
differentiator is designed. The present paper proposes a modification
to the technique so that the optimization procedure results in lower
maximum relative error compared to the ideal values. Simulation
results for first order as well as higher order differentiators are given
to illustrate the excellent performance of the proposed method.
Abstract: A concern that researchers usually face in different
applications of Artificial Neural Network (ANN) is determination of
the size of effective domain in time series. In this paper, trial and
error method was used on groundwater depth time series to determine
the size of effective domain in the series in an observation well in
Union County, New Jersey, U.S. different domains of 20, 40, 60, 80,
100, and 120 preceding day were examined and the 80 days was
considered as effective length of the domain. Data sets in different
domains were fed to a Feed Forward Back Propagation ANN with
one hidden layer and the groundwater depths were forecasted. Root
Mean Square Error (RMSE) and the correlation factor (R2) of
estimated and observed groundwater depths for all domains were
determined. In general, groundwater depth forecast improved, as
evidenced by lower RMSEs and higher R2s, when the domain length
increased from 20 to 120. However, 80 days was selected as the
effective domain because the improvement was less than 1% beyond
that. Forecasted ground water depths utilizing measured daily data
(set #1) and data averaged over the effective domain (set #2) were
compared. It was postulated that more accurate nature of measured
daily data was the reason for a better forecast with lower RMSE
(0.1027 m compared to 0.255 m) in set #1. However, the size of input
data in this set was 80 times the size of input data in set #2; a factor
that may increase the computational effort unpredictably. It was
concluded that 80 daily data may be successfully utilized to lower the
size of input data sets considerably, while maintaining the effective
information in the data set.
Abstract: This study examines perception of environmental
approach in small and medium-sized enterprises (SMEs) – the
process by which firms integrate environmental concern into
business. Based on a review of the literature, the paper synthesizes
focus on environmental issues with the reflection in a case study in
the Czech Republic. Two themes of corporate environmentalism are
discussed – corporate environmental orientation and corporate
stances toward environmental concerns. It provides theoretical
material on greening organizational culture that is helpful in
understanding the response of contemporary business to
environmental problems. We integrate theoretical predictions with
empirical findings confronted with reality. Scales to measure these
themes are tested in a survey of managers in 229 Czech firms. We
used the process of in-depth questioning. The research question was
derived and answered in the context of the corresponding literature
and conducted research. A case study showed us that environmental
approach is variety different (depending on the size of the firm) in
SMEs sector. The results of the empirical mapping demonstrate
Czech company’s approach to environment and define the problem
areas and pinpoint the main limitation in the expansion of
environmental aspects. We contribute to the debate for recognition of
the particular role of environmental issues in business reality.
Abstract: The presence of toxic heavy metals in industrial
effluents is one of the serious threats to the environment. Heavy
metals such as Cadmium, Chromium, Lead, Nickel, Zinc, Mercury,
Copper, Arsenic are found in the effluents of industries such as
foundries, electroplating, petrochemical, battery manufacturing,
tanneries, fertilizer, dying, textiles, metallurgical and metal finishing.
Tremendous increase of industrial copper usage and its presence in
industrial effluents has lead to a growing concern about the fate and
effects of Copper in the environment. Percolation of industrial
effluents through soils leads to contamination of ground water and
soils. The transport of heavy metals and their diffusion into the soils
has therefore, drawn the attention of the researchers.
In this study, an attempt has been made to delineate the
mechanisms of transport and fate of copper in terrestrial
environment. Column studies were conducted using perplex glass
square column of dimension side 15 cm and 1.35 m long. The soil
samples were collected from a natural drain near Mohali (India). The
soil was characterized to be poorly graded sandy loam. The soil was
compacted to the field dry density level of about 1.6 g/cm3. Break
through curves for different depths of the column were plotted. The
results of the column study indicated that the copper has high
tendency to flow in the soils and fewer tendencies to get absorbed on
the soil particles. The t1/2 estimates obtained from the studies can be
used for design copper laden wastewater disposal systems.
Abstract: Residue Number System (RNS) is a modular representation and is proved to be an instrumental tool in many digital signal processing (DSP) applications which require high-speed computations. RNS is an integer and non weighted number system; it can support parallel, carry-free, high-speed and low power arithmetic. A very interesting correspondence exists between the concepts of Multiple Valued Logic (MVL) and Residue Number Arithmetic. If the number of levels used to represent MVL signals is chosen to be consistent with the moduli which create the finite rings in the RNS, MVL becomes a very natural representation for the RNS. There are two concerns related to the application of this Number System: reaching the most possible speed and the largest dynamic range. There is a conflict when one wants to resolve both these problem. That is augmenting the dynamic range results in reducing the speed in the same time. For achieving the most performance a method is considere named “One-Hot Residue Number System" in this implementation the propagation is only equal to one transistor delay. The problem with this method is the huge increase in the number of transistors they are increased in order m2 . In real application this is practically impossible. In this paper combining the Multiple Valued Logic and One-Hot Residue Number System we represent a new method to resolve both of these two problems. In this paper we represent a novel design of an OHRNS-based adder circuit. This circuit is useable for Multiple Valued Logic moduli, in comparison to other RNS design; this circuit has considerably improved the number of transistors and power consumption.
Abstract: A novel circuit for generating a signal embedded with
features about data from three sensors is presented. This suggested
circuit is making use of a resistance-to-time converter employing a
bridge amplifier, an integrator and a comparator. The second resistive
sensor (Rz) is transformed into duty cycle. Another bridge with
varying resistor, (Ry) in the feedback of an OP AMP is added in
series to change the amplitude of the resulting signal in a proportional
relationship while keeping the same frequency and duty cycle
representing proportional changes in resistors Rx and Rz already
mentioned. The resultant output signal carries three types of
information embedded as variations of its frequency, duty cycle and
amplitude.
Abstract: The effects of divers carbon substrates were
investigated for the tabtoxin production of an isolated pathogenic
Pseudomonas syringae pv. tabaci, the causal agent of wildfire of
tobacco and are discussed in relation to the bacterium growth. The
isolated organism was grown in batch culture on Woolley's
medium (28°C, 200 rpm, during 5 days). The growth has been
measured by the optical density (OD) at 620 nm and the tabtoxin
production quantified by Escherichia coli (K-12) bioassay
technique. The growth and the tabtoxin production were both
influenced by the substrates (sugars, amino acids, organic acids)
used, each, as a sole carbon source and as a supplement for the
same amino acids. The most significant quantities of tabtoxin were
obtained in presence of some amino acids used as sole carbon
source and/or as supplement.
Abstract: This paper will discuss about an active power generator scheduling method in order to increase the limit level of steady state systems. Some power generator optimization methods such as Langrange, PLN (Indonesian electricity company) Operation, and the proposed Z-Thevenin-based method will be studied and compared in respect of their steady state aspects. A method proposed in this paper is built upon the thevenin equivalent impedance values between each load respected to each generator. The steady state stability index obtained with the REI DIMO method. This research will review the 500kV-Jawa-Bali interconnection system. The simulation results show that the proposed method has the highest limit level of steady state stability compared to other optimization techniques such as Lagrange, and PLN operation. Thus, the proposed method can be used to create the steady state stability limit of the system especially in the peak load condition.