Abstract: Medical methods to completely treat glaucoma are yet to be developed. Therefore, ophthalmologists manage patients mainly to delay disease progression. Patients with glaucoma are mainly elderly individuals. In elderly people's houses, having an equipment that can provide medical treatment and care can release their family from their care. For elderly people with the glaucoma to live by themselves as much as possible, we developed a support robot having five functions: elderly people care, ophthalmological examination, trip assistance to the neighborhood, medical treatment, and data referral to a hospital. The medical and nursing care robot should approach the visual field that the patients can see at a speed suitable for their eyesight. This is because the robot will be dangerous if it approaches the patients from the visual field that they cannot see. We experimentally developed a robot that brings a white cane to elderly people with glaucoma. The base part of the robot is a carriage, which is a Megarover 1.1, and it has two infrared sensors. The robot moves along a white line on the floor using the infrared sensors and has a special arm, which does not use electricity. The arm can scoop the block attached to the white cane. Next, we also developed a direction detector comprised of a charge-coupled device camera (SVR41ResucueHD; Sun Mechatronics), goggles (MG-277MLF; Midori Anzen Co. Ltd.), and biconvex lenses with a focal length of 25 mm (Edmund Co.). Some young people were photographed using the direction detector, which was put on their faces. Image processing was performed using Scilab 6.1.0 and Image Processing and Computer Vision Toolbox 4.1.2. To measure the people's line of vision, we calculated the iris's center of gravity using five processes: reduction, trimming, binarization or gray scale, edge extraction, and Hough transform. We compared the binarization and gray scale processes in image processing. The binarization process was better than the gray scale process. For edge extraction, we compared five methods: Sobel, Prewitt, Laplacian of Gaussian, fast Fourier transform, and Canny. The Canny method was the optimal extraction method. We performed the Hough transform to search for the main coordinates from the iris's edge, and we found that the Hough transform could calculate the center point of the iris.
Abstract: In this paper, a team of faculty members of the Petroleum Institute in Abu Dhabi, UAE representing six different courses across General Engineering (ENGR), Communication (COMM), and Design (STPS) worked together to establish a clear developmental progression of learning outcomes and performance indicators for targeted knowledge, areas of competency, and skills for the first three semesters of the Bachelor of Sciences in Engineering curriculum. The sequences of courses studied in this project were ENGR/COMM, COMM/STPS, and ENGR/STPS. For each course’s nine areas of knowledge, competency, and skills, the research team reviewed the existing learning outcomes and related performance indicators with a focus on identifying linkages across disciplines as well as within the courses of a discipline. The team reviewed existing performance indicators for developmental progression from semester to semester for same discipline related courses (vertical alignment) and for different discipline courses within the same semester (horizontal alignment). The results of this work have led to recommendations for modifications of the initial indicators when incoherence was identified, and/or for new indicators based on best practices (identified through literature searches) when gaps were identified. It also led to recommendations for modifications of the level of emphasis within each course to ensure developmental progression. The exercise has led to a revised Sequence Performance Indicator Mapping for the knowledge, skills, and competencies across the six core courses.
Abstract: The microstructure characterization of tempered nanocrystalline bainitic steel is investigated in the present study. It is found that two types of plastic relaxation, dislocation debris and nanotwin, occurs in the displacive transformation due to relatively low transformation temperature and high carbon content. Because most carbon atoms trap in the dislocation, high dislocation density can be sustained during the tempering process. More carbides only can be found in the high tempered temperature due to intense recovery progression.
Abstract: This study explores the clinical features of neurodegenerative disease patients with tremor. We study the motor impairments in patients with Parkinson’s disease (PD) and essential tremor (ET). Since uncertainty exists on whether Parkinson's disease (PD) and essential tremor (ET) patients have similar degree of impairment during motor tasks, this study based on the self-developed computerized handwriting movement analysis to characterize motor functions of these two impairments. The recruited subjects were diagnosed and confirmed one of neurodegenerative diseases. They were undergone general clinical evaluations by physicians in the first year. We recruited 8 participants with PD and 10 with ET. Additional 12 participants without any neuromuscular dysfunction were recruited as control group. This study used fine motor control of penmanship on digital tablet for sensorimotor function tests. The movement speed in PD/ET group is found significant slower than subjects in normal control group. In movement intensity and speed, the result found subject with ET has similar clinical feature with PD subjects. The ET group shows smaller and slower movements than control group but not to the same extent as PD group. The results of this study contribute to the early screening and detection of diseases and the evaluation of disease progression.
Abstract: This study presents a mathematical modeling approach to the planning of HIV therapies on an individual basis. The model replicates clinical data from typical-progressors to AIDS for all stages of the disease with good agreement. Clinical data from rapid-progressors and long-term non-progressors is also matched by estimation of immune system parameters only. The ability of the model to reproduce these phenomena validates the formulation, a fact which is exploited in the investigation of effective therapies. The therapy investigation suggests that, unlike continuous therapy, structured treatment interruptions (STIs) are able to control the increase in both the drug-sensitive and drug-resistant virus population and, hence, prevent the ultimate progression from HIV to AIDS. The optimization results further suggest that even patients characterised by the same progression type can respond very differently to the same treatment and that the latter should be designed on a case-by-case basis. Such a methodology is presented here.
Abstract: Dual phase steels (DPS)s have a microstructure
consisting of a hard second phase called Martensite in the soft Ferrite
matrix. In recent years, there has been interest in dual-phase steels,
because the application of these materials has made significant usage;
particularly in the automotive sector Composite microstructure of
(DPS)s exhibit interesting characteristic mechanical properties such
as continuous yielding, low yield stress to tensile strength
ratios(YS/UTS), and relatively high formability; which offer
advantages compared with conventional high strength low alloy
steels(HSLAS). The research dealt with the characterization of
damage in (DPS)s. In this study by review the mechanisms of failure
due to volume fraction of martensite second phase; a new method is
introduced to identifying the mechanisms of failure in the various
phases of these types of steels. In this method the acoustic emission
(AE) technique was used to detect damage progression. These failure
mechanisms consist of Ferrite-Martensite interface decohesion and/or
martensite phase fracture. For this aim, dual phase steels with
different volume fraction of martensite second phase has provided by
various heat treatment methods on a low carbon steel (0.1% C), and
then AE monitoring is used during tensile test of these DPSs. From
AE measurements and an energy ratio curve elaborated from the
value of AE energy (it was obtained as the ratio between the strain
energy to the acoustic energy), that allows detecting important
events, corresponding to the sudden drops. These AE signals events
associated with various failure mechanisms are classified for ferrite
and (DPS)s with various amount of Vm and different martensite
morphology. It is found that AE energy increase with increasing Vm.
This increasing of AE energy is because of more contribution of
martensite fracture in the failure of samples with higher Vm. Final
results show a good relationship between the AE signals and the
mechanisms of failure.
Abstract: The evaluation and measurement of human body
dimensions are achieved by physical anthropometry. This research
was conducted in view of the importance of anthropometric indices
of the face in forensic medicine, surgery, and medical imaging. The
main goal of this research is to optimization of facial feature point by
establishing a mathematical relationship among facial features and
used optimize feature points for age classification. Since selected
facial feature points are located to the area of mouth, nose, eyes and
eyebrow on facial images, all desire facial feature points are extracted
accurately. According this proposes method; sixteen Euclidean
distances are calculated from the eighteen selected facial feature
points vertically as well as horizontally. The mathematical
relationships among horizontal and vertical distances are established.
Moreover, it is also discovered that distances of the facial feature
follows a constant ratio due to age progression. The distances
between the specified features points increase with respect the age
progression of a human from his or her childhood but the ratio of the
distances does not change (d = 1 .618 ) . Finally, according to the
proposed mathematical relationship four independent feature
distances related to eight feature points are selected from sixteen
distances and eighteen feature point-s respectively. These four feature
distances are used for classification of age using Support Vector
Machine (SVM)-Sequential Minimal Optimization (SMO) algorithm
and shown around 96 % accuracy. Experiment result shows the
proposed system is effective and accurate for age classification.
Abstract: The major objective of this paper is to introduce a new method to select genes from DNA microarray data. As criterion to select genes we suggest to measure the local changes in the correlation graph of each gene and to select those genes whose local changes are largest. More precisely, we calculate the correlation networks from DNA microarray data of cervical cancer whereas each network represents a tissue of a certain tumor stage and each node in the network represents a gene. From these networks we extract one tree for each gene by a local decomposition of the correlation network. The interpretation of a tree is that it represents the n-nearest neighbor genes on the n-th level of a tree, measured by the Dijkstra distance, and, hence, gives the local embedding of a gene within the correlation network. For the obtained trees we measure the pairwise similarity between trees rooted by the same gene from normal to cancerous tissues. This evaluates the modification of the tree topology due to tumor progression. Finally, we rank the obtained similarity values from all tissue comparisons and select the top ranked genes. For these genes the local neighborhood in the correlation networks changes most between normal and cancerous tissues. As a result we find that the top ranked genes are candidates suspected to be involved in tumor growth. This indicates that our method captures essential information from the underlying DNA microarray data of cervical cancer.