Abstract: The mechanisms underlying the association between
obesity and asthma may be related to a decreased immunological
tolerance induced by a defective function of regulatory T cells
(Tregs). The aim of this study is to establish the potential link
between these diseases and CD4+, CD25+ FoxP3+ Tregs as well as T
helper cells (Ths) in children. This is a prospective case control
study. Obese (n:40), asthmatic (n:40), asthmatic obese (n:40) and
healthy children (n:40), who don't have any acute or chronic diseases,
were included in this study. Obese children were evaluated according
to WHO criteria. Asthmatic patients were chosen based on GINA
criteria. Parents were asked to fill up the questionnaire. Informed
consent forms were taken. Blood samples were marked with CD4+,
CD25+ and FoxP3+ in order to determine Tregs and Ths by flow
cytometric method. Statistical analyses were performed. p≤0.05 was
chosen as meaningful threshold. Tregs exhibiting anti-inflammatory
nature were significantly lower in obese (0,16%; p≤0,001), asthmatic
(0,25%; p≤0,01) and asthmatic obese (0,29%; p≤0,05) groups than
the control group (0,38%). Ths were counted higher in asthma group
than the control (p≤0,01) and obese (p≤0,001) groups. T cell
immunity plays important roles in obesity and asthma pathogeneses.
Decreased numbers of Tregs found in obese, asthmatic and asthmatic
obese children may help to elucidate some questions in
pathophysiology of these diseases. For HOMA-IR levels, any
significant difference was not noted between control and obese
groups, but statistically higher values were found for obese
asthmatics. The values obtained in all groups were found to be below
the critical cut off points. This finding has made the statistically
significant difference observed between Tregs of obese, asthmatic,
obese asthmatic and control groups much more valuable. These
findings will be useful in diagnosis and treatment of these disorders
and future studies are needed. The production and propagation of
Tregs may be promising in alternative asthma and obesity treatments.
Abstract: Increasing prevalence of childhood obesity has
increased the interest in early and late indicators of gaining weight.
Cell blood counts may be indicators of pro-inflammatory states. The
aim was to evaluate associations of hematological parameters,
including hematocrit (HTC), hemoglobin, blood cell counts and their
indices with the degree of obesity in pediatric population. A total of
249; -139 morbidly obese (MO), 82 healthy normal weight (NW) and
28 overweight (OW) children were included into the scope of the
study. WHO BMI-for age percentiles were used to form age- and sexmatched
groups. Informed consent forms and the Ethics Committee
approval were obtained. Anthropometric measurements were
performed. Hematological parameters were determined. Statistical
analyses were performed using SPSS. The degree for statistical
significance was p≤0.05. Significant differences (p=0.000) between
waist-to-hip ratios and head-to- neck ratios (hnrs) of MO and NW
children were detected. A significant difference between hnrs of OW
and MO children (p=0.000) was observed. Red cell distribution width
(RDW) was higher in OW children than NW group (p=0.030). Such
finding couldn’t be detected between MO and NW groups. Increased
RDW was prominent in OW children. The decrease in mean
corpuscular hemoglobin concentration (MCHC) values in MO
children was sharper than the values in OW children (p=0.006 vs
p=0.042) compared to those in NW group. Statistically higher HTC
levels were observed between MO-NW (p=0.014), but none between
OW-NW. Though the cause-effect relationship between obesity and
erythrocyte indices still needs further investigation, alterations in
RDW, HTC, MCHC during obesity may be of significance in the
early life.
Abstract: Background - The TrendCare Patient Dependency
System is currently used by a large number of maternity Services
across Australia, New Zealand and Singapore. In 2012, 2013 and
2014 validation studies were initiated in all three countries to validate
the acuity tools used for women in labour, and postnatal mothers and
babies. This paper will present the findings of the validation study.
Aim - The aim of this study was to; identify if the care hours
provided by the TrendCare acuity system was an accurate reflection
of the care required by women and babies; obtain evidence of
changes required to acuity indicators and/or category timings to
ensure the TrendCare acuity system remains reliable and valid across
a range of maternity care models in three countries.
Method - A non-experimental action research methodology was
used across maternity services in four District Health Boards in New
Zealand, a large tertiary and a large secondary maternity service in
Singapore and a large public maternity service in Australia.
Standardised data collection forms and timing devices were used to
collect midwife contact times, with women and babies included in the
study. Rejection processes excluded samples when care was not
completed/rationed, and contact timing forms were incomplete. The
variances between actual timed midwife/mother/baby contact and the
TrendCare acuity category times were identified and investigated.
Results - Thirty two (88.9%) of the 36 TrendCare acuity category
timings, fell within the variance tolerance levels when compared to
the actual timings recorded for midwifery care. Four (11.1%)
TrendCare categories provided less minutes of care than the actual
timings and exceeded the variance tolerance level. These were all
night shift category timings. Nine postnatal categories were not able
to be compared as the sample size for these categories was
statistically insignificant. 100% of labour ward TrendCare categories
matched actual timings for midwifery care, all falling within the
variance tolerance levels.
The actual time provided by core midwifery staff to assist lead
maternity carer (LMC) midwives in New Zealand labour wards
showed a significant deviation to previous studies. The findings of
the study demonstrated the need for additional time allocations in
TrendCare to accommodate an increased level of assistance given to
LMC midwives.
Conclusion - The results demonstrated the importance of regularly
validating the TrendCare category timings with actual timings of the
care hours provided. It was evident from the findings that variances
to models of care and length of stay in maternity units have increased
midwifery workloads on the night shift. The level of assistance
provided by the core labour ward staff to the LMC midwife has
increased substantially.
Outcomes - As a consequence of this study, changes were made to
the night duty TrendCare maternity categories, additional acuity
indicators were developed and times for assisting LMC midwives in
labour ward increased. The updated TrendCare version was delivered
to maternity services in 2014.
Abstract: Specific leaf area (SLA; cm2leaf g-1leaf) the ratio of leaf
area to leaf dry mass is a key ecophysiological parameter influencing
leaf physiology, photosynthesis, and whole plant carbon gain and
also can be used as a rapid and diagnostic tool. In this study, two
species of soluble inorganic selenium forms, selenite (Se^IV) and
selenate (Se^VI) at different concentrations were investigated on maize
plants that were growing in nutrient solutions during 2 weeks and at
the end of the experiment, amounts of SLA for first and second
leaves of maize were measured. In accordance with the results we
observed that our regarded Se concentrations in both forms of Se^IV
and Se^VI were not effective on maize plants’ SLA significantly
although high level of 3 mg.kg-1 Se^IV had negative affect on growth
of the samples that had been treated by it but about Se^VI samples we
did not observe this state and our different considered Se^VI
concentrations were not toxic for maize plants.
Abstract: Experimental study on slicing of sapphire with fixed
abrasive diamond wire saw was conducted in this paper. The process
parameters were optimized through orthogonal experiment of three
factors and four levels. The effects of wire speed, feed speed and
tension pressure on the surface roughness were analyzed. Surface
roughness in cutting direction and feed direction were both detected.
The results show that feed speed plays the most significant role on the
surface roughness of sliced sapphire followed by wire speed and
tension pressure. The optimized process parameters are as follows:
wire speed 1.9 m/s, feed speed 0.187 mm/min and tension pressure
0.18 MPa. In the end, the results were verified by analysis of variance.
Abstract: In this paper, a direct power control (DPC)
strategies have been investigated in order to control a high
power AC/DC converter with time variable load. This converter
is composed of a three level three phase neutral point clamped
(NPC) converter as rectifier and an H-bridge four quadrant
current control converter. In the high power application,
controller not only must adjust the desire outputs but also
decrease the level of distortions which are injected to the network
from the converter. Regarding to this reason and nonlinearity
of the power electronic converter, the conventional controllers
cannot achieve appropriate responses. In this research, the
precise mathematical analysis has been employed to design the
appropriate controller in order to control the time variable
load. A DPC controller has been proposed and simulated using
Matlab/ Simulink. In order to verify the simulation result, a real
time simulator- OPAL-RT- has been employed. In this paper,
the dynamic response and stability of the high power NPC
with variable load has been investigated and compared with
conventional types using a real time simulator. The results proved
that the DPC controller is more stable and has more precise
outputs in comparison with conventional controller.
Abstract: In the past researchers have questioned the
effectiveness of ethics training in higher education. Also, there are
observations that support the view that ethical behaviour (range of
actions)/ethical decision making models used in the past make use of
vignettes to explain ethical behaviour. The understanding remains in
the perspective that these vignettes play a limited role in determining
individual intentions and not actions. Some authors have also agreed
that there are possibilities of differences in one’s intentions and
actions. This paper makes an attempt to fill those gaps by evaluating
real actions rather than intentions. In a way this study suggests the
use of an experiential methodology to explore Berlo’s model of
communication as an action along with orchestration of various
principles. To this endeavor, an attempt was made to use
conversational analysis in the pursuance of evaluating ethical
decision making behaviour among students and middle level
managers. The process was repeated six times with the set of an
average of 15 participants. Similarities have been observed in the
behaviour of students and middle level managers that calls for
understanding that both the groups of individuals have no cognizance
of their actual actions. The deliberations derived out of conversation
were taken a step forward for meta-ethical evaluations to portray a
clear picture of ethical behaviour among participants. This study
provides insights for understanding demonstrated unconscious human
behaviour which may fortuitously be termed both ethical and
unethical.
Abstract: The aim of software maintenance is to maintain
the software system in accordance with advancement in software
and hardware technology. One of the early works on software
maintenance is to extract information at higher level of abstraction. In
this paper, we present the process of how to design an information
extraction tool for software maintenance. The tool can extract the
basic information from old programs such as about variables, based
classes, derived classes, objects of classes, and functions. The tool
have two main parts; the lexical analyzer module that can read the
input file character by character, and the searching module which
users can get the basic information from the existing programs. We
implemented this tool for a patterned sub-C++ language as an input
file.
Abstract: This study analyzes the innovative orientation of the
Croatian entrepreneurs. Innovative orientation is represented by the
perceived extent to which an entrepreneur’s product or service or
technology is new, and no other businesses offer the same product.
The sample is extracted from the GEM Croatia Adult Population
Survey dataset for the years 2003-2013. We apply descriptive
statistics, t-test, Chi-square test and logistic regression. Findings
indicate that innovative orientations vary with personal, firm, meso
and macro level variables, and between different stages in
entrepreneurship process. Significant predictors are occupation of the
entrepreneurs, size of the firm and export aspiration for both early
stage and established entrepreneurs. In addition, fear of failure,
expecting to start a new business and seeing an entrepreneurial career
as a desirable choice are predictors of innovative orientation among
early stage entrepreneurs.
Abstract: International and domestic environmental law has
evolved quite rapidly in the last few decades. At the international
level the Stockholm and Rio Declarations paved the way for a broad
based consensus of the international community on environmental
issues and principles. At the Domestic level also many states have
incorporated environmental protection in their constitutions and even
more states are doing the same at least in their domestic legislations.
In this process of evolution environmental law has unleashed a
number of novel principles such as; the participatory principle, the
polluter pays principle, the precautionary principle, the intergenerational
and intra-generational principles, the prevention
principle, the sustainable development principle and so on.
Abstract: Applications of the Hausdorff space and its mappings
into tangent spaces are outlined, including their fractal dimensions
and self-similarities. The paper details this theory set up and further
describes virtualizations and atomization of manufacturing processes.
It demonstrates novel concurrency principles that will guide
manufacturing processes and resources configurations. Moreover,
varying levels of details may be produced by up folding and breaking
down of newly introduced generic models. This choice of layered
generic models for units and systems aspects along specific aspects
allows research work in parallel to other disciplines with the same
focus on all levels of detail. More credit and easier access are granted
to outside disciplines for enriching manufacturing grounds. Specific
mappings and the layers give hints for chances for interdisciplinary
outcomes and may highlight more details for interoperability
standards, as already worked on the international level. The new rules
are described, which require additional properties concerning all
involved entities for defining distributed decision cycles, again on the
base of self-similarity. All properties are further detailed and assigned
to a maturity scale, eventually displaying the smartness maturity of a
total shopfloor or a factory. The paper contributes to the intensive
ongoing discussion in the field of intelligent distributed
manufacturing and promotes solid concepts for implementations of
Cyber Physical Systems and the Internet of Things into
manufacturing industry, like industry 4.0, as discussed in German-speaking
countries.
Abstract: This paper presents system level CMOS solid-state
nanopore techniques enhancement for speedup next generation
molecular recording and high throughput channels. This discussion
also considers optimum number of base-pair (bp) measurements
through channel as an important role to enhance potential read
accuracy. Effective power consumption estimation offered suitable
range of multi-channel configuration. Nanopore bp extraction model
in statistical method could contribute higher read accuracy with
longer read-length (200 < read-length). Nanopore ionic current
switching with Time Multiplexing (TM) based multichannel readout
system contributed hardware savings.
Abstract: An innovative concept called “Flexy-Energy” is developing at 2iE. This concept aims to produce electricity at lower cost by smartly mix different available energy sources in accordance to the load profile of the region. With a higher solar irradiation and due to the fact that Diesel generator are massively used in sub-Saharan rural areas, PV/Diesel hybrid systems could be a good application of this concept and a good solution to electrify this region, provided they are reliable, cost effective and economically attractive to investors. Presentation of the developed approach is the aims of this paper. The PV/Diesel hybrid system designed consists to produce electricity and/or heat from a coupling between Diesel Diesel generators and PV panels without batteries storage, while ensuring the substitution of gasoil by bio-fuels available in the area where the system will be installed. The optimal design of this system is based on his technical performances; the Life Cycle Cost (LCC) and Levelized Cost of Energy are developed and use as economic criteria. The Net Present Value (NPV), the internal rate of return (IRR) and the discounted payback (DPB) are also evaluated according to dual electricity pricing (in sunny and unsunny hours). The PV/Diesel hybrid system obtained is compared to the standalone Diesel Diesel generators. The approach carried out in this paper has been applied to Siby village in Mali (Latitude 12 ° 23'N 8 ° 20'W) with 295 kWh as daily demand.This approach provides optimal physical characteristics (size of the components, number of component) and dynamical characteristics in real time (number of Diesel generator on, their load rate, fuel specific consumptions, and PV penetration rate) of the system. The system obtained is slightly cost effective; but could be improved with optimized tariffing strategies.
Abstract: This paper reports the worldwide status of building
information modeling (BIM) adoption from the perspectives of the
engagement level, the Hype Cycle model, the technology diffusion
model, and BIM services. An online survey was distributed, and 156
experts from six continents responded. Overall, North America was
the most advanced continent, followed by Oceania and Europe.
Countries in Asia perceived their phase mainly as slope of
enlightenment (mature) in the Hype Cycle model. In the technology
diffusion model, the main BIM-users worldwide were “early majority”
(third phase), but those in the Middle East/Africa and South America
were “early adopters” (second phase). In addition, the more advanced
the country, the more number of BIM services employed in general. In
summary, North America, Europe, Oceania, and Asia were advancing
rapidly toward the mature stage of BIM, whereas the Middle
East/Africa and South America were still in the early phase. The
simple indexes used in this study may be used to track the worldwide
status of BIM adoption in long-term surveys.
Abstract: Soil quality monitoring is a science-based soil
management tool that assesses soil ecosystem health.
A soil monitoring program in Auckland, New Zealand’s largest
city extends from 1995 to the present. The objective of this study was
to firstly determine changes in soil parameters (basic soil properties
and heavy metals) that were assessed from rural land in 1995-2000
and repeated in 2008-2012. The second objective was to determine
differences in soil parameters across various land uses including
native bush, rural (horticulture, pasture and plantation forestry) and
urban land uses using soil data collected in more recent years (2009-
2013).
Across rural land, mean concentrations of Olsen P had
significantly increased in the second sampling period and was
identified as the indicator of most concern, followed by soil
macroporosity, particularly for horticultural and pastoral land. Mean
concentrations of Cd were also greatest for pastoral and horticultural
land and a positive correlation existed between these two parameters,
which highlights the importance of analysing basic soil parameters in
conjunction with heavy metals. In contrast, mean concentrations of
As, Cr, Pb, Ni and Zn were greatest for urban sites. Native bush sites
had the lowest concentrations of heavy metals and were used to
calculate a ‘pollution index’ (PI). The mean PI was classified as high
(PI > 3) for Cd and Ni and moderate for Pb, Zn, Cr, Cu, As and Hg,
indicating high levels of heavy metal pollution across both rural and
urban soils. From a land use perspective, the mean ‘integrated
pollution index’ was highest for urban sites at 2.9 followed by
pasture, horticulture and plantation forests at 2.7, 2.6 and 0.9,
respectively.
It is recommended that soil sampling continues over time because
a longer spanning record will allow further identification of where
soil problems exist and where resources need to be targeted in the
future. Findings from this study will also inform policy and science
direction in regional councils.
Abstract: This paper is a report on the findings of a study
conducted at the Institute of Public Administration (IPA) in Saudi
Arabia. The paper applied both qualitative and quantitative
approaches to assess the levels of basic computer applications’ skills
among students enrolled in the preparatory programs of the
institution. Qualitative data have been collected from semi-structured
interviews with the instructors who have previously been assigned to
teach Introduction to information technology courses. Quantitative
data were collected by executing a self-report questionnaire and a
written statistical test. Three hundred eighty enrolled students
responded to the questionnaire and one hundred forty two
accomplished the statistical test. The results indicate the lack of
necessary skills to deal with computer applications among most of
the students who are enrolled in the IPA’s preparatory programs.
Abstract: If teamwork is the key to organizational learning,
productivity and growth, then, why do some teams succeed in
achieving these, while others falter at different stages? Building
teams in higher education institutions has been a challenge and an
open-ended constructivist approach was considered on an
experimental basis for this study to address this challenge. For this
research, teams of students from the MBA program were chosen to
study the effect of teamwork in learning, the motivation levels among
student team members, and the effect of collaboration in achieving
team goals. The teams were built on shared vision and goals,
cohesion was ensured, positive induction in the form of faculty
mentoring was provided for each participating team and the results
have been presented with conclusions and suggestions.
Abstract: There is a trend in development discourse to
understand and explain the level of corruption in Nigeria, its anticorruption
crusade and why it is failing, as well as its level of
compliance with International standards of United Nations
Convention against Corruption (UNCAC) & African Union
Convention on Converting and Preventing Corruption) to which
Nigeria is a signatory. This paper discusses the legal and
Constitutional provisions relating to corrupt practices and safeguards
in Nigeria, as well as the obstacles to the implementation of these
Conventions.
The paper highlights the challenges posed to the Anti-Corruption
crusade by analysing the loopholes that exist both in administrative
structure and in scope of the relevant laws. The paper argues that
Nigerian Constitution did not make adequate provisions for the
implementation of the conventions, hence a proposal which will
ensure adequate provision for implementing the conventions to better
the lives of Nigerians. The paper concludes that there is the need to
build institutional parameters, adequate constitutional and structural
safeguards, as well as to synergise strategies, collaborations and
alliances to facilitate the timely domestication and implementation of
the conventions.
Abstract: In this paper, we discuss the performance of applying
hybrid spiral dynamic bacterial chemotaxis (HSDBC) optimisation
algorithm on an intelligent controller for a differential drive robot. A
unicycle class of differential drive robot is utilised to serve as a basis
application to evaluate the performance of the HSDBC algorithm. A
hybrid fuzzy logic controller is developed and implemented for the
unicycle robot to follow a predefined trajectory. Trajectories of
various frictional profiles and levels were simulated to evaluate the
performance of the robot at different operating conditions. Controller
gains and scaling factors were optimised using HSDBC and the
performance is evaluated in comparison to previously adopted
optimisation algorithms. The HSDBC has proven its feasibility in
achieving a faster convergence toward the optimal gains and resulted
in a superior performance.
Abstract: The objectives of the study were to determine the
marketing mix factors that influencing tourist’s destination decision
making for cultural tourism in the Chonburi province. Both
quantitative and qualitative data were applied in this study. The
samples of 400 cases for quantitative analysis were tourists (both
Thai and foreign) who were interested in cultural tourism in the
Chonburi province, and traveled to cultural sites in Chonburi and 14
representatives from provincial tourism committee of Chonburi and
local tourism experts. Statistics utilized in this research included
frequency, percentage, mean, standard deviation, and multiple
regression analysis. The study found that Thai and foreign tourists
are influenced by different important marketing mix factors. The
important factors for Thai respondents were physical evidence, price,
people, and place at high importance level. For foreign respondents,
physical evidence, price, people, and process were high importance
level, whereas, product, place and promotion were moderate
importance level.