Abstract: Transcription factor p53 has a powerful tumor
suppressing function that is associated with many cancers. However,
p53 of the molecular weight was higher make the limitation across to
skin or cell membrane. Thymidine dinucleotide (pTT), an
oligonucleotide, can activate the p53 transcription factor. pTT is a
hydrophilic and negative charge oligonucleotide, which delivery in to
cell membrane need an appropriate carrier. The aim of this study was
to improve the bioavailability of the nucleotide fragment, thymidine
dinucleotide (pTT), using elasic liposome carriers to deliver the drug
into the skin. The study demonstrate that dioleoylphosphocholine
(DOPC) incorporated with sodium cholate at molar ratio 1:1 can
archived the particle size about 220 nm. This elastic liposome could
penetration through skin from stratum corneum to whole epidermis by
confocal laser scanning microscopy (CLSM). Moreover, we observed
the the slight increase in generation of p53 by western blot.
Abstract: Groundwater is one of the most important water
resources in Fars province. Based on this study, 95 percent of the
total annual water consumption in Fars is used for agriculture,
whereas the percentages for domestic and industrial uses are 4 and 1
percent, respectively. Population growth, urban and industrial
growth, and agricultural development in Fars have created a
condition of water stress. In this province, farmers and other users are
pumping groundwater faster than its natural replenishment rate,
causing a continuous drop in groundwater tables and depletion of this
resource. In this research variation of groundwater level, their effects
and ways to help control groundwater levels in aquifer of the Kavar-
Maharloo plains in Fars plain were evaluated .Excessive
exploitation of groundwater in this aquifer caused the groundwater
levels fall too fast or to unacceptable levels. The average drawdown
of the groundwater level in this plain were 17 meters during
1995 to 2006. The purpose of this study is to evaluate water level
changes in the Kavar-Maharloo Aquifer in the Fars province in order
to determine the areas of greatest depletion, the cause of depletion,
and predict the remaining life of the aquifer.
Abstract: This paper reports the three-phase (gas + liquid +
hydrate) equilibrium pressure versus temperature data for a (O3 + O2 +
CO2 + H2O) system for developing the hydrate-based technology to
preserve ozone, a chemically unstable substance, for various
industrial, medical and consumer uses. These data cover the
temperature range from 272 K to 277 K, corresponding to pressures
from 1.6 MPa to 3.1 MPa, for each of the three different (O3 +
O2)-to-CO2 or O2-to-CO2 molar ratios in the gas phase, which are
approximately 4 : 6, 5 : 5, respectively. The mole fraction of ozone in
the gas phase was ~0.03 , which are the densest ozone fraction to
artificially form O3 containing hydrate ever reported in the literature.
Based on these data, the formation of hydrate containing
high-concentration ozone, as high as 1 mass %, will be expected.
Abstract: A parallel block method based on Backward
Differentiation Formulas (BDF) is developed for the parallel solution
of stiff Ordinary Differential Equations (ODEs). Most common
methods for solving stiff systems of ODEs are based on implicit
formulae and solved using Newton iteration which requires repeated
solution of systems of linear equations with coefficient matrix, I -
hβJ . Here, J is the Jacobian matrix of the problem. In this paper,
the matrix operations is paralleled in order to reduce the cost of the
iterations. Numerical results are given to compare the speedup and
efficiency of parallel algorithm and that of sequential algorithm.
Abstract: This paper presents preliminary results on modeling
and control of a quadrotor UAV. With aerodynamic concepts, a
mathematical model is firstly proposed to describe the dynamics
of the quadrotor UAV. Parameters of this model are identified by
experiments with Matlab Identify Toolbox. A group of PID controllers
are then designed based on the developed model. To verify
the developed model and controllers, simulations and experiments for
altitude control, position control and trajectory tracking are carried
out. The results show that the quadrotor UAV well follows the
referenced commands, which clearly demonstrates the effectiveness
of the proposed approach.
Abstract: With rapid technology scaling, the proportion of the
static power consumption catches up with dynamic power
consumption gradually. To decrease leakage consumption is
becoming more and more important in low-power design. This paper
presents a power-gating scheme for P-DTGAL (p-type dual
transmission gate adiabatic logic) circuits to reduce leakage power
dissipations under deep submicron process. The energy dissipations of
P-DTGAL circuits with power-gating scheme are investigated in
different processes, frequencies and active ratios. BSIM4 model is
adopted to reflect the characteristics of the leakage currents. HSPICE
simulations show that the leakage loss is greatly reduced by using the
P-DTGAL with power-gating techniques.
Abstract: Both the minimum energy consumption and
smoothness, which is quantified as a function of jerk, are generally
needed in many dynamic systems such as the automobile and the
pick-and-place robot manipulator that handles fragile equipments.
Nevertheless, many researchers come up with either solely
concerning on the minimum energy consumption or minimum jerk
trajectory. This research paper proposes a simple yet very interesting
when combining the minimum energy and jerk of indirect jerks
approaches in designing the time-dependent system yielding an
alternative optimal solution. Extremal solutions for the cost functions
of the minimum energy, the minimum jerk and combining them
together are found using the dynamic optimization methods together
with the numerical approximation. This is to allow us to simulate
and compare visually and statistically the time history of state inputs
employed by combining minimum energy and jerk designs. The
numerical solution of minimum direct jerk and energy problem are
exactly the same solution; however, the solutions from problem of
minimum energy yield the similar solution especially in term of
tendency.
Abstract: Recently the use of data mining to scientific bibliographic data bases has been implemented to analyze the pathways of the knowledge or the core scientific relevances of a laureated novel or a country. This specific case of data mining has been named citation mining, and it is the integration of citation bibliometrics and text mining. In this paper we present an improved WEB implementation of statistical physics algorithms to perform the text mining component of citation mining. In particular we use an entropic like distance between the compression of text as an indicator of the similarity between them. Finally, we have included the recently proposed index h to characterize the scientific production. We have used this web implementation to identify users, applications and impact of the Mexican scientific institutions located in the State of Morelos.
Abstract: The Kumamoto area, Kyushu, Japan has 1,041km2 in
area and about 1milion in population. This area is a greatest area in Japan which depends on groundwater for all of drinking water. Quantity of this local groundwater use is about 200MCM during the
year. It is understood that the main recharging area of groundwater exist in the rice field zone which have high infiltrate height ahead of
100mm/ day of the irrigated water located in the middle area of the Shira-River Basin. However, by decrease of the paddy-rice planting
area by urbanization and an acreage reduction policy, the groundwater income and expenditure turned worse. Then Kumamoto city and four
companies expended financial support to increase recharging water to
underground by ponded water in the field from 2004.
In this paper, the author reported the situation of recovery of groundwater by recharge and estimates the efficiency of recharge by
statistical method.
Abstract: In North America, Most power distribution systems
employ a four-wire multi-grounded neutral (MGN) design. This paper has explained the inherent characteristics of multi-grounded three-phase four-wire distribution systems under unbalanced
situations. As a result, the mechanism of voltage swell and voltage sag in MGN feeders becomes difficult to understand. The simulation
tool that has been used in this paper is MATLAB under Windows software. In this paper the equivalent model of a full-scale multigrounded
distribution system implemented by MATLAB is
introduced. The results are expected to help utility engineers to understand the impact of MGN on distribution system operations.
Abstract: In mobile environments, unspecified numbers of transactions
arrive in continuous streams. To prove correctness of their
concurrent execution a method of modelling an infinite number of
transactions is needed. Standard database techniques model fixed
finite schedules of transactions. Lately, techniques based on temporal
logic have been proposed as suitable for modelling infinite schedules.
The drawback of these techniques is that proving the basic
serializability correctness condition is impractical, as encoding (the
absence of) conflict cyclicity within large sets of transactions results
in prohibitively large temporal logic formulae. In this paper, we show
that, under certain common assumptions on the graph structure of
data items accessed by the transactions, conflict cyclicity need only
be checked within all possible pairs of transactions. This results in
formulae of considerably reduced size in any temporal-logic-based
approach to proving serializability, and scales to arbitrary numbers
of transactions.
Abstract: This paper describes the speed sensorless vector control method of the parallel connected induction motor drive fed by a single inverter. Speed and rotor fluxes of the induction motor are estimated by natural observer with load torque adaptation and adaptive rotor flux observer. The performance parameters speed and rotor fluxes are estimated from the measured terminal voltages and currents. Fourth order induction motor model is used and speed is considered as a parameter. The performance of the natural observer is similar to the conventional observer. The speed of an induction motor is estimated by MATLAB simulation under different speed and load conditions. Estimated values along with other measured states are used for closed loop control. The simulation results show that the natural observer is also effective for parallel connected induction motor drive.
Abstract: The application of a simple microcontroller to deal
with a three variable input and a single output fuzzy logic controller,
with Proportional – Integral – Derivative (PID) response control
built-in has been tested for an automatic voltage regulator. The
fuzzifiers are based on fixed range of the variables of output voltage.
The control output is used to control the wiper motor of the auto
transformer to adjust the voltage, using fuzzy logic principles, so that
the voltage is stabilized. In this report, the author will demonstrate
how fuzzy logic might provide elegant and efficient solutions in the
design of multivariable control based on experimental results rather
than on mathematical models.
Abstract: This paper is intended to assist anyone with some general technical experience, but perhaps limited specific knowledge of heat transfer equipment. A characteristic of heat exchanger design is the procedure of specifying a design, heat transfer area and pressure drops and checking whether the assumed design satisfies all requirements or not. The purpose of this paper is how to design the oil cooler (heat exchanger) especially for shell-and-tube heat exchanger which is the majority type of liquid-to-liquid heat exchanger. General design considerations and design procedure are also illustrated in this paper and a flow diagram is provided as an aid of design procedure. In design calculation, the MatLAB and AutoCAD software are used. Fundamental heat transfer concepts and complex relationships involved in such exchanger are also presented in this paper. The primary aim of this design is to obtain a high heat transfer rate without exceeding the allowable pressure drop. This computer program is highly useful to design the shell-and-tube type heat exchanger and to modify existing deign.
Abstract: Recently, various services such as television and the
Internet have come to be received through various terminals.
However, we could gain greater convenience by receiving these
services through cellular phone terminals when we go out and then
continuing to receive the same services through a large screen digital
television after we have come home. However, it is necessary to go
through the same authentication processing again when using TVs
after we have come home. In this study, we have developed an
authentication method that enables users to switch terminals in
environments in which the user receives service from a server through
a terminal. Specifically, the method simplifies the authentication of
the server side when switching from one terminal to another terminal
by using previously authenticated information.
Abstract: Flow movement in unsaturated soil can be expressed
by a partial differential equation, named Richards equation. The
objective of this study is the finding of an appropriate implicit
numerical solution for head based Richards equation. Some of the
well known finite difference schemes (fully implicit, Crank Nicolson
and Runge-Kutta) have been utilized in this study. In addition, the
effects of different approximations of moisture capacity function,
convergence criteria and time stepping methods were evaluated. Two
different infiltration problems were solved to investigate the
performance of different schemes. These problems include of vertical
water flow in a wet and very dry soils. The numerical solutions of
two problems were compared using four evaluation criteria and the
results of comparisons showed that fully implicit scheme is better
than the other schemes. In addition, utilizing of standard chord slope
method for approximation of moisture capacity function, automatic
time stepping method and difference between two successive
iterations as convergence criterion in the fully implicit scheme can
lead to better and more reliable results for simulation of fluid
movement in different unsaturated soils.
Abstract: The condition of lightning surge causes the traveling waves and the temporary increase in voltage in the transmission line system. Lightning is the most harmful for destroying the transmission line and setting devices so it is necessary to study and analyze the temporary increase in voltage for designing and setting the surge arrester. This analysis describes the figure of the lightning wave in transmission line with 115 kV voltage level in Thailand by using ATP/EMTP program to create the model of the transmission line and lightning surge. Because of the limit of this program, it must be calculated for the geometry of the transmission line and surge parameter and calculation in the manual book for the closest value of the parameter. On the other hand, for the effects on surge protector when the lightning comes, the surge arrester model must be right and standardized as metropolitan electrical authority's standard. The candidate compared the real information to the result from calculation, also. The results of the analysis show that the temporary increase in voltage value will be rise to 326.59 kV at the line which is done by lightning when the surge arrester is not set in the system. On the other hand, the temporary increase in voltage value will be 182.83 kV at the line which is done by lightning when the surge arrester is set in the system and the period of the traveling wave is reduced, also. The distance for setting the surge arrester must be as near to the transformer as possible. Moreover, it is necessary to know the right distance for setting the surge arrester and the size of the surge arrester for preventing the temporary increase in voltage, effectively.
Abstract: Amongst the consistently fluctuating conditions
prevailing today, changeability represents a strategic key factor for a
manufacturing company to achieve success on the international
markets. In order to cope with turbulences and the increasing level of
incalculability, not only the flexible design of production systems but
in particular the employee as enabler of change provide the focus
here. It is important to enable employees from manufacturing
companies to participate actively in change events and in change
decisions. To this end, the learning factory has been created, which is
intended to serve the development of change-promoting competences
and the sensitization of employees for the necessity of changes.
Abstract: A computer model of Quantum Theory (QT) has been
developed by the author. Major goal of the computer model was
support and demonstration of an as large as possible scope of QT.
This includes simulations for the major QT (Gedanken-) experiments
such as, for example, the famous double-slit experiment.
Besides the anticipated difficulties with (1) transforming exacting
mathematics into a computer program, two further types of problems
showed up, namely (2) areas where QT provides a complete mathematical
formalism, but when it comes to concrete applications the
equations are not solvable at all, or only with extremely high effort;
(3) QT rules which are formulated in natural language and which do
not seem to be translatable to precise mathematical expressions, nor
to a computer program.
The paper lists problems in all three categories and describes also
the possible solutions or circumventions developed for the computer
model.
Abstract: We constructed a method of phase unwrapping for a typical wave-front by utilizing the maximizer of the posterior marginal (MPM) estimate corresponding to equilibrium statistical mechanics of the three-state Ising model on a square lattice on the basis of an analogy between statistical mechanics and Bayesian inference. We investigated the static properties of an MPM estimate from a phase diagram using Monte Carlo simulation for a typical wave-front with synthetic aperture radar (SAR) interferometry. The simulations clarified that the surface-consistency conditions were useful for extending the phase where the MPM estimate was successful in phase unwrapping with a high degree of accuracy and that introducing prior information into the MPM estimate also made it possible to extend the phase under the constraint of the surface-consistency conditions with a high degree of accuracy. We also found that the MPM estimate could be used to reconstruct the original wave-fronts more smoothly, if we appropriately tuned hyper-parameters corresponding to temperature to utilize fluctuations around the MAP solution. Also, from the viewpoint of statistical mechanics of the Q-Ising model, we found that the MPM estimate was regarded as a method for searching the ground state by utilizing thermal fluctuations under the constraint of the surface-consistency condition.