Abstract: One of the functions of the commercial heavy vehicle
is to safely and efficiently transport goods and people. Due to its size
and carrying capacity, it is important to study the vehicle dynamic
stability during cornering. Study has shown that there are a number of
overloaded heavy vehicles or permissible Gross Vehicle Weight
(GVW) violations recorded at selected areas in Malaysia assigned by
its type and category. Thus, the objective of this study is to
investigate the correlation and effect of the GVW on heavy vehicle
stability during cornering event using simulation. Various selected
heavy vehicle types and category are simulated using IPG/Truck
Maker® with different GVW and road condition (coefficient of
friction of road surface), while the speed, driver characteristic, center
of gravity of load and road geometry are constant. Based on the
analysis, the relationship between GVW and lateral acceleration were
established. As expected, on the same value of coefficient of friction,
the maximum lateral acceleration would be increased as the GVW
increases.
Abstract: The sea waves carry thousands of GWs of power
globally. Although there are a number of different approaches to
harness offshore energy, they are likely to be expensive, practically
challenging, and vulnerable to storms. Therefore, this paper considers
using the near shore waves for generating mechanical and electrical
power. It introduces two new approaches, the wave manipulation and
using a variable duct turbine, for intercepting very wide wave fronts
and coping with the fluctuations of the wave height and the sea level,
respectively. The first approach effectively allows capturing much
more energy yet with a much narrower turbine rotor. The second
approach allows using a rotor with a smaller radius but captures
energy of higher wave fronts at higher sea levels yet preventing it
from totally submerging. To illustrate the effectiveness of the first
approach, the paper contains a description and the simulation results
of a scale model of a wave manipulator. Then, it includes the results
of testing a physical model of the manipulator and a single duct, axial
flow turbine in a wave flume in the laboratory. The paper also
includes comparisons of theoretical predictions, simulation results,
and wave flume tests with respect to the incident energy, loss in wave
manipulation, minimal loss, brake torque, and the angular velocity.
Abstract: In this paper, we proposed a novel SCR (Silicon Controlled
Rectifier) - based ESD (Electrostatic Discharge) protection device for I/O
and power clamp. The proposed device has a higher holding voltage
characteristic than conventional SCR. These characteristics enable to have
latch-up immunity under normal operating conditions as well as superior full
chip ESD protection. The proposed device was analyzed to figure out
electrical characteristics and tolerance robustness in term of individual
design parameters (D1, D2, D3). They are investigated by using the
Synopsys TCAD simulator. As a result of simulation, holding voltage
increased with different design parameters. The holding voltage of the
proposed device changes from 3.3V to 7.9V. Also, N-Stack structure ESD
device with the high holding voltage is proposed. In the simulation results,
2-stack has holding voltage of 6.8V and 3-stack has holding voltage of
10.5V. The simulation results show that holding voltage of stacking
structure can be larger than the operation voltage of high-voltage
application.
Abstract: In this study free vibration analysis of aluminum
honeycomb sandwich structures were carried out experimentally and
numerically. The natural frequencies and mode shapes of sandwich
structures fabricated with different configurations for clamped-free
boundary condition were determined. The effects of lower and upper
face sheet thickness, the core material thickness, cell diameter, cell
angle and foil thickness on the vibration characteristics were
examined. The numerical studies were performed with ANSYS
package. While the sandwich structures were modeled in ANSYS the
continuum model was used. Later, the numerical results were
compared with the experimental findings.
Abstract: Hemoglobin (HB) indicates anemia level and by
extension may reflect the nutritional level and perhaps the immunity
of an individual. Some antiretroviral drugs like Zidovudine are
known to cause anemia in people living with HIV/AIDS (PLWHA).
A cross sectional study using demographic data and blood specimen
from 218 female commercial sex workers attending antiretroviral
therapy (ART) clinics was conducted between December, 2009 and
July, 2011 to assess the effect of zidovudine on hematologic, and
RNA viral load of female sex workers receiving antiretroviral
treatment in north western Nigeria. Anemia is a common and serious
complication of both HIV infection and its treatment. In the setting of
HIV infection, anemia has been associated with decreased quality of
life, functional status, and survival. Antiretroviral therapy,
particularly the highly active antiretroviral therapy (HAART), has
been associated with a decrease in the incidence and severity of
anemia in HIV-infected patients who have received a HAART
regimen for at least 1 year. In this study, result has shown that of the
218 patients, 26 with hemoglobin count between 5.1 – 10g/dl were
observed to have the highest viral load count of 300,000 –
350,000copies/ml. It was also observed that most patients (190) with
HB of 10.1 – 15.0g/dl had viral load count of 200,000 – 250,000
copies /ml. An inverse relationship therefore exists i.e. the lower the
hemoglobin level, the higher the viral load count even though the test
statistics did not show any significance between the two (P = 0.206).
This shows that multivariate logistic regression analysis
demonstrated that anemia was associated with a CD4 + cell count
below 50/μL, female sex workers with a viral load above 100,000
copies/mL, who use zidovudine.
Severe anemia was less prevalent in this study population than in
historical comparators; however, mild to moderate anemia rates
remain high. The study therefore recommends that hematological and
virologic parameters be monitored closely in patients receiving first
line ART regimen.
Abstract: The modeling lung respiratory system that has complex anatomy and biophysics presents several challenges including tissue-driven flow patterns and wall motion. Also, the pulmonary lung system because of that they stretch and recoil with each breath, has not static walls and structures. The direct relationship between air flow and tissue motion in the lung structures naturally prefers an FSI simulation technique. Therefore, in order to toward the realistic simulation of pulmonary breathing mechanics the development of a coupled FSI computational model is an important step. A simple but physiologically relevant three-dimensional deep long geometry is designed and fluid-structure interaction (FSI) coupling technique is utilized for simulating the deformation of the lung parenchyma tissue that produces airflow fields. The real understanding of respiratory tissue system as a complex phenomenon have been investigated with respect to respiratory patterns, fluid dynamics and tissue viscoelasticity and tidal breathing period.
Abstract: The main objective of this study was to assess the
annual concentration and seasonal variation of benzo(a)pyrene (BaP)
associated with PM10 in an urban site of Győr and in a rural site of
Sarród in the sampling period of 2008–2012. A total of 280 PM10
aerosol samples were collected in each sampling site and analyzed for
BaP by gas chromatography method. The BaP concentrations ranged
from undetected to 8 ng/m3 with the mean value of 1.01 ng/m3 in the
sampling site of Győr, and from undetected to 4.07 ng/m3 with the
mean value of 0.52 ng/m3 in the sampling site of Sarród, respectively.
Relatively higher concentrations of BaP were detected in samples
collected in both sampling sites in the heating seasons compared with
non-heating periods. The annual mean BaP concentrations were
comparable with the published data of different other Hungarian
sites.
Abstract: Academicians at the Arab Open University have
always voiced their concern about the efficacy of the blended
learning process. Based on 75% independent study and 25% face-toface
tutorial, it poses the challenge of the predisposition to
adjustment. Being used to the psychology of traditional educational
systems, AOU students cannot be easily weaned from being spoonfed.
Hence they lack the motivation to plunge into self-study. For
better involvement of AOU students into the learning practices, it is
imperative to diagnose the factors that impede or increase their
motivation. This is conducted through an empirical study grounded
upon observations and tested hypothesis and aimed at monitoring and
optimizing the students’ learning outcome. Recommendations of the
research will follow the findings.
Abstract: The security of cloud services is the concern of cloud
service providers. In this paper, we will mention different
classifications of cloud attacks referred by specialized organizations.
Each agency has its classification of well-defined properties. The
purpose is to present a high-level classification of current research in
cloud computing security. This classification is organized around
attack strategies and corresponding defenses.
Abstract: In order to determine the impact of thermo priming on germination of soybean seeds, an experiment was conducted as a completely randomized design with three replications. The factors of studied included different time thermo priming (control, 5 and 10 minutes) through the placing seeds were exposed to oven. The results showed that the effect of thermo priming was significant on germination percentage, seedling dry weight and seedling vigour in P ≤ 0.05. Mean comparison showed that the highest germination percentage (77%), seedling dry weight (1.39 g) and seedling vigour (107.03) were achieved by 10 minutes thermo priming.
Abstract: There is not much effective guideline on development of design parameters selection on spring back for advanced high strength steel sheet metal in U-channel process during cold forming process. This paper presents the development of predictive model for spring back in U-channel process on advanced high strength steel sheet employing Response Surface Methodology (RSM). The experimental was performed on dual phase steel sheet, DP590 in Uchannel forming process while design of experiment (DoE) approach was used to investigates the effects of four factors namely blank holder force (BHF), clearance (C) and punch travel (Tp) and rolling direction (R) were used as input parameters using two level values by applying Full Factorial design (24 ). From a statistical analysis of variant (ANOVA), result showed that blank holder force (BHF), clearance (C) and punch travel (Tp) displayed significant effect on spring back of flange angle (β2 ) and wall opening angle (β1 ), while rolling direction (R) factor is insignificant. The significant parameters are optimized in order to reduce the spring back behavior using Central Composite Design (CCD) in RSM and the optimum parameters were determined. A regression model for spring back was developed. The effect of individual parameters and their response was also evaluated. The results obtained from optimum model are in agreement with the experimental values.
Abstract: This article briefly reviews the role of Indian
Pharmacopoeia Commission (IPC) for publications of Indian
Pharmacopoeia (IP) and National formulary of India (NFI) to some of
these anticipated changes, informs constituents about how they can
remain updated about progress and upcoming modifications to
official texts, and invites participation in the standards-setting
process, which are helpful to the practitioners, researchers, educators
and policy makers in the field of health care profession.
Abstract: More than 3000 plants of notable phyto-therapeutic
value grow in South Africa; these include Cissampelos capensis,
commonly known in Afrikaans as dawidjie or dawidjiewortel. C.
capensis is the most significant and popular medicinal plant used by
the Khoisan as well as other rural groups in the Western region of
South Africa. Its rhizomes are traditionally used to treat male fertility
problems. Yet, no studies have investigated the effects of this plant or
its extracts on human spermatozoa. Therefore, this study aimed at
investigating the effects of C. capensis rhizome extract (CRE)
fractions on ejaculated human spermatozoa in vitro. Spermatozoa
from a total of 77 semen samples were washed with human tubular
fluid medium supplemented with bovine serum albumin (HTF-BSA)
and incubated for 2 hours with 20 μg/ml progesterone (P4) followed
by incubation with different concentrations (0, 0.05, 0.5, 5, 50, 200
μg/ml) of fractionated CRE (F1=0% MeOH, F2=30% MeOH,
F3=60% MeOH and F4=100% MeOH) for 1.5 hours at 37°C. A
sample without addition of CRE fractions served as control. Samples
were analyzed for sperm motility, reactive oxygen species (ROS),
DNA-fragmentation, acrosome reaction and capacitation. Results
showed that F1 resulted in significantly higher values for ROS,
capacitation and hyper-activation compared to F2, F3, and F4 with
P4-stimulated samples generally having higher values. No significant
effect was found for the other parameters. In conclusion, alkaloids
present in F1 of CRE appear to have triggered sperm intrinsic ROS
production leading to sperm capacitation and acrosome reaction
induced by P4.
Abstract: Methicillin/multiple-resistant Staphylococcus aureus
(MRSA) are infectious bacteria that are resistant to common
antibiotics. A previous in silico study in our group has identified a
hypothetical protein SAV1226 as one of the potential drug targets. In
this study, we reported the bioinformatics characterization, as well as
cloning, expression, purification and kinetic assays of hypothetical
protein SAV1226 from methicillin/vancomycin-resistant
Staphylococcus aureus Mu50 strain. MALDI-TOF/MS analysis
revealed a low degree of structural similarity with known proteins.
Kinetic assays demonstrated that hypothetical protein SAV1226 is
neither a domain of an ATP dependent dihydroxyacetone kinase nor
of a phosphotransferase system (PTS) dihydroxyacetone kinase,
suggesting that the function of hypothetical protein SAV1226 might
be misannotated on public databases such as UniProt and
InterProScan 5.
Abstract: Because blueberries are worldwide recognized as a
good source of beneficial components, their consumption has
increased in the past decades, and so have the scientific works about
their properties. Hence, this work was undertaken to evaluate the
effect of some production and conservation factors on the properties
of blueberries from cultivar Bluecrop. The physical and chemical
analyses were done according to established methodologies and then
all data was treated using software SPSS for assessment of the
possible differences among the factors investigated and/or the
correlations between the variables at study. The results showed that
location of production influenced some of the berries properties
(caliber, sugars, antioxidant activity, color and texture) and that the
age of the bushes was correlated with moisture, sugars and acidity, as
well as lightness. On the other hand, altitude of the farm only was
correlated to sugar content. With regards to conservation, it
influenced only anthocyanins content and DPPH antioxidant activity.
Finally, the type of extract and the order of extraction had a
pronounced influence on all the phenolic properties evaluated.
Abstract: A novel design technique employing CMOS Current
Feedback Operational Amplifier (CFOA) is presented. The feature of
consumption very low power in designing pseudo-OTA is used to
decreasing the total power consumption of the proposed CFOA. This
design approach applies pseudo-OTA as input stage cascaded with
buffer stage. Moreover, the DC input offset voltage and harmonic
distortion (HD) of the proposed CFOA are very low values compared
with the conventional CMOS CFOA due to the symmetrical input
stage. P-Spice simulation results are obtained using 0.18μm MIETEC
CMOS process parameters and supply voltage of ±1.2V, 50μA
biasing current. The p-spice simulation shows excellent improvement
of the proposed CFOA over existing CMOS CFOA. Some of these
performance parameters, for example, are DC gain of 62. dB, openloop
gain bandwidth product of 108 MHz, slew rate (SR+) of
+71.2V/μS, THD of -63dB and DC consumption power (PC) of
2mW.
Abstract: The problem of finding control laws for underactuated
systems has attracted growing attention since these systems are
characterized by the fact that they have fewer actuators than the
degrees of freedom to be controlled. The acrobot, which is a planar
two-link robotic arm in the vertical plane with an actuator at the elbow
but no actuator at the shoulder, is a representative in underactuated
systems. In this paper, the dynamic model of the acrobot is
implemented using Mathworks’ Simscape. And the sliding mode
control is constructed using MATLAB and Simulink.
Abstract: We present a gas-liquid microfluidic system as a
reactor to obtain magnetite nanoparticles with an excellent degree of
control regarding their crystalline phase, shape and size. Several
types of microflow approaches were selected to prevent nanomaterial
aggregation and to promote homogenous size distribution. The
selected reactor consists of a mixer stage aided by ultrasound waves
and a reaction stage using a N2-liquid segmented flow to prevent
magnetite oxidation to non-magnetic phases. A milli-fluidic reactor
was developed to increase the production rate where a magnetite
throughput close to 450 mg/h in a continuous fashion was obtained.
Abstract: Potassium borates, which are widely used in welding
and metal refining industry, as a lubricating oil additive, cement
additive, fiberglass additive and insulation compound, are one of the
important groups of borate minerals. In this study the production of a
potassium borate mineral via hydrothermal method is aimed. The
potassium source of potassium nitrate (KNO3) was used along with a
sodium source of sodium hydroxide (NaOH) and boron source of
boric acid (H3BO3). The constant parameters of reaction temperature
and reaction time were determined as 80°C and 1 h, respectively. The
molar ratios of 1:1:3 (as KNO3:NaOH:H3BO3), 1:1:4, 1:1:5, 1:1:6
and 1:1:7 were used. Following the synthesis the identifications of
the produced products were conducted by X-Ray Diffraction (XRD),
Fourier Transform Infrared Spectroscopy (FT-IR) and Raman
Spectroscopy. The results of the experiments and analysis showed in
the ratio of 1:1:6, the Santite mineral with powder diffraction file
number (pdf no.) of 01-072-1688, which is known as potassium
pentaborate (KB5O8·4H2O) was synthesized as best.
Abstract: Some plants of genus Schinus have been used in the
folk medicine as topical antiseptic, digestive, purgative, diuretic,
analgesic or antidepressant, and also for respiratory and urinary
infections. Chemical composition of essential oils of S. molle and S.
terebinthifolius had been evaluated and presented high variability
according with the part of the plant studied and with the geographic
and climatic regions. The pharmacological properties, namely
antimicrobial, anti-tumoural and anti-inflammatory activities are
conditioned by chemical composition of essential oils. Taking into
account the difficulty to infer the pharmacological properties of
Schinus essential oils without hard experimental approach, this work
will focus on the development of a decision support system, in terms
of its knowledge representation and reasoning procedures, under a
formal framework based on Logic Programming, complemented with
an approach to computing centered on Artificial Neural Networks
and the respective Degree-of-Confidence that one has on such an
occurrence.