Abstract: Although, arsenic trioxide has been the subject of
toxicological research, in vitro cytotoxicity and genotoxicity studies
using relevant cell models and uniform methodology are not well
elucidated. Hence, the aim of the present study was to evaluate the
cytotoxicity and genotoxicity induced by arsenic trioxide in human
keratinocytes (HaCaT) using the MTT [3-(4, 5-dimethylthiazol-2-yl)-
2,5-diphenyltetrazolium bromide] and alkaline single cell gel
electrophoresis (Comet) assays, respectively. Human keratinocytes
were treated with different doses of arsenic trioxide for 4 h prior to
cytogenetic assessment. Data obtained from the MTT assay indicated
that arsenic trioxide significantly reduced the viability of HaCaT cells
in a dose-dependent manner, showing an IC50 value of 34.18 ± 0.6
μM. Data generated from the comet assay also indicated a significant
dose-dependent increase in DNA damage in HaCaT cells associated
with arsenic trioxide exposure. We observed a significant increase in
comet tail length and tail moment, showing an evidence of arsenic
trioxide -induced genotoxic damage in HaCaT cells. This study
confirms that the comet assay is a sensitive and effective method to
detect DNA damage caused by arsenic.
Abstract: Generally the natural environment is made up of air,
water and soil. The release of emission of industrial waste into
anyone of the components of the environment causes pollution.
Industrial pollution significantly threatens the inherent right of
people, to the enjoyment of a safe and secure environment. The aim
of this paper is to assess the effect of environmental pollution and
health risks of residents living near Ewekoro cement factory. The
research made use of IKONOS imagery for Geographical
Information System (GIS) to buffer and extract buildings that are less
than 1km to the factory, within 1km to 5km and above 5km to the
factory. Also questionnaire was used to elicit information on the
socio-economic factors, effect of environmental pollution on
residents and measures adopted to control industrial pollution on the
residents. Findings show that most buildings that fall between less
than 1km and 1km to 5km to the factory have high health risk in the
study area. The study recommended total relocation for the residents
of the study area to reduce health risk problems.
Abstract: This paper presents small signal stability study carried
over the 140-Bus, 31-Machine, 5-Area MEPE system and validated
on free and open source software: PSAT. Well-established linearalgebra
analysis, eigenvalue analysis, is employed to determine the
small signal dynamic behavior of test system. The aspects of local
and interarea oscillations which may affect the operation and
behavior of power system are analyzed. Eigenvalue analysis is carried
out to investigate the small signal behavior of test system and the
participation factors have been determined to identify the
participation of the states in the variation of different mode shapes.
Also, the variations in oscillatory modes are presented to observe the
damping performance of the test system.
Abstract: Random epistemologies and hash tables have garnered
minimal interest from both security experts and experts in the last
several years. In fact, few information theorists would disagree with
the evaluation of expert systems. In our research, we discover how
flip-flop gates can be applied to the study of superpages. Though
such a hypothesis at first glance seems perverse, it is derived from
known results.
Abstract: For the treatment of acute and chronic lung diseases it is preferred to deliver medicaments by inhalation. The drug is delivered directly to tracheobronchial tree. This way allows the given medicament to get directly into the place of action and it makes rapid onset of action and maximum efficiency. The transport of aerosol particles in the particular part of the lung is influenced by their size, anatomy of the lungs, breathing pattern and airway resistance. This article deals with calculation of airway resistance in the lung model of Horsfield. It solves the problem of determination of the pressure losses in bifurcation and thus defines the pressure drop at a given location in the bronchial tree. The obtained data will be used as boundary conditions for transport of aerosol particles in a central part of bronchial tree realized by Computational Fluid Dynamics (CFD) approach. The results obtained from CFD simulation will allow us to provide information on the required particle size and optimal inhalation technique for particle transport into particular part of the lung.
Abstract: The 3D body movement signals captured during
human-human conversation include clues not only to the content of
people’s communication but also to their culture and personality.
This paper is concerned with automatic extraction of this information
from body movement signals. For the purpose of this research, we
collected a novel corpus from 27 subjects, arranged them into groups
according to their culture. We arranged each group into pairs and
each pair communicated with each other about different topics.
A state-of-art recognition system is applied to the problems of
person, culture, and topic recognition. We borrowed modeling,
classification, and normalization techniques from speech recognition.
We used Gaussian Mixture Modeling (GMM) as the main technique
for building our three systems, obtaining 77.78%, 55.47%, and
39.06% from the person, culture, and topic recognition systems
respectively. In addition, we combined the above GMM systems with
Support Vector Machines (SVM) to obtain 85.42%, 62.50%, and
40.63% accuracy for person, culture, and topic recognition
respectively.
Although direct comparison among these three recognition
systems is difficult, it seems that our person recognition system
performs best for both GMM and GMM-SVM, suggesting that intersubject
differences (i.e. subject’s personality traits) are a major
source of variation. When removing these traits from culture and
topic recognition systems using the Nuisance Attribute Projection
(NAP) and the Intersession Variability Compensation (ISVC)
techniques, we obtained 73.44% and 46.09% accuracy from culture
and topic recognition systems respectively.
Abstract: Arising problems of countries’ public finances, social
and demographic changes motivate scientific and policy debates on
public spending size, structure and efficiency in order to meet the
changing needs of society and business. The concept of sustainable
development poses new challenges for scientists and policy-makers
in the field of public finance. This paper focuses on the investigation
of the relationship between government expenditure and country’s
economic development in the context of sustainable development.
Empirical analysis focuses on the data of the European Union (except
Croatia and Luxemburg) countries. The study covers 2003 – 2012
years, using annual cross-sectional data. Summarizing the research
results, it can be stated that governments should pay more attention to
the needs that ensure sustainable development in the long-run when
formulating public expenditure policy, particularly in the field of
environment protection.
Abstract: Recently, universities are increasingly consuming
energy to support various activities. A large population of staff and
students in Malaysian universities has led to excessive energy
consumption which directly gives an impact to the environment. The
key question then ascended “How well is an energy management
(EM) been practiced in universities without taking the Critical
Success Factors (CSFs) into consideration to ensure the management
of university achieves the goals in reducing energy consumption.
Review on past literature is carried out to establish CSFs for EM best
practices. Thus, this paper highlighted the CSFs which have to be
focused on by management of university to successfully measure the
EM implementation and its performance. At the end of this paper, a
theoretical framework is developed for EM success factors towards
sustainable university.
Abstract: An experiment was conducted to determine the effect
of pollination on seed quality of rapeseed in Chitwan, Nepal during
2012-2013. The experiment was designed in Randomized Complete
Block with four replications and five treatments. The rapeseed plots
were caged with mosquito nets at 10% flowering except natural
pollination. Two-framed colonies of Apis mellifera L. and Apis
cerana F. were introduced separately for pollination, and control plot
caged without pollinators. The highest germination percent was
observed on Apis cerana F. pollinated plot seeds (90.50%
germination) followed by Apis mellifera L. pollinated plots (87.25 %)
and lowest on control plots (42.00% germination) seeds. Similarly,
seed test weight of Apis cerana F. pollinated plots (3.22 gm/ 1000
seed) and Apis mellifera L. pollinated plots (2.93 gm/1000 seed) were
and lowest on control plots (2.26 gm/ 1000 seed) recorded. Likewise,
oil content was recorded highest on pollinated by Apis cerana F.
(36.1%) followed by pollinated by Apis mellifera L. (35.4%) and
lowest on control plots (32.8%). This study clearly indicated
pollination increases the seed quality of rapeseed and therefore,
management of honeybee is necessary for producing higher quality of
rapeseed under Chitwan condition.
Abstract: The concentration levels of six heavy metals (Cd, Cr,
Fe, Ni, Pb and Zn) and two mineral elements (Ca and Mg) were
determined in soil samples collected from the vicinity of two auto
mechanic workshops in Sabon-Gari, Kaduna state, Nigeria, using
Atomic Absorption Spectrometry (AAS), in order to compare the
gradation of their concentrations with distance and depth of soil from
the workshop sites. At site 1, concentrations of Lead, Chromium, Iron
and Zinc were generally found to be above the World Health
Organization limits, while those of Nickel and Cadmium fell within
the limits. Iron had the highest concentration with a range of 176.274
ppm to 489.127 ppm at depths of 5 cm to 15 cm and a distance range
of 5 m to 15 m, while the concentration of cadmium was least with a
range of 0.001 ppm to 0.008 ppm at similar depth and distance
ranges. In addition, there was more of calcium (11.521 ppm to
121.709 ppm), in all the samples, than magnesium (11.293 ppm to
21.635 ppm). Similar results were obtained for site II. The
concentrations of all the metals analyzed showed a downward
gradient with increase in depth and distance from both workshop sites
except for iron and zinc at site 2. The immediate and remote
implications of these findings on the biota are discussed.
Abstract: Neurons in the nervous system communicate with
each other by producing electrical signals called spikes. To
investigate the physiological function of nervous system it is essential
to study the activity of neurons by detecting and sorting spikes in the
recorded signal. In this paper a method is proposed for considering
the spike sorting problem which is based on the nonlinear modeling
of spikes using exponential autoregressive model. The genetic
algorithm is utilized for model parameter estimation. In this regard
some selected model coefficients are used as features for sorting
purposes. For optimal selection of model coefficients, self-organizing
feature map is used. The results show that modeling of spikes with
nonlinear autoregressive model outperforms its linear counterpart.
Also the extracted features based on the coefficients of exponential
autoregressive model are better than wavelet based extracted features
and get more compact and well-separated clusters. In the case of
spikes different in small-scale structures where principal component
analysis fails to get separated clouds in the feature space, the
proposed method can obtain well-separated cluster which removes
the necessity of applying complex classifiers.
Abstract: The aim of this study is to evaluate the effects of the
laser and partial vibration stimulation on the mice tibia with
morphological characteristics. Twenty female C57BL/6 mice (12
weeks old) were used for the experiment. The study was carried out on
four groups of animals each consisting of five mice. Four groups of
mice were ovariectomized. Animals were scanned at 0 and 2 weeks
after ovariectomy by using micro computed tomography to estimate
morphological characteristics of tibial trabecular bone. Morphological
analysis showed that structural parameters of multi-stimuli group
appear significantly better phase in BV/TV, BS/BV, Tb.Th, Tb.N,
Tb.Sp, and Tb.pf than single stimulation groups. However, single
stimulation groups didn’t show significant effect on tibia with Sham
group. This study suggests that multi-stimuli may restrain the change
as the degenerate phase on osteoporosis in the mice tibia.
Abstract: The legends about “user-friendly” and “easy-to-use”
birotical tools (computer-related office tools) have been spreading
and misleading end-users. This approach has led us to the extremely
high number of incorrect documents, causing serious financial losses
in the creating, modifying, and retrieving processes. Our research
proved that there are at least two sources of this underachievement:
(1) The lack of the definition of the correctly edited, formatted
documents. Consequently, end-users do not know whether their
methods and results are correct or not. They are not aware of their
ignorance. They are so ignorant that their ignorance does not allow
them to realize their lack of knowledge. (2) The end-users’ problem
solving methods. We have found that in non-traditional programming
environments end-users apply, almost exclusively, surface approach
metacognitive methods to carry out their computer related activities,
which are proved less effective than deep approach methods.
Based on these findings we have developed deep approach
methods which are based on and adapted from traditional
programming languages. In this study, we focus on the most popular
type of birotical documents, the text based documents. We have
provided the definition of the correctly edited text, and based on this
definition, adapted the debugging method known in programming.
According to the method, before the realization of text editing, a
thorough debugging of already existing texts and the categorization
of errors are carried out. With this method in advance to real text
editing users learn the requirements of text based documents and also
of the correctly formatted text.
The method has been proved much more effective than the
previously applied surface approach methods. The advantages of the
method are that the real text handling requires much less human and
computer sources than clicking aimlessly in the GUI (Graphical User
Interface), and the data retrieval is much more effective than from
error-prone documents.
Abstract: Diffusion stills have been effective in water
desalination. The present work represents a model of the distillation
process by using vertical single-effect diffusion stills. A semianalytical
model has been developed to model the process. A
software computer code using Engineering Equation Solver EES
software has been developed to solve the equations of the developed
model. An experimental setup has been constructed, and used for the
validation of the model. The model is also validated against former
literature results. The results obtained from the present experimental
test rig, and the data from the literature, have been compared with the
results of the code to find its best range of validity. In addition, a
parametric analysis of the system has been developed using the
model to determine the effect of operating conditions on the system's
performance. The dominant parameters that affect the productivity of
the still are the hot plate temperature that ranges from (55- 90°C) and
feed flow rate in range of (0.00694-0.0211 kg/m2-s).
Abstract: PLA emerged as a promising polymer because of its
property as a compostable, biodegradable thermoplastic made from
renewable sources. PLA can be polymerized from monomers
(Lactide or Lactic acid) obtained by fermentation processes from
renewable sources such as corn starch or sugarcane. For PLA
synthesis, ring opening polymerization (ROP) of Lactide monomer is
one of the preferred methods. In the literature, the technique mainly
developed for ROP of PLA is based on metal/bimetallic catalyst (Sn,
Zn and Al) or other organic catalysts in suitable solvent. However,
the PLA synthesized using such catalysts may contain trace elements
of the catalyst which may cause toxicity. This work estimated the
usefulness and drawbacks of using different catalysts as well as effect
of alternative energies and future aspects for PLA production.
Abstract: The distribution networks are often exposed to harmful
incidents which can halt the electricity supply of the customer. In this
context, we studied a real case of a critical zone of the Tunisian
network which is currently characterized by the dysfunction of its
plan of protection. In this paper, we were interested in the
harmonization of the protection plan settings in order to ensure a
perfect selectivity and a better continuity of service on the whole of
the network.
Abstract: Geometric and mechanical properties all influence the
resistance of RC structures and may, in certain combination of
property values, increase the risk of a brittle failure of the whole
system.
This paper presents a statistical and probabilistic investigation on
the resistance of RC beams designed according to Eurocodes 2 and 8,
and subjected to multiple failure modes, under both the natural
variation of material properties and the uncertainty associated with
cross-section and transverse reinforcement geometry. A full
probabilistic model based on JCSS Probabilistic Model Code is
derived. Different beams are studied through material nonlinear
analysis via Monte Carlo simulations. The resistance model is
consistent with Eurocode 2. Both a multivariate statistical evaluation
and the data clustering analysis of outcomes are then performed.
Results show that the ultimate load behaviour of RC beams
subjected to flexural and shear failure modes seems to be mainly
influenced by the combination of the mechanical properties of both
longitudinal reinforcement and stirrups, and the tensile strength of
concrete, of which the latter appears to affect the overall response of
the system in a nonlinear way. The model uncertainty of the
resistance model used in the analysis plays undoubtedly an important
role in interpreting results.
Abstract: The main aim of this article is to present a balance of the decade of Polish air transport market in the European Union having taking into account selected entities of the aviation market. This article analyzes the functioning of the Polish air transport market after the Polish accession to the European Union. During the study two main areas were pointed: shipping activity and activity of the airports. The most important benefits of integration and the benefits of introducing of the open sky policy were indicated. The last part of the article presents the perspectives of development of air traffic.
Abstract: This study was conducted to investigate the effect of
the antioxidant activity of germinated African Yam Bean (AYB) on
oxidative stress markers in alloxan induced diabetic rat. Rats were
randomized into three groups; control, diabetic and germinated AYB
– treated diabetic rats. The Total phenol and flavonoid content and
DPPH radical scavenging activity before and after germination were
investigated. The glucose level, lipid peroxidation and reduced
glutathione of the animals were also determined using standard
technique for four weeks. Germination increased the total phenol,
flavonoid and antioxidant activity of AYB extract by 19.14%,
32.28% and 57.25% respectively. The diabetic rats placed on
germinated AYB diet had a significant decrease in the blood glucose
and lipid peroxidation with a corresponding increase in glutathione
(p
Abstract: Thin ZnO films are deposited on glass substrates via
sol–gel method and dip-coating. The films are prepared from zinc
acetate dehydrate as a starting reagent. After that the as-prepared
ZnO sol is aged for different periods (0, 1, 3, 5, 10, 15 and 30 days).
Nanocrystalline thin films are deposited from various sols. The
effect ZnO sols aging time on the structural and photocatalytic
properties of the films is studied. The films surface is studied by
Scanning Electron Microscopy. The effect of the aging time of the
starting solution is studied in the photocatalytic degradation of
Reactive Black 5 (RB5) by UV-vis spectroscopy. The experiments
are conducted upon UV-light illumination and in complete darkness.
The variation of the absorption spectra shows the degradation of RB5
dissolved in water, as a result of the reaction, occurring on the surface
of the films and promoted by UV irradiation. The initial
concentrations of dye (5, 10 and 20 ppm) and the effect of the aging
time are varied during the experiments. The results show, that the
increasing aging time of starting solution with respect to ZnO
generally promotes photocatalytic activity. The thin films obtained
from ZnO sol, which is aged 30 days have best photocatalytic
degradation of the dye (97,22%) in comparison with the freshly
prepared ones (65,92%). The samples and photocatalytic
experimental results are reproducible. Nevertheless, all films exhibit
a substantial activity in both UV light and darkness, which is
promising for the development of new ZnO photocatalysts by sol-gel
method.