Abstract: Purpose: The study aimed to assess the depressant or
antidepressant effects of several Nonsteroidal Anti-Inflammatory
Drugs (NSAIDs) in mice: the selective cyclooxygenase-2 (COX-2)
inhibitor meloxicam, and the non-selective COX-1 and COX-2
inhibitors lornoxicam, sodium metamizole, and ketorolac. The
current literature data regarding such effects of these agents are
scarce.
Materials and methods: The study was carried out on NMRI mice
weighing 20-35 g, kept in a standard laboratory environment. The
study was approved by the Ethics Committee of the University of
Medicine and Pharmacy „Carol Davila”, Bucharest. The study agents
were injected intraperitoneally, 10 mL/kg body weight (bw) 1 hour
before the assessment of the locomotor activity by cage testing (n=10
mice/ group) and 2 hours before the forced swimming tests (n=15).
The study agents were dissolved in normal saline (meloxicam,
sodium metamizole), ethanol 11.8% v/v in normal saline (ketorolac),
or water (lornoxicam), respectively. Negative and positive control
agents were also given (amitryptilline in the forced swimming test).
The cage floor used in the locomotor activity assessment was divided
into 20 equal 10 cm squares. The forced swimming test involved
partial immersion of the mice in cylinders (15/9cm height/diameter)
filled with water (10 cm depth at 28C), where they were left for 6
minutes. The cage endpoint used in the locomotor activity assessment
was the number of treaded squares. Four endpoints were used in the
forced swimming test (immobility latency for the entire 6 minutes,
and immobility, swimming, and climbing scores for the final 4
minutes of the swimming session), recorded by an observer that was
„blinded” to the experimental design. The statistical analysis used the
Levene test for variance homogeneity, ANOVA and post-hoc
analysis as appropriate, Tukey or Tamhane tests.
Results: No statistically significant increase or decrease in the
number of treaded squares was seen in the locomotor activity
assessment of any mice group. In the forced swimming test,
amitryptilline showed an antidepressant effect in each experiment, at
the 10 mg/kg bw dosage. Sodium metamizole was depressant at 100
mg/kg bw (increased the immobility score, p=0.049, Tamhane test),
but not in lower dosages as well (25 and 50 mg/kg bw). Ketorolac
showed an antidepressant effect at the intermediate dosage of 5
mg/kg bw, but not so in the dosages of 2.5 and 10 mg/kg bw,
respectively (increased the swimming score, p=0.012, Tamhane test).
Meloxicam and lornoxicam did not alter the forced swimming
endpoints at any dosage level.
Discussion: 1) Certain NSAIDs caused changes in the forced
swimming patterns without interfering with locomotion. 2) Sodium
metamizole showed a depressant effect, whereas ketorolac proved
antidepressant. Conclusion: NSAID-induced mood changes are not
class effects of these agents and apparently are independent of the
type of inhibited cyclooxygenase (COX-1 or COX-2).
Disclosure: This paper was co-financed from the European Social
Fund, through the Sectorial Operational Programme Human Resources Development 2007-2013, project number POSDRU /159
/1.5 /S /138907 "Excellence in scientific interdisciplinary research,
doctoral and postdoctoral, in the economic, social and medical fields
-EXCELIS", coordinator The Bucharest University of Economic
Studies.
Abstract: The objectives of this study are to study Chinese
tourist’s Behaviors towards travel and shopping in Bangkok. The
research methodology was a quantitative research. The sample of this
research was 400 Chinese tourists in Bangkok chosen by the
accidental sampling and the purposive sampling. Inferential Statistics
Analysis by using the Chi-square statistics. As for the results of this
study the researcher found that differences between personal, social
and cultural information, i.e., gender, age, place of residence,
educational level, occupation, income, family, and main objectives of
tourism with behaviors of Chinese tourists in Bangkok towards travel
and shopping in Bangkok.
Abstract: In Hungary, the society has changed a lot for the past
25 years, and these changes could be detected in educational
situations as well. The number and the intensity of conflicts have
been increased in most fields of life, as well as at schools. Teachers
have difficulties to be able to handle school conflicts. What is more,
the new net generation, generation Z has values and behavioural
patterns different from those of the previous one, which might
generate more serious conflicts at school, especially with teachers
who were mainly socialising in a traditional teacher – student
relationship.
In Hungary, the bill CCIV of 2011 declared the foundation of
Institutes of Teacher Training in higher education institutes. One of
the tasks of the Institutes is to survey the competences and needs of
teachers working in public education and to provide further trainings
and services for them according to their needs and requirements. This
job is supported by the Social Renewal Operative Programs 4.1.2.B.
The professors of a college carried out a questionnaire and surveyed
the needs and the requirements of teachers working in the region.
Based on the results, the professors of the Institute of Teacher
Training decided to meet the requirements of teachers and to launch
short teacher further training courses in spring 2015. One of the
courses is going to focus on school conflict management through
mediation.
The aim of the pilot course is to provide conflict management
techniques for teachers and to present different mediation techniques
to them. The theoretical part of the course (5 hours) will enable
participants to understand the main points and the advantages of
mediation, while the practical part (10 hours) will involve teachers in
role plays to learn how to cope with conflict situations applying
mediation. We hope if conflicts could be reduced, it would influence
school atmosphere in a positive way and the teaching – learning
process could be more successful and effective.
Abstract: Networking is important among students to achieve
better understanding. Social networking plays an important role in the
education. Realizing its huge potential, various organizations,
including institutions of higher learning have moved to the area of
social networks to interact with their students especially through
Facebook. Therefore, measuring the effectiveness of Facebook as a
learning tool has become an area of interest to academicians and
researchers. Therefore, this study tried to integrate and propose new
theoretical and empirical evidences by linking the western idea of
adopting Facebook as an alternative learning platform from a
Malaysian perspective. This study, thus, aimed to fill a gap by being
among the pioneering research that tries to study the effectiveness of
adopting Facebook as a learning platform across other cultural
settings, namely Malaysia. Structural equation modeling was
employed for data analysis and hypothesis testing. This study finding
has provided some insights that would likely affect students’
awareness towards using Facebook as an alternative learning
platform in the Malaysian higher learning institutions. At the end,
future direction is proposed.
Abstract: This paper analyzes the conceptual framework of three
statistical methods, multiple regression, path analysis, and structural
equation models. When establishing research model of the statistical
modeling of complex social phenomenon, it is important to know the
strengths and limitations of three statistical models. This study
explored the character, strength, and limitation of each modeling and
suggested some strategies for accurate explaining or predicting the
causal relationships among variables. Especially, on the studying of
depression or mental health, the common mistakes of research
modeling were discussed.
Abstract: Agro-industry is one of major industries that have
strong impacts on national economic incomes, growth, stability, and
sustainable development. Moreover, this industry also has strong
influences on social, cultural and political issues. Furthermore, this
industry, as producing primary and secondary products, is facing
challenges from such diverse factors such as demand inconsistency,
intense international competition, technological advancements and
new competitors. In order to maintain and to improve industry’s
competitiveness in both domestics and international markets, science
and technology are key factors. Besides hard sciences and
technologies, modern industrial engineering concepts such as Just in
Time (JIT) Total Quality Management (TQM), Quick Response
(QR), Supply Chain Management (SCM) and Lean can be very
effective to support to increase efficiency and effectiveness of these
agricultural products on world stage. Onion is one of Thailand’s
major export products which bring back national incomes. But, it is
also facing challenges in many ways. This paper focused its interests
in onion packing process and its related activities such as storage and
shipment from one of major packing plant and storage in Mae Wang
District, Chiang Mai, Thailand, by applying Toyota Production
System (TPS) or Lean concepts, to improve process capability
throughout the entire packing and distribution process which will be
profitable for the whole onion supply chain. And it will be beneficial
to other related agricultural products in Thailand and other ASEAN
countries.
Abstract: During the post-Civil War era, the city of Nashville,
Tennessee, had the highest mortality rate in the United States. The
elevated death and disease rates among former slaves were
attributable to lack of quality healthcare. To address the paucity of
healthcare services, Meharry Medical College, an institution with the
mission of educating minority professionals and serving the
underserved population, was established in 1876.
Purpose: The social ecological framework and partial least squares
(PLS) path modeling were used to quantify the impact of
socioeconomic status and adverse health outcome on primary care
professionals serving the disadvantaged community. Thus, the study
results could demonstrate the accomplishment of the College’s
mission of training primary care professionals to serve in underserved
areas.
Methods: Various statistical methods were used to analyze alumni
data from 1975 – 2013. K-means cluster analysis was utilized to
identify individual medical and dental graduates in the cluster groups
of the practice communities (Disadvantaged or Non-disadvantaged
Communities). Discriminant analysis was implemented to verify the
classification accuracy of cluster analysis. The independent t-test was
performed to detect the significant mean differences of respective
clustering and criterion variables. Chi-square test was used to test if
the proportions of primary care and non-primary care specialists are
consistent with those of medical and dental graduates practicing in
the designated community clusters. Finally, the PLS path model was
constructed to explore the construct validity of analytic model by
providing the magnitude effects of socioeconomic status and adverse
health outcome on primary care professionals serving the
disadvantaged community.
Results: Approximately 83% (3,192/3,864) of Meharry Medical
College’s medical and dental graduates from 1975 to 2013 were
practicing in disadvantaged communities. Independent t-test confirmed the content validity of the cluster analysis model. Also, the
PLS path modeling demonstrated that alumni served as primary care
professionals in communities with significantly lower socioeconomic
status and higher adverse health outcome (p < .001). The PLS path
modeling exhibited the meaningful interrelation between primary
care professionals practicing communities and surrounding
environments (socioeconomic statues and adverse health outcome),
which yielded model reliability, validity, and applicability.
Conclusion: This study applied social ecological theory and
analytic modeling approaches to assess the attainment of Meharry
Medical College’s mission of training primary care professionals to
serve in underserved areas, particularly in communities with low
socioeconomic status and high rates of adverse health outcomes. In
summary, the majority of medical and dental graduates from Meharry
Medical College provided primary care services to disadvantaged
communities with low socioeconomic status and high adverse health
outcome, which demonstrated that Meharry Medical College has
fulfilled its mission. The high reliability, validity, and applicability of
this model imply that it could be replicated for comparable
universities and colleges elsewhere.
Abstract: Introduction: There are multiple social, individual and
cultural factors that influence an individual’s decision to adopt family
planning methods especially among non-users in patriarchal societies
like Pakistan. Non-users, if targeted efficiently, can contribute
significantly to country’s CPR. A research study showed that nonusers
if convinced to adopt lactational amenorrhea method can shift
to long term methods in future. Research shows that if non users are
targeted efficiently a 59% reduction in unintended pregnancies in
Saharan Africa and South-Central and South-East Asia is anticipated.
Methods: We did secondary data analysis on Pakistan
Demographic Heath Survey (2012-13) dataset. Use of contraception
(never-use/ever-use) was the outcome variable. At univariate level
Chi-square/Fisher Exact test was used to assess relationship of
baseline covariates with contraception use. Then variables to be
incorporated in the model were checked for multicollinearity,
confounding and interaction. Then binary logistic regression (with an
urban-rural stratification) was done to find relationship between
contraception use and baseline demographic and social variables.
Results: The multivariate analyses of the study showed that
younger women (≤ 29 years)were more prone to be never users as
compared to those who were >30 years and this trend was seen in
urban areas (AOR 1.92, CI 1.453-2.536) as well as rural areas (AOR
1.809, CI 1.421-2.303). While looking at regional variation, women
from urban Sindh (AOR 1.548, CI 1.142-2.099) and urban
Balochistan (AOR 2.403, CI 1.504-3.839) had more never users as
compared to other urban regions. Women in the rich wealth quintile
were more never users and this was seen both in urban and rural
localities (urban (AOR 1.106 CI .753-1.624); rural areas (AOR 1.162,
CI .887-1.524)) even though these were not statistically significant.
Women idealizing more children (>4) are more never users as
compared to those idealizing less children in both urban (AOR 1.854,
CI 1.275-2.697) and rural areas (AOR 2.101, CI 1.514-2.916).
Women who never lost a pregnancy were more inclined to be nonusers
in rural areas (AOR 1.394, CI 1.127-1.723) .Women familiar
with only traditional or no method had more never users in rural areas
(AOR 1.717, CI 1.127-1.723) but in urban areas it wasn’t significant.
Women unaware of Lady Health Worker’s presence in their area
were more never users especially in rural areas (AOR 1.276, CI
1.014-1.607). Women who did not visit any care provider were more
never users (urban (AOR 11.738, CI 9.112-15.121) rural areas (AOR
7.832, CI 6.243-9.826)).
Discussion/Conclusion: This study concluded that government,
policy makers and private sector family planning programs should
focus on the untapped pool of never users (younger women from underserved provinces, in higher wealth quintiles, who desire more
children.). We need to make sure to cover catchment areas where
there are less LHWs and less providers as ignorance to modern
methods and never been visited by an LHW are important
determinants of never use. This all is in sync with previous literate
from similar developing countries.
Abstract: Theory of Mind (ToM) refers to the ability to infer
another’s mental state. With appropriate ToM, one can behave well in
social interactions. A growing body of evidence has demonstrated that
patients with temporal lobe epilepsy (TLE) may damage ToM by
affecting on regions of the underlying neural network of ToM.
However, the question of whether there is cerebral laterality for ToM
functions remains open. This study aimed to examine whether there is
cerebral lateralization for ToM abilities in TLE patients. Sixty-seven
adult TLE patients and 30 matched healthy controls (HC) were
recruited. Patients were classified into right (RTLE), left (LTLE), and
bilateral (BTLE) TLE groups on the basis of a consensus panel review
of their seizure semiology, EEG findings, and brain imaging results.
All participants completed an intellectual test and four tasks measuring
basic and advanced ToM. The results showed that, on all ToM tasks,
(1) each patient group performed worse than HC; (2) there were no
significant differences between LTLE and RTLE groups; and (3) the
BTLE group performed the worst. It appears that the neural network
responsible for ToM is distributed evenly between the cerebral
hemispheres.
Abstract: Due to rapid pressured of population growth, city has
started to lose its old tradition. City becomes congested with
uncomfortably living. Urban renewal refers orderly development of
settlements as well as land redevelopment. For this paper Chittagong
city has been selected as study area. It had a great tradition but it has
been losing its concord. Land use pattern of this place is also
haphazard due to lack of planning intervention. Renewal plan is
needed to ascertain suitable redevelopment and to recommend on
preservation of city heritage structure. The goal of this study is to
prepare a renewal plan using local planning approach. Social impact
methods have been used to achieve this goal. Both primary and
secondary data are used to achieve the goal. This study may find out
a complete solution for healthy living in old Part of city. This study
will help to preserve its tradition and makes urban lives more livable.
Abstract: The advent of social networking technologies has been
met with mixed reactions in academic and corporate circles around
the world. This study explored the influence of social network in
current era, the relation being maintained between the Social
networking site and its user by the extent of use, benefits and latest
technologies. The study followed a descriptive research design
wherein a questionnaire was used as the main research tool. The data
collected was analyzed using SPSS 16. Data was gathered from 1205
users and analyzed in accordance with the objectives of the study.
The analysis of the results seem to suggest that the majority of users
were mainly using Facebook, despite of concerns raised about the
disclosure of personal information on social network sites, users
continue to disclose huge quantity of personal information, they find
that reading privacy policy is time consuming and changes made can
result into improper settings.
Abstract: The exponential growth of social media arouses much
attention on public opinion information. The online forums, blogs,
micro blogs are proving to be extremely valuable resources and are
having bulk volume of information. However, most of the social
media data is unstructured and semi structured form. So that it is
more difficult to decipher automatically. Therefore, it is very much
essential to understand and analyze those data for making a right
decision. The online forums hotspot detection is a promising research
field in the web mining and it guides to motivate the user to take right
decision in right time. The proposed system consist of a novel
approach to detect a hotspot forum for any given time period. It uses
aging theory to find the hot terms and E-K-means for detecting the
hotspot forum. Experimental results demonstrate that the proposed
approach outperforms k-means for detecting the hotspot forums with
the improved accuracy.
Abstract: The authors propose the identification, analysis and
prognosis of the quantitative and qualitative evolution of the elderly
population in the functional urban areas. The present paper takes into
account the analysis of some representative indicators (the weight of
the elderly population, ageing index, dynamic index of economic
ageing of productive population etc.) and the elaboration of an
integrated indicator that would help differentiate the population
ageing forms in the 48 functional urban areas that were defined based
on demographic and social-economic criteria for all large and
medium cities in Romania.
Abstract: Turkish migrants constitute the largest group among
people with migration background living in Germany. Turkish
women’s labor market participation is of significant importance for
their social and economic integration to the German society. This
paper thus aims to investigate their labor market positions. Turkish
migrant women participate less in the labor market compared to men,
and are responsible for most of the housework, child care, and elderly
care. This is due to their traditional roles in the family, educational
level, insufficient knowledge of German language, and insufficient
professional experience. We strongly recommend that wide-reaching
integration policies for women are formulated, so as to encourage
participation of not only migrant women but also their husbands,
fathers and/or brothers, and natives.
Abstract: Family has a crucial role in maintaining the
physical, social and mental health of the children. Most of the
mental and anxiety problems of children reflect the complex
interpersonal situations among family members, especially parents.
In other words, anxiety problems of the children are correlated
with deficit relationships of family members and improper
childrearing styles. The parental child rearing styles leads to
positive and negative consequences which affect the children’s
mental health. Therefore, the present research was aimed to
compare the parental childrearing styles and anxiety of children
with stuttering and normal population. It was also aimed to study
the relationship between parental child rearing styles and anxiety
of children. The research sample included 54 boys with stuttering
and 54 normal boys who were selected from the children (boys) of
Tehran, Iran in the age range of 5 to 8 years in 2013. In order to
collect data, Baum-rind Childrearing Styles Inventory and Spence
Parental Anxiety Inventory were used. Appropriate descriptive
statistical methods and multivariate variance analysis and t test for
independent groups were used to test the study hypotheses.
Statistical data analyses demonstrated that there was a significant
difference between stuttering boys and normal boys in anxiety (t =
7.601, p< 0.01); but there was no significant difference between
stuttering boys and normal boys in parental childrearing styles (F =
0.129). There was also not found significant relationship between
parental childrearing styles and children anxiety (F = 0.135, p<
0.05). It can be concluded that the influential factors of children’s
society are parents, school, teachers, peers and media. So, parental
childrearing styles are not the only influential factors on anxiety of
children, and other factors including genetic, environment and
child experiences are effective in anxiety as well. Details are
discussed.
Abstract: The objective of the article was to identify the impacts of gamification on customers' behaviour. The most important applications of games in marketing and mechanisms of gamification are presented in the article. A detailed analysis of the influence of gamification on customers using two brands, Foursquare and Nike, was also presented. Research studies using auditory survey methods were carried out among 176 young respondents, who are potential targets of gamification. The studies confirmed a huge participation of young people in customer loyalty programs with relatively low participation in other gamificationbased marketing activities. The research findings clearly indicate that gamification mechanisms are the most attractive.
Abstract: The intrinsic contradictions of entrepreneurship
development and self-development strategies complicate the task of
reaching compliance between the state economic policy and the
company entrepreneurship policy: on the one hand, there is a
contradiction between the social and the competitive order within
economic order policy and on the other hand, the contradiction exists
between entrepreneurship strategy and entrepreneurship culture
within entrepreneurship policy.
Abstract: The purposes of this study are 1) to study the effects
of participatory error correction process and 2) to find out the
students’ satisfaction of such error correction process. This study is a
Quasi Experimental Research with single group, in which data is
collected 5 times preceding and following 4 experimental studies of
participatory error correction process including providing coded
indirect corrective feedback in the students’ texts with error treatment
activities. Samples include 52 2nd year English Major students,
Faculty of Humanities and Social Sciences, Suan Sunandha Rajabhat
University. Tool for experimental study includes the lesson plan of
the course; Reading and Writing English for Academic Purposes II,
and tools for data collection include 5 writing tests of short texts and
a questionnaire. Based on formative evaluation of the students’
writing ability prior to and after each of the 4 experiments, the
research findings disclose the students’ higher scores with statistical
difference at 0.00. Moreover, in terms of the effect size of such
process, it is found that for mean of the students’ scores prior to and
after the 4 experiments; d equals 0.6801, 0.5093, 0.5071, and 0.5296
respectively. It can be concluded that participatory error correction
process enables all of the students to learn equally well and there is
improvement in their ability to write short texts. Finally the students’
overall satisfaction of the participatory error correction process is in
high level (Mean = 4.39, S.D. = 0.76).
Abstract: Typically, virtual communities exhibit the well-known
phenomenon of participation inequality, which means that only a
small percentage of users is responsible of the majority of
contributions. However, the sustainability of the community requires
that the group of active users must be continuously nurtured with new
users that gain expertise through a participation process. This paper
analyzes the time evolution of Open Source Software (OSS)
communities, considering users that join/abandon the community
over time and several topological properties of the network when
modeled as a social network. More specifically, the paper analyzes
the role of those users rejoining the community and their influence in
the global characteristics of the network.
Abstract: Our globalizing world has become almost a small
village and everyone can access any information at any time.
Everyone lets each other know who does whatever in which place.
We can learn which social events occur in which place in the world.
From the perspective of education, the course notes that a lecturer use
in lessons in a university in any state of America can be examined by
a student studying in a city of Africa or the Far East. This dizzying
communication we have mentioned happened thanks to fast
developments in computer and internet technologies. While these
developments occur in the world, Turkey that has a very large young
population and whose electronic infrastructure rapidly improves has
also been affected by these developments. Nowadays, mobile devices
have become common and thus, it causes to increase data traffic in
social networks. This study was carried out on students in the
different age groups in Selcuk University Vocational School of
Technical Sciences, the Department of Computer Technology.
Students’ opinions about the use of internet and social media were
obtained. The features such as using the Internet and social media
skills, purposes, operating frequency, accessing facilities and tools,
social life and effects on vocational education and so forth were
explored. The positive effects and negative effects of both internet
and social media use on the students in this department and findings
are evaluated from different perspectives and results are obtained. In
addition, relations and differences were found out statistically.