Abstract: Feed oil samples which are used as mixed feed raw
material were taken from six different feed factories in March, May
and July. All factories make production in Konya, Turkey and all of
the samples were crude soybean oils. Physical and chemical analyses,
free radical scavenger effect, and total phenol content were
determined on these oil samples. Moisture (M) content was found
between 0.10-22.23%, saponification number (SF) was determined
143.13 to 167.93 KOH/kg, free fatty acidity (FFA) was varied 0.73 to
35.00%, peroxide value (PV) was found between 1.53 and 28.43
meq/kg, unsaponifiable matter (USM) was determined from 0.40 to
17.10%, viscosity (V) was found between 34.30 and 625.67 mPas,
sediment (S) amount was determined between 0.60-18.16%, free
radical scavenger effect (FRSE) was varied 20.7 to 43.04% inhibition
of the extract and total phenol (TPC) content was found between 1.20
and 2.69mg/L extract. Different results were found between months
and factories.
Abstract: Forward Osmosis (FO) polyamide thin-film composite
membranes have been prepared by interfacial polymerization using
commercial UF polyethersulfoneas membrane support. Different
interfacial polymerization times (10s, 30s and 60s) in the organic
solution containing trimesoyl chloride (TMC) at constant m-phenylenediamine
(MPD) concentration (2% w/v) were studied. The
synthesized polyamide membranes then tested for treatment of
natural organic matter (NOM) and compared to commercial Cellulose
TriAcetate (CTA) membrane. It was found that membrane prepared
with higher reaction time (30s and 60s) exhibited better membrane
performance (flux and humic acid removal) over commercial CTA
membrane.
Abstract: Depositional environment and source potential of the
different organic-rich levels of Devonian age (up to 990m thick) from
the onshore EC-1 well (Southern Tunisia) were investigated based on
the analysis of more than 130 cutting samples by different
geochemical techniques (Rock-Eval pyrolysis, GC-MS). The
obtained results including Rock Eval Pyrolysis data and biomarker
distribution (terpanes, steranes and aromatics) have been used to
describe the depositional environment and to assess the thermal
maturity of the Devonian organic matter. These results show that the
Emsian deposits exhibit poor to fair TOC contents. The associated
organic matter is composed of mixed kerogen (type II/III), as
indicated by the predominance of C29 steranes over C27 and C28
homologous, that was deposited in a slightly reduced environment
favoring organic matter preservation. Thermal maturity assessed from
Tmax, TNR and MPI-1 values shows a mature stage of organic
matter. The Middle Devonian (Eifelian) shales are rich in type II
organic matter that was deposited in an open marine depositional
environment. The TOC values are high and vary between 2 and 7%
indicating good to excellent source rock. The relatively high HI
values (reaching 547 mg HC/g TOC) and the low values of t19/t23
tricyclic terpane ratio (< 0.2) confirm the marine origin of the organic
matter (type II). During the Upper Devonian, the organic matter was
deposited under variable redox conditions, oxic to suboxic which is
clearly indicated by the low C35/C34 hopanes ratio, immature to
marginally mature with the vitrinite reflectance ranging from 0.5 to
0.7 Ro and Tmax value of 426°C-436 °C and the TOC values range
between 0.8% to 4%.
Abstract: The mechanisms underlying the association between
obesity and asthma may be related to a decreased immunological
tolerance induced by a defective function of regulatory T cells
(Tregs). The aim of this study is to establish the potential link
between these diseases and CD4+, CD25+ FoxP3+ Tregs as well as T
helper cells (Ths) in children. This is a prospective case control
study. Obese (n:40), asthmatic (n:40), asthmatic obese (n:40) and
healthy children (n:40), who don't have any acute or chronic diseases,
were included in this study. Obese children were evaluated according
to WHO criteria. Asthmatic patients were chosen based on GINA
criteria. Parents were asked to fill up the questionnaire. Informed
consent forms were taken. Blood samples were marked with CD4+,
CD25+ and FoxP3+ in order to determine Tregs and Ths by flow
cytometric method. Statistical analyses were performed. p≤0.05 was
chosen as meaningful threshold. Tregs exhibiting anti-inflammatory
nature were significantly lower in obese (0,16%; p≤0,001), asthmatic
(0,25%; p≤0,01) and asthmatic obese (0,29%; p≤0,05) groups than
the control group (0,38%). Ths were counted higher in asthma group
than the control (p≤0,01) and obese (p≤0,001) groups. T cell
immunity plays important roles in obesity and asthma pathogeneses.
Decreased numbers of Tregs found in obese, asthmatic and asthmatic
obese children may help to elucidate some questions in
pathophysiology of these diseases. For HOMA-IR levels, any
significant difference was not noted between control and obese
groups, but statistically higher values were found for obese
asthmatics. The values obtained in all groups were found to be below
the critical cut off points. This finding has made the statistically
significant difference observed between Tregs of obese, asthmatic,
obese asthmatic and control groups much more valuable. These
findings will be useful in diagnosis and treatment of these disorders
and future studies are needed. The production and propagation of
Tregs may be promising in alternative asthma and obesity treatments.
Abstract: In the current work, a three-dimensional geometry of a
75% stenosed blood vessel is analyzed. Large eddy simulation (LES)
with the help of a dynamic subgrid scale Smagorinsky model is
applied to model the turbulent pulsatile flow. The geometry, the
transmural pressure and the properties of the blood and the elastic
boundary were based on clinical measurement data. For the flexible
wall model, a thin solid region is constructed around the 75%
stenosed blood vessel. The deformation of this solid region was
modelled as a deforming boundary to reduce the computational cost
of the solid model. Fluid-structure interaction is realized via a twoway
coupling between the blood flow modelled via LES and the
deforming vessel. The information of the flow pressure and the wall
motion was exchanged continually during the cycle by an arbitrary
Lagrangian-Eulerian method. The boundary condition of current time
step depended on previous solutions. The fluctuation of the velocity
in the post-stenotic region was analyzed in the study. The axial
velocity at normalized position Z=0.5 shows a negative value near
the vessel wall. The displacement of the elastic boundary was
concerned in this study. In particular, the wall displacement at the
systole and the diastole were compared. The negative displacement at
the stenosis indicates a collapse at the maximum velocity and the
deceleration phase.
Abstract: Predicting the collapse potential of a structure during
earthquakes is an important issue in earthquake engineering. Many
researchers proposed different methods to assess the collapse
potential of structures under the effect of strong ground motions.
However most of them did not consider degradation and softening
effect in hysteretic behavior. In this study, collapse potential of
SDOF systems caused by dynamic instability with stiffness and
strength degradation has been investigated. An equation was
proposed for the estimation of collapse period of SDOF system which
is a limit value of period for dynamic instability. If period of the
considered SDOF system is shorter than the collapse period then the
relevant system exhibits dynamic instability and collapse occurs.
Abstract: Image segmentation plays an important role in
medical imaging applications. Therefore, accurate methods are
needed for the successful segmentation of medical images for
diagnosis and detection of various diseases. In this paper, we have
used maximum entropy to achieve image segmentation. Maximum
entropy has been calculated using Shannon, Renyi and Tsallis
entropies. This work has novelty based on the detection of skin lesion
caused by the bite of a parasite called Sand Fly causing the disease is
called Cutaneous Leishmaniasis.
Abstract: This exploratory study gives an overview of the
evolution of the main financial and performance indicators of the
Academic Spin-Off’s and High Growth Academic Spin-Off’s in year
3 and year 6 after its creation in the region of Catalonia in Spain. The
study compares and evaluates results of these different measures of
performance and the degree of success of these companies for each
University.
We found that the average Catalonian Academic Spin-Off is small
and have not achieved the sustainability stage at year 6. On the
contrary, a small group of High Growth Academic Spin-Off’s
exhibits robust performance with high profits in year 6. Our results
support the need to increase selectivity and support for these
companies especially near year 3, because are the ones that will bring
wealth and employment. University role as an investor has rigid
norms and habits that impede an efficient economic return from their
ASO investment.
Universities with high performance on sales and employment in
year 3 not always could sustain this growth in year 6 because their
ASO’s are not profitable. On the contrary, profitable ASO exhibit
superior performance in all measurement indicators in year 6. We
advocate the need of a balanced growth (with profits) as a way to
obtain subsequent continuous growth.
Abstract: Flash Floods, together with landslides, are a common
natural threat for people living in mountainous regions and foothills.
One way to deal with this constant menace is the use of Early
Warning Systems, which have become a very important mitigation
strategy for natural disasters.
In this work we present our proposal for a pilot Flash Flood Early
Warning System for Santiago, Chile, the first stage of a more
ambitious project that in a future stage shall also include early
warning of landslides.
To give a context for our approach, we first analyze three existing
Flash Flood Early Warning Systems, focusing on their general
architectures. We then present our proposed system, with main focus
on the decision support system, a system that integrates empirical
models and fuzzy expert systems to achieve reliable risk estimations.
Abstract: Using the first-principles full-potential linearized
augmented plane wave plus local orbital (FP-LAPW+lo) method
based on density functional theory (DFT), we have investigated the
electronic structure and magnetism of full Heusler alloys Co2ZrGe
and Co2NbB. These compounds are predicted to be half-metallic
ferromagnets (HMFs) with a total magnetic moment of 2.000 B per
formula unit, well consistent with the Slater-Pauling rule.
Calculations show that both the alloys have an indirect band gaps, in
the minority-spin channel of density of states (DOS), with values of
0.58 eV and 0.47 eV for Co2ZrGe and Co2NbB, respectively.
Analysis of the DOS and magnetic moments indicates that their
magnetism is mainly related to the d-d hybridization between the Co
and Zr (or Nb) atoms. The half-metallicity is found to be relatively
robust against volume changes. In addition, an atom inside molecule
AIM formalism and an electron localization function ELF were also
adopted to study the bonding properties of these compounds, building
a bridge between their electronic and bonding behavior.
As they have a good crystallographic compatibility with the lattice of
semiconductors used industrially and negative calculated cohesive
energies with considerable absolute values these two alloys could be
promising magnetic materials in the spintronic field.
Abstract: Morphological interaction of porcine cumulus-oocyte
complexes (pCOCs) was investigated on in vitro condition using
electron microscope (SEM and TEM). The totals of 1,923 oocytes
were round in shape, surrounded by Zona pellucida with layer of
cumulus cells ranging between 59.29-202.14 μm in size. They were
classified into intact-, multi-, partial cumulus cell layer oocyte, and
completely denuded oocyte, at the percentage composition of 22.80%
32.70%, 18.60%, and 25.90 % respectively. The pCOCs classified as
intact- and multi cumulus cell layer oocytes were further culturing at
37°C with 5% CO2, 95% air atmosphere and high humidity for 44 h
in M199 with Earle’s salts supplemented with 10% HTFCS, 2.2
mg/mL NaHCO3, 1 M Hepes, 0.25 mM pyruvate, 15 μg/mL porcine
follicle-stimulating hormone, 1 μg/mL LH, 1μg/mL estradiol with
ethanol, and 50 μg/mL gentamycin sulfate. On electron microscope
study, cumulus cells were found to stick their processes to secrete
substance from the sac-shape end into Zona pellucida of the oocyte
and also communicated with the neighboring cells through their
microvilli on the beginning of incubation period. It is believed that
the cumulus cells communicate with the oocyte by inserting the
microvilli through this gap and embedded in the oocyte cytoplasm
before secreting substance, through the sac-shape end of the
microvilli, to inhibit primary oocyte development at the prophase I.
Morphological changes of the complexes were observed after
culturing for 24-44 h. One hundred percentages of the cumulus layers
were expanded and cumulus cells were peeling off from the oocyte
surface. In addition, the round-shape cumulus cells transformed
themselves into either an elongate shape or a columnar shape, and no
communication between cumulus neighboring cells. After 44 h of
incubation time, diameter of oocytes surrounded by cumulus cells
was larger than 0 h incubation. The effect of hormones in culture
medium is exerted by their receptors present in porcine oocyte. It is
likely that all morphological changes of the complexes after hormone
treatment were to allow maturation of the oocyte. This study
demonstrated that the association of hormones in M199 could
promote porcine follicle activation in 44 h in vitro condition. This
culture system should be useful for studying the regulation of early
follicular growth and development, especially because these follicles represent a large source of oocytes that could be used in vitro for cell
technology.
Abstract: Beta-glucosidase, chitinase, leucine-aminopeptidase, acid phosphomonoesterase and acetate-esterase enzyme activities in
the soils under the impact of metallurgical industrial activity in Lori
marz (district) were investigated. The results of the study showed that
the activities of the investigated enzymes in the soils decreased with increasing distance from the Shamlugh copper mine, the Chochkan
tailings storage facility and the ore transportation road. Statistical
analysis revealed that the activities of the enzymes were positively
correlated (significant) to each other according to the observation
sites which indicated that enzyme activities were affected by the
same anthropogenic factor. The investigations showed that the soils
were polluted with heavy metals (Cu, Pb, As, Co, Ni, Zn) due to
copper mining activity in this territory. The results of Pearson
correlation analysis revealed a significant negative correlation
between heavy metal pollution degree (Nemerow integrated pollution
index) and soil enzyme activity. All of this indicated that copper
mining activity in this territory causing the heavy metal pollution of
the soils resulted in the inhabitation of the activities of the enzymes
which are considered as biological catalysts to decompose organic
materials and facilitate the cycling of nutrients.
Abstract: Interaction of Schiff base complexes of Iron and
Manganese: Iron [N, N’ Bis (5- (triphenyl phosphonium methyl)
salicylidene) -1, 2 ethanediamine) chloride, [Fe Salen]Cl; Manganese
[N, N’ Bis (5- (triphenyl phosphonium methyl) salicylidene) -1, 2
ethanediamine) acetate, were investigated by spectroscopic and
isothermal titration calorimetry techniques (ITC).
The absorbance spectra of complexes have shown hyper and
hypochromism in the presence of DNA that is indication of
interaction of complexes with DNA. The linear dichroism (LD)
measurements confirmed the bending of DNA in the presence of
complexes.
Furthermore, Isothermal titration calorimetry experiments
approved that complexes bound to DNA on the base of both
electrostatic and hydrophobic interactions. More, ITC profile exhibits
the existence of two binding phases for the complexes. Antibacterial
activity of ligand and complexes were tested in vitro to evaluate their
activity against the gram positive and negative bacteria.
Abstract: The Algeria by its location offers a rich and diverse
vegetation. A large number of aromatic and medicinal plants grow
spontaneously. The interest in these plants has continued to grow in
recent years. Their particular properties due to the essential oil
fraction can be utilized to treat microbial infections. To this end, and
in the context of the valuation of the Algerian flora, we became
interested in the species of the family Lamiaceae which is one of the
most used as a global source of spices. The plant on which we have
based our choice is a species of sage "Salvia officinalis" from the
Isser localized region within the province of Boumerdes. This work
focuses on the study of the antimicrobial activity of essential oil
extracted from the leaves of Salvia officinalis. The extraction is
carried out by essential oil hydrodistillation and reveals a yield of
1.06℅. The study of the antimicrobial activity of the essential oil by
the method of at aromatogramme shown that Gram positive bacteria
are most susceptible (Staphylococcus aureus and Bacillus subtilis)
with a strong inhibition of growth. The yeast Candida albicans
fungus Aspergillus niger and have shown moderately sensitive.
Abstract: Array-based gene expression analysis is a powerful
tool to profile expression of genes and to generate information on
therapeutic effects of new anti-cancer compounds. Anti-apoptotic
effect of thymoquinone was studied in MCF7 breast cancer cell line
using gene expression profiling with cDNA microarray. The purity
and yield of RNA samples were determined using RNeasyPlus Mini
kit. The Agilent RNA 6000 NanoLabChip kit evaluated the quantity
of the RNA samples. AffinityScript RT oligo-dT promoter primer
was used to generate cDNA strands. T7 RNA polymerase was used to
convert cDNA to cRNA. The cRNA samples and human universal
reference RNA were labelled with Cy-3-CTP and Cy-5-CTP,
respectively. Feature Extraction and GeneSpring softwares analysed
the data. The single experiment analysis revealed involvement of 64
pathways with up-regulated genes and 78 pathways with downregulated
genes. The MAPK and p38-MAPK pathways were
inhibited due to the up-regulation of PTPRR gene. The inhibition of
p38-MAPK suggested up-regulation of TGF-ß pathway. Inhibition of
p38-MAPK caused up-regulation of TP53 and down-regulation of
Bcl2 genes indicating involvement of intrinsic apoptotic pathway.
Down-regulation of CARD16 gene as an adaptor molecule regulated
CASP1 and suggested necrosis-like programmed cell death and
involvement of caspase in apoptosis. Furthermore, down-regulation
of GPCR, EGF-EGFR signalling pathways suggested reduction of
ER. Involvement of AhR pathway which control cytochrome P450
and glucuronidation pathways showed metabolism of Thymoquinone.
The findings showed differential expression of several genes in
apoptosis pathways with thymoquinone treatment in estrogen
receptor-positive breast cancer cells.
Abstract: Hybrid bioreactor having both suspended-growth and
attached-growth bacteria is found a novel and excellent bioreactor
system for treating the municipal wastewater containing inhibitory
substrates too. In this reactor a fraction of substrate is used by
suspended biomass and the remaining by attached biomass resulting
in the competition between the two growths for the substrate. The
combination of suspended and attached growth provides the system
with enhanced biomass concentration and sludge age more than those
in ASP. Similar to attached growth system, the hybrid bioreactor
ensures considerable efficiency for treating toxic and refractory
substances in wastewater. For the process design of hybrid bioreactor
a suitable mathematical model is required. Although various
mathematical models were developed on hybrid bioreactor in due
course of time in earlier research works, none of them was found
having a specific simplified solution of the corresponding models and
without having any drawback. To overcome this drawback authors
already developed a simplified mathematical model for process
design of a hybrid bioreactor. The present paper briefly highlights on
the various aspects of process design of an aerobic hybrid bioreactor
for the treatment of municipal wastewater.
Abstract: Bir El Djir is an important coastal township in Oran
department, located at 450 Km far away from Algiers on northwest of
Algeria. In this coastal area, the urban sprawl is one of the main
problems that reduce the limited highly fertile land. So, using the
remote sensing and GIS technologies have shown their great
capabilities to solve many earth resources issues.
The aim of this study is to produce land use and cover map for the
studied area at varied periods to monitor possible changes that may
occurred, particularly in the urban areas and subsequently predict
likely changes. For this, two spatial images SPOT and Landsat
satellites from 1987 and 2014 respectively were used to assess the
changes of urban expansion and encroachment during this period
with photo-interpretation and GIS approach.
The results revealed that the town of Bir El Djir has shown a
highest growth rate in the period 1987-2014 which is 1201.5 hectares
in terms of area. These expansions largely concern the new real estate
constructions falling within the social and promotional housing
programs launched by the government.
The most urban expansion is characterized by the new
construction in the form of spontaneous or peripheral precarious
habitat, but also unstructured slums settled especially in the
southeastern part of town.
Abstract: One of the best examples, in evolution of the public
procurement, from post-soviet countries are reforms carried out in
Georgia, which brought them close to international standards of
procurement. In Georgia, public procurement legislation started
functioning short after gaining independence. The reform has passed
several stages and came in the form as it is today. It should also be
noted, that countries with economy in transition, including Georgia,
implemented all the reforms in public procurement based on
recommendations and support of World Bank, the United Nations
and other international organizations.
The aim of first adopted law was regulation of the procurement
process of budget-organizations, transparency and creation of
competitive environment for private companies to access state funds
legally. The priorities were identified quite clearly in the wording of
the law, but operation/function of this law could not be reached on its
level, because of some objective and subjective reasons. The high
level of corruption in all levels of governance can be considered as a
main obstacle reason and of course, it is natural, that it had direct
impact on the procurement process, as well as on transparency and
rational use of state funds. These circumstances were the reasons that
reforms in this sphere continued, to improve procurement process, in
particular, the first wave of reforms began after several years. Public
procurement agency carried out reform with World Bank with main
purpose of smartening the procurement legislation and its
harmonization with international treaties and agreements. Also with
the support of World Bank various activities were carried out to raise
awareness of participants involved in procurement system.
Further major changes in the legislation were filed bit later, which
was also directed towards the improvement and smarten of the
procurement process. The third wave of the reform more or less
guaranteed the transparency of the procurement process, which later
became the basis for the rational spending of state funds. The reform
of the procurement system completely changed the procedures.
Carried out reform in Georgia resulted in introducing new
electronic tendering system, which benefit the transparency of the
process, after this became the basis for the further development of a
competitive environment, which become a prerequisite for the state
rational spending. Increased number of supplier organizations
participating in the procurement process resulted in reduction of the
estimated cost and the actual cost.
Assessment of the reforms in Georgia in the field of public
procurement can be concluded, that proper regulation of the sector
and relevant policy may proceed to rational and transparent spending
of the budget from country’s state institutions. Also, the business
sector has the opportunity to work in competitive market conditions
and to make a preliminary analysis, which is a prerequisite for future
strategy and development.
Abstract: Enterococci are important inhabitants of the animal
intestine and are widely used in probiotic products. A probiotic strain
is expected to possess several desirable properties in order to exert
beneficial effects. Therefore, the objective of this study was to
isolate, characterize and identify Enterococcus sp. from chicken cecal
and fecal samples to determine potential probiotic properties.
Enterococci were isolated from chicken ceca and feces of thirty three
clinically healthy chickens from a local farm. In vitro studies were
performed to assess antibacterial activity of the isolated LAB (using
agar well diffusion and cell free supernatant broth technique against
Salmonella enterica serotype Enteritidis), survival in acidic
conditions, resistance to bile salts, and their survival during simulated
gastric juice conditions at pH 2.5. Isolates were identified by
biochemical carbohydrate fermentation patterns using an API 50
CHL kit and API ZYM kits and by sequenced 16S rDNA. An isolate
belonging to E. faecium species exhibited inhibitory effect against S.
enteritidis. This isolate producing a clear zone as large as 10.30 mm
or greater and was able to grow in the coculture medium and at the
same time, inhibited the growth S. enteritidis. In addition, E. faecium
exhibited significant resistance under highly acidic conditions at pH
2.5 for 8 h and survived well in bile salt at 0.2% for 24 h and showing
ability to survive in the presence of simulated gastric juice at pH 2.5.
Based on these results, E. faecium isolate fulfills some of the criteria
to be considered as a probiotic strain and therefore, could be used as a
feed additive with good potential for controlling S. Enteritidis in
chickens. However, in vivo studies are needed to determine the safety
of the strain.
Abstract: Robotic surgery is used to enhance minimally invasive
surgical procedure. It provides greater degree of freedom for surgical
tools but lacks of haptic feedback system to provide sense of touch to
the surgeon. Surgical robots work on master-slave operation, where
user is a master and robotic arms are the slaves. Current, surgical
robots provide precise control of the surgical tools, but heavily rely
on visual feedback, which sometimes cause damage to the inner
organs. The goal of this research was to design and develop a realtime
Simulink based robotic system to study force feedback
mechanism during instrument-object interaction. Setup includes three
VelmexXSlide assembly (XYZ Stage) for three dimensional
movement, an end effector assembly for forceps, electronic circuit for
four strain gages, two Novint Falcon 3D gaming controllers,
microcontroller board with linear actuators, MATLAB and Simulink
toolboxes. Strain gages were calibrated using Imada Digital Force
Gauge device and tested with a hard-core wire to measure
instrument-object interaction in the range of 0-35N. Designed
Simulink model successfully acquires 3D coordinates from two
Novint Falcon controllers and transfer coordinates to the XYZ stage
and forceps. Simulink model also reads strain gages signal through
10-bit analog to digital converter resolution of a microcontroller
assembly in real time, converts voltage into force and feedback the
output signals to the Novint Falcon controller for force feedback
mechanism. Experimental setup allows user to change forward
kinematics algorithms to achieve the best-desired movement of the
XYZ stage and forceps. This project combines haptic technology
with surgical robot to provide sense of touch to the user controlling
forceps through machine-computer interface.