Abstract: It is the patient compliance and stability in
combination with controlled drug delivery and biocompatibility that
forms the core feature in present research and development of
sustained biodegradable patch formulation intended for wound
healing. The aim was to impart sustained degradation, sterile
formulation, significant folding endurance, elasticity,
biodegradability, bio-acceptability and strength. The optimized
formulation comprised of polymers including Hydroxypropyl methyl
cellulose, Ethylcellulose, and Gelatin, and Citric Acid PEG Citric
acid (CPEGC) triblock dendrimers and active Curcumin. Polymeric
mixture dissolved in geometric order in suitable medium through
continuous stirring under ambient conditions. With continued stirring
Curcumin was added with aid of DCM and Methanol in optimized
ratio to get homogenous dispersion. The dispersion was sonicated
with optimum frequency and for given time and later casted to form a
patch form. All steps were carried out under strict aseptic conditions.
The formulations obtained in the acceptable working range were
decided based on thickness, uniformity of drug content, smooth
texture and flexibility and brittleness. The patch kept on stability
using butter paper in sterile pack displayed folding endurance in
range of 20 to 23 times without any evidence of crack in an
optimized formulation at room temperature (RT) (24 ± 2°C). The
patch displayed acceptable parameters after stability study conducted
in refrigerated conditions (8±0.2°C) and at RT (24 ± 2°C) up to 90
days. Further, no significant changes were observed in critical
parameters such as elasticity, biodegradability, drug release and drug
content during stability study conducted at RT 24±2°C for 45 and 90
days. The drug content was in range 95 to 102%, moisture content
didn’t exceeded 19.2% and patch passed the content uniformity test.
Percentage cumulative drug release was found to be 80% in 12h and
matched the biodegradation rate as drug release with correlation
factor R2>0.9. The biodegradable patch based formulation developed
shows promising results in terms of stability and release profiles.
Abstract: Electrostatic interaction energy (ΔEEDL) is a part of the Extended Derjaguin-Landau-Verwey-Overbeek (XDLVO) theory, which, together with van der Waals (ΔEVDW) and acid base (ΔEAB) interaction energies, has been extensively used to investigate the initial adhesion of bacteria to surfaces. Electrostatic or electrical double layer interaction energy is considerably affected by surface potential; however it cannot be determined experimentally and is usually replaced by zeta (ζ) potential via electrophoretic mobility. This paper focusses on the effect of ionic concentration as a function of pH and the effect of mineral grain size on ζ potential. It was found that both ionic strength and mineral grain size play a major role in determining the value of ζ potential for the adhesion of P. putida to hematite and quartz surfaces. Higher ζ potential values lead to higher electrostatic interaction energies and eventually to higher total XDLVO interaction energy resulting in bacterial repulsion.
Abstract: Passive control methods can be utilized to build
earthquake resistant structures, and also to strengthen the vulnerable
ones. In this paper, we studied the effect of this system in increasing
the ductility and energy dissipation and also modeled the behavior of
this type of eccentric bracing, and compared the hysteresis diagram
of the modeled samples with the laboratory samples. We studied
several samples of frames with vertical shear-links in order to assess
the behavior of this type of eccentric bracing. Each of these samples
was modeled in finite element software ANSYS 9.0, and was
analyzed under the static cyclic loading. It was found that vertical
shear-links have a more stable hysteresis loops. Another analysis
showed that using honeycomb beams as the horizontal beam along
with steel reinforcement has no negative effect on the hysteresis
behavior of the sample.
Abstract: In this paper, relationship between different properties
of IC concrete and water cement ratio, obtained from a
comprehensive experiment conducted on IC using local materials
(Burnt clay chips- BC) is presented. In addition, saturated SAP was
used as an IC material in some cases. Relationships have been
developed through regression analysis. The focus of this analysis is
on developing relationship between a dependent variable and an
independent variable. Different percent replacements of BC and
water cement ratios were used. Compressive strength, modulus of
elasticity, water permeability and chloride permeability were tested
and variations of these parameters were analyzed with respect to
water cement ratio.
Abstract: Concrete is strong in compression however weak in
tension. The tensile strength as well as ductile property of concrete
could be improved by addition of short dispersed fibers. Polyethylene
terephthalate (PET) fiber obtained from hand cutting or mechanical
slitting of plastic sheets generally used as discrete reinforcement in
substitution of steel fiber. PET fiber obtained from the former process
is in the form of straight slit sheet pattern that impart weaker
mechanical bonding behavior in the concrete matrix. To improve the
limitation of straight slit sheet fiber the present study considered two
additional geometry of fiber namely (a) flattened end slit sheet and
(b) deformed slit sheet. The mix for plain concrete was design for a
compressive strength of 25 MPa at 28 days curing time with a watercement
ratio of 0.5. Cylindrical and beam specimens with 0.5% fibers
volume fraction and without fibers were cast to investigate the
influence of geometry on the mechanical properties of concrete. The
performance parameters mainly studied include flexural strength,
splitting tensile strength, compressive strength and ultrasonic pulse
velocity (UPV). Test results show that geometry of fiber has a
marginal effect on the workability of concrete. However, it plays a
significant role in achieving a good compressive and tensile strength
of concrete. Further, significant improvement in term of flexural and
energy dissipation capacity were observed from other fibers as
compared to the straight slit sheet pattern. Also, the inclusion of PET
fiber improved the ability in absorbing energy in the post-cracking
state of the specimen as well as no significant porous structures.
Abstract: The goal of the modern education system is to prepare
students to be able to adapt to ever-changing life situations. They
must be able to acquire required knowledge independently; apply
such knowledge in practice to solve various problems by using
modern technologies; think critically and creatively; competently use
information; be communicative, work in a team; and develop their
own moral values, intellect and cultural awareness. As a result, the
status of education significantly increases; new requirements to its
quality have been formed. In recent years the competency-based
approach in education has become of significant interest. This
approach is a strengthening of applied and practical characteristics of
a school education and leads to the forming of the key students’
competencies which define their success in future life. In this article,
the authors’ attention focuses on a range of key competencies,
educational, informational and communicative and on the possibility
to develop such competencies via STEM education. This research
shows the change in students’ attitude towards scientific disciplines
such as mathematics, general science, technology and engineering as
a result of STEM education. Two staged analyzed questionnaires
completed by students of forms II to IV in the republic of Trinidad
and Tobago allowed the authors to categorize students between two
levels that represent students’ attitude to various disciplines. The
significance of differences between selected levels was confirmed
with the use of Pearson’s chi-squared test. In summary, the analysis
of obtained data makes it possible to conclude that STEM education
has a great potential for development of core students’ competencies
and encourage the development of positive student attitude towards
the above mentioned above scientific disciplines.
Abstract: This paper seeks to assess the implications of
insurance to foreign direct investment inflow in Nigeria. Multiple
linear regression technique and correlation matrix test were employed
to measure the extent to which foreign direct investment was
influenced. The result showed that insurance premium (IP), asset size
of insurance industry (AS), and total investment of the industry (TI)
impacted significantly and positively on foreign direct investment
inflow in Nigeria. There should be effective risk transfer mechanism
and financial intermediation, which gives the investor confidence in
the risk management strength of the host country.
Abstract: Twin steel plates-concrete composite shear walls are
composed of a pair of steel plate layers and a concrete layer
sandwiched between them, which have the characteristics of both
reinforced concrete shear walls and steel plate shear walls. Twin steel
plates-composite shear walls contain very high ultimsate bearing
capacity and ductility, which have great potential to be applied in the
super high-rise buildings and special structures. In this paper, we
analyzed the basic characteristics and stress mechanism of the twin
steel plates-composite shear walls. Specifically, we analyzed the
effects of the steel plate thickness, wall thickness and concrete
strength on the bearing capacity of the twin steel plates-composite
shear walls. The analysis results indicate that: (1) the initial shear
stiffness and ultimate shear-carrying capacity is not significantly
affected by the thickness of concrete wall but by the class of concrete,
(2) both factors significantly impact the shear distribution of the
shear walls in ultimate shear-carrying capacity. The technique of twin
steel plates-composite shear walls has been successfully applied in
the construction of an 88-meter Huge Statue of Buddha located in
Hunan Province, China. The analysis results and engineering
experiences showed that the twin steel plates-composite shear walls
have great potential for future research and applications.
Abstract: This research paper presents the current practices of
teacher professional development, perceived as beneficial by teachers
themselves, in a private secondary school in Brunei Darussalam. This
is part of the findings of a larger qualitative study on teacher
empowerment, using ethnographic methods for data collection, i.e.
participant observation, interviews and document analysis. The field
work was carried out over a period of six months in 2013. An
analysis of the field data revealed multiple pathways of teacher
professional development existing in the school. The results indicate
that school leaders, the teacher community in the school, students,
and the teachers themselves were the agents in a school that
facilitated teacher empowerment. Besides contributing to the
knowledge base on teacher professional development, the results of
this study provide directions for educational policy makers in their
efforts to enhance professional development in secondary schools of
similar characteristics. For school leaders and the teacher community,
these findings offer guidelines for maximizing the opportunities for
these professional development practices, by strengthening
collegiality and by using the existing structures optimally for the
benefit of all concerned.
Abstract: In recent years, the use of the aluminum based alloys
in the industry and technology are increasing. Alloying elements in
aluminum have further been improving the strength and stiffness
properties that provide superior compared to other metals. In this
study, investigation of physical properties (microstructure,
microhardness, tensile strength, electrical conductivity and thermal
properties) in the Al-12.6wt.%Si-%2wt.Ni ternary alloy were
investigated. Al-Si-Ni alloy was prepared in vacuum atmosphere. The
samples were directionally solidified upwards with different growth
rate V (8.3−165.45 μm/s) at constant temperature gradient G (7.73
K/mm). The flake spacings (λ), microhardness (HV), ultimate tensile
strength (σ), electrical resistivity (ρ) and thermal properties (H, Cp,
Tm) of the samples were measured. Influence of the growth rate and
spacings on microhardness, ultimate tensile strength and electrical
resistivity were investigated and relationships between them were
obtained. According to results, λ values decrease with increasing V,
but HV, σ and ρ values increase with increasing V. Variations of
electrical resistivity (ρ) of solidified samples were also measured.
The enthalpy of fusion (H) and specific heat (Cp) for the alloy was
also determined by differential scanning calorimeter (DSC) from
heating trace during the transformation from liquid to solid. The
results in this work were compared with the previous similar
experimental results.
Abstract: The localization information is crucial for the
operation of WSN. There are principally two types of localization
algorithms. The Range-based localization algorithm has strict
requirements on hardware, thus is expensive to be implemented in
practice. The Range-free localization algorithm reduces the hardware
cost. However, it can only achieve high accuracy in ideal scenarios.
In this paper, we locate unknown nodes by incorporating the
advantages of these two types of methods. The proposed algorithm
makes the unknown nodes select the nearest anchor using the
Received Signal Strength Indicator (RSSI) and choose two other
anchors which are the most accurate to achieve the estimated
location. Our algorithm improves the localization accuracy compared
with previous algorithms, which has been demonstrated by the
simulating results.
Abstract: Expansive soils are often encountered in many parts
of the world, especially in arid and semi-arid fields. Such kind of
soils, generally including active clay minerals in low water content,
enlarge in volume by absorbing the water through the surface and
cause a great harm to the light structures such as channel coating,
roads and airports. The expansive soils were encountered on the path
of Apa-Hotamış conveyance channel belonging to the State
Hydraulic Works in the region of Konya. In the research done in this
area, it is predicted that the soil has a swollen nature and the soil
should be filled with proper granular equipments by digging the
ground to 50-60 cm. In this study, for purpose of helping the other
research to be done in the same area, it is thought that instead of
replacing swollen soil with the granular soil, by stabilizing it with
polypropylene fiber and using it its original place decreases effect of
swelling percent, in this way the cost will be decreased. Therefore,
laboratory tests were conducted to study the effects of polypropylene
fiber on swelling characteristics of expansive soil. Test results
indicated that inclusion of fiber reduced swell percent of expansive
soil. As the fiber content increased, the unconfined compressive
strength was increased. Finally, it can be said that stabilization of
expansive soils with polypropylene fiber is an effective method.
Abstract: In this work, the plastic behaviour of cold-rolled zinc
coated dual-phase steel sheets DP600 and DP800 grades is firstly
investigated with the help of uniaxial, hydraulic bulge and Forming
Limit Curve (FLC) tests. The uniaxial tensile tests were performed in
three angular orientations with respect to the rolling direction to
evaluate the strain-hardening and plastic anisotropy. True stressstrain
curves at large strains were determined from hydraulic bulge
testing and fitted to a work-hardening equation. The limit strains are
defined at both localized necking and fracture conditions according to
Nakajima’s hemispherical punch procedure. Also, an elasto-plastic
localization model is proposed in order to predict strain and stress
based forming limit curves. The investigated dual-phase sheets
showed a good formability in the biaxial stretching and drawing FLC
regions. For both DP600 and DP800 sheets, the corresponding
numerical predictions overestimated and underestimated the
experimental limit strains in the biaxial stretching and drawing FLC
regions, respectively. This can be attributed to the restricted failure
necking condition adopted in the numerical model, which is not
suitable to describe the tensile and shear fracture mechanisms in
advanced high strength steels under equibiaxial and biaxial stretching
conditions.
Abstract: This paper develops and investigates a framework for
the assessment of customer involvement in the service design process
of result oriented product-service systems in order to improve the
service offering in a business-to-business (B2B) context. The
framework comprises five main criteria and fifteen sub-criteria that
contribute to customer involvement in a hierarchy using a maturity
grid to highlight the strengths and weaknesses for each criterion. To
develop the customer involvement framework, an extensive literature
review related to service design, result oriented product-service
system (PSS) and customer involvement in service design was
carried out. Key factors that significantly influence customer
involvement from industry and literature were identified to develop
the framework. A major contribution of the developed framework
includes a hierarchy of appropriate criteria for assessing customer
involvement in the service design process within results oriented
PSS; the definition of four maturity levels which are suitable to
describe the whole spectrum of customer involvement in the service
design process; and finally, The paper concludes by enabling service
providers to: take proactive decisions; screen and evaluate new
services; improve perceived service quality; and provide barriers
against imitation.
Abstract: Public space is essential to strengthen the social and
urban fabric and the social cohesion; there lies the importance of its
study. Hence, the aim of this paper is to analyze the quality of public
space in the XXI century in both quantitative and qualitative terms. In
this article, the concept of public space includes open spaces such as
parks, public squares and walking areas. To make this analysis, we
take Mexico City as the case study. It has a population of nearly 9
million inhabitants and is composed of sixteen boroughs. For this
analysis, we consider both existing public spaces and the government
intervention for building and improving new and existent public
spaces. Results show that on the one hand, quantitatively there is not
an equitable distribution of public spaces due to both the growth of
the city itself as well as due to the absence of political will to create
public spaces. Another factor is the evolution of this city, which has
been growing merely in a “patched pattern”, where public space has
played no role at all with a total absence of urban design. On the
other hand, qualitatively, even the boroughs with the most public
spaces have not shown interest in making these spaces qualitatively
inclusive and open to the general population aiming for integration.
Therefore, urban projects that privatize public space seem to be the
rule, rather than a rehabilitation effort of the existent public spaces.
Hence, state intervention should reinforce its role as an agent of
social change acting in benefit of the majority of the inhabitants with
the promotion of more inclusive public spaces.
Abstract: This study analyzes the critical gaps in the
architecture of European stability and the expected role of the
banking union as the new important step towards completing the
Economic and Monetary Union that should enable the creation of
safe and sound financial sector for the euro area market. The single
rulebook together with the Single Supervisory Mechanism and the
Single Resolution Mechanism - as two main pillars of the banking
union, should provide a consistent application of common rules and
administrative standards for supervision, recovery and resolution of
banks – with the final aim of replacing the former bail-out practice
with the bail-in system through which possible future bank failures
would be resolved by their own funds, i.e. with minimal costs for
taxpayers and real economy. In this way, the vicious circle between
banks and sovereigns would be broken. It would also reduce the
financial fragmentation recorded in the years of crisis as the result of
divergent behaviors in risk premium, lending activities and interest
rates between the core and the periphery. In addition, it should
strengthen the effectiveness of monetary transmission channels, in
particular the credit channels and overflows of liquidity on the money
market which, due to the fragmentation of the common financial
market, has been significantly disabled in period of crisis. However,
contrary to all the positive expectations related to the future
functioning of the banking union, major findings of this study
indicate that characteristics of the economic system in which the
banking union will operate should not be ignored. The euro area is an
integration of strong and weak entities with large differences in
economic development, wealth, assets of banking systems, growth
rates and accountability of fiscal policy. The analysis indicates that
low and unbalanced economic growth remains a challenge for the
maintenance of financial stability and this problem cannot be
resolved just by a single supervision. In many countries bank assets
exceed their GDP by several times and large banks are still a matter
of concern, because of their systemic importance for individual
countries and the euro zone as a whole. The creation of the Single
Supervisory Mechanism and the Single Resolution Mechanism is a
response to the European crisis, which has particularly affected
peripheral countries and caused the associated loop between the
banking crisis and the sovereign debt crisis, but has also influenced
banks’ balance sheets in the core countries, as the result of crossborder
capital flows. The creation of the SSM and the SRM should
prevent the similar episodes to happen again and should also provide
a new opportunity for strengthening of economic and financial
systems of the peripheral countries. On the other hand, there is a
potential threat that future focus of the ECB, resolution mechanism
and other relevant institutions will be extremely oriented towards
large and significant banks (whereby one half of them operate in the
core and most important euro area countries), and therefore it remains
questionable to what extent will the common resolution funds will be used for rescue of less important institutions. Recent geopolitical
developments will be the optimal indicator to show whether the
previously established mechanisms are sufficient enough to maintain
the adequate financial stability in the euro area market.
Abstract: In the present study, the properties of Al-Al2O3
nanocomposite hollow sphere structures were investigated. For this
reason, the Al-based nanocomposite hollow spheres with different
amounts of nano-alumina reinforcement (0-10wt %) and different
ratio of thickness to diameter (t/D: 0.06-0.3) were prepared via a
powder metallurgy method. Then, the effect of mentioned parameters
was studied on physical and quasi static mechanical properties of
their related prepared structures (open/closed cell) such as density,
hardness, strength, and energy absorption. It was found that, as the
t/D ratio increases the relative density, compressive strength and
energy absorption increase. The highest values of strength and energy
absorption were obtained from the specimen with 5 wt. % of
nanoparticle reinforcement, t/D of 0.3 (t=1 mm, D=400μm) as 22.88
MPa and 13.24 MJ/m3, respectively. The moderate specific strength
of prepared composites in the present study showed the good
consistency with the properties of others low carbon steel composite
with similar structure.
Abstract: Sustainability is a very important and heavily
discussed subject, expanding through tourism as well. The study
proposition was to collect data and present it to the competent bodies
so they can mold their public policies to improve the conditions of
the site. It was hypothesized that the lack of data is currently
affecting the quality of life and the sustainable development of the
site and the tourism. The research was held in Mateiros, a city in the
state of Tocantins (TO)/Brasil near Palmas, its capital city. Because
of the concentration of tourists during the high season and several
tourist attractions being around, the research took place in Mateiros.
The methodological procedure had a script of theoretical construction
and investigation of the deductive scientific method parameters
through a case study in the Jalapão/TO/Brazil region, using it as a
tool for a questionnaire given to the competent bodies in an interview
system with the UN sustainability indexes as a base. In the three
sustainable development scope: environmental, social and economic,
the results indicated that the data presented by the interviewed were
scarce or nonexistent. It shows that more research is necessary,
providing the tools for the ones responsible to propose action plans to
improve the site, strengthening the tourism and making it even more
sustainable.
Abstract: Ceramic Waste Aggregates (CWAs) were made from
electric porcelain insulator wastes supplied from an electric power
company, which were crushed and ground to fine aggregate sizes. In
this study, to develop the CWA mortar as an eco–efficient, ground
granulated blast–furnace slag (GGBS) as a Supplementary
Cementitious Material (SCM) was incorporated. The water–to–binder
ratio (W/B) of the CWA mortars was varied at 0.4, 0.5, and 0.6. The
cement of the CWA mortar was replaced by GGBS at 20 and 40% by
volume (at about 18 and 37% by weight). Mechanical properties of
compressive and splitting tensile strengths, and elastic modulus were
evaluated at the age of 7, 28, and 91 days. Moreover, the chloride
ingress test was carried out on the CWA mortars in a 5.0% NaCl
solution for 48 weeks. The chloride diffusion was assessed by using an
electron probe microanalysis (EPMA). To consider the relation of the
apparent chloride diffusion coefficient and the pore size, the pore size
distribution test was also performed using a mercury intrusion
porosimetry at the same time with the EPMA. The compressive
strength of the CWA mortars with the GGBS was higher than that
without the GGBS at the age of 28 and 91 days. The resistance to the
chloride ingress of the CWA mortar was effective in proportion to the
GGBS replacement level.
Abstract: In recent years, fire accidents have been steadily
increased and the amount of property damage caused by the accidents
has gradually raised. Damaging building structure, fire incidents bring
about not only such property damage but also strength degradation and
member deformation. As a result, the building structure undermines its
structural ability. Examining the degradation and the deformation is
very important because reusing the building is more economical than
reconstruction. Therefore, engineers need to investigate the strength
degradation and member deformation well, and make sure that they
apply right rehabilitation methods. This study aims at evaluating
deformation characteristics of fire damaged and rehabilitated normal
strength concrete beams through both experiments and finite element
analyses. For the experiments, control beams, fire damaged beams and
rehabilitated beams are tested to examine deformation characteristics.
Ten test beam specimens with compressive strength of 21MPa are
fabricated and main test variables are selected as cover thickness of
40mm and 50mm and fire exposure time of 1 hour or 2 hours. After
heating, fire damaged beams are air-recurred for 2 months and
rehabilitated beams are repaired with polymeric cement mortar after
being removed the fire damaged concrete cover. All beam specimens
are tested under four points loading. FE analyses are executed to
investigate the effects of main parameters applied to experimental
study. Test results show that both maximum load and stiffness of the
rehabilitated beams are higher than those of the fire damaged beams.
In addition, predicted structural behaviors from the analyses also show
good rehabilitation effect and the predicted load-deflection curves are
similar to the experimental results. For the further, the proposed
analytical method can be used to predict deformation characteristics of
fire damaged and rehabilitated concrete beams without suffering from
time and cost consuming of experimental process.