Scholarly

Is Curcumine Effect Comparable to 5- Aminosalicylic Acid or Budesonide on a Rat Model of Ulcerative Colitis Induced by Trinitrobenzene Sulfonic Acid?

Year: 2013 Volume: 7 Issue: 8 504 - 512 Pages

Abstract: Inflammatory bowel disease (IBD) is a chronic relapsing-remitting condition that afflicts millions of people throughout the world and impairs their daily functions and quality of life. Treatment of IBD depends largely on 5-aminosalicylic acid (5- ASA) and corticosteroids. The present study aimed to clarify the effects of 5-aminosalicylic acid, budesonide and currcumin on 90 male albino rats against trinitrobenzene sulfonic acid (TNB) induced colitis. TNB was injected intrarectally to 50 rats. The other 40 rats served as control groups. Both 5-ASA (in a dose of 120 mg/kg) and budesonide (in a dose of 0.1 mg/kg) were administered daily for one week whereas currcumin was injected intraperitonially (in a dose of 30 mg/kg daily) for 14 days after injection of either TNB in the colitis rats (group B) or saline in control groups (group A). The study included estimation of macroscopic score index, histological examination of H&E stained sections of the colonic tissue, biochemical estimation of myeloperoxidase (MPO), nitric oxide (NO), and caspase-3 levels, in addition to studying the effect of tested drugs on colonic motility. It was found that budesonide and curcumin improved mucosal healing, reduced both NO production and caspase- 3 level. They had the best impact on the disturbed colonic motility in TNBS-model of colitis.

Physicochemical Properties of Microemulsions and their uses in Enhanced Oil Recovery

Year: 2012 Volume: 6 Issue: 4 389 - 394 Pages

Abstract: Use of microemulsion in enhanced oil recovery has become more attractive in recent years because of its high level of extraction efficiency. Experimental investigations have been made on characterization of microemulsions of oil-brinesurfactant/ cosurfactant system for its use in enhanced oil recovery (EOR). Sodium dodecyl sulfate, propan-1-ol and heptane were selected as surfactant, cosurfactant and oil respectively for preparation of microemulsion. The effects of salinity on the relative phase volumes and solubilization parameters have also been studied. As salinity changes from low to high value, phase transition takes place from Winsor I to Winsor II via Winsor III. Suitable microemulsion composition has been selected based on its stability and ability to reduce interfacial tension. A series of flooding experiments have been performed using the selected microemulsion. The flooding experiments were performed in a core flooding apparatus using uniform sand pack. The core holder was tightly packed with uniform sands (60-100 mesh) and saturated with brines of different salinities. It was flooded with the brine at 25 psig and the absolute permeability was calculated from the flow rate of the through sand pack. The sand pack was then flooded with the crude oil at 800 psig to irreducible water saturation. The initial water saturation was determined on the basis of mass balance. Waterflooding was conducted by placing the coreholder horizontally at a constant injection pressure at 200 pisg. After water flooding, when water-cut reached above 95%, around 0.5 pore volume (PV) of the above microemulsion slug was injected followed by chasing water. The experiments were repeated using different composition of microemulsion slug. The additional recoveries were calculated by material balance. Encouraging results with additional recovery more than 20% of original oil in place above the conventional water flooding have been observed.

JConqurr - A Multi-Core Programming Toolkit for Java

Year: 2009 Volume: 3 Issue: 7 1857 - 1864 Pages

Abstract: With the popularity of the multi-core and many-core architectures there is a great requirement for software frameworks which can support parallel programming methodologies. In this paper we introduce an Eclipse toolkit, JConqurr which is easy to use and provides robust support for flexible parallel progrmaming. JConqurr is a multi-core and many-core programming toolkit for Java which is capable of providing support for common parallel programming patterns which include task, data, divide and conquer and pipeline parallelism. The toolkit uses an annotation and a directive mechanism to convert the sequential code into parallel code. In addition to that we have proposed a novel mechanism to achieve the parallelism using graphical processing units (GPU). Experiments with common parallelizable algorithms have shown that our toolkit can be easily and efficiently used to convert sequential code to parallel code and significant performance gains can be achieved.

Chikungunya Protease Domain–High Throughput Virtual Screening

Year: 2012 Volume: 6 Issue: 12 724 - 733 Pages

Abstract: Chikungunya virus (CHICKV) is an arboviruses belonging to family Tagoviridae and is transmitted to human through by mosquito (Aedes aegypti and Aedes albopictus) bite. A large outbreak of chikungunya has been reported in India between 2006 and 2007, along with several other countries from South-East Asia and for the first time in Europe. It was for the first time that the CHICKV outbreak has been reported with mortality from Reunion Island and increased mortality from Asian countries. CHICKV affects all age groups, and currently there are no specific drugs or vaccine to cure the disease. The need of antiviral agents for the treatment of CHICKV infection and the success of virtual screening against many therapeutically valuable targets led us to carry out the structure based drug design against Chikungunya nSP2 protease (PDB: 3TRK). Highthroughput virtual screening of publicly available databases, ZINC12 and BindingDB, has been carried out using the Openeye tools and Schrodinger LLC software packages. Openeye Filter program has been used to filter the database and the filtered outputs were docked using HTVS protocol implemented in GLIDE package of Schrodinger LLC. The top HITS were further used for enriching the similar molecules from the database through vROCS; a shape based screening protocol implemented in Openeye. The approach adopted has provided different scaffolds as HITS against CHICKV protease. Three scaffolds: Indole, Pyrazole and Sulphone derivatives were selected based on the docking score and synthetic feasibility. Derivatives of Pyrazole were synthesized and submitted for antiviral screening against CHICKV.

Integration Process of Industrial Design and Engineering Design

Year: 2010 Volume: 4 Issue: 7 1854 - 1859 Pages

Abstract: Lately management strategy that put Industrial Design (ID) in its core is recognized more important, as technology and price alone cannot differentiate a product. The needs to shorten the time to develop a product also shorten the development period of ID, and it necessitates the ID process management. This research analyzes the status of integration process of ID and Engineering Design (ED) of office equipment that requires the collaboration of ID and ED to clarify the issues for the efficiency of the development and to propose solutions.

Effect of Different Lactic Acid Bacteria on Phytic Acid Content and Quality of whole Wheat Toast Bread

Year: 2010 Volume: 4 Issue: 8 667 - 672 Pages

Abstract: Nowadays, consumption of whole flours and flours with high extraction rate is recommended, because of their high amount of fibers, vitamins and minerals. Despite nutritional benefits of whole flour, concentration of some undesirable components such as phytic acid is higher than white flour. In this study, effect of several lactic acid bacteria sourdough on Toast bread is investigated. Sourdough from lactic acid bacteria (Lb. plantarum, Lb. reuteri) with different dough yield (250 and 300) is made and incubated at 30°C for 20 hour, then added to dough in the ratio of 10, 20 and 30% replacement. Breads that supplemented with Lb. plantarum sourdough had lower phytic acid. Higher replacement of sourdough and higher DY cause higher decrease in phytic acid content. Sourdough from Lb. plantarum, DY = 300 and 30% replacement cause the highest decrease in phytic acid content (49.63 mg/100g). As indicated by panelists, Lb. reuteri sourdough can present the greatest effect on overall quality score of the breads. DY reduction cause a decrease in bread quality score. Sensory score of Toast bread is 81.71 in the samples that treated with Lb. reuteri sourdough with DY = 250 and 20% replacement.

Inter-Phase Magnetic Coupling Effects on Sensorless SR Motor Control

Year: 2007 Volume: 1 Issue: 11 682 - 685 Pages

Authors:
N. H. Mvungi

Abstract: Control of commutation of switched reluctance (SR) motor has been an area of interest for researchers for sometime now with mixed successes in addressing the inherent challenges. New technologies, processing schemes and methods have been adopted to make sensorless SR drive a reality. There are a number of conceptual, offline, analytical and online solutions in literature that have varying complexities and achieved equally varying degree of robustness and accuracies depending on the method used to address the challenges and the SR drive application. Magnetic coupling is one such challenge when using active probing techniques to determine rotor position of a SR motor from stator winding. This paper studies the effect of back-of-core saturation on the detected rotor position and presents results on measurement made on a 4- phase SR motor. The results shows that even for a four phase motor which is excited one phase at a time and using the electrically opposite phase for active position probing, the back-of-core saturation effects should not be ignored.

Analytical and Experimental Study on the Effect of Air-Core Coil Parameters on Magnetic Force Used in a Linear Optical Scanner

Year: 2012 Volume: 6 Issue: 5 1022 - 1027 Pages

Abstract: Today air-core coils (ACC) are a viable alternative to ferrite-core coils in a range of applications due to their low induction effect. An analytical study was carried out and the results were used as a guide to understand the relationship between the magnet-coil distance and the resulting attractive magnetic force. Four different ACC models were fabricated for experimental study. The variation in the models included the dimensions, the number of coil turns and the current supply to the coil. Comparison between the analytical and experimental results for all the models shows an average discrepancy of less than 10%. An optimized ACC design was selected for the scanner which can provide maximum magnetic force.

Network Analysis in a Natural Perturbed Ecosystem

Year: 2012 Volume: 6 Issue: 7 465 - 468 Pages

Abstract: The objective of this work is to explicit knowledge on the interactions between the chlorophyll-a and nine meroplankton larvae of epibenthonic fauna. The studied case is the Arraial do Cabo upwelling system, Southeastern of Brazil, which provides different environmental conditions. To assess this information a network approach based in probability estimative was used. Comparisons among the generated graphs are made in the light of different water masses, application of Shannon biodiversity index, and the closeness and betweenness centralities measurements. Our results show the main pattern among different water masses and how the core organisms belonging to the network skeleton are correlated to the main environmental variable. We conclude that the approach of complex networks is a promising tool for environmental diagnostic.

Effect on Physicochemical and Sensory Attributes of Bread Substituted with Different Levels of Matured Soursop (Anona muricata) Flour

Year: 2014 Volume: 8 Issue: 7 678 - 682 Pages

Abstract: Soursop (Anona muricata) is one of the underutilized tropical fruits containing nutrients, particularly dietary fibre and antioxidant properties that are beneficial to human health. This objective of this study is to investigate the feasibility of matured soursop pulp flour (SPF) to be substituted with high-protein wheat flour in bread. Bread formulation was substituted with different levels of SPF (0%, 5%, 10% and 15%). The effect on physicochemical properties and sensory attributes were evaluated. Higher substitution level of SPF resulted in significantly higher (p

A Modularized Design for Multi-Drivers Off-Road Vehicle Driving-Line and its Performance Assessment

Year: 2007 Volume: 1 Issue: 8 441 - 446 Pages

Abstract: Modularized design approach can facilitate the modeling of complex systems and support behavior analysis and simulation in an iterative and thus complex engineering process, by using encapsulated submodels of components and of their interfaces. Therefore it can improve the design efficiency and simplify the solving complicated problem. Multi-drivers off-road vehicle is comparatively complicated. Driving-line is an important core part to a vehicle; it has a significant contribution to the performance of a vehicle. Multi-driver off-road vehicles have complex driving-line, so its performance is heavily dependent on the driving-line. A typical off-road vehicle-s driving-line system consists of torque converter, transmission, transfer case and driving-axles, which transfer the power, generated by the engine and distribute it effectively to the driving wheels according to the road condition. According to its main function, this paper puts forward a modularized approach for designing and evaluation of vehicle-s driving-line. It can be used to effectively estimate the performance of driving-line during concept design stage. Through appropriate analysis and assessment method, an optimal design can be reached. This method has been applied to the practical vehicle design, it can improve the design efficiency and is convenient to assess and validate the performance of a vehicle, especially of multi-drivers off-road vehicle.

Thermal Treatment Influence on the Quality of Rye Bread Packaged in Different Polymer Films

Year: 2012 Volume: 6 Issue: 7 558 - 564 Pages

Abstract: this study was carried out to investigate the changes in quality parameters of rye bread packaged in different polymer films during convection air-flow thermal treatment process. Whole loafs of bread were placed in polymer pouches, which were sealed in reduced pressure air ambiance, bread was thermally treated in at temperature +(130; 140; and 150) ± 5 ºC within 40min, as long as the core temperature of the samples have reached accordingly +80±1 ºC. For bread packaging pouches were used: anti-fog Mylar®OL12AF and thermo resistant combined polymer material. Main quality parameters was analysed using standard methods: temperature in bread core, bread crumb and crust firmness value, starch granules volume and microflora. In the current research it was proved, that polymer films significantly influence rye bread quality parameters changes during thermal treatment. Thermo resistant combined polymer material film could be recommendable for packaged rye bread pasteurization, for maximal bread quality parameter keeping.

How Valid Are Our Language Test Interpretations? A Demonstrative Example

Year: 2010 Volume: 4 Issue: 7 1842 - 1853 Pages

Abstract: Validity is an overriding consideration in language testing. If a test score is intended for a particular purpose, this must be supported through empirical evidence. This article addresses the validity of a multiple-choice achievement test (MCT). The test is administered at the end of each semester to decide about students' mastery of a course in general English. To provide empirical evidence pertaining to the validity of this test, two criterion measures were used. In so doing, a Cloze test and a C-test which are reported to gauge general English proficiency were utilized. The results of analyses show that there is a statistically significant correlation among participants' scores on the MCT, Cloze, and Ctest. Drawing on the findings of the study, it can be cautiously deduced that these tests measure the same underlying trait. However, allowing for the limitations of using criterion measures to validate tests, we cannot make any absolute claim as to the validity of this MCT test.

Preparation and Characterization of Nylon 6-Clay Hybrid/Neat Nylon 6 Bicomponent Nanocomposite Fibers

Year: 2013 Volume: 7 Issue: 6 464 - 467 Pages

Abstract: Nylon 6-clay hybrid/neat nylon 6, sheath/core bicomponent nanocomposite fibers containing 4 wt% of clay in sheath section were melt spun at different take-up speeds. Their orientation and crystalline structure were compared to those of neat nylon 6 fibers. Birefringence measurements showed that the orientation development in sheath and core parts of bicomponent fibers was different. Crystallinity results showed that clay did not act as a nucleating agent for bicomponent fibers. The neat nylon 6 fiber had a smooth surface while striped pattern was appeared on the surface of bicomponent fiber containing clay due to thermal shrinkage of the core part.

Effects of Dry Period Length on, Milk Production and Composition, Blood Metabolites and Complete Blood Count in Subsequent Lactation of Holstein Dairy Cows

Year: 2010 Volume: 4 Issue: 8 656 - 661 Pages

Abstract: Twenty - nine Holstein cows were used to evaluate the effects of different dry period (DP) lengths on milk yield and composition, some blood metabolites, and complete blood count (CBC). Cows were assigned to one of 2 treatments: 1) 60-d dry period, 2) 35-d DP. Milk yield, from calving to 60 days, was not different for cows on the treatments (p =0.130). Cows in the 35-d DP produced more milk protein and SNF compare with cows in treatment 1 (p ≤ 0.05). Serum glucose, non-esterified fatty acids (NEFA), beta hydroxyl butyrate acid (BHBA), blood urea nitrogen (BUN), urea, and glutamic oxaloacetic transaminase (GOT) were all similar among the treatments. Body condition score (BCS), body weight (BW), complete blood count (CBC) and health problems were similar between the treatments. The results of this study demonstrated we can reduce the dry period length to 35 days with no problems.

A 25-year Monitoring of the Air Pollution Depicted by Plane Tree Species in Tehran

Year: 2010 Volume: 4 Issue: 9 428 - 431 Pages

Abstract: Tehran, one of the heavily-populated capitals, is severely suffering from increasing air pollution. To show a documented trend of such pollutants during last years, plane tree species (Platanus orientalis) were suited to be studied as indicators, for the species have been planted throughout the city many years ago. Two areas (Saadatabad and Narmak districts) allotting different contents of crowed and highly-traffic routs but the same ecological characteristics were selected. Twelve sample individuals were cored twice perpendicularly in each area. Tree-rings of each core were measured by a binocular microscope and separated annually for the last 25 years. Two heavy metals including Cd and Pb accompanied by a mineral element (Ca) were analyzed using Hatch method. Treerings analysis of the two areas showed different groups in term of physiologically ability as the growths were plunged during the last 10 years in Saadatabad district and showed a slight decrease in the same period for another studying area. In direct contrast to decreasing growth trend in Saadatabad, all three mentioned elements increased sharply during last 25 years in the same area. When it came to Narmak district, the trend was completely different with Saadatabad. There were some fluctuations in absorbing trace elements like tree-rings widths were, yet calcium showed an upward trend all the last 25 years. The results of the study proved the possibility of using tree species of each region to monitor its air pollution trends of the past, hence to depict a pollution assessment of a populated city for last years and then to make appropriate decisions for the future as it is well-known what the trend is. On the other hand, risen values of calcium (as the stress-indicator element) accompanied by increased trace elements suggests non-sustainable state of the trees.

Effects of Computer–Based Instructional Designs among Pupils of Different Music Intelligence Levels

Year: 2010 Volume: 4 Issue: 3 301 - 309 Pages

Abstract: The purpose of this study was to investigate the effects of computer–based instructional designs, namely modality and redundancy principles on the attitude and learning of music theory among primary pupils of different Music Intelligence levels. The lesson of music theory was developed in three different modes, audio and image (AI), text with image (TI) and audio with image and text (AIT). The independent variables were the three modes of courseware. The moderator variable was music intelligence. The dependent variables were the post test score. ANOVA was used to determine the significant differences of the pretest scores among the three groups. Analyses of covariance (ANCOVA) and Post hoc were carried out to examine the main effects as well as the interaction effects of the independent variables on the dependent variables. High music intelligence pupils performed significantly better than low music intelligence pupils in all the three treatment modes. The AI mode was found to help pupils with low music intelligence significantly more than the TI and AIT modes.

Object Recognition in Color Images by the Self Configuring System MEMORI

Year: 2007 Volume: 1 Issue: 6 1793 - 1802 Pages

Authors:
Michela Lecca

Abstract: System MEMORI automatically detects and recognizes rotated and/or rescaled versions of the objects of a database within digital color images with cluttered background. This task is accomplished by means of a region grouping algorithm guided by heuristic rules, whose parameters concern some geometrical properties and the recognition score of the database objects. This paper focuses on the strategies implemented in MEMORI for the estimation of the heuristic rule parameters. This estimation, being automatic, makes the system a self configuring and highly user-friendly tool.

A Study on Polymer Coated Colour Pigments for Water-Based Ink

Year: 2008 Volume: 2 Issue: 11 350 - 353 Pages

Abstract: The pigments covered by film-forming polymers have opened a prospect to improve the quality of water-based printing inks. In this study such pigments were prepared by the initiated polymerization of styrene and methacrylate derivative monomers in the aqueous pigment dispersions. The formation of polymer films covering pigment cores depends on the polymerization time and the ratio of pigment to monomers. At the time of 4 hours and the ratio of 1/10 almost pigment particles are coated by the polymer. The formed polymer covers of pigments have the average thickness of 5.95 nm. The size increasing percentage of the coated particles after a week is 4.5 %, about fourteen-fold lower than of the original ones. The obtained results indicate that the coated pigments are improved dispersion stability in water medium along with a guarantee for the optical colour.

Some Investigations on Higher Mathematics Scores for Chinese University Student

Year: 2009 Volume: 3 Issue: 7 535 - 538 Pages

Authors:
Xun Ge
Jingju Qian

Abstract: To investigate some relations between higher mathe¬matics scores in Chinese graduate student entrance examination and calculus (resp. linear algebra, probability statistics) scores in subject's completion examination of Chinese university, we select 20 students as a sample, take higher mathematics score as a decision attribute and take calculus score, linear algebra score, probability statistics score as condition attributes. In this paper, we are based on rough-set theory (Rough-set theory is a logic-mathematical method proposed by Z. Pawlak. In recent years, this theory has been widely implemented in the many fields of natural science and societal science.) to investigate importance of condition attributes with respective to decision attribute and strength of condition attributes supporting decision attribute. Results of this investigation will be helpful for university students to raise higher mathematics scores in Chinese graduate student entrance examination.

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